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| Product | Description | |
|---|---|---|
| WAY-100635 | WAY-100635 is an achiral analogue of WAY-100135 which is significantly more potent and selective than the latter compound and which displays unequivocal 5-HTIA receptor antagonist activity in a range of pre-(somatodendritic) and postsynaptic functional mo. Synonyms: WAY-100635; WAY100635; WAY 100635. N- [2- [4- (2-methoxyphenyl) piperazin-1-yl] ethyl] -N-pyridin-2-ylcyclohexane carboxamidecyclohexane carboxamide, N-(2-(4-(2-methoxyphenyl)-1-piperazinyl)ethyl)-N-2-pyridinyl-N-(2-(4-(2-methoxyphenyl)-1-piperazinyl)ethyl)-N-(2-pyridinyl)cyclohexanecarboxamide. CAS No. 162760-96-5. Molecular formula: C25H34N4O2. Mole weight: 422.56. |  |
| WAY-100635 | WAY-100635 is a potent and selective 5-HT 1A Receptor antagonist with a pIC 50 of 8.87, an apparent pA 2 of 9.71. WAY-100635 is a potent and selective 5-hydroxytryptamine 1A (5-HT1A) receptor antagonist with an IC 50 value of 0.91 nM and K i value of 0.39 nM. WAY-100635 has pIC 50 values for 5-HT1A and α1-adrenergic receptors of 8.9 and 6.6, respectively. WAY-100635 is also a potent dopamine D 4 receptor agonist [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 162760-96-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-10349. |  |
| WAY-100635 maleate | WAY-100635 maleate is a potent and selective 5-hydroxytryptamine 1A (5-HT1A) receptor antagonist with an IC 50 value of 0.91 nM and K i value of 0.39 nM. WAY-100635 maleate has pIC 50 values for 5-HT1A and α1-adrenergic receptors of 8.9 and 6.6, respectively. WAY-100635 maleate is also a potent dopamine D 4 receptor agonist [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1092679-51-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-10349A. | |
| WAY-100635 maleate | WAY-100635 maleate is a potent and selective 5-hydroxytryptamine1A antagonist for 5-HT ( IC50= 0.95 ± 0.12 nM ), and also exhibits agonist activity at dopamine D4 receptors. Uses: Potent, silent antagonist of 5-ht1a receptors. Synonyms: WAY-100635 maleate; WAY 100635 maleate; WAY100635 maleate; (Z)-but-2-enedioic acid;N-[2-[4-(2-methoxyphenyl)piperazin-1-yl]ethyl]-N-pyridin-2-ylcyclohexanecarboxamide. Grades: ≥98%. CAS No. 634908-75-1. Molecular formula: C29H38N4O6. Mole weight: 538.64. | |
| WAY-100635 Maleate (5-HT1A Serotonis Receptor Antagonist, WAY-100635 Maleate, WAY 100635, WAY100635) | A selective 5-HT1A receptor antagonist (pKi = 7.9-9.2). WAY-100635 has been reported to have good inhibitory action centrally and peripherally (1mg/kg dose in rats) but has low intrinsic effects, making it a silent 5-HT1A receptor antagonist. WAY-100635 displaced specific binding of the 5-HT1A radioligand, [3H]8-OH-DPAT (8-hydroxy-2-(di-n-propylamino)tetralin), to rat hippocampal membranes with a pIC50 of 8.87. This represented a greater than 100-fold selectivity relative to binding at other 5-HT receptor subtypes and major neurotransmitter receptor, reuptake and ion channel sites. WAY-100635 has been used in a variety of vertebrate species in vivo and in vitro. Group: Biochemicals. Grades: Highly Purified. CAS No. 634908-75-1. Pack Sizes: 10mg. US Biological Life Sciences. |  Worldwide |
| WAY-100635 maleate salt | powder. Group: Fluorescence/luminescence spectroscopy. |  |
| WAY 100635 hydrochloride | WAY 100635 hydrochloride is a 5-HT1A receptor antagonist with dopamine D4 agonist activity (Ki values 2.2 nM, 6260 nM, 24 nM, >10,000 nM, 20 nM, 322 nM, and 16 nM for 5-HT1A, 5-HT2A, 5-HT2B, 5-HT7, α1A, α1B, and D4, respectively). Uses: Serotonin antagonists. Synonyms: WAY 100635 trihydrochloride; WAY100635 trihydrochloride; WAY-100635 trihydrochloride; N-[2-[4-(2-methoxyphenyl)piperazin-1-yl]ethyl]-N-pyridin-2-ylcyclohexanecarboxamide trihydrochloride. Grades: 99%. CAS No. 146714-97-8. Molecular formula: C25H34N4O2.3HCl. Mole weight: 531.947. | |
| WAY-600 | WAY-600 is a potent, ATP-competitive and selective inhibitor of mTOR with IC50 of 9 nM. Uses: Designed for use in research and industrial production. Additional or Alternative Names: WAY600; WAY 600; WAY600. Product Category: Inhibitors. Appearance: White solid powder. CAS No. 1062159-35-6. Molecular formula: C28H30N8O. Mole weight: 494.59. Purity: >98%. IUPACName: 4-(6-(1H-indol-5-yl)-1-(1-(pyridin-3-ylmethyl)piperidin-4-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-yl)morpholine. Canonical SMILES: N1(C2=C3C(N(C4CCN(CC5=CC=CN=C5)CC4)N=C3)=NC(C6=CC7=C(NC=C7)C=C6)=N2)CCOCC1. Product ID: ACM1062159356. Alfa Chemistry ISO 9001:2015 Certified. Categories: WAY-100635. |  |
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