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| Product | Description | |
|---|---|---|
| Vortioxetine Impurity 2 | One of the impurities of Vortioxetine which is a 5-HT receptor inhibitor as well s an Serotonin transporter, has been found to be an atypical antidepressant. CAS No. 1293489-69-6. Molecular formula: C17H20N2S. Mole weight: 284.43. |  |
| Vortioxetine Impurity 20 | One of the impurities of Vortioxetine which is a 5-HT receptor inhibitor as well s an Serotonin transporter, has been found to be an atypical antidepressant. Synonyms: 1,2-Bis(piperazin-1-yl)benzene. CAS No. 1446750-99-7. Molecular formula: C14H22N4. Mole weight: 246.36. | |
| Vortioxetine Impurity 21 | One of the impurities of Vortioxetine which is a 5-HT receptor inhibitor as well s an Serotonin transporter, has been found to be an atypical antidepressant. Molecular formula: C33H36N2S. Mole weight: 492.73. | |
| Vortioxetine Impurity 22 | One of the impurities of Vortioxetine which is a 5-HT receptor inhibitor as well s an Serotonin transporter, has been found to be an atypical antidepressant. Molecular formula: C32H34N2S2. Mole weight: 510.77. | |
| Vortioxetine Impurity 23 | One of the impurities of Vortioxetine which is a 5-HT receptor inhibitor as well s an Serotonin transporter, has been found to be an atypical antidepressant. Molecular formula: C24H26N2S2. Mole weight: 406.62. | |
| Vortioxetine Impurity 24 | One of the impurities of Vortioxetine which is a 5-HT receptor inhibitor as well s an Serotonin transporter, has been found to be an atypical antidepressant. Molecular formula: C19H22N2OS. Mole weight: 326.46. | |
| Vortioxetine Impurity 25 | One of the impurities of Vortioxetine which is a 5-HT receptor inhibitor as well s an Serotonin transporter, has been found to be an atypical antidepressant. Molecular formula: C18H22N2O2S. Mole weight: 330.45. | |
| Vortioxetine Impurity 26 | One of the impurities of Vortioxetine which is a 5-HT receptor inhibitor as well s an Serotonin transporter, has been found to be an atypical antidepressant. Molecular formula: C24H26N2S2. Mole weight: 406.62. | |
| Vortioxetine Impurity 29 | Vortioxetine Impurity 29. Uses: For analytical and research use. Group: Impurity standards. CAS No. 10468-16-3. Molecular formula: C6H6ClNO. Mole weight: 143.57. Catalog: APB10468163. |  |
| Vortioxetine Impurity 3 | One of the impurities of Vortioxetine which is a 5-HT receptor inhibitor as well s an Serotonin transporter, has been found to be an atypical antidepressant. Synonyms: CHEMBL2205045; SCHEMBL546684; CHEMBL2220208; BDBM50400880; 1-(2-(p-Tolylthio)phenyl)piperazine; 508233-82-7. CAS No. 508233-82-7. Molecular formula: C17H20N2S. Mole weight: 284.43. | |
| Vortioxetine Impurity 33 | Vortioxetine Impurity 33. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1019453-85-0. Molecular formula: C14H15NS. Mole weight: 229.34. Catalog: APB1019453850. | |
| Vortioxetine Impurity 4 | One of the impurities of Vortioxetine which is a 5-HT receptor inhibitor as well s an Serotonin transporter, has been found to be an atypical antidepressant. Synonyms: 4-Desmethyl 3-Methyl Vortioxetine; 1-[2-[(2,3-dimethylphenyl)thio]phenyl]-piperazine. CAS No. 1293489-77-6. Molecular formula: C18H22N2S. Mole weight: 298.45. | |
