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ARN14686 is a NAAA (N-acylethanolamine acid amidase) activity-based protein profiling (ABPP) probe. ARN14686 can be used to detect NAAA by using click chemistry in cell lysates or intact cells, which binds covalently to the N-terminal cysteine of catalytically active NAAA to form a thioester adduct. ARN14686 inhibits the hydrolysis of the NAAA substrate PAMCA in HEK293 cells. The IC50s for human is 6 and the IC50s for rat recombinant enzymes is 13 nM. Synonyms: (S)-Undec-10-yn-1-yl (2-oxoazetidin-3-yl)carbamate. Grades: ≥98% by HPLC. CAS No. 1628345-10-7. Molecular formula: C15H24N2O3. Mole weight: 280.36.
ARN14974
ARN14974 is a benzoxazolone carboxamide inhibitor of acid ceramidase with IC50 of 79 nM. It inhibits acid ceramidase activity, reduces levels of sphingosine and dihydroceramide, and increases levels of ceramide in SW403 adenocarcinoma cells and RAW 264.7 murine macrophages when used at concentrations ranging from 0.1 to 20 mM. Synonyms: Acid Ceramidase Inhibitor 17a; ARN-14974; ARN 14974; Acid Ceramidase Inhibitor 17a. Grades: ≥95%. CAS No. 1644158-57-5. Molecular formula: C24H21FN2O3. Mole weight: 404.4.
ARN14988
ARN14988 can normalize ceramide levels and concomitantly sensitize proliferative melanoma cells to the cytotoxic actions of various antitumoral agents. ARN14988 is a potent inhibitor of acid ceramidase with IC50 of 12.8 nM for the human enzyme. ARN14988 also reduces growth of A375 with EC50s of 41.8 μM and G361 with EC50s of 67.7 μM. Synonyms: ARN 14988; ARN-14988. Grades: ≥98%. CAS No. 1502027-70-4. Molecular formula: C16H24ClN3O5. Mole weight: 373.83.
ARN19874
ARN19874 is an inhibitor of N-acyl phosphatidylethanolamine phospholipase D (NAPE-PLD) with IC50 of 33.7 μM. ARN19874 is the first selective, cell-active inhibitor of NAPE-PLD. It is significantly less potent on the Q320A mutant, and it can cause a substantial accumulation of non-metabolized NAPE species iuman HEK-293 cells at 50 uM. Uses: Enzyme inhibitors. Synonyms: 2,4-dioxo-N-[4-(4-pyridyl)phenyl]-1H-quinazoline-6-sulfonamide. Grades: ≥98%. CAS No. 2190502-57-7. Molecular formula: C19H14N4O4S. Mole weight: 394.41.
ARN 272
ARN 272 has been found to be a FLAT inhibitor and could show analgesic activities in CB1-mediated nociceptive and inflammatory pain. Synonyms: ARN272; ARN-272; ARN 272; 4-[[4-(4-Hydroxyphenyl)-1-phthalazinyl]amino]-N-phenylbenzamide. Grades: ≥98% by HPLC. CAS No. 488793-85-7. Molecular formula: C27H20N4O2. Mole weight: 432.47.
ARN 272
ARN 272. Group: Biochemicals. Grades: Purified. CAS No. 488793-85-7. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
ARN2966
ARN2966, also called 2-PMAP, as a Amyloid-β inhibitor, is non toxic, orally absorbable, blood-brain-barrier penetrable, and effective in vitro and in vivo. Uses: Anti-alzheimer agents; amyloid-β inhibitor. Synonyms: 2-(pyridin-2-ylmethylamino)phenol; 2-PMAP; ARN2966; ARN-2966; Phenol, 2-[(2-pyridinylmethyl)amino]-; 102212-26-0; AGN-PC-0031SD; GTPL7530; 2-(2-Pyridylmethylamino)phenol; SCHEMBL10886688; AOB1080; SYN5152; 2-(pyridin-2-ylmethylamino)phenol; 3970AH; ZINC34411048; AKOS022987680; CS-3335; HY-18292; ARN-2966; CS 3335; HY 18292; ARN 2966; CS3335; HY18292; ARN2966. Grades: > 98%. CAS No. 102212-26-0. Molecular formula: C12H12N2O. Mole weight: 200.24.
