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Y-33075 Y-33075, also called as SNJ-1656, a well-characterized ROCK inhibitor, inhibits more potently ROCK by about 30 times than Y-27632, a common specific ROCK inhibitor (IC50= 3.6nM). Synonyms: 4-[(1R)-1-aminoethyl]-N-(1H-pyrrolo[2,3-b]pyridin-4-yl)benzamideSNJ-1656; Y-39983; Y-33075; SNJ 1656; Y 39983; Y 33075; SNJ1656; Y39983; Y33075. CAS No. 199433-58-4. Molecular formula: C16H16N4O. Mole weight: 280.32. BOC Sciences 10
Y-33075 dihydrochloride Y-33075 dihydrochloride is a selective ROCK inhibitor (IC50 = 3.6 nM) derived from Y-27632. Y-39983 increases the regenerating axons of retinal ganglion cells (RGCs) in the eyes of the rats. Synonyms: 4-[(1R)-1-aminoethyl]-N-(1H-pyrrolo[2,3-b]pyridin-4-yl)benzamide dihydrochloride; SNJ-1656; Y-3998. Grades: >98%. CAS No. 173897-44-4. Molecular formula: C16H18Cl2N4O. Mole weight: 353.25. BOC Sciences 11

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