| Vortioxetine Impurity 5 | One of the impurities of Vortioxetine which is a 5-HT receptor inhibitor as well s an Serotonin transporter, has been found to be an atypical antidepressant. Synonyms: 4-Desmethyl 6-Methyl Vortioxetine; 1-[2-[ (2, 6-Dimethylphenyl) thio]phenyl]piperazine. Molecular formula: C18H22N2S. Mole weight: 298.45. | |
| Vortioxetine Impurity 59 | Vortioxetine Impurity 59. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1025895-66-2. Molecular formula: C17H19NS. Mole weight: 269.41. Catalog: APB1025895662. | |
| Vortioxetine Impurity 6 | One of the impurities of Vortioxetine which is a 5-HT receptor inhibitor as well s an Serotonin transporter, has been found to be an atypical antidepressant. CAS No. 1293489-74-3. Molecular formula: C18H22N2S. Mole weight: 298.45. | |
| Vortioxetine Impurity 61 | Vortioxetine Impurity 61. Uses: For analytical and research use. Group: Impurity standards. CAS No. 107832-66-6. Molecular formula: C10H14S. Mole weight: 166.28. Catalog: APB107832666. | |
| Vortioxetine Impurity 7 | One of the impurities of Vortioxetine which is a 5-HT receptor inhibitor as well s an Serotonin transporter, has been found to be an atypical antidepressant. Molecular formula: C18H22N2S. Mole weight: 298.45. | |
| Vortioxetine Impurity 8 | One of the impurities of Vortioxetine which is a 5-HT receptor inhibitor as well s an Serotonin transporter, has been found to be an atypical antidepressant. Synonyms: 4-Desmethyl 5-Methyl Vortioxetine; 1-[2-[(2,5-dimethylphenyl)thio]phenyl]-piperazine. Molecular formula: C18H22N2S. Mole weight: 298.45. | |
| Vortioxetine Impurity 9 HCl | One of the impurities of Vortioxetine which is a 5-HT receptor inhibitor as well s an Serotonin transporter, has been found to be an atypical antidepressant. Synonyms: 5-Chloro-Vortioxetine Hydrochloride. Molecular formula: C18H21ClN2S. HCl. Mole weight: 369.36. | |
| Vortioxetine Lactose Adduct | Vortioxetine Lactose Adduct. Uses: For analytical and research use. Group: Impurity standards. Catalog: APS003497. Format: Neat. | |
| Vortioxetine Sulfoxide | One of the impurities of Vortioxetine which is a 5-HT receptor inhibitor as well s an Serotonin transporter, has been found to be an atypical antidepressant. Synonyms: 1-[2-[(2,4-Dimethylphenyl)sulfinyl]phenyl]-piperazine. Molecular formula: C18H22N2OS. Mole weight: 314.45. | |
| Voruciclib | Voruciclib is an orally active and selective CDK inhibitor with K i values of 0.626 nM-9.1 nM. Voruciclib potently blocks CDK9, the transcriptional regulator of MCL-1. Voruciclib represses expression of MCL-1 in multiple models of diffuse large B-cell lymphoma (DLBCL) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1000023-04-0. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg. Product ID: HY-12422. |  |
| Voruciclib | Voruciclib is a flavone and cyclin dependent kinase (CDK) inhibitor with potential antineoplastic activity. Synonyms: Voruciclib; UNII-W66XP666AM; P1446A05, P1446A-05, P1446A 05. CAS No. 1000023-04-0. Molecular formula: C22H19ClF3NO5. Mole weight: 469.83. | |