ARN-3236
ARN-3236 is an oral active and selective inhibitor of salt-inducible kinase 2 (SIK2) , with IC 50 s of <1 nM, 21.63 nM and 6.63 nM for SIK2, SIK1 and SIK3, respectively. Has anti-cancer activity [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1613710-01-2. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-120856.
ARN-5187
ARN-5187, a piperazin derivative, has been found to be a REV-ERBβ inhibitor that could induce apoptotic in cancer cells and probably be more effective in breast cancer cells. Synonyms: ARN5187; ARN-5187; ARN 5187; 4- ( ( (1- (2-fluorophenyl) cyclopentyl) amino) methyl) -2- ( (4-methylpiperazin-1-yl) methyl) phenol hydrochloride. Grades: 98%. CAS No. 1700693-96-4. Molecular formula: C24H33ClFN3O. Mole weight: 434.00.
ARN726
ARN726 is a systemically active and orally bioavailable N-acylethanolamine acid amidase (NAAA) inhibitor with IC50 value of 27 nM for human and 63 nM for rat NAAA. The selectivity for NAAA is better than fatty acid amide hydrolase (FAAH) with IC50s of 100 uM. It is also selective over acid cermidase with IC5Os of 12.5 uM. ARN726 can decrease lung myeloperoxidase activity and pleural exudate TNF-α levels in a mouse model of carrageenan-induced lung inflammation. Synonyms: ARN-0726; ARN 0726. Grades: ≥95%. CAS No. 1628343-77-0. Molecular formula: C14H24N2O3. Mole weight: 268.35.
ARNAX
ARNAX is a TLR3-specific agonist that does not activate the mitochondrial antiviral-signaling protein (MAVS) pathway, and thus does not induce systemic inflammation. Synonyms: GpC ODN+MV DI RNA.
ARND'S ALLOY
ARND'S ALLOY. Uses: Designed for use in research and industrial production. Additional or Alternative Names: ARND'S ALLOY. Product Category: Heterocyclic Organic Compound. CAS No. 51636-39-6. Molecular formula: CuMg. Purity: 0.96. Product ID: ACM51636396. Alfa Chemistry ISO 9001:2015 Certified.
Arnebin 1 is found in Arnebia euchroma. Synonyms: Dmask; beta,beta-Dimethylacrylshikonin; Dimethylacrylshikonin; Isoarnebin I. Grades: > 95%. CAS No. 5162-1-6. Molecular formula: C21H22O6. Mole weight: 370.39.
Arnica Extract
Arnica Extract. Applications: Boost the blood move.anti-inflammation have effect in epilepsy , trauma and pelagism. Group: Others. Synonyms: Arnica Extract; Arnica montana. Purity: 5-10:1 By TLC. Appearance: Brown yellow fine powder. Storage: 2 years under well storage situation and stored away from direct sun light. Source: Whole plant. Species: Arnica montana. Arnica Extract; Arnica montana; plant extract. Pack: 25KG/Drum with double plastic bag of foodstuff inside. Cat No: EXTW-176.
Arnicolide C is found in the herbs of Centipeda minima, it shows significant antiallergy activity. Synonyms: Arnicolide C; ArnicolideC; 34532-67-7; [(1S,3aR,5R,5aR,8aR,9S,9aR)-1,5,8a-trimethyl-2,8-dioxo-3a,4,5,5a,9,9a-hexahydro-1H-azuleno[6,5-b]furan-9-yl] 2-methylpropanoate; HY-N6842; AKOS030632143; NCGC00347562-02; MS-25050; 1ST167749; CS-0100261; E80740. Grades: > 95%. CAS No. 34532-67-7. Molecular formula: C19H26O5. Mole weight: 334.41.
Arnidiol
Arnidiol is a triterpenoid with anti-inflammatory activity. Synonyms: Arnidenediol; Ainidiol. Grades: 0.98. CAS No. 6750-30-7. Molecular formula: C30H48O2. Mole weight: 440.7.
