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| Product | Description | |
|---|---|---|
| Y-26763 | Y-26763. Group: Biochemicals. Grades: Purified. CAS No. 127408-31-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. |  Worldwide |
| Y-26763 | Y-26763 is a Kir6 (KATP) channel opener and active metabolite of Y-27152. Y-26763 inhibits glucose-induced insulin secretion in isolated human pancreatic β-cells in vitro. Y-26763 exhibits antihypertensive effects on spontaneously hypertensive rats and displays cardioprotective properties in dogs following systemic administration in vivo. Synonyms: Y-26763; Y 26763; Y26763. N-[(3S,4R)-6-Cyano-3,4-dihydro-3-hydroxy-2,2-dimethyl-2H-1-benzopyran-4-yl]-N-hydroxyacetamide. Grades: ≥98% by HPLC. CAS No. 127408-31-5. Molecular formula: C14H16N2O4. Mole weight: 276.29. |  |
| Y-27152 | Y-27152 is a prodrug of the Kir6 (KATP) channel opener Y-26763. It was demonstrated ability to produce long-lasting antihypertensive effects in vivo, with minimal tachycardia following oral administration in hypertensive animals. Synonyms: Y 27152; Y-27152; Y27152. N-[(3S,4R)-6-Cyano-3,4-dihydro-3-hydroxy-2,2-dimethyl-2H-1-benzopyran-4-yl]-N-(phenylmethoxy)acetamide. Grades: ≥98% by HPLC. CAS No. 127408-30-4. Molecular formula: C21H22N2O4. Mole weight: 366.41. | |
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