| Voruciclib hydrochloride | Voruciclib hydrochloride is an orally active and selective CDK inhibitor with K i values of 0.626 nM-9.1 nM. Voruciclib hydrochloride potently blocks CDK9, the transcriptional regulator of MCL-1. Voruciclib hydrochloride represses expression of MCL-1 in multiple models of diffuse large B-cell lymphoma (DLBCL) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1000023-05-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-12422A. | |
| Vosaroxin hydrochloride | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| Vosilasarm | Vosilasarm (RAD140) is a potent, orally active, nonsteroidal selective androgen receptor modulator (SARM) with a Ki of 7 nM. Vosilasarm shows good selectivity over other steroid hormone nuclear receptors[1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: RAD140; EP0062. CAS No. 1182367-47-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-14383. | |
| Vosoritide | Vosoritide is a medicine used to treat achondroplasia. Grades: ≥95%. CAS No. 1480724-61-5. Molecular formula: C176H290N56O51S3. Mole weight: 4103. | |
| Vosoritide acetate | Vosoritide (BMN 111) acetate is a natriuretic peptide receptor 2 (NPR2) agonist that acts on the proliferation and differentiation of chondrocytes to promote bone growth[1]. Uses: Scientific research. Group: Peptides. Alternative Names: BMN 111 acetate. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P3503A. | |
| Votoplam | Votoplam (PTC518) (Example 37) is an HTT gene regulator with an IC50 ? 0.1 ?M. Votoplam can be used in the research of Huntington's disease[1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PTC518. CAS No. 2407849-89-0. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-156650. | |
| Voxelotor | Voxelotor (GBT 440) is a potent inhibitor of haemoglobin S (HbS) polymerization. Voxelotor has the potential for sickle cell disease (SCD) treatment [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GBT 440. CAS No. 1446321-46-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-18681. | |
| Voxilaprevir | Voxilaprevir (GS-9857) is a noncovalent, reversible inhibitor of HCV NS3/4A protease inhibitor (PI) with pangenotypic antiviral activity [1]. Voxilaprevir inhibits genotype 1b and 3a wild-type NS3 proteases with K i values of 0.038 nM and 0.066 nM, respectively [1]. Voxilaprevir is an orally active direct-acting antiviral agent ( DAA ) and can be used for HCV infection research [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GS-9857. CAS No. 1535212-07-7. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-19840. | |
| Voxtalisib | Voxtalisib (XL765) is a potent PI3K inhibitor, which has a similar activity toward class I PI3K (IC50s=39, 113, 9 and 43?nM for p110?, p110?, p110? and p110?, respectively), also inhibits DNA-PK (IC50=150?nM) and mTOR (IC50=157?nM). Voxtalisib (XL765) inhibits mTORC1 and mTORC2 with IC50s of 160 and 910 nM, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: XL765; SAR245409. CAS No. 934493-76-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15900. | |
| Voxtalisib (XL-765) | Cas No. 934493-76-2. | |
| VP11 Reagent | 10ml Pack Size. Group: Analytical Reagents, Biochemicals, Diagnostic Raw Materials. Formula: KOH ,C4H9N3O2 , H2O. Prepack ID 90004975-10ml. See USA prepack pricing. |  |
