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| Product | Description | |
|---|---|---|
| cGAS-IN-2 | cGAS-IN-2 (compound 109) is a potent inhibitor of Cyclic GMP-AMP Synthase (cGAS), with IC 50 of 0.01512 μM for h-cGAS [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2765273-11-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-160546. |  |
| CGC-11047 | CGC-11047 is a second generation polyamine analogue, synthesized through the restriction of molecular conformations of parent polyamine compounds, with potential antineoplastic activity. Polyamine analogue PG11047 may displace endogenous polyamines from DNA binding sites, thereby interfering with cell cycle processes dependent upon polyamine binding and function, and resulting in cell-cycle arrest, induction of apoptosis, depletion of polyamines, and interference with gene and ligand-receptor activities involved with cell growth. This agent may exhibit decreased toxicity and enhanced cytotoxicity profiles compared to first-generation polyamine compounds. In tumor cells, there is an increase dependence on polyamines as well as a dysregulated polyamine metabolic pathway resulting in abnormal or sustained tumor growth. Synonyms: CGC 11047; CGC11047; SL 11047; SL 47; SL47. CAS No. 206991-64-2. Molecular formula: C14H36Cl4N4. Mole weight: 402.27. |  |
| CGGRGD acetate | CGGRGD acetate is a RGD derivative with cysteine as the n-terminal. CGGRGD was synthesized by solid phase peptide synthesis technology, and amino2-cyanobenzothiazole (2-cyanobenzothiazole) (2-cyanobenzothiazole (CBT) was added on the surface of PCL fiber for ammoniation. Molecular formula: C21H37N9O11S. Mole weight: 623.65. | |
| Cgh 2466 | Cgh 2466. Uses: Designed for use in research and industrial production. Additional or Alternative Names: CGH 2466, CID5282339, C14128, LS-192831, BRD-K82028950-300-01-1, 252198-68-8. Product Category: Heterocyclic Organic Compound. CAS No. 252198-68-8. Molecular formula: C14H9N3SCl2.2HCl. Mole weight: 322.21236. Purity: >99 %. IUPACName: 4-(3,4-dichlorophenyl)-5-pyridin-4-yl-1,3-thiazol-2-amine. Canonical SMILES: C1=CC(=C(C=C1C2=C(SC(=N2)N)C3=CC=NC=C3)Cl)Cl. Density: 1.45g/cm³. Product ID: ACM252198688. Alfa Chemistry ISO 9001:2015 Certified. |  |
| CGH 2466 dihydrochloride | CGH 2466 dihydrochloride is an adenosine A1, A2B and A3 receptor antagonist (IC50 = 19, 21, and 80 nM, respectively). It also displays an inhibitory effect on p38 MAPK (IC50 = 187 - 400 nM) and phosphodiesterase type 4D (IC50 = 22 nM). CGH 2466 is potentially used for the treatment of asthma and chronic obstructive pulmonary disease (COPD). Uses: Potential treatment of asthma and copd. Synonyms: CGH 2466 dihydrochloride; CGH2466 dihydrochloride; CGH-2466 dihydrochloride; 4-(3,4-Dichlorophenyl)-5-(4-pyridinyl)-2-thiazolamine dihydrochloride. Grades: ≥99% by HPLC. CAS No. 1177618-54-0. Molecular formula: C14H9N3SCl2.2HCl. Mole weight: 395.13. | |
| CGH 2466 dihydrochloride | CGH 2466 dihydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 1177618-54-0. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. |  Worldwide |
| CGI1746 | CGI1746 is a small-molecule Btk inhibitor chemotype with a new binding mode that stabilizes an inactive nonphosphorylated enzyme conformation. CGI1746 has exquisite selectivity for Btk and inhibits both auto- and transphosphorylation steps necessary for enzyme activation. Synonyms: CGI1746; CGI-1746; CGI 1746. 4-(tert-Butyl)-N-(2-methyl-3-(4-methyl-6-((4-(morpholine-4-carbonyl)phenyl)amino)-5-oxo-4,5-dihydropyrazin-2-yl)phenyl)benzamide. Grades: 98%. CAS No. 910232-84-7. Molecular formula: C34H37N5O4. Mole weight: 579.69. | |