Arnifolin
Arnifolin. Uses: Designed for use in research and industrial production. Additional or Alternative Names: CID6450253, CID 6450253, 2-Butanoic acid, 2-methyl-, dodecahydro-7-hydroxy-4a,8-dimethyl-3-methylene-2,5-dioxoazuleno(6,5-b)furan-4-yl ester, 25644-08-0. Appearance: White powder. CAS No. 25644-08-0. Molecular formula: C20H26O6. Mole weight: 362.42. Purity: 97%+. IUPACName: (6-hydroxy-5,8a-dimethyl-1-methylidene-2,8-dioxo-3a,4,5,5a,6,7,9,9a-octahydroazuleno[6,5-b]furan-9-yl) (E)-2-methylbut-2-enoate. Canonical SMILES: CC=C(C)C(=O)OC1C2C(CC(C3C1(C(=O)CC3O)C)C)OC(=O)C2=C. Density: 1.23g/cm³. Product ID: ACM25644080. Alfa Chemistry ISO 9001:2015 Certified.
Arnite
Arnite. Group: Polymers.
Arnitel
Arnitel. Group: Polymers.
arogenate dehydratase
Also acts on prephenate and D-prephenyllactate. cf. EC 4.2.1.51, prephenate dehydratase. Group: Enzymes. Synonyms: carboxycyclohexadienyl dehydratase; L-arogenate hydro-lyase (decarboxylating). Enzyme Commission Number: EC 4.2.1.91. CAS No. 76600-70-9. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5075; arogenate dehydratase; EC 4.2.1.91; 76600-70-9; carboxycyclohexadienyl dehydratase; L-arogenate hydro-lyase (decarboxylating). Cat No: EXWM-5075.
arogenate dehydrogenase
Arogenate dehydrogenases may utilize NAD+ (EC 1.3.1.43), NADP+ (EC 1.3.1.78), or both (EC 1.3.1.79). NAD+-specific enzymes have been reported from some bacteria and plants. Some enzymes also possess the activity of EC 1.3.1.12, prephenate dehydrogenase. Group: Enzymes. Synonyms: arogenic dehydrogenase (ambiguous); cyclohexadienyl dehydrogenase; pretyrosine dehydrogenase (ambiguous); L-arogenate:NAD+ oxidoreductase; arogenate dehydrogenase (NAD+). Enzyme Commission Number: EC 1.3.1.43. CAS No. 64295-75-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1315; arogenate dehydrogenase; EC 1.3.1.43; 64295-75-6; arogenic dehydrogenase (ambiguous); cyclohexadienyl dehydrogenase; pretyrosine dehydrogenase (ambiguous); L-arogenate:NAD+ oxidoreductase; arogenate dehydrogenase (NAD+). Cat No: EXWM-1315.
arogenate dehydrogenase (NADP+)
Arogenate dehydrogenases may utilize NAD+ (EC 1.3.1.43), NADP+ (EC 1.3.1.78), or both (EC 1.3.1.79). NADP+-dependent enzymes usually predominate in higher plants.The enzyme from the cyanobacterium Synechocystis sp. PCC 6803 and the TyrAAT1 isoform of the plant Arabidopsis thaliana cannot use prephenate as a substrate, while the Arabidopsis isoform TyrAAT2 can use it very poorly. Group: Enzymes. Synonyms: arogenic dehydrogenase (ambiguous); pretyrosine dehydrogenase (ambiguous); TyrAAT1; TyrAAT2; TyrAa. Enzyme Commission Number: EC 1.3.1.78. CAS No. 64295-75-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1347; arogenate dehydrogenase (NADP+); EC 1.3.1.78; 64295-75-6; arogenic dehydrogenase (ambiguous); pretyrosine dehydrogenase (ambiguous); TyrAAT1; TyrAAT2; TyrAa. Cat No: EXWM-1347.
arogenate dehydrogenase [NAD(P)+]
Arogenate dehydrogenases may utilize NAD+ (EC 1.3.1.43), NADP+ (EC 1.3.1.78), or both (EC 1.3.1.79). Enzymes that can utilize both cofactors have been reported from some Proteobacteria, including Burkholderia caryophylli, Burkholderia cepacia, Pseudomonas marginata and Delftia acidovorans. Group: Enzymes. Synonyms: arogenic dehydrogenase (ambiguous); cyclohexadienyl dehydrogenase; pretyrosine dehydrogenase (ambiguous). Enzyme Commission Number: EC 1.3.1.79. CAS No. 64295-75-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1348; arogenate dehydrogenase [NAD(P)+]; EC 1.3.1.79; 64295-75-6; arogenic dehydrogenase (ambiguous); cyclohexadienyl dehydrogenase; pretyrosine dehydrogenase (ambiguous). Cat No: EXWM-1348.
Arohynapene A
Arohynapene A is an anti-coccidial antibiotic produced by Pemcillum sp. FO-2295. Arohynapene A has no antibacterial activity. Synonyms: 5-(5-Hydroxy-2,6,8-trimethyl-5,6,7,8-tetrahydronaphthalene)-2,4-pentadienoic acid; 2,4-Pentadienoic acid, 5-(5,6,7,8-tetrahydro-5-hydroxy-2,6,8-trimethyl-1-naphthalenyl)-. CAS No. 154445-08-6. Molecular formula: C18H22O3. Mole weight: 286.36.
Arohynapene B
Arohynapene B is an anti-coccidial antibiotic produced by Pemcillum sp. FO-2295. It has no antibacterial activity. Synonyms: 5-(2-Hydroxymethyl-6,8-dimethyl-5,6,7,8-tetrahydronaphthalene)-2,4-pentadienoic acid; 2,4-Pentadienoic acid, 5-(5,6,7,8-tetrahydro-2-(hydroxymethyl)-6,8-dimethyl-1-naphthalenyl)-. CAS No. 154445-09-7. Molecular formula: C18H22O3. Mole weight: 286.36.
Arohynapene D
Arohynapene D is an anti-coccidial antibiotic produced by Pemcillum sp. FO-2295. The MIC that Arohynapene D shows toxicity to BHK-21 cells is 1.0 X 10-6 mol/L. Molecular formula: C11H14O3. Mole weight: 194.23.
Aromadendrene
Aromadendrene can be isolated from Eucalyptus globulus. Aromadendrene has antimicrobial activity [1]. Uses: Scientific research. Group: Natural products. Alternative Names: (+)-Aromadendrene. CAS No. 489-39-4. Pack Sizes: 5 mg; 10 mg. Product ID: HY-N8411.
Aromadendrene oxide 2
Aromadendrene oxide 2 (CAS# 85710-39-0 ) is a useful research chemical. Synonyms: (1aR,4S,4aR,7R,7aS,7bS)-1,1,7-trimethylspiro[2,3,4a,5,6,7,7a,7b-octahydro-1aH-cyclopropa[e]azulene-4,2'-oxirane]. CAS No. 85710-39-0. Molecular formula: C15H24O. Mole weight: 220.35.
aromatase
A cytochrome P-450. The enzyme catalyses three sequential hydroxylations of the androgens androst-4-ene-3,17-dione and testosterone, resulting in their aromatization and forming the estrogens estrone and 17β-estradiol, respectively. The direct electron donor to the enzyme is EC 1.6.2.4, NADPH-hemoprotein reductase. Group: Enzymes. Synonyms: CYP19A1 (gene name); estrogen synthetase (incorrect). Enzyme Commission Number: EC 1.14.14.14. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0911; aromatase; EC 1.14.14.14; CYP19A1 (gene name); estrogen synthetase (incorrect). Cat No: EXWM-0911.
Aromatase-IN-2
Aromatase-IN-2 is a potent aromatase inhibitor with an IC 50 value of 1.5 μM [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 121768-39-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-148430.
aromatic-amino-acid-glyoxylate transaminase
Phenylalanine, kynurenine, tyrosine and histidine can act as amino donors; glyoxylate, pyruvate and hydroxypyruvate can act as amino acceptors. Group: Enzymes. Enzyme Commission Number: EC 2.6.1.60. CAS No. 67185-76-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2902; aromatic-amino-acid-glyoxylate transaminase; EC 2.6.1.60; 67185-76-6. Cat No: EXWM-2902.
aromatic-amino-acid transaminase
A pyridoxal-phosphate protein. L-Methionine can also act as donor, but more slowly; oxaloacetate can act as acceptor. Controlled proteolysis converts the enzyme into EC 2.6.1.1 aspartate transaminase. Group: Enzymes. Synonyms: aromatic amino acid aminotransferase; aromatic aminotransferase; ArAT. Enzyme Commission Number: EC 2.6.1.57. CAS No. 37332-38-0. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2898; aromatic-amino-acid transaminase; EC 2.6.1.57; 37332-38-0; aromatic amino acid aminotransferase; aromatic aminotransferase; ArAT. Cat No: EXWM-2898.