| VP 14637 | Human respiratory syncytial virus (HRSV) is a major respiratory viral pathogen causing moderate to severe upper and lower respiratory tract infections in all ages and across a wide range of patient populations. Group: Biochemicals. Alternative Names: 2, 2'-[ (4-Hydroxyphenyl) methylene]bis[4-[[ (5-methyl-1H-tetrazol-1-yl) imino]methyl]phenol. Grades: Highly Purified. CAS No. 235106-62-4. Pack Sizes: 10mg. US Biological Life Sciences. |  Worldwide |
| VP-14637 | VP-14637 is a small molecule inhibitor of respiratory syncytial virus (RSV) with EC50 value of 1.4 nM. It suppresses RSV via binding to the viral F protein and inhibiting the RSV fusion (EC50 = 5.4 nM). Synonyms: VP 14637; VP14637; 2-[[2-Hydroxy-5-[(E)-(5-methyltetrazol-1-yl)iminomethyl]phenyl]-(4-hydroxyphenyl)methyl]-4-[(E)-(5-methyltetrazol-1-yl)iminomethyl]phenol. Grades: ≥98%. CAS No. 235106-62-4. Molecular formula: C25H22N10O3. Mole weight: 510.5. | |
| VP16 (411-490), GST tagged from human herpesvirus 2 | recombinant, expressed in E. coli, ?80% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| VP1 Reagent | 10ml Pack Size. Group: Analytical Reagents, Biochemicals, Diagnostic Raw Materials. Formula: CH3CH2OH ,C10H8O , H2O. Prepack ID 90005085-10ml. See USA prepack pricing. | |
| VP-22 | VP-22 peptide is from herpes simplex virus type-1. Synonyms: H-Asp-Ala-Ala-Thr-Ala-Thr-Arg-Gly-Arg-Ser-Ala-Ala-Ser-Arg-Pro-Thr-Glu-Arg-Pro-Arg-Ala-Pro-Ala-Arg-Ser-Ala-Ser-Arg-Pro-Arg-Arg-Pro-Val-Asp-OH; HSV-1 protein VP22. Grades: >98%. Molecular formula: C147H255N61O48. Mole weight: 3645.02. | |
| VPA-985 | VPA-985, an azepine compound, has been found to be a Vasopressin receptor antagonist that could be used in some cardiovascular disease therapy like hyponatraemia. Uses: Drug used in the treatment and prevention of cardiovascular diseases. Synonyms: CRTX-080; CRTX080; CRTX 080; VPA-985; VPA985; VPA 985; WAY-VPA-985; Lixivaptan; N-[3-Chloro-4-(5H-pyrrolo[2,1-c][1,4]benzodiazepin-10(11H)-ylcarbonyl)phenyl]-5-fluoro-2-methylbenzamide;Lixivaptan; VPA-985. Grades: 98%. CAS No. 168079-32-1. Molecular formula: C27H21ClFN3O2. Mole weight: 473.94. | |
| VPC 01091 | VPC 01091. Group: Others. Purity: >99%. Mole weight: 339.943. Stability: 6 Months. Storage: -20°C. Avanti Polar Lipids; lipid products; bioactive lipids; fluorescent lipids; singnal transduction; cell pathways; VPC 01091; ((1R,3S)-1-amino-3-(3-octylphenyl)cyclopentyl)methanol (hydrochloride salt). Cat No: FLBZ-104. |  |
| VPC01091.4 | VPC01091.4 (VPC4) is a TRPM7 inhibitor and blocks TRPM7 current at low micromolar concentrations. VPC01091.4 is an efficacious anti-inflammatory agent that arrests systemic inflammation in vivo[1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: VPC4. CAS No. 945604-76-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-157227. | |
| VPC 01211 | VPC 01211. Group: Others. Purity: >99%. Mole weight: 383.462. Stability: 6 Months. Storage: -20°C. Avanti Polar Lipids; lipid products; bioactive lipids; fluorescent lipids; singnal transduction; cell pathways; VPC 01211; ((1R,3S)-1-ammonio-3-(4-octylphenyl)cyclopentyl)methyl hydrogen phosphate. Cat No: FLBZ-093. | |