| CGI1746 | CGI1746 is a small-molecule Btk inhibitor chemotype with a new binding mode that stabilizes an inactive nonphosphorylated enzyme conformation. CGI1746 has exquisite selectivity for Btk and inhibits both auto- and transphosphorylation steps necessary for enzyme activation. Uses: Designed for use in research and industrial production. Additional or Alternative Names: CGI1746; CGI-1746; CGI 1746. Product Category: Inhibitors. Appearance: White to off-white solid powder. CAS No. 910232-84-7. Molecular formula: C34H37N5O4. Mole weight: 579.69. Purity: >98%. IUPACName: 4-(tert-butyl)-N-(2-methyl-3-(4-methyl-6-((4-(morpholine-4-carbonyl)phenyl)amino)-5-oxo-4,5-dihydropyrazin-2-yl)phenyl)benzamide. Canonical SMILES: O=C(NC1=CC=CC(C(N=C2NC3=CC=C(C(N4CCOCC4)=O)C=C3)=CN(C)C2=O)=C1C)C5=CC=C(C(C)(C)C)C=C5. Product ID: ACM910232847. Alfa Chemistry ISO 9001:2015 Certified. | |
| CGI560 | CGI560 is a potent BTK inhibitor with IC50 = 400 nM for BTK. Synonyms: CGI-560; CGI 560; 4-(tert-Butyl)-N-(3-(8-(phenylamino)imidazo[1,2-a]pyrazin-6-yl)phenyl)benzamide. CAS No. 845269-74-1. Molecular formula: C29H27N5O. Mole weight: 461.57. | |
| CGK733 | ?98% (HPLC), solid. Group: Fluorescence/luminescence spectroscopy. |  |
| CGK733 | CGK733. Group: Biochemicals. Alternative Names: α -Phenyl-N- [2, 2, 2-trichloro-1- [ [ [ (4-fluoro-3-nitrophenyl) amino] thioxomethyl] amino] ethyl] benzeneacetamide. Grades: Highly Purified. CAS No. 905973-89-9. Pack Sizes: 5mg. Molecular Formula: C23H18Cl3FN4O3S, Molecular Weight: 555.84. US Biological Life Sciences. | Worldwide |
| CGK733 | CGK733, a thiourea-containing compound, was originally identified as a specific inhibitor of ATR and ATM kinases (IC50 = ~ 200 nM). In prematurely senescent breast, lung, and colon cancer cells CGK733 reportedly suppresses ATM-mediated p21 expression required for survival, resulting in cell death. Synonyms: CGK733; CGK-733; CGK 733. CAS No. 905973-89-9. Molecular formula: C23H18Cl3FN4O3S. Mole weight: 555.84. | |
| CGK 733 | CGK 733. Group: Biochemicals. Grades: Purified. CAS No. 905973-89-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| CGM097 | CGM097 is an orally bioavailable HDM2 (human homolog of double minute 2) antagonist with potential antineoplastic activity. Upon oral administration, p53/HDM2 interaction inhibitor CGM097 inhibits the binding of the HDM2 protein to the transcriptional activation domain of the tumor suppressor protein p53. By preventing this HDM2-p53 interaction, the proteosome-mediated enzymatic degradation of p53 is inhibited, which may result in the restoration of p53 signaling and, thus, the p53-mediated induction of tumor cell apoptosis. HDM2, a zinc finger nuclear phosphoprotein, is a negative regulator of the p53 pathway, often overexpressed in cancer cells and has been implicated in cancer cell proliferation and survival. Synonyms: CGM097; CGM-097; CGM 097; NVPCGM097; NVPCGM 097; NVPCGM-097; NVP CGM097; NVP CGM 097; NVP CGM-097. CAS No. 1313363-54-0. Molecular formula: C38H47ClN4O4. Mole weight: 659.27. | |
| cgMolluscidin | CgMolluscidin is a novel dibasic residue repeat rich antimicrobial peptide, purified from the gill of the Pacific oyster, Crassostrea gigas. CgMolluscidin showed potent antimicrobial activity against both Gram-positive bacteria, including Bacillus subtilis, Micrococcus luteus, and Staphylococcus aureus (minimal effective concentrations [MECs]; 1.3-31.3 μg/mL), and Gram-negative bacteria, including Escherichia coli, Salmonella enterica, and Vibrio parahaemolyticus ([MECs]; 0.4-2.3 μg/mL), without hemolytic activity. | |
