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Y16 is an inhibitor of G-protein-coupled Rho GEFs. It specifically inhibits LARG catalyzed activation of RhoA and RhoA signaling pathways and blocks the growth and migration of MCF7 breast cancer cells. Synonyms: RhoA-IN-Y16; Y16; Y-16; Y 16. Grades: >98%. CAS No. 429653-73-6. Molecular formula: C24H20N2O3. Mole weight: 384.43.
Y16
Y16 is a specific inhibitor of Leukemia-associated Rho guanine nucleotide exchange factor (LARG) with a K d value of 76 nM. Y16 is active in blocking the interaction of LARG and related G-protein-coupled Rho GEFs with RhoA. Y16 shows no detectable effect on other diffuse B-cell lymphoma (Dbl) family Rho GEFs, Rho effectors, or a RhoGAP [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 429653-73-6. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-12649.
2,2-Dipyridyl disulfide
2,2-Dipyridyl disulfide is a useful reagent for the determination of sulfhydryl groups. 2,2-Dipyridyl disulfide is a common reagent in peptide chemistry, often used in oxidation - reduction condensations to form peptide bonds or in coupling reactions to form disulfide-linked heterodimers [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2127-3-9. Pack Sizes: 10 mM * 1 mL; 5 g. Product ID: HY-Y1666.
2,4-Dihydroxyquinoline
2,4-Dihydroxyquinoline is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 86-95-3. Pack Sizes: 10 g; 25 g. Product ID: HY-Y1685. Categories: dichlorophenoxyacetic acid.
2,6-Dibromophenol
2,6-Dibromophenol is an endogenous metabolite. Uses: Scientific research. Group: Natural products. CAS No. 608-33-3. Pack Sizes: 10 mM * 1 mL; 500 mg. Product ID: HY-Y1667.
3-(3,4-Dimethoxyphenyl)propanoic acid
3-(3,4-Dimethoxyphenyl)propanoic acid is an orally active short-chain fatty acids (SCFAs). 3-(3,4-Dimethoxyphenyl)propanoic acid stimulates γ globin gene expression, erythropoiesis in vivo and is used for the β hemoglobinopathies and other anemias [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2107-70-2. Pack Sizes: 10 mM * 1 mL; 5 g; 10 g. Product ID: HY-Y1620.
4-Hydroxy-6-methyl-2-pyrone
4-Hydroxy-6-methyl-2-pyrone is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 675-10-5. Pack Sizes: 10 mM * 1 mL; 5 g; 25 g. Product ID: HY-Y1634.
DL-Menthol
DL-Menthol is a relative configuration of (-)-Menthol. DL-Menthol relates to the activation of GABAA receptor [1]. Uses: Scientific research. Group: Natural products. Alternative Names: Racementhol. CAS No. 89-78-1. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g. Product ID: HY-Y1683.
Fmoc-Arg(Pbf)-OH
Fmoc-Arg(Pbf)-OH is an arginine derivative containing amine protecting group Fmoc. Fmoc-Arg(Pbf)-OH is a building block for the introduction of Arg into SPPS (Solid-Phase Peptide Synthesis) [1] [2] [3]. Uses: Scientific research. Group: Peptides. CAS No. 154445-77-9. Pack Sizes: 10 g; 25 g; 50 g; 100 g. Product ID: HY-Y1636.
Potassium bromide, 99%
Potassium bromide, 99% is a salt, widely used as an anticonvulsant and a sedative. Potassium bromide is a redox reagent that can be used to remove peripheral membrane proteins in molecular biology [1] [2]. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 7758-2-3. Pack Sizes: 10 mM * 1 mL; 100 g. Product ID: HY-Y1673.
Tetrabutylammonium hexafluorophosphate
Tetrabutylammonium hexafluorophosphate is an organic-inorganic compound commonly used as an ionic solvent and catalyst. It can be used to catalyze or promote reactions in certain chemical reactions, and is widely used in batteries, solar cells and pigments. In addition, this compound is also widely used in organic synthesis and chemical analysis. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 3109-63-5. Pack Sizes: 5 g; 10 g. Product ID: HY-Y1699.
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