Xanomeline Suppliers USA
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Product | Description | |
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Xanomeline Oxalate (3-(hexyloxy)-4-(1-methyl-1,2,5,6-tetrahydropyridin-3-yl)-1,2,5-thiadiazole, Muscarinic Acetylcholine Receptor (mAChR) Agonist, Xanomeline) Quick inquiry Where to buy Suppliers range | An agonist selective for muscarinic acetylcholine receptor (mAChR) subtype M1 (EC50 = 0.3, 5, 42, 52 and 92.5nM at M1, M3, M5, M4 and M2 receptors respectively). An antipsychotic agent. Used in improving cognitive deficits and behavioral disturbances in Alzheimer's disease and schizophrenia. Group: Biochemicals. Grades: Highly Purified. CAS No. 141064-23-5. Pack Sizes: 10mg. Molecular Formula: C??H??N?OS C?H?O. US Biological Life Sciences. | Worldwide |
Xanomeline Quick inquiry Where to buy Suppliers range | Xanomeline is a Muscarinic M1 and M4 receptor agonist under the development of Eli Lilly, though it is also known to act as a M5 receptor antagonist. Xanomeline has been shown to have reasonable efficacy for the treatment of schizophrenia symptoms although gastrointestinal side effects led to a high drop-out rate in clinical trials. Recent studies showed robust improvements in verbal learning and short-term memory associated with xanomeline treatment. In Dec 1998, Phaes-III clinical trials for Alzheimer's disease in USA was discontinued. Uses: Alzheimer's disease. Synonyms: LY-246708; LY246708; LY 246708; Xanomeline; Memcor; NNC-110232; Hexyloxy-TZTP; HexyloxyTZTP;3-(hexyloxy)-4-(1-methyl-1,2,5,6-tetrahydropyridin-3-yl)-1,2,5-thiadiazole. Grades: 95%. CAS No. 131986-45-3. Molecular formula: C14H23N3OS. Mole weight: 281.42. | |
Xanomeline oxalate Quick inquiry Where to buy Suppliers range | Xanomeline oxalate. Group: Biochemicals. Grades: Purified. CAS No. 141064-23-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
Xanomeline oxalate Quick inquiry Where to buy Suppliers range | Muscarinic receptors are G protein-coupled acetylcholine receptors that play diverse roles. Xanomeline oxalate is a potent agonist of muscarinic acetylcholine receptors (EC50 values are 0.3, 92.5, 5, 52, and 42 nM for M1, M2, M3, M4, and M5, respectively). It has antipsychotic-like activities in rats and Cebus monkeys. M1 selective agonists, like Xanomeline oxalate, enhance memory function and has utility in treating Alzheimer's Disease. Synonyms: LY246708; LY 246708; LY-246708; Memcor; Lumeron. Grades: >98%. CAS No. 141064-23-5. Molecular formula: C16H25N3O5S. Mole weight: 371.45. |