| cGMP | cGMP, a cyclic guanosine monophosphate, possesses an essential role in governing numerous physiological processes. Significantly employed as a pharmacological focal point in the biomedical realm to combat the likes of hypertension and pulmonary arterial hypertension, its potency is immense. Furthermore, it is intricately involved in the signal transduction pathways of selected neurotransmitters and hormones. Synonyms: Guanosine-3',5'-cyclic monophosphate, Sodium salt. Grades: ≥ 95% by HPLC. Molecular formula: C10H12N5O7P (free acid). Mole weight: 345.20 (free acid). | |
| cGMP-AM | cGMP-AM is a precursor of cGMP, the second messenger. The polar active analogue is released after the metabolism of cGMP-AM by esterases. Synonyms: Guanosine- 3', 5'- cyclic monophosphate, acetoxymethyl ester. Grades: ≥ 95% by HPLC for mixture of isomers. CAS No. 164007-71-0. Molecular formula: C13H16N5O9P. Mole weight: 417.3. | |
| cGMP Dependent Kinase Inhibitor Peptide | cGMP Dependent Kinase Inhibitor Peptide. Group: Biochemicals. Grades: Purified. CAS No. 82801-73-8. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| cGMP Dependent Kinase Inhibitor Peptide | PKG Inhibitor is a competitive inhibitor of cGMP-dependent protein kinase (PKG). It is an analog of a substrate peptide corresponding to a phosphorylation site of histone H2B, and inhibits phosphorylation of intact histones by PKA. Synonyms: cGMP Dependent Kinase Inhibitor Peptide. Grades: >98%. CAS No. 82801-73-8. Molecular formula: C38H74N18O10. Mole weight: 943.12. | |
| cGMP-dependent protein kinase | CGMP is required to activate this enzyme. The enzyme occurs as a dimer in higher eukaryotes. The C-terminal region of each polypeptide chain contains the catalytic domain that includes the ATP and protein substrate binding sites. This domain catalyses the phosphorylation by ATP to specific serine or threonine residues in protein substrates. The enzyme also has two allosteric cGMP-binding sites (sites A and B). Binding of cGMP causes a conformational change that is associated with activation of the kinase. Group: Enzymes. Synonyms: 3':5'-cyclic GMP-dependent protein kinase; cGMP-dependent protein kinase Iβ; guanosine 3':5'-cyclic monophosphate-dependent protein kinase; PKG; PKG 1α; PKG 1β; PKG II; STK23. Enzyme Commission Number: EC 2.7.11.12. CAS No. 141588-27-4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3131; cGMP-dependent protein kinase; EC 2.7.11.12; 141588-27-4; 3':5'-cyclic GMP-dependent protein kinase; cGMP-dependent protein kinase Iβ; guanosine 3':5'-cyclic monophosphate-dependent protein kinase; PKG; PKG 1α; PKG 1β; PKG II; STK23. Cat No: EXWM-3131. |  |
| Cgp-11130 | Cgp-11130 is a GABAB receptor agonist which was never marketed. It is selective for the GABAB receptor over the GABAA receptor (IC50 = 1.70 μM and > 100 μM, respectively). Synonyms: Cgp 11130; Cgp11130; β-(Aminomethyl)-4-fluorobenzenepropanoic acid. Grades: 98%. CAS No. 52237-19-1. Molecular formula: C10H12FNO2. Mole weight: 197.21. | |
| Cgp-11952 | Cas No. 64078-09-7. | |
| CGP 12177 | CGP 12177 is a partial β3-adrenoceptor agonist with Ki value of 88 nM. It is also an of β1- and β2-adrenoceptors antagonist with Ki values of 0.9 nM and 4 nM for β1-, β2adrenoceptors. CGP12177 can slightly activate L-type Ca2+ current in human ventricular myocytes. Uses: Adrenergic beta-antagonists. Synonyms: CGP 12177; CGP12177; CGP-12177; Tbhpbo; CGP 12177 Hydrochloride; CGP 12177 HCl. 4-[3-[(1,1-Dimethylethyl)amino]2-hydroxypropoxy]-1,3-dihydro-2H-benzimidazol-2-one;64208-32-8(hydrochloride). Grades: 98%. CAS No. 81047-99-6. Molecular formula: C14H21N3O3. Mole weight: 279.34. | |
