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| Product | Description | |
|---|---|---|
| YIL 781 | YIL 781 is a ghrelin receptor antagonist (GHS-R1a) (Ki = 17 nM) with no significant affinity for the motilin receptor (Ki = 6 μM). YIL 781 inhibits ghrelin to reduce insulin secretion both in vivo and in vitro. YIL 781 may be beneficial for the treatment of obesity and diabetes. Uses: Potential treatment of obesity and diabetes. Synonyms: YIL 781; YIL781; YIL-781; 6-(4-Fluorophenoxy)-2-methyl-3-[[(3S)-1-(1-methylethyl)-3-piperidinyl]methyl]-4(3H)-quinazolinone; KB-276128; KB 276128; KB276128. Grades: ≥98% by HPLC. CAS No. 875258-85-8. Molecular formula: C24H28FN3O2. Mole weight: 409.51. |  |
| YIL 781, Hydrochloride Salt | Ghrelin receptor antagonist (GHS-R1a) (Ki = 17nM). Displays no significant affinity for the motilin receptor (Ki = 6uM). Blocks the effects of ghrelin on insulin secretion both in vivo and in vitro. Improves glucose homeostasis in vivo. Group: Biochemicals. Alternative Names: 6-(4-Fluorophenoxy)-2-methyl-3-[[(3S)-1-(1-methylethyl)-3-piperidinyl]methyl]-4(3H)-quinazolinone. Grades: Highly Purified. CAS No. 875258-85-8. Pack Sizes: 5mg. Molecular Formula: C??H??FN?O?.HCl, Molecular Weight: 445.96. US Biological Life Sciences. |  Worldwide |
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