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| Product | Description | |
|---|---|---|
| Xanomeline | Xanomeline, as an effective and selective muscarinic type 1 and type 4 ( M1/M4 ) receptor agonist, increases neuronal excitability. Xanomeline can be used for the research of neurological disorders, such as schizophrenia [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LY-246708. CAS No. 131986-45-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-105182. |  |
| Xanomeline | Xanomeline is a Muscarinic M1 and M4 receptor agonist under the development of Eli Lilly, though it is also known to act as a M5 receptor antagonist. Xanomeline has been shown to have reasonable efficacy for the treatment of schizophrenia symptoms although gastrointestinal side effects led to a high drop-out rate in clinical trials. Recent studies showed robust improvements in verbal learning and short-term memory associated with xanomeline treatment. In Dec 1998, Phaes-III clinical trials for Alzheimer's disease in USA was discontinued. Uses: Alzheimer's disease. Synonyms: LY-246708; LY246708; LY 246708; Xanomeline; Memcor; NNC-110232; Hexyloxy-TZTP; HexyloxyTZTP;3-(hexyloxy)-4-(1-methyl-1,2,5,6-tetrahydropyridin-3-yl)-1,2,5-thiadiazole. Grades: 95%. CAS No. 131986-45-3. Molecular formula: C14H23N3OS. Mole weight: 281.42. |  |
| Xanomeline | Xanomeline. Uses: For analytical and research use. Group: Impurity standards. CAS No. 131986-45-3. Molecular Formula: C14H23N3OS. Mole Weight: 281.42. Catalog: APB131986453. |  |
| Xanomeline Impurity 1 | Xanomeline Impurity 1. Uses: For analytical and research use. Group: Impurity standards. CAS No. 174656-58-7. Molecular Formula: C14H23N3O2S. Mole Weight: 297.42. Catalog: APB174656587. | |
| Xanomeline Impurity 10 | Xanomeline Impurity 10. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C20H27D4N3O8S. Mole Weight: 477.57. Catalog: APB11430. | |
| Xanomeline Impurity 11 | Xanomeline Impurity 11. Uses: For analytical and research use. Group: Impurity standards. CAS No. 131986-66-8. Molecular Formula: C15H25N3OS. Mole Weight: 295.45. Catalog: APB131986668. | |
| Xanomeline Impurity 2 | Xanomeline Impurity 2. Uses: For analytical and research use. Group: Impurity standards. CAS No. 131986-96-4. Molecular Formula: C13H21N3OS. Mole Weight: 267.39. Catalog: APB131986964. | |
| Xanomeline Impurity 3 | Xanomeline Impurity 3. Uses: For analytical and research use. Group: Impurity standards. CAS No. 174656-57-6. Molecular Formula: C11H15N3O3S. Mole Weight: 269.32. Catalog: APB174656576. | |
| Xanomeline Impurity 4 | Xanomeline Impurity 4. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C11H11D4N3O3S. Mole Weight: 273.34. Catalog: APB11425. | |
| Xanomeline Impurity 5 | Xanomeline Impurity 5. Uses: For analytical and research use. Group: Impurity standards. CAS No. 159058-46-5. Molecular Formula: C12H17N3O3S. Mole Weight: 283.35. Catalog: APB159058465. | |
| Xanomeline Impurity 6 | Xanomeline Impurity 6. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C12H14D3N3O3S. Mole Weight: 286.36. Catalog: APB11427. | |
| Xanomeline Impurity 7 | Xanomeline Impurity 7. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C12H13D4N3O3S. Mole Weight: 287.37. Catalog: APB11426. | |
| Xanomeline Impurity 8 | Xanomeline Impurity 8. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C20H31N3O8S. Mole Weight: 473.54. Catalog: APB11428. | |
| Xanomeline Impurity 9 | Xanomeline Impurity 9. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C20H28D3N3O8S. Mole Weight: 476.56. Catalog: APB11429. | |
| Xanomeline oxalate | Muscarinic receptors are G protein-coupled acetylcholine receptors that play diverse roles. Xanomeline oxalate is a potent agonist of muscarinic acetylcholine receptors (EC50 values are 0.3, 92.5, 5, 52, and 42 nM for M1, M2, M3, M4, and M5, respectively). It has antipsychotic-like activities in rats and Cebus monkeys. M1 selective agonists, like Xanomeline oxalate, enhance memory function and has utility in treating Alzheimer's Disease. Synonyms: LY246708; LY 246708; LY-246708; Memcor; Lumeron. Grades: >98%. CAS No. 141064-23-5. Molecular formula: C16H25N3O5S. Mole weight: 371.45. | |
| Xanomeline oxalate | Xanomeline oxalate. Group: Biochemicals. Grades: Purified. CAS No. 141064-23-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. |  Worldwide |
| Xanomeline oxalate | Xanomeline oxalate (LY246708 oxalate) is a potent and selective muscarinic receptor agonist (SMRA) and stimulates phosphoinositide hydrolysis in vivo. Xanomeline oxalate can be used for the research of Alzheimers disease [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LY246708 oxalate. CAS No. 141064-23-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13410. | |
| Xanomeline Oxalate (3-(hexyloxy)-4-(1-methyl-1,2,5,6-tetrahydropyridin-3-yl)-1,2,5-thiadiazole, Muscarinic Acetylcholine Receptor (mAChR) Agonist, Xanomeline) | An agonist selective for muscarinic acetylcholine receptor (mAChR) subtype M1 (EC50 = 0.3, 5, 42, 52 and 92.5nM at M1, M3, M5, M4 and M2 receptors respectively). An antipsychotic agent. Used in improving cognitive deficits and behavioral disturbances in Alzheimer's disease and schizophrenia. Group: Biochemicals. Grades: Highly Purified. CAS No. 141064-23-5. Pack Sizes: 10mg. Molecular Formula: C??H??N?OS C?H?O. US Biological Life Sciences. | Worldwide |
| Xanomeline tartrate | Xanomeline (LY 246708) is the potent agonist of muscarinic M1/M4 receptor with antipsychotic-like activity. Xanomeline (LY 246708) increases neuronal excitability. Xanomeline (LY 246708) can be used for the research of schizophrenia [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LY 246708 tartrate. CAS No. 152854-19-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-105182A. | |
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