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| Product | Description | |
|---|---|---|
| Zileuton sodium | Zileuton sodium (A 64077 sodium) is a potent and selective inhibitor of 5-lipoxygenase , exhibiting inflammatory activities. Uses: Scientific research. Group: Signaling pathways. Alternative Names: A 64077 sodium; Abbott 64077 sodium. CAS No. 118569-21-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14164A. |  |
| Zileuton sodium | Zileuton sodium is an inhibitor of 5-lipoxygenase, and thus inhibits leukotrienes(LTB4, LTC4, LTD4 and LTE4) formation with an IC50 value of 0.5μM. Zileuton sodium has been reported to concentration-dependently inhibit the 5-lipoxygenase activity with an IC50 value of 0.5μM in RBL-1cell lysate. In addition, Zileuton sodium has been found to be a potent inhibitor of LTB formation with an IC50 value of 0.6μM. Furthermore, stimulated with A23187, Zileuton sodium has shown a dose-dependent reduction in LTB4 and 5-HETE generation in rat leukocyte with IC50 values of 0.38μM and 0.31μM, respectively. About 40-fold higher concentrations of Zileuton sodium also reduced the production of PGE2 with a IC50 of 16μM. Synonyms: Zyflo sodium. Grades: >98%. CAS No. 118569-21-4. Molecular formula: C11H11N2NaO2S. Mole weight: 258.27. |  |
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