| CGP 12177 hydrochloride | CGP 12177 hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 64208-32-8. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| CGP 12177 hydrochloride | CGP 12177 hydrochloride is a partial agonist of β3-adrenoceptors, and also an antagonist of β1- and β2-adrenoceptors (Ki = 0.9, 4 and 88 nM for β1, β2 and β3 receptors respectively). Synonyms: CGP 12177 hydrochloride; CGP12177 hydrochloride; CGP-12177 hydrochloride; 4-[3-[(1,1-Dimethylethyl)amino]2-hydroxypropoxy]-1,3-dihydro-2H-benzimidazol-2-one hydrochloride. CAS No. 64208-32-8. Molecular formula: C14H21N3O3.HCl. Mole weight: 315.8. | |
| CGP 12177 hydrochloride | CGP 12177 ((±)-CGP 12177) hydrochloride is a β Adrenergic Receptor Ligand. CGP 12177 hydrochloride is a high affinity antagonist of β1- and β2-AR. CGP 12177 hydrochloride is also shown to interact, with a lower affinity, with the β3-AR and to exhibit a partial agonist activity on rodent and human β3-AR. CGP 12177 hydrochloride exhibits partial agonist properties for α1-AR in rat pulmonary artery [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (±)-CGP 12177 hydrochloride. CAS No. 64208-32-8. Pack Sizes: 5 mg; 10 mg. Product ID: HY-101393A. | |
| CGP-12388 | CGP-12388 is a beta-adrenoceptor antagonist-derived radioligands. It is used for cardiac PET imaging due to its high hydrophilicity and affinity to beta-adrenoceptor. Uses: Cgp-12388 is used for cardiac pet imaging due to its high hydrophilicity and affinity to beta-adrenoceptor. Synonyms: 4-(3-(Isopropylamino)-2-Hydroxypropoxy)-2H-Benzimidazol-2-One;Cgp 12388; Cgp-12388; Cgp12388;2H-Benzimidazol-2-one, 4-(3-(isopropylamino)-2-hydroxypropoxy)-;4-[2-hydroxy-3-(propan-2-ylamino)propoxy]benzimidazol-2-one. Grades: 95%. CAS No. 108929-47-1. Molecular formula: C13H19N3O3. Mole weight: 263.29. | |
| Cgp 13143 | Cgp 13143 is a bio-active chemical,but no detailed information has been published yet. Synonyms: Cgp 13143; Cgp13143; Cgp-13143. ((4-methyl-2-oxo-2H-1-benzopyran-6-yl)amino)oxo-Acetic acid. Grades: 98%. CAS No. 75919-69-6. Molecular formula: C12H9NO5. Mole weight: 247.21. | |
| Cgp 13231 | Cgp 13231 is the N-oxide metabolite of amocarzine. Synonyms: Cgp 13231; Cgp13231; Cgp-13231. 1-Piperazinecarbothioamide, 4-methyl-N-(4-((4-nitrophenyl)amino)phenyl)-4-oxide. Grades: 98%. CAS No. 113962-61-1. Molecular formula: C18H21N5O3S. Mole weight: 387.46. | |
| CGP 13501 | CGP 13501. Group: Biochemicals. Grades: Purified. CAS No. 56189-68-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| CGP 13501 | CGP 13501 is a positive allosteric modulator of GABAB receptors, potentiating the effects of GABA at this receptor type. Uses: Gaba-b receptor agonists. Synonyms: CGP13501; CGP 13501; CGP-13501; 3,5-bis(1,1-Dimethylethyl)-4-hydroxy-α,α-dimethylbenzenepropanal. Grades: ≥98% by HPLC. CAS No. 56189-68-5. Molecular formula: C19H30O2. Mole weight: 290.44. | |
| CGP-13501 | ?98% (HPLC), solid. Group: Fluorescence/luminescence spectroscopy. | |
| Cgp 15425 | Cgp 15425 is a bio-active chemical,but no detailed information has been published yet. Synonyms: Cgp 15425; Cgp15425; Cgp-15425. (S)-N1-((2S,5S,8R,11S,14S,17S)-8-((1H-indol-3-yl)methyl)-11-(4-aminobutyl)-5,17-dibenzyl-14-((R)-1-hydroxyethyl)-19-imino-3,6,9,12,15,18,22-heptaoxo-1-phenyl-4,7,10,13,16-pentaazadocosan-2-yl)-2-aminosuccinamide. Grades: 98%. CAS No. 76080-70-1. Molecular formula: C56H69N11O10. Mole weight: 1056.21. | |
