A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Vorinostat (SAHA) is a potent and orally active pan-inhibitor of HDAC1 , HDAC2 and HDAC3 (Class I) , HDAC6 and HDAC7 (Class II) and HDAC11 (Class IV) , with ID 50 values of 10 nM and 20 nM for HDAC1 and HDAC3, respectively. Vorinostat induces cell apoptosis [1] [4]. Vorinostat is also an effective inhibitor of human papillomaviruse (HPV)-18 DNA amplification [7]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SAHA; Suberoylanilide hydroxamic acid. CAS No. 149647-78-9. Pack Sizes: 10 mM * 1 mL; 250 mg; 500 mg; 1 g; 5 g. Product ID: HY-10221.
Vorinostat
Vorinostat (suberoylanilide hydroxamic acid, SAHA) is an HDAC inhibitor with IC50 of ~10 nM. Uses: Antineoplastic agents; histone deacetylase inhibitors. Synonyms: MK-0683, MK 0683, MK0683, SAHA, M344, CCRIS 8456, HSDB 7930, Vorinostat, suberoylanilide hydroxamic acid, Zolinza. Grades: >98%. CAS No. 149647-78-9. Molecular formula: C14H20N2O3. Mole weight: 264.3.
One of the impurities of Vorinostat, which is a HDAC inhibitor and has been found to exhibit anti-angiogenic activity and could induce differentiation in breast cancer cells. Molecular formula: C14H20N2O2. Mole weight: 248.33.
Vorinostat Amination Derivative
One of the impurities of Vorinostat, which is a HDAC inhibitor and has been found to exhibit anti-angiogenic activity and could induce differentiation in breast cancer cells. Synonyms: p-Aminomethyl Vorinostat; N1-[4-(Aminomethyl)phenyl]-N8-hydroxy-octanediamide. CAS No. 1160823-16-4. Molecular formula: C15H23N3O3. Mole weight: 293.37.
Vorinostat Dimer Impurity
One of the impurities of Vorinostat, which is a HDAC inhibitor and has been found to exhibit anti-angiogenic activity and could induce differentiation in breast cancer cells. Molecular formula: C28H38N4O6. Mole weight: 526.64.
Vorinostat Impurity
One of the impurities of Vorinostat, which is a HDAC inhibitor and has been found to exhibit anti-angiogenic activity and could induce differentiation in breast cancer cells. Synonyms: N-Hydroxy-N,N-di-(N'-Phenyl-Octanediamide)amine. Molecular formula: C28H37N3O5. Mole weight: 495.62.
Vorinostat Impurity 1
One of the impurities of Vorinostat, which is a HDAC inhibitor and has been found to exhibit anti-angiogenic activity and could induce differentiation in breast cancer cells. CAS No. 866824-87-5. Molecular formula: C28H37N3O5. Mole weight: 495.62.
Vorinostat Impurity 2
One of the impurities of Vorinostat, which is a HDAC inhibitor and has been found to exhibit anti-angiogenic activity and could induce differentiation in breast cancer cells. Molecular formula: C20H24N2O2. Mole weight: 324.43.
Vornorexant
Vornorexant (ORN-0829; TS-142) is a potent dual OX1R and OX2R antagonist with IC50 values of 1.05 nM and 1.27 nM, respectively. Vornorexant exhibits potent sleep-promoting effects in vivo and can be used for insomnia research research. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ORN-0829; TS-142. CAS No. 1517965-94-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-139559.
Vornorexant
Vornorexant is a new and powerful dual orexin 1/2 receptor (OX1/2R) antagonist for the treatment of insomnia. Synonyms: (-)-[2-[[3-(5-Fluoropyridin-2-yl)-1H-pyrazol-1-yl]methyl]-1,3-oxazinan-3-yl][5-methyl-2-(2H-1,2,3-triazol-2-yl)phenyl]methanone. Grades: >98%. CAS No. 2265899-49-6. Molecular formula: C23H22FN7O2. Mole weight: 447.5.
Vorolanib
Vorolanib (CM082) is an orally active, potent multikinase VEGFR/PDGFR inhibitor. Vorolanib is a potent ATP-binding cassette (ABC) transporter inhibitor. Vorolanib is an angiogenesis inhibitor and has antitumor activity combined with ZD1839 (HY-50895) [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CM082; X-82. CAS No. 1013920-15-4. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-109019.