| VPC 23019 | VPC 23019 is an aryl amide-containing S1P analog that acts as a competitive antagonist, inhibit S1P-induced migration of thyroid cancer cells, ovarian cancer cells, and neural stem cells. Uses: Sphingosine-1-phosphate receptor antagonist. Synonyms: VPC23019; VPC-23019; (R)-phosphoric acid mono-[2-amino-2-(3-octyl-phenylcarbamoyl)-ethyl] ester. Grades: ≥98%. CAS No. 449173-19-7. Molecular formula: C17H29N2O5P. Mole weight: 372.40. | |
| VPC 23019 | VPC 23019. Group: Biochemicals. Grades: Purified. CAS No. 449173-19-7. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| VPC 51299 | VPC 51299. Group: Others. Purity: >99%. Mole weight: 670.74. Stability: 6 Months. Storage: -20°C. Avanti Polar Lipids; lipid products; bioactive lipids; fluorescent lipids; singnal transduction; cell pathways; VPC 51299; (R,E)-(3-palmitamido-4-(4-((4-(2,2,2-trifluoroethoxy)pyriDin-2-yl)methoxy)phenyl)but-1-en-1-yl)phosphonic acid. Cat No: FLBZ-019. | |
| VPC-70063 | VPC-70063 is a Myc-Max inhibitor. VPC-70067 is a close analog of the previously identified Myc inhibitor 10058-F4. VPC-70063, of a chemically different scaffold, was the best performer in a panel of in vitro assays, and the forerunner for future hit-to-lead optimization efforts. Uses: Designed for use in research and industrial production. Additional or Alternative Names: VPC-70063; VPC 70063; VPC70063. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 13571-44-3. Molecular formula: C16H12F6N2S. Mole weight: 378.34. Purity: >98%. IUPACName: N-[3,5-Bis(trifluoromethyl)phenyl]-N'-(phenylmethyl)thiourea. Canonical SMILES: S=C(NCC1=CC=CC=C1)NC2=CC(C(F)(F)F)=CC(C(F)(F)F)=C2. Product ID: ACM13571443. Alfa Chemistry ISO 9001:2015 Certified. |  |
| vp/eicosene copolymer | vp/eicosene copolymer. Group: Polymers. CAS No. 28211-18-9. Product ID: 1-ethenylpyrrolidin-2-one; icos-1-ene. Molecular formula: 391.7g/mol. Mole weight: C26H49NO. CCCCCCCCCCCCCCCCCCC=C.C=CN1CCCC1=O. InChI= 1S / C20H40. C6H9NO / c1-3-5-7-9-11-13-15-17-19-20-18-16-14 -12-10-8-6-4-2; 1-2-7-5-3-4-6 (7) 8 / h3H, 1, 4-20H2, 2H3; 2H, 1, 3-5H2. HTLWOXWXUHOLEJ-UHFFFAOYSA-N. |  |
| VPM peptide | VPM peptide is a dithiol protease-cleavable peptide cross-linker. VPM peptide can be incorporated into the backbone of the PEG-diacrylate (PEG-DA) macromer to form PEG hydrogel [1] [2]. Uses: Scientific research. Group: Peptides. CAS No. 1428885-83-9. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P3159. | |
| VPS34 human | recombinant, expressed in Sf9 cells. Group: Fluorescence/luminescence spectroscopy. | |
| Vps34-IN-1 | Vps34-IN-1 is a potent and selective inhibitor of class III Vps34 PI3K. Vps34-IN-1 inhibits phosphorylation of PtdIns by recombinant insect cell expressed Vps34-Vps15 complex with an IC50 of ~25 nM. Vps34-IN-1 can suppress SGK3 activation by reducing PtdIns(3)P levels via lowering phosphorylation of T-loop and hydrophobic motifs. Vps34-IN-1 modulates autophagy[1][2][3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1383716-33-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-12795. | |
| VPS34-IN1 | VPS34-IN1 is a potent and selective Vps34 inhibitor with potential anticancer activity. VPS34-IN1 inhibits Vps34 with 25 nM IC50 in vitro. Synonyms: VPS34IN1; VPS34 IN1; VPS34-IN1. Grades: 98%. CAS No. 1383716-33-3. Molecular formula: C21H24ClN7O. Mole weight: 425.91. | |
