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| Product | Description | |
|---|---|---|
| WAY-100635 maleate | WAY-100635 maleate is a potent and selective 5-hydroxytryptamine 1A (5-HT1A) receptor antagonist with an IC 50 value of 0.91 nM and K i value of 0.39 nM. WAY-100635 maleate has pIC 50 values for 5-HT1A and α1-adrenergic receptors of 8.9 and 6.6, respectively. WAY-100635 maleate is also a potent dopamine D 4 receptor agonist [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1092679-51-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-10349A. |  |
| WAY-100635 maleate | WAY-100635 maleate is a potent and selective 5-hydroxytryptamine1A antagonist for 5-HT ( IC50= 0.95 ± 0.12 nM ), and also exhibits agonist activity at dopamine D4 receptors. Uses: Potent, silent antagonist of 5-ht1a receptors. Synonyms: WAY-100635 maleate; WAY 100635 maleate; WAY100635 maleate; (Z)-but-2-enedioic acid;N-[2-[4-(2-methoxyphenyl)piperazin-1-yl]ethyl]-N-pyridin-2-ylcyclohexanecarboxamide. Grades: ≥98%. CAS No. 634908-75-1. Molecular formula: C29H38N4O6. Mole weight: 538.64. |  |
| WAY-100635 Maleate (5-HT1A Serotonis Receptor Antagonist, WAY-100635 Maleate, WAY 100635, WAY100635) | A selective 5-HT1A receptor antagonist (pKi = 7.9-9.2). WAY-100635 has been reported to have good inhibitory action centrally and peripherally (1mg/kg dose in rats) but has low intrinsic effects, making it a silent 5-HT1A receptor antagonist. WAY-100635 displaced specific binding of the 5-HT1A radioligand, [3H]8-OH-DPAT (8-hydroxy-2-(di-n-propylamino)tetralin), to rat hippocampal membranes with a pIC50 of 8.87. This represented a greater than 100-fold selectivity relative to binding at other 5-HT receptor subtypes and major neurotransmitter receptor, reuptake and ion channel sites. WAY-100635 has been used in a variety of vertebrate species in vivo and in vitro. Group: Biochemicals. Grades: Highly Purified. CAS No. 634908-75-1. Pack Sizes: 10mg. US Biological Life Sciences. |  Worldwide |
| WAY-100635 maleate salt | powder. Group: Fluorescence/luminescence spectroscopy. |  |
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