Vortioxetine
Vortioxetine (Lu AA21004) is a multimodal serotonergic agent, inhibits 5-HT1A, 5-HT1B, 5-HT3A, 5-HT7 receptor and SERT with IC50 of 15 nM, 33 nM, 3.7 nM, 19 nM and 1.6 nM, respectively. Uses: For research used only. Synonyms: Lu AA 21004; Lu AA21004. Grades: 0.98. CAS No. 508233-74-7. Molecular formula: C18H22N2S. Mole weight: 298.448.
Vortioxetine
Vortioxetine (Lu AA 21004) is an antagonist of 5-HT 3A and 5-HT 7 receptors ( K i : 3.7 nM, 19 nM) and an inhibitor of serotonin transporter ( SERT ) ( K i : 1.6 nM), as well as a 5-HT 1A agonist and a partial agonist of 5-HT 1B ( K i : 15 nM, 33 nM) [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Lu AA 21004. CAS No. 508233-74-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg; 500 mg; 1 g. Product ID: HY-15414.
Vortioxetine Glucose Adduct
Vortioxetine Glucose Adduct. Uses: For analytical and research use. Group: Impurity standards. Pack Sizes: 10MG. Catalog: APS013742. Format: Neat. Shipping: Room Temperature.
Vortioxetine HBr
Vortioxetine is a multimodal serotonergic agent, inhibits 5-HT1A, 5-HT1B, 5-HT3A, 5-HT7 receptor and SERT with IC50 of 15 nM, 33 nM, 3.7 nM, 19 nM and 1.6 nM, respectively. Synonyms: Lu AA21004; LuAA21004; Lu-AA21004. Grades: >98%. CAS No. 960203-27-4. Molecular formula: C18H22N2S·HBr. Mole weight: 379.36.
Vortioxetine hydrobromide
Vortioxetine (Lu AA 21004) hydrobromide is an antagonist of 5-HT 3A and 5-HT 7 receptors (K i : 3.7 nM, 19 nM) and an inhibitor of 5-hydroxytryptamine transporter (SERT) (K i : 1.6 nM), as well as a 5-HT 1A agonist and a partial 5-HT 1B agonist (K i : 15 nM, 33 nM) [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Lu AA21004 hydrobromide. CAS No. 960203-27-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg; 500 mg; 1 g. Product ID: HY-15414A.
Vortioxetine Impurity 1
One of the impurities of Vortioxetine which is a 5-HT receptor inhibitor as well s an Serotonin transporter, has been found to be an atypical antidepressant. CAS No. 1293489-71-0. Molecular formula: C17H20N2S. Mole weight: 284.43.
Vortioxetine Impurity 10 HCl
One of the impurities of Vortioxetine which is a 5-HT receptor inhibitor as well s an Serotonin transporter, has been found to be an atypical antidepressant. Synonyms: 3-Chloro-Vortioxetine Hydrochloride. Molecular formula: C18H21ClN2S. HCl. Mole weight: 369.36.
Vortioxetine Impurity 11
One of the impurities of Vortioxetine which is a 5-HT receptor inhibitor as well s an Serotonin transporter, has been found to be an atypical antidepressant. Molecular formula: C18H22N2S. Mole weight: 298.45.
Vortioxetine Impurity 12
One of the impurities of Vortioxetine which is a 5-HT receptor inhibitor as well s an Serotonin transporter, has been found to be an atypical antidepressant. Synonyms: para-Vortioxetine; 1-[4-[ (2, 4-Dimethylphenyl) thio]phenyl]piperazine. Molecular formula: C18H22N2S. Mole weight: 298.45.
Vortioxetine Impurity 13
One of the impurities of Vortioxetine which is a 5-HT receptor inhibitor as well s an Serotonin transporter, has been found to be an atypical antidepressant. Synonyms: 1-(2-BROMOPHENYL)PIPERAZINE. CAS No. 1011-13-8. Molecular formula: C10H13BrN2. Mole weight: 241.13.
Vortioxetine Impurity 14
One of the impurities of Vortioxetine which is a 5-HT receptor inhibitor as well s an Serotonin transporter, has been found to be an atypical antidepressant. CAS No. 1240670-85-2. Molecular formula: C28H34N4S. Mole weight: 458.67.
Vortioxetine Impurity 14
Vortioxetine Impurity 14. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1240670-85-2. Molecular formula: C28H34N4S. Mole weight: 458.67. Catalog: APB1240670852.
Vortioxetine Impurity 15
One of the impurities of Vortioxetine which is a 5-HT receptor inhibitor as well s an Serotonin transporter, has been found to be an atypical antidepressant. Molecular formula: C28H34N4S2. Mole weight: 490.74.
Vortioxetine Impurity 16
One of the impurities of Vortioxetine which is a 5-HT receptor inhibitor as well s an Serotonin transporter, has been found to be an atypical antidepressant. Synonyms: DIMETHYLDIPHENYLSULFIDE. CAS No. 16704-47-5. Molecular formula: C14H14S. Mole weight: 214.33.
Vortioxetine Impurity 16
Vortioxetine Impurity 16. Uses: For analytical and research use. Group: Impurity standards. CAS No. 16704-47-5. Molecular formula: C14H14S. Mole weight: 214.33. Catalog: APB16704475.
Vortioxetine Impurity 17
One of the impurities of Vortioxetine which is a 5-HT receptor inhibitor as well s an Serotonin transporter, has been found to be an atypical antidepressant. Molecular formula: C22H22S2. Mole weight: 350.55.
Vortioxetine Impurity 18
One of the impurities of Vortioxetine which is a 5-HT receptor inhibitor as well s an Serotonin transporter, has been found to be an atypical antidepressant. Synonyms: Disulfide,bis(2,4-dimethylphenyl). CAS No. 13616-83-6. Molecular formula: C16H18S2. Mole weight: 274.45.
Vortioxetine Impurity 19
One of the impurities of Vortioxetine which is a 5-HT receptor inhibitor as well s an Serotonin transporter, has been found to be an atypical antidepressant. Synonyms: 1-[2-[(2,4-diMethylphenyl)sulfinyl]phenyl]- Piperazine. CAS No. 1429908-35-9. Molecular formula: C18H22N2OS. Mole weight: 314.45.
Vortioxetine Impurity 2
One of the impurities of Vortioxetine which is a 5-HT receptor inhibitor as well s an Serotonin transporter, has been found to be an atypical antidepressant. CAS No. 1293489-69-6. Molecular formula: C17H20N2S. Mole weight: 284.43.
Vortioxetine Impurity 20
One of the impurities of Vortioxetine which is a 5-HT receptor inhibitor as well s an Serotonin transporter, has been found to be an atypical antidepressant. Synonyms: 1,2-Bis(piperazin-1-yl)benzene. CAS No. 1446750-99-7. Molecular formula: C14H22N4. Mole weight: 246.36.
Vortioxetine Impurity 21
One of the impurities of Vortioxetine which is a 5-HT receptor inhibitor as well s an Serotonin transporter, has been found to be an atypical antidepressant. Molecular formula: C33H36N2S. Mole weight: 492.73.
Vortioxetine Impurity 22
One of the impurities of Vortioxetine which is a 5-HT receptor inhibitor as well s an Serotonin transporter, has been found to be an atypical antidepressant. Molecular formula: C32H34N2S2. Mole weight: 510.77.
Vortioxetine Impurity 23
One of the impurities of Vortioxetine which is a 5-HT receptor inhibitor as well s an Serotonin transporter, has been found to be an atypical antidepressant. Molecular formula: C24H26N2S2. Mole weight: 406.62.
Vortioxetine Impurity 24
One of the impurities of Vortioxetine which is a 5-HT receptor inhibitor as well s an Serotonin transporter, has been found to be an atypical antidepressant. Molecular formula: C19H22N2OS. Mole weight: 326.46.
Vortioxetine Impurity 25
One of the impurities of Vortioxetine which is a 5-HT receptor inhibitor as well s an Serotonin transporter, has been found to be an atypical antidepressant. Molecular formula: C18H22N2O2S. Mole weight: 330.45.
Vortioxetine Impurity 26
One of the impurities of Vortioxetine which is a 5-HT receptor inhibitor as well s an Serotonin transporter, has been found to be an atypical antidepressant. Molecular formula: C24H26N2S2. Mole weight: 406.62.
Vortioxetine Impurity 29
Vortioxetine Impurity 29. Uses: For analytical and research use. Group: Impurity standards. CAS No. 10468-16-3. Molecular formula: C6H6ClNO. Mole weight: 143.57. Catalog: APB10468163.
Vortioxetine Impurity 3
One of the impurities of Vortioxetine which is a 5-HT receptor inhibitor as well s an Serotonin transporter, has been found to be an atypical antidepressant. Synonyms: CHEMBL2205045; SCHEMBL546684; CHEMBL2220208; BDBM50400880; 1-(2-(p-Tolylthio)phenyl)piperazine; 508233-82-7. CAS No. 508233-82-7. Molecular formula: C17H20N2S. Mole weight: 284.43.
Vortioxetine Impurity 33
Vortioxetine Impurity 33. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1019453-85-0. Molecular formula: C14H15NS. Mole weight: 229.34. Catalog: APB1019453850.
Vortioxetine Impurity 4
One of the impurities of Vortioxetine which is a 5-HT receptor inhibitor as well s an Serotonin transporter, has been found to be an atypical antidepressant. Synonyms: 4-Desmethyl 3-Methyl Vortioxetine; 1-[2-[(2,3-dimethylphenyl)thio]phenyl]-piperazine. CAS No. 1293489-77-6. Molecular formula: C18H22N2S. Mole weight: 298.45.
Vortioxetine Impurity 5
One of the impurities of Vortioxetine which is a 5-HT receptor inhibitor as well s an Serotonin transporter, has been found to be an atypical antidepressant. Synonyms: 4-Desmethyl 6-Methyl Vortioxetine; 1-[2-[ (2, 6-Dimethylphenyl) thio]phenyl]piperazine. Molecular formula: C18H22N2S. Mole weight: 298.45.
Vortioxetine Impurity 59
Vortioxetine Impurity 59. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1025895-66-2. Molecular formula: C17H19NS. Mole weight: 269.41. Catalog: APB1025895662.
Vortioxetine Impurity 6
One of the impurities of Vortioxetine which is a 5-HT receptor inhibitor as well s an Serotonin transporter, has been found to be an atypical antidepressant. CAS No. 1293489-74-3. Molecular formula: C18H22N2S. Mole weight: 298.45.
Vortioxetine Impurity 61
Vortioxetine Impurity 61. Uses: For analytical and research use. Group: Impurity standards. CAS No. 107832-66-6. Molecular formula: C10H14S. Mole weight: 166.28. Catalog: APB107832666.
Vortioxetine Impurity 7
One of the impurities of Vortioxetine which is a 5-HT receptor inhibitor as well s an Serotonin transporter, has been found to be an atypical antidepressant. Molecular formula: C18H22N2S. Mole weight: 298.45.
Vortioxetine Impurity 8
One of the impurities of Vortioxetine which is a 5-HT receptor inhibitor as well s an Serotonin transporter, has been found to be an atypical antidepressant. Synonyms: 4-Desmethyl 5-Methyl Vortioxetine; 1-[2-[(2,5-dimethylphenyl)thio]phenyl]-piperazine. Molecular formula: C18H22N2S. Mole weight: 298.45.
Vortioxetine Impurity 9 HCl
One of the impurities of Vortioxetine which is a 5-HT receptor inhibitor as well s an Serotonin transporter, has been found to be an atypical antidepressant. Synonyms: 5-Chloro-Vortioxetine Hydrochloride. Molecular formula: C18H21ClN2S. HCl. Mole weight: 369.36.
Vortioxetine Lactose Adduct
Vortioxetine Lactose Adduct. Uses: For analytical and research use. Group: Impurity standards. Catalog: APS003497. Format: Neat.
Vortioxetine Sulfoxide
One of the impurities of Vortioxetine which is a 5-HT receptor inhibitor as well s an Serotonin transporter, has been found to be an atypical antidepressant. Synonyms: 1-[2-[(2,4-Dimethylphenyl)sulfinyl]phenyl]-piperazine. Molecular formula: C18H22N2OS. Mole weight: 314.45.
Voruciclib
Voruciclib is an orally active and selective CDK inhibitor with K i values of 0.626 nM-9.1 nM. Voruciclib potently blocks CDK9, the transcriptional regulator of MCL-1. Voruciclib represses expression of MCL-1 in multiple models of diffuse large B-cell lymphoma (DLBCL) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1000023-04-0. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg. Product ID: HY-12422.
Voruciclib
Voruciclib is a flavone and cyclin dependent kinase (CDK) inhibitor with potential antineoplastic activity. Synonyms: Voruciclib; UNII-W66XP666AM; P1446A05, P1446A-05, P1446A 05. CAS No. 1000023-04-0. Molecular formula: C22H19ClF3NO5. Mole weight: 469.83.
Voruciclib hydrochloride
Voruciclib hydrochloride is an orally active and selective CDK inhibitor with K i values of 0.626 nM-9.1 nM. Voruciclib hydrochloride potently blocks CDK9, the transcriptional regulator of MCL-1. Voruciclib hydrochloride represses expression of MCL-1 in multiple models of diffuse large B-cell lymphoma (DLBCL) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1000023-05-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-12422A.
Vosoritide is a medicine used to treat achondroplasia. Grades: ≥95%. CAS No. 1480724-61-5. Molecular formula: C176H290N56O51S3. Mole weight: 4103.