| CGP-15720 hydrochloride | CGP-15720 is a antitumor agent. Uses: Antitumor. Synonyms: CGP-15720 hydrochloride; CGP-15720 HCl; CGP-15720A; CGP15720A; UNII-73G6V7978M. 4-(3-(2-(2-(pyridin-4-yl)-4,5-dihydro-1H-imidazol-1-yl)ethyl)ureido)benzoic acid hydrochloride. Grades: 98%. CAS No. 76692-12-1. Molecular formula: C18H20ClN5O3. Mole weight: 389.84. | |
| Cgp-17520 | Cgp-17520 is a new bio-active cephalosporin anti-biotic chemical comound synthesized by Ciba Geigy Ltd. Synonyms: Cgp 17520; Cgp-17520; Cgp17520. 7-(2-(4-(((2-Amino-2-carboxyethoxy)carbonyl)amino)phenyl)-2-hydroxyacetamido)-3-(((1-methyl-1H-tetrazol-5-yl)thio)methyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid sodium salt. Grades: >98 %. CAS No. 101706-66-5. Molecular formula: C22H24N8NaO9S2. Mole weight: 631.59. | |
| CGP-1758 monomethanesulfonate | CGP-1758 monomethanesulfonate is a new bio-active cephalosporin anti-biotic chemical comound synthesized by Ciba Geigy Ltd. Synonyms: CGP 1758B; CGP-1758B; CGP1758B. 2-Hydroxy-5- [2- [ [2-hydroxy-3- [4- (2-methoxyethoxy) phenoxy] propyl] amino] ethoxy] benzamide monomethanesulfonate;CGP1758 monomethanesulfonate. Grades: >98%. CAS No. 108289-44-7. Molecular formula: C22H32N2O10S. Mole weight: 516.56. | |
| Cgp 20309 | Cgp 20309 has a thiocarbonylamides structure and it is a potent antifilarial agent under laboratory research stage. Uses: Antifilarial agent. Synonyms: Cgp 20309; Cgp20309; Cgp-20309. N-(2-(1,1-dimethylethyl)-5-methoxy-6-benzothiazolyl)-4-methyl-1-Piperazinecarbothioamide. Grades: 98%. CAS No. 122378-48-7. Molecular formula: C18H26N4OS2. Mole weight: 378.56. | |
| CGP 20376 | CGP 20376 is a benzothiazole compound and it has antifilarial properties. Uses: Antifilarial agent. Synonyms: CGP 20376; CGP20376; CGP-20376. 3- ( ( ( (2- (1, 1-dimethylethyl) -5-methoxy-6-benzothiazolyl) amino) thioxomethyl) thio) -Propanoic acid;N-(2-tert-Butyl-5-methoxybenzothiazol-6-yl)dithiocarbonic acid 5-(1-carboxyethyl)ether. Grades: 98%. CAS No. 81059-04-3. Molecular formula: C16H20N2O3S3. Mole weight: 384.54. | |
| CGP-20712A methanesulfonate salt | solid, ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| CGP 20712 dihydrochloride | CGP 20712 dihydrochloride is a potent and selective β1-adrenoceptor antagonist (IC50 = 0.7 nM) with 10,000-fold selectivity over β2-adrenoceptors. Synonyms: CGP 20712A Dihydrochoride; CGP 20712ADihydrochoride; CGP 20712A; CGP20712A; CGP-20712A. SR-01000076208; 1-[2-((3-Carbamoyl-4-hydroxy)phenoxy)ethylamino]-3-[4-(1-methyl-4-trifluoromethyl-2-imidazolyl)phenoxy]-2-propanol dihydrochloride. Grades: ≥96% by HPLC. CAS No. 1216905-73-5. Molecular formula: C23H25F3N4O5.2HCl. Mole weight: 567.39. | |
| CGP 20712 dihydrochloride | CGP 20712 dihydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 1216905-73-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| CGP 20712 dihydrochloride | CGP 20712 dihydrochloride is a highly selective β1-adrenoceptor antagonist with an IC 50 of 0.7 nM. CGP 20712 dihydrochloride exhibits ~10,000-fold selectivity over β2-adrenoceptors [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1216905-73-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-101355A. | |
| Cgp 21833 | Cgp 21833 has a thiocarbonylamides structure and it is a potent antifilarial agent under laboratory research stage. Uses: Antifilarial agent. Synonyms: Cgp 21833; Cgp-21833; Cgp21833. 1-(2-(1,1-dimethylethyl)-5-methyl-6-benzothiazolyl)-2-methylhydrazide 1-Piperazinecarbothioic acid. Grades: 98%. CAS No. 122378-49-8. Molecular formula: C18H27N5S2. Mole weight: 377.57. | |