| VPS34 inhibitor 1 | VPS34 inhibitor 1 is a potent and selective inhibitor of VPS34 (IC50 = 15 nM). Vps34 is a phosphoinositide 3-kinase (PI3K) class III isoform that has attracted major attention over the recent years because of its role in autophagy. VPS34 inhibitors can be used to investigate autophagy, a degradation process that recycles cellular components. Synonyms: 1-[[4-(cyclopropylmethyl)-5-[2-(pyridin-4-ylamino)pyrimidin-4-yl]pyrimidin-2-yl]amino]-2-methylpropan-2-ol; Compound 19, PIK-III analogue; Compound 19, PIK-III analogue. Grades: 99.27 %. CAS No. 1383716-46-8. Molecular formula: C21H25N7O. Mole weight: 391.47. | |
| Vps34-PIK-III | Vps34-PIK-III is a potent and selective inhibitor of the type 3 phosphatidylinositol 3-kinase (PI3K) vacuolar protein sorting 34 (Vps34) (IC50 = 18 nM). Vps34-PIK-III is selective for Vps34 over related PI3K isoforms, PI4Kβ, and mTOR. Synonyms: 4-(cyclopropylmethyl)-5-[2-(pyridin-4-ylamino)pyrimidin-4-yl]pyrimidin-2-amine; PIK-III; VPS34-IN2; VPS34-IN 2; VPS34-IN-2. CAS No. 1383716-40-2. Molecular formula: C17H17N7. Mole weight: 319.36. | |
| Vps34-PIK-III | Vps34-PIK-III is an orally active and selective VPS34 inhibitor (IC50=18 nM). Vps34-PIK-III effectively inhibits autophagy and can be used as a molecular tool. vps34-PIK-III is also a PI3K inhibitor that inhibits the expression of genes in liver cancer stem cells (CSCs)[1][2][3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1383716-40-2. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12794. | |
| VR23 | VR23 is a small molecule that potently inhibits the activities of trypsin-like proteasomes (IC50=1 nM), chymotrypsin-like proteasomes (IC50=50-100 nM), and caspase-like proteasomes (IC50=3 ?M). Uses: Scientific research. Group: Signaling pathways. CAS No. 1624602-30-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-18741. | |
| VR23 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| VR23 | VR23 is a potent and selective inhibitor of trypsin-like proteasomes (IC50 = 1 nmol/L), chymotrypsin-like proteasomes (IC50 = 50-100 nmol/L), and caspase-like proteasomes (IC50 = 3 μmol/L). Synonyms: VR23; VR-23; VR 23. Grades: 98%. CAS No. 1624602-30-7. Molecular formula: C19H16ClN5O6S. Mole weight: 477.88. | |
| VrCRP | VrCRP is a peptide isolated from V. radiata (a bruchid-resistant mungbean). It has activity against bacteria and fungi. Synonyms: Arg-Thr-Cys-Met-Ile-Lys-Lys-Glu-Gly-Trp-Gly-Lys-Cys-Leu-Ile-Asp-Thr-Thr-Cys-Ala-His-Ser-Cys-Lys-Asn-Arg-Gly-Tyr-Ile-Gly-Gly-Asp-Cys-Lys-Gly-Met-Thr-Arg-Thr-Cys-Tyr-Cys-Leu-Val-Asn-Cys. Molecular formula: C211H347N65O63S10. Mole weight: 5123.07. | |
| VrD1 | VrD1 is an antimicrobial plant peptide isolated from Vigna radiata. It has activity against fungi. Synonyms: Arg-Thr-Cys-Met-Ile-Lys-Lys-Glu-Gly-Trp-Gly-Lys-Cys-Leu-Ile-Asp-Thr-Thr-Cys-Ala-His-Ser-Cys-Lys-Asn-Arg-Gly-Tyr-Ile-Gly-Gly-Asn-Cys-Lys-Gly-Met-Thr-Arg-Thr-Cys-Tyr-Cys-Leu-Val-Asn-Cys. | |
| VrD2 | VrD2 is an plant antimicrobial peptide isolated from Vigna radiata. It has activity against gram-positive bacteria, gram-negative bacteria and fungi. Synonyms: Lys-Thr-Cys-Glu-Asn-Leu-Ala-Asn-Thr-Tyr-Arg-Gly-Pro-Cys-Phe-Thr-Thr-Gly-Ser-Cys-Asp-Asp-His-Cys-Lys-Asn-Lys-Glu-His-Leu-Arg-Ser-Gly-Arg-Cys-Arg-Asp-Asp-Phe-Arg-Cys-Trp-Cys-Thr-Arg-Asn-Cys. Molecular formula: C222H347N77O72S8. Mole weight: 5503.15. | |