Aromatic hydrocarbons, C6-10, C8-rich
Aromatic hydrocarbons, C6-10, C8-rich. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Aromatic hydrocarbons, C6-10, C8-rich;Aromatic hydrocarbons, C6-10, C8-rich Light Oil Redistillate, low boiling. Product Category: Heterocyclic Organic Compound. CAS No. 90989-41-6. Product ID: ACM90989416. Alfa Chemistry ISO 9001:2015 Certified.
aromatic-hydroxylamine O-acetyltransferase
Transfers the N-acetyl group of some aromatic acethydroxamates to the O-position of some aromatic hydroxylamines. Group: Enzymes. Synonyms: aromatic hydroxylamine acetyltransferase; arylhydroxamate acyltransferase; arylhydroxamate N,O-acetyltransferase; arylhydroxamic acid N,O-acetyltransferase; arylhydroxamic acyltransferase; N,O-acetyltransferase; N-hydroxy-2-acetylaminofluorene N-O acyltransferase. Enzyme Commission Number: EC 2.3.1.56. CAS No. 52660-15-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2235; aromatic-hydroxylamine O-acetyltransferase; EC 2.3.1.56; 52660-15-8; aromatic hydroxylamine acetyltransferase; arylhydroxamate acyltransferase; arylhydroxamate N,O-acetyltransferase; arylhydroxamic acid N,O-acetyltransferase; arylhydroxamic acyltransferase; N,O-acetyltransferase; N-hydroxy-2-acetylaminofluorene N-O acyltransferase. Cat No: EXWM-2235.
aromatic-L-amino-acid decarboxylase
A pyridoxal-phosphate protein. The enzyme also acts on some other aromatic L-amino acids, including L-tryptophan, L-tyrosine and L-phenylalanine. Group: Enzymes. Synonyms: DOPA decarboxylase; tryptophan decarboxylase; hydroxytryptophan decarboxylase; L-DOPA decarboxylase; aromatic amino acid decarboxylase; 5-hydroxytryptophan decarboxylase; aromatic-L-amino-acid carboxy-lyase (tryptamine-forming). Enzyme Commission Number: EC 4.1.1.28. CAS No. 9042-64-2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4771; aromatic-L-amino-acid decarboxylase; EC 4.1.1.28; 9042-64-2; DOPA decarboxylase; tryptophan decarboxylase; hydroxytryptophan decarboxylase; L-DOPA decarboxylase; aromatic amino acid decarboxylase; 5-hydroxytryptophan decarboxylase; aromatic-L-amino-acid carboxy-lyase (tryptamine-forming). Cat No: EXWM-4771.
Aromatic solvents
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Aronia P.E. 4:1
Aronia P.E. 4:1.
CA, FL & NJ
Aroplatin
Aroplatin is a synthetic liposomal formulation of bis-neodecanoate diaminocyclohexane platinum (NDDP), a third-generation platinum complex analogue of cisplatin, with potential antineoplastic activity. The liposomal encapsulation improves the bioavailability of NDDP and reduces its toxicity profile. CAS No. 114488-24-3. Molecular formula: C26H52N2O4Pt. Mole weight: 651.79.
Arotinoid
Arotinoid (RO 13-6298) is a retinoid, and acts as an orally active and highly potent agonist of retinoic acid receptors ( RARs ) with antipsoriatic effects. Arotinoid has antipapiltoma activity with an ED 50 of 0.05 mg/kg. Arotinoid can be used for the research of skin carcinomas [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Ro 13-6298; Arotinoid ethyl ester. CAS No. 71441-09-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-106735.
