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YM 26734 YM 26734. Group: Biochemicals. Grades: Purified. CAS No. 144337-18-8. Pack Sizes: 10mg. US Biological Life Sciences. USBiological 5
Worldwide
YM 26734 YM 26734 is a competitive inhibitor of secretory phospholipase A2 (sPLA2) with a broad inhibitory profile to several sPLA2s (IC50 = 0.2, 1, 1, 1 and 3 μM for sPLA2-X, -IIA, -IID, -V and -IIE, respectively). YM 26734 displays minimal activity at sPLA2-IIF and no activity at cytosolic PLA2, cyclooxygenase and lipoxygenase. YM 26734 is used to ameliorates local inflammatory responses in TPA-induced mouse ear edema. Synonyms: YM 26734; YM26734; YM-26734; 1,1'-[5-[3,4-Dihydro-7-hydroxy-2-(4-hydroxyphenyl)-2H-1-benzopyran-4-yl]-2,4,6-trihydroxy-1,3-phenylene]bis-1-dodecanone; 1-[3-dodecanoyl-2,4,6-trihydroxy-5-[7-hydroxy-2-(4-hydroxyphenyl)-3,4-dihydro-2H-chromen-4-yl]phenyl]dodecan-1-one. Grades: ≥95% by HPLC. CAS No. 144337-18-8. Molecular formula: C45H62O8. Mole weight: 730.97. BOC Sciences 10

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