| VRK1, active, GST tagged human | recombinant, expressed in baculovirus infected Sf9 cells, ?70% (SDS-PAGE), buffered aqueous glycerol solution. Group: Fluorescence/luminescence spectroscopy. | |
| VRK1/CK1-IN-1 | VRK1/CK1-IN-1 (compound 36) is a dual inhibitor of vaccinia-related kinase 1 (VRK1) and casein kinase 1 (CK1), with the Ki of 37.9 nM for VRK1 and IC50s of 17 nM and 15 nM for ? and ? isoforms of CK1, respectively[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 3050772-20-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-158975. | |
| VRK2, active, GST tagged human | recombinant, expressed in baculovirus infected Sf9 cells, ?70% (SDS-PAGE), buffered aqueous glycerol solution. Group: Fluorescence/luminescence spectroscopy. | |
| VRK-IN-1 | VRK-IN-1 is a potent and selective inhibitor of vaccinia-related kinases 1 (VRK1), with an IC50 of 150 nM. VRK1 is human Ser/Thr protein kinases associated with increased cell division and neurological disorders[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2378855-09-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-126542. | |
| VRT-043198 | VRT-043198, the active metabolite of VX-765, is a Caspase inhibitor. VRT-043198 exhibits 100- to 10,000-fold selectivity against other caspase-3 and -6 to -9. VRT-043198 inhibited the release of interleukin (IL)-1beta and IL-18, but it had little effect on the release of several other cytokines, including IL-1alpha, tumor necrosis factor-alpha, IL-6 and IL-8. Synonyms: VRT043198; VRT 043198; N-(4-Amino-3-chlorobenzoyl)-3-methyl-L-valyl-N-[(1S)-2-carboxy-1-formylethyl]-L-prolinamide; (S)-3-({1-((S)-1-((S)-2-{(1-(4-Amino-3-chlorophenyl)methanoyl)amino}-3,3-dimethyl-butanoyl)pyrrolidin-2-yl)methanoyl}amino)-4-oxobutyric acid. Grades: ≥98%. CAS No. 244133-31-1. Molecular formula: C22H29ClN4O6. Mole weight: 480.94. | |
| VRT-043198 | VRT-043198, the agent metabolite of VX-765 (Belnacasan), is a potent, selective and blood-brain barrier permeable inhibitor of interleukin-converting enzyme/caspase-1 subfamily caspases. VRT-043198 exhibits Ki values of 0.8 nM and 0.6 nM for ICE/caspase-1 and caspase-4, respectively[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 244133-31-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112226. | |
| VRT-532 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| VRX-806 | VRX-806 is a novel nonnucleoside reverse transcriptase inhibitor (NNRTI) with potent in vitro activity against wild-type and NNRTI-resistant HIV-1. Synonyms: VRX-806; VRX 806; VRX806; AR-806; AR 806; AR806; RDEA-806; RDEA 806; RDEA806;4-[[2-[[5-bromo-4-(4-cyclopropylnaphthalen-1-yl)-1,2,4-triazol-3-yl]sulfanyl]acetyl]amino]-3-chlorobenzoic acid. Grades: >98 %. CAS No. 1004523-72-1. Molecular formula: C24H18BrClN4O3S. Mole weight: 557.85. | |
| VS-5584 | VS-5584 is a pan-PI3K/mTOR kinase inhibitor with IC50s of 16 nM, 68 nM, 42 nM, 25 nM, and 37 nM for PI3Kα, PI3Kβ, PI3Kδ, PI3Kγ and mTOR, respectively. VS-5584 simultaneously blocks mTORC2 as well as mTORC1. Synonyms: VS5584; VS 5584; VS5584; SB2343; SB2343; SB 2343. CAS No. 1246560-33-7. Molecular formula: C17H22N8O. Mole weight: 354.418. | |
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