Arotinolol
Arotinolol is both and alpha- and beta-adrenoceptor antagonist and is used to treat essential tremors and hypertension. Group: Biochemicals. Grades: Highly Purified. CAS No. 68377-92-4. Pack Sizes: 100mg, 1g. Molecular Formula: C15H21N3O2S3. US Biological Life Sciences.
Worldwide
Arotinolol
Arotinolol. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 5-(2-((3-(tert-butylamino)-2-hydroxypropyl)thio)thiazol-4-yl)thiophene-2-carboxamide. CAS No. 68377-92-4. Molecular Formula: C15H21N3O2S3. Mole Weight: 371.54. Catalog: APB68377924.
Arotinolol
Arotinolol is a nonselective α/β-adrenergic receptor blocker and a vasodilating β-blocker [1]. Arotinolol also shows potency for inhibiting the binding of the radioligand 125 I-ICYP to 5HT 1B -serotonergic receptor sites [2]. Arotinolol is an antihypertensive agent for the treatment of a variety of cardiovascular pathologies as well as non-cardiovascular diseases [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 68377-92-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-122537A.
Arotinolol HCl
Arotinolol HCl. Uses: For analytical and research use. Group: Impurity standards. CAS No. 68377-91-3. Molecular Formula: C15H22ClN3O2S3. Mole Weight: 407.99. Catalog: APB68377913.
Arotinolol hydrochloride
Arotinolol hydrochloride. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 5-[2-[[3-(tert-Butylamino)-2-hydroxypropyl]thio]thiazol-4-yl]thiophene-2-carboxamide Hydrochloridel. Product Category: Thiophenes. CAS No. 68377-91-3. Molecular formula: C15H22ClN3O2S3. Mole weight: 407.99. Purity: 0.98. Product ID: ACM68377913. Alfa Chemistry ISO 9001:2015 Certified.
Arotinolol impurity 1
Arotinolol impurity 1. Uses: For analytical and research use. Group: Impurity standards. CAS No. 52560-89-1. Molecular Formula: C8H6N2OS3. Mole Weight: 242.33. Catalog: APB52560891.
Arotinolol Impurity 1
Arotinolol Impurity 1. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 5-acetylthiophene-2-carboxamide. CAS No. 68257-89-6. Molecular Formula: C7H7NO2S. Mole Weight: 169.2. Catalog: APB68257896.
Arotinolol Impurity 11
Arotinolol Impurity 11. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: oxiran-2-ylmethanol. CAS No. 556-52-5. Molecular Formula: C3H6O2. Mole Weight: 74.08. Catalog: APB556525.
Arotinolol impurity 2
Arotinolol impurity 2. Uses: For analytical and research use. Group: Impurity standards. CAS No. 13080-65-4. Molecular Formula: C7H15NO. Mole Weight: 129.2. Catalog: APB13080654.
Arotinolol Impurity 2
Arotinolol Impurity 2. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 5-acetylthiophene-2-carboxylic acid. CAS No. 4066-41-5. Molecular Formula: C7H6O3S. Mole Weight: 170.19. Catalog: APB4066415.
Arotinolol impurity 3
Arotinolol impurity 3. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C15H19N3OS3. Mole Weight: 353.52. Catalog: APB12279.
Arotinolol Impurity 3
Arotinolol Impurity 3. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: carbamodithioic acid, ammonia salt. CAS No. 513-74-6. Molecular Formula: CH6N2S2. Mole Weight: 110.2. Catalog: APB513746.
Arotinolol Impurity 4
Arotinolol Impurity 4. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 5-(2-bromoacetyl)thiophene-2-carboxamide. CAS No. 68257-90-9. Molecular Formula: C7H6BrNO2S. Mole Weight: 248.1. Catalog: APB68257909.
Arotinolol Impurity 6
Arotinolol Impurity 6. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 2,3-dichloropropan-1-ol. CAS No. 616-23-9. Molecular Formula: C3H6Cl2O. Mole Weight: 128.99. Catalog: APB616239.
Arotinolol impurity 8
Arotinolol impurity 8. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1682660-95-2. Molecular Formula: C8H6N2O2S2. Mole Weight: 226.27. Catalog: APB1682660952.
ARP 100
ARP 100. Group: Biochemicals. Grades: Purified. CAS No. 704888-90-4. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
ARP 100
ARP 100 has been found to be a selective inhibitor of MMP-2 and could show anti-invasive properties in HT1080 fibrosarcoma cells at some extent. Synonyms: ARP100; ARP-100; ARP 100; 2-[((1,1'-Biphenyl)-4-ylsulfonyl)-(1-methylethoxy)amino]-N-hydroxyacetamide. Grades: ≥98% by HPLC. CAS No. 704888-90-4. Molecular formula: C17H20N2O5S. Mole weight: 364.42.
ARP 101
ARP 101 is a Selective MMP-2 inhibitor with IC50 value of 0.81 nM. It displays nearly 600-fold selectivity over MMP-1 (IC50 value 486 nM). ARP 101 has diverse physiological roles including wound healing, cancer metastasis, angiogenesis and so on. Synonyms: ARP-101; ARP 101; ARP101; (2R)-N-hydroxy-3-methyl-2-[(4-phenylphenyl)sulfonyl-propan-2-yloxyamino]butanamide. Grades: 98%. CAS No. 849773-63-3. Molecular formula: C20H26N2O5S. Mole weight: 406.50.
ARP 101
ARP 101. Group: Biochemicals. Grades: Purified. CAS No. 849773-63-3. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
Arphamenine a
Arphamenine a. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Arphamenine A, Arphamenine A hydrochloride, C16H24N4O3.HCl, CID5487157, LS-31060, 5-amino-8-guanidino-4-oxo-2-phenylmethyloctanoic acid, 5-Amino-8-guanidino-4-oxo-2-phenylmethyloctanoic acid hydrochloride, Benzenepropanoic acid, alpha-(3-amino-6-((aminoiminomethyl)amino)-2-oxohexyl)-, monohydrochloride, (S-(R*,S*))-, 85713-14-0, Benzenepropanoic acid, alpha-(3-amino-6-((aminoiminomethyl)amino)-2-oxohexyl)-,monohydrochloride, (S-(R*,S*))-. Product Category: Heterocyclic Organic Compound. CAS No. 85713-14-0. Molecular formula: C32H50N8O10S. Mole weight: 356.847700 [g/mol]. Purity: 0.96. IUPACName: (2R,5S)-5-amino-2-benzyl-8-(diaminomethylideneamino)-4-oxooctanoic acid hydrochloride. Product ID: ACM85713140. Alfa Chemistry ISO 9001:2015 Certified.
Arphamenine A
Arphamenine A is an enzyme inhibitor produced by Chromobacteriuin violaceum HMG361-CF4. It can inhibit the activity of aminopeptidase B, and can inhibit sarcoma 180 and IMC cancer. Synonyms: Benzenepropanoic acid, α-[(3S)-3-amino-6-[(aminoiminomethyl)amino]-2-oxohexyl]-, (αR)-; (αR)-α-[(3S)-3-Amino-6-[(aminoiminomethyl)amino]-2-oxohexyl]benzenepropanoic acid; Benzenepropanoic acid, α-[3-amino-6-[(aminoiminomethyl)amino]-2-oxohexyl]-, [S-(R*,S*)]-; Arphamenin A. Grades: ≥95%. CAS No. 96551-81-4. Molecular formula: C16H24N4O3. Mole weight: 320.39.
Arphamenine B
Arphamenine B is a specific inhibitor of aminopeptidase B, which is first isolated from bacteria. Arphamenine B shares the same properties as the aminopeptidase inhibitors bestatin and amastatin, both of which enhance the immune response. Synonyms: Benzenepropanoic acid, α-[(3S)-3-amino-6-[(aminoiminomethyl)amino]-2-oxohexyl]-4-hydroxy-, (αR)-; (αR)-α-[(3S)-3-Amino-6-[(aminoiminomethyl)amino]-2-oxohexyl]-4-hydroxybenzenepropanoic acid; Benzenepropanoic acid, α-[3-amino-6-[(aminoiminomethyl)amino]-2-oxohexyl]-4-hydroxy-, [S-(R*,S*)]-; Arphamenin B. Grades: 95%. CAS No. 103900-19-2. Molecular formula: C16H24N4O4. Mole weight: 336.39.
