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It is a cytidine analogue, cytidine deaminase inhibitor, and DNA demethylating agent. Group: Biochemicals. Alternative Names: 1- β-D-Ribofuranosyl-. Grades: Highly Purified. CAS No. 3690-10-6. Pack Sizes: 10mg. US Biological Life Sciences.
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Zebularine
Zebularine is a nucleoside analogue of cytidine. It is a transition state analogue inhibitor of cytidine deaminase by binding to the active site as covalent hydrates. It can inhibit DNA methylation and tumor growth in vitro and in vivo. Synonyms: 1-b-D-Ribofuranosyl-2-(1H)-pyrimidinone; 4-Deoxyuridine; NSC 309132; NSC309132; NSC-309132; Pyrimidin-2-one β-D-Ribofuranoside; 1-beta-D-ribofuranosylpyrimidin-2(1H)-one; 2-Pyrimidone-1-beta-D-riboside; 1-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-2(1H)-one. Grades: ≥95%. CAS No. 3690-10-6. Molecular formula: C9H12N2O5. Mole weight: 228.20.
Zebularine
Zebularine (NSC309132; 4-Deoxyuridine) is a DNA methyltransferase inhibitor. Zebularine also inhibits cytidine deaminase with a K i of 0.95 μM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: NSC309132; 4-Deoxyuridine. CAS No. 3690-10-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13420.
Zebularine 3'-CE phosphoramidite
Zebularine 3'-CE phosphoramidite. Group: Biochemicals. Grades: Highly Purified. CAS No. 155831-90-6. Pack Sizes: 100mg, 250mg. Molecular Formula: C45H61N4O8PSi. US Biological Life Sciences.
Worldwide
Zebularine 3'-CE phosphoramidite
Zebularine 3'-CE phosphoramidite is a key compound widely used in biomedical field playing a crucial role in the synthesis of oligonucleotides and specifically designed for the modification of nucleic acids. It enables the research of various diseases, including cancer, by targeting specific gene sequences and regulating gene expression. Synonyms: Zebularine CEP; 155831-90-6; 2/'-O-T-BUTYLDIMETHYLSILYL-3/'-O-[(DIISOPROPYLAMINO)(2-CYANOETHOXY)PHOSPHINO]-5/'-O-(4,4/'-DIMETHOXY; 3-[[ (2R, 3R, 4R, 5R) -2-[[bis (4-methoxyphenyl) -phenylmethoxy]methyl]-4-[tert-butyl (dimethyl) silyl]oxy-5- (2-oxopyrimidin-1-yl) oxolan-3-yl]oxy-[di (propan-2-yl) amino]phosphanyl]oxypropanenitrile; W-201408; (2R, 3R, 4R, 5R)-2- ( (Bis (4-methoxyphenyl) (phenyl)methoxy)methyl)-4- ( (tert-butyldimethylsilyl)oxy)-5- (2-oxopyrimidin-1 (2H)-yl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite. Grades: 95%. CAS No. 155831-90-6. Molecular formula: C45H61N4O8PSi. Mole weight: 845.04.
2"-Deoxy-Zebularine 5'Phosphate
2"-Deoxy-Zebularine 5'Phosphate is a metabolite of Zebularine which can be used for human deoxycytidylate deaminase inhibition. Synonyms: Sodium ((2R,3S,5R)-3-Hydroxy-5-(2-oxopyrimidin-1(2H)-yl)tetrahydrofuran-2-yl)methyl Phosphate. Molecular formula: C9H11N2Na2O7P. Mole weight: 336.15.
2-Deoxy-Zebularine 5Phosphate
2-Deoxy-Zebularine 5Phosphate is a a metabolite of Zebularine (Z276000) which can be used as an inhibitor of human deoxycytidylate deaminase. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C9H11N2Na2O7P, Molecular Weight: 336.15. US Biological Life Sciences.
Worldwide
α-2'-Deoxy Zebularine
α-2'-Deoxy Zebularine is the α-anomer of β-2'-Deoxy Zebularine; a Zebularine metabolite which can be used as an inhibitor of human deoxycytidylate deaminase. Synonyms: 1-(2-Deoxy-α-D-erythro-pentofuranosyl)-2(1H)-pyrimidinone. CAS No. 68780-64-3. Molecular formula: C9H12N2O4. Mole weight: 212.2.
β-2'-Deoxy Zebularine
β-2'-Deoxy Zebularine is a metabolite of Zebularine and can be used as human deoxycytidylate deaminase inhibitor. Synonyms: 1-(2-Deoxy-β-D-erythro-pentofuranosyl)-2(1H)-pyrimidinone. CAS No. 22003-30-1. Molecular formula: C9H12N2O4. Mole weight: 212.2.
4-Deoxyuridine
4-Deoxyuridine. Group: Biochemicals. Alternative Names: Zebularine; 1-b-D-Ribofuranosyl-2(1H)-pyrimidinone. Grades: Highly Purified. CAS No. 3690-10-6. Pack Sizes: 50mg, 100mg, 250mg, 500mg, 1g. Molecular Formula: C9H12N2O5. US Biological Life Sciences.
Worldwide
4-Deoxy-xylo-uridine
4-Deoxy-xylo-uridine is a remarkable compound, exhibiting exceptional potency in research of combatting viral infections originating from RNA viruses. Through its role as a nucleoside analog, it adeptly disrupts viral RNA research and development, thereby impeding viral replication. Synonyms: Zebularine; 1-β-D-xylofuranosyl-1H-pyrimidin-2-one; 1-((2R,3R,4R,5R)-3,4-Dihydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-1H-pyrimidin-2-one; 1-(β-D-Xylofuranosyl)-2(1H)-pyrimidinone; 1-[(2R,3R,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one. Grades: ≥95%. CAS No. 63527-47-9. Molecular formula: C9H12N2O5. Mole weight: 228.20.
5-Fluoropyrimidin-2-One beta-Ribofuranoside
5-Fluoropyrimidin-2-One beta-Ribofuranoside is an antiviral compound with applications in the research of diverse ailments, encompassing specific cancers and viral afflictions. By impeding crucial DNA research and development and replication processes, this pharmaceutical compound thwarts cancer cell propagation and viral replication. Synonyms: 1beta-D-Ribofuranosyl-5-fluoropyrimidin-2(1H)-one; 5-fluorozebularine; 5-F-Zebularine; 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-fluoropyrimidin-2-one; 5-Fluoro-zebularine; 5-Fpor; 1-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-fluoropyrimidin-2(1H)-one; 5-Fluoropyrimidin-2-one riboside; 5-Fluoropyrimidin-2-one ribonucleoside; 5-fluoropyrimidin-2-one-ribonucleoside; NSC 318509; 2(1H)-Pyrimidinone, 5-fluoro-1-beta-D-ribofuranosyl-. CAS No. 64967-16-4. Molecular formula: C9H11FN2O5. Mole weight: 246.19.
N4-Methylcytidine
N4-Methylcytidine (Nsc518744) is a cytidine nucleoside analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420), and have potential anti-metabolic and anti-tumor activities [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 10578-79-7. Pack Sizes: 10 mM * 1 mL; 25 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-W130466.
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