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| Product | Description | |
|---|---|---|
| YM 202074 | High affinity, selective metabotropic glutamate receptor type 1 (mGlu1) antagonist. Binds an allosteric site of the rat mGlu1 receptor with a Ki of 4.8 nM. Inhibits mGlu1-mediated inositol phosphates production (IC50 = 8.6 nM in rat cerebellar granule cells). Neuroprotective in vivo. Group: Biochemicals. Grades: Highly Purified. CAS No. 299900-84-8. Pack Sizes: 5mg, 25mg. US Biological Life Sciences. |  Worldwide |
| YM 202074 | YM 202074 is a high affinity and selective metabotropic glutamate receptor type 1 (mGlu1) antagonist. YM 202074 binds to an allosteric site of the rat mGlu1 receptor (Ki = 4.8 nM) and inhibits mGlu1-mediated inositol phosphates production (IC50 = 8.6 nM in rat cerebellar granule cells). Synonyms: YM 202074; YM202074; YM-202074; N-Cyclohexyl-6-[[N-(2-methoxyethyl)-N-methylamino]methyl]-N-methylthiazolo[3,2-a]benzoimidazole-2-carboxamide sesquifumarate. Grades: ≥99% by HPLC. CAS No. 299900-84-8. Molecular formula: C22H30N4O2S.3/2C4H4O4. Mole weight: 588.67. |  |
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