| CGP 23996 | CGP 23996 is a non-reducible somatostatin analog. It can be used for autoradiography. Uses: Autoradiography. Synonyms: CGP 23996; CGP23996; CGP-23996. BDBM82467; 2-Deamino-L-Abu(1)-L-Lys-L-Asp(NH2)-L-Phe-L-Phe-L-Trp-L-Lys-L-Thr-L-Tyr-L-Thr-L-Ser-L-Abu(1)-OH;(14R,20S,23R,26R,29R,32R)-2,17-bis(4-aminobutyl)-5-(2-amino-2-oxoethyl)-8,11-dibenzyl-20,26-bis[(1S)-1-hydroxyethyl]-29-(hydroxymethyl)-23-[(4-hydroxyphenyl)methyl]-14-(1H-indol-3-ylmethyl)-3,6,9,12,15,18,21,24,27,30,38-undecaoxo-1,4,7,10,13,16,19,22,25,28,31-undecazacyclooctatriacontane-32-carboxylic acid. Grades: 98%. CAS No. 86170-12-9. Molecular formula: C73H99N15O18. Mole weight: 1474.66. | |
| Cgp 29030A | This molecular is a piperazine derivative and its Pharmacological activity probablely is inhibition on nociceptive dorsal horn neurons that processed input from high-threshold mechanosensitive receptors in the skin and deep somatic tissues.It may be used to treat painful disorders which are complicated by increased motor. activity. Uses: Treat painful disorders. Synonyms: Cgp 29030A; Cgp29030A; Cgp-29030A. 1-p-chlorophenethyl-4-(3,5-dimethoxybenzoyl)piperazine hydrochloride. Grades: 98%. CAS No. 113240-27-0. Molecular formula: C21H26Cl2N2O3. Mole weight: 425.35. | |
| Cgp 29287 | Cgp 29287 is a renin inhibitor with a prolonged duration of action. Synonyms: CGP-29287; Z-Arg-Arg-Pro-Phe-His-Sta-Ile-His-Nepsilon-Boc-Lys methyl ester. Grades: 95%. CAS No. 93287-54-8. Molecular formula: C72H110N20O15. Mole weight: 1495.77. | |
| Cgp 31358 | CGP 31358 is a compound that can bind to a site on the N-methyl-D-aspartate (NMDA) receptor which is coupled to both the transmitter recognition site and the channel domain.It can be a tool for researching the molecular pharmacology of this receptor-channel complex. Uses: A tool for researching the molecular pharmacology of receptor-channel complex. Synonyms: Cgp 31358; Cgp-31358; Cgp31358; 1-(4-(1-(4-chlorophenyl)-1-methylethyl)-2-methoxyphenyl)-1H-1,2,4-Triazole-3-carboxamide. Grades: 98%. CAS No. 125652-47-3. Molecular formula: C19H19ClN4O2. Mole weight: 370.83. | |
| Cgp-33304 | Cgp-33304 is a dual phospholipase A2 inhibiting agent and leukotriene receptor antagonists. It may prevent hypoxia secondary to leukotriene induced bronchoconstriction in shock states. It has potential to be an useful therapeutic agent in acute ischemic disorders including traumatic shock. Uses: Cgp-33304 has potential to be an useful therapeutic agent in acute ischemic disorders including traumatic shock. Synonyms: Cgp 33304; Cgp33304; Cgp-33304; 1H-Tetrazole-5-carboxamide, N-(5-(3-(4-acetyl-3-hydroxy-2-propylphenox y)propoxy)-4-bromo-2-methylphenyl)-, monosodium salt;CGP33304;N-(3-(3-(4-Acetyl-3-hydroxy-2-n-propylphenoxy)propoxy)-4-bromo-6-methylphenyl)-1H-tetrazole-5-carboxamide sodium;Sodium 5-((5-(3-(4-acetyl-3-hydroxy-2-propylphenoxy)propoxy)-4-bromo-2-methylphenyl)carbamoyl)tetrazol-1-ide. Grades: >98%. CAS No. 111130-14-4. Molecular formula: C23H25BrN5NaO5. Mole weight: 554.38. | |
| CGP 3466B maleate | CGP 3466B maleate, a potent anti-apoptotic drug, is an orally active glyceraldehyde-3-phosphate dehydrogenase (GAPDH) inhibitor. CGP 3466B maleate was tested in clinical trials for its ability to help treat Parkinson's disease (PD) and amyotrophic lateral sclerosis (ALS) but the clinical trials have been terminated due to lack of benefit. Synonyms: N-(benzo[b][1]benzoxepin-5-ylmethyl)-N-methylprop-2-yn-1-amine;but-2-enedioic acid; Omigapil maleate; CGP 3466B; CGP-3466B; CGