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| Product | Description | |
|---|---|---|
| XE 991 | XE 991 is a KCNQ channel and M-current blocker potentially for the treatment of AD. Uses: Potential treatment of ad. Synonyms: XE-991; LS-190926; XE 991; LS 190926; XE991; LS190926; 10,10-bis(pyridin-4-ylmethyl)anthracen-9-one. Grades: 99%. CAS No. 122955-42-4. Molecular formula: C26H20N2O. Mole weight: 376.45. |  |
| XE 991 dihydrochloride | XE 991 dihydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 122955-13-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. |  Worldwide |
| XE 991 dihydrochloride | XE 991 dihydrochloride is a potent and selective blocker of KV7 (KCNQ) voltage-gated potassium channels. XE 991 blocks KV7.2+7.3 (KCNQ2+3) / M-currents (IC50 = 0.6 - 0.98 μM) and KV7.1 (KCNQ1) homomeric channels (IC50 = 0.75 μM) but is less potent against KV7.1/minK channels (IC50 = 11.1 μM). XE 991 increases hippocampal ACh release and enhances cognition following oral administration in vivo, suggesting to be beneficial for Alzheimer's disease therapy. Uses: Potential treatment of alzheimer's disease. Synonyms: XE991; XE 991; XE-991; LS 190926; LS190926; LS-190926; 10,10-bis(4-Pyridinylmethyl)-9(10H)-anthracenone dihydrochloride. Grades: ≥99% by HPLC. CAS No. 122955-13-9. Molecular formula: C26H20N2O.2HCl. Mole weight: 449.37. | |
| 10,10-Bis(4-pyridinylmethyl)-9(10H)-anthracenone dihydrochloride | Heterocyclic Organic Compound. Alternative Names: 122955-42-4, 9(10H)-Anthracenone,10,10-bis(4-pyridinylmethyl)-, 10,10-BIS(4-PYRIDINYLMETHYL)-9(10H)-ANTHRACENONE DIHYDROCHLORIDE, ACMC-20emsx, CTK4B3355, MolPort-003-983-711, AG-D-49639, DR 960418;XE 991. CAS No. 122955-42-4. Molecular formula: C26H24Cl2N2O. Mole weight: 451.39. Purity: >99 %. IUPACName: 10,10-bis(pyridin-4-ylmethyl)anthracen-9-one;dihydrochloride. Canonical SMILES: C1=CC=C2C (=C1)C (=O)C3=CC=CC=C3C2 (CC4=CC=NC=C4)CC5=CC=NC=C5. Cl. Cl. Catalog: ACM122955424. |  |
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