Arphamenine B hemisulfate
Arphamenine B is a specific inhibitor of aminopeptidase B, which is first isolated from bacteria. Arphamenine B Hemisulfate is the hemisulfate form. Arphamenine B share the same property with aminopeptidase inhibitors bestatin and amastatin, they all enhance imune responses. Synonyms: Benzenepropanoic acid, α-[(3S)-3-amino-6-[(aminoiminomethyl)amino]-2-oxohexyl]-4-hydroxy-, (αR)-, sulfate (2:1) (salt); Benzenepropanoic acid, α-[3-amino-6-[(aminoiminomethyl)amino]-2-oxohexyl]-4-hydroxy-, monohydrochloride, [S-(R*,S*)]-, sulfate (2:1) (salt); Arphamenine B sulfate; (αR)-α-[(3S)-3-Amino-6-[(aminoiminomethyl)amino]-2-oxohexyl]-4-hydroxybenzenepropanoic acid, sulfate (2:1) (salt). Grades: ≥95%. CAS No. 144110-38-3. Molecular formula: C16H24N4O4·1/2H2SO4. Mole weight: 385.43.
Arprinocid
A Coccidiostat used in veterinary medicine. Group: Biochemicals. Alternative Names: 9-[(2-Chloro-6-fluorophenyl)methyl]-9H-purin-6-amine; 6-Amino-9-(2-chloro-6-fluorobenzyl)purine; Arpocox; MK 302. Grades: Highly Purified. CAS No. 55779-18-5. Pack Sizes: 100mg. US Biological Life Sciences.
Worldwide
ARQ-087
ARQ-087, also known as Derazantinib, is an oral fibroblast growth factor receptor (FGFR) inhibitor with antitumor property. FGFR plays a role in the regulation of key cellular behaviors including proliferation, cell differentiation and so on. FGFR dysregulation is considered as a driver in multiple cancers. ARQ 087 binds to FGFR and effectively inhibits the activation of FGFR thus can suppress tumorigenesis and tumor growth. Synonyms: ARQ 087; ARQ087; ARQ-087; Derazantinib; (6R)-6-(2-fluorophenyl)-N-[3-[2-(2-methoxyethylamino)ethyl]phenyl]-5,6-dihydrobenzo[h]quinazolin-2-amine. Grades: ≥98%. CAS No. 1234356-69-4. Molecular formula: C29H29FN4O. Mole weight: 468.576.
ARQ-092
ARQ-092, also called as Miransertib, is an oral activie, potent and selective AKT inhibitor with IC50=5.0 nM against AKT1, 4.5 nM against AKT2 and 16 nM against AKT3. ARQ-092 inhibits the PI3K/AKT signaling pathway due to inhibition of the activity of AKT in a non-ATP competitive manner. This may lead to the reduction in tumor cell proliferation and the induction of tumor cell apoptosis. Synonyms: 3-(3-(4-(1-aminocyclobutyl)phenyl)-5-phenyl-3H-imidazo[4,5-b]pyridin-2-yl)pyridin-2-amine; ARQ092; ARQ-092; ARQ 092; Miransertib. Grades: >98%. CAS No. 1313881-70-7. Molecular formula: C27H24N6. Mole weight: 432.53.
ARQ 531
ARQ-531 is a potent and orally active BTK inhibitor with potential antineoplastic activity. ARQ 531 is a reversible non-covalent inhibitor of Bruton's Tyrosine Kinase (BTK), with IC50s of 0.85 nM and 0.39 nM for WT-BTK and C481S-BTK, respectively. It also has a distinct kinase selectivity profile with strong inhibitory activity against several key oncogenic drivers from TEC, Trk and Src family kinases. In GCB-DLBCL cell lines (SUDHL-4 and DOHH-2), ARQ 531 potently suppressed expression of anti-apoptotic c-Myc and BCL6 oncoproteins in a dose-dependent fashion, and concomitantly induced apoptotic cleavage of PARP protein. Synonyms: ARQ-531. Grades: ≥98%. CAS No. 2095393-15-8. Molecular formula: C25H23ClN4O4. Mole weight: 478.93.