Voxelotor
Voxelotor (GBT 440) is a potent inhibitor of haemoglobin S (HbS) polymerization. Voxelotor has the potential for sickle cell disease (SCD) treatment [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GBT 440. CAS No. 1446321-46-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-18681.
Voxilaprevir
Voxilaprevir (GS-9857) is a noncovalent, reversible inhibitor of HCV NS3/4A protease inhibitor (PI) with pangenotypic antiviral activity [1]. Voxilaprevir inhibits genotype 1b and 3a wild-type NS3 proteases with K i values of 0.038 nM and 0.066 nM, respectively [1]. Voxilaprevir is an orally active direct-acting antiviral agent ( DAA ) and can be used for HCV infection research [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GS-9857. CAS No. 1535212-07-7. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-19840.
Voxtalisib (XL-765)
Cas No. 934493-76-2.
VP11 Reagent
10ml Pack Size. Group: Analytical Reagents, Biochemicals, Diagnostic Raw Materials. Formula: KOH ,C4H9N3O2 , H2O. Prepack ID 90004975-10ml. See USA prepack pricing.
VP 14637
Human respiratory syncytial virus (HRSV) is a major respiratory viral pathogen causing moderate to severe upper and lower respiratory tract infections in all ages and across a wide range of patient populations. Group: Biochemicals. Alternative Names: 2, 2'-[ (4-Hydroxyphenyl) methylene]bis[4-[[ (5-methyl-1H-tetrazol-1-yl) imino]methyl]phenol. Grades: Highly Purified. CAS No. 235106-62-4. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
VP-14637
VP-14637 is a small molecule inhibitor of respiratory syncytial virus (RSV) with EC50 value of 1.4 nM. It suppresses RSV via binding to the viral F protein and inhibiting the RSV fusion (EC50 = 5.4 nM). Synonyms: VP 14637; VP14637; 2-[[2-Hydroxy-5-[(E)-(5-methyltetrazol-1-yl)iminomethyl]phenyl]-(4-hydroxyphenyl)methyl]-4-[(E)-(5-methyltetrazol-1-yl)iminomethyl]phenol. Grades: ≥98%. CAS No. 235106-62-4. Molecular formula: C25H22N10O3. Mole weight: 510.5.
VP16 (411-490), GST tagged from human herpesvirus 2
recombinant, expressed in E. coli, ?80% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy.
VP1 Reagent
10ml Pack Size. Group: Analytical Reagents, Biochemicals, Diagnostic Raw Materials. Formula: CH3CH2OH ,C10H8O , H2O. Prepack ID 90005085-10ml. See USA prepack pricing.
VP-22
VP-22 peptide is from herpes simplex virus type-1. Synonyms: H-Asp-Ala-Ala-Thr-Ala-Thr-Arg-Gly-Arg-Ser-Ala-Ala-Ser-Arg-Pro-Thr-Glu-Arg-Pro-Arg-Ala-Pro-Ala-Arg-Ser-Ala-Ser-Arg-Pro-Arg-Arg-Pro-Val-Asp-OH; HSV-1 protein VP22. Grades: >98%. Molecular formula: C147H255N61O48. Mole weight: 3645.02.
VPA-985
VPA-985, an azepine compound, has been found to be a Vasopressin receptor antagonist that could be used in some cardiovascular disease therapy like hyponatraemia. Uses: Drug used in the treatment and prevention of cardiovascular diseases. Synonyms: CRTX-080; CRTX080; CRTX 080; VPA-985; VPA985; VPA 985; WAY-VPA-985; Lixivaptan; N-[3-Chloro-4-(5H-pyrrolo[2,1-c][1,4]benzodiazepin-10(11H)-ylcarbonyl)phenyl]-5-fluoro-2-methylbenzamide;Lixivaptan; VPA-985. Grades: 98%. CAS No. 168079-32-1. Molecular formula: C27H21ClFN3O2. Mole weight: 473.94.
VPC 23019 is an aryl amide-containing S1P analog that acts as a competitive antagonist, inhibit S1P-induced migration of thyroid cancer cells, ovarian cancer cells, and neural stem cells. Uses: Sphingosine-1-phosphate receptor antagonist. Synonyms: VPC23019; VPC-23019; (R)-phosphoric acid mono-[2-amino-2-(3-octyl-phenylcarbamoyl)-ethyl] ester. Grades: ≥98%. CAS No. 449173-19-7. Molecular formula: C17H29N2O5P. Mole weight: 372.40.
VPC 23019
VPC 23019. Group: Biochemicals. Grades: Purified. CAS No. 449173-19-7. Pack Sizes: 10mg. US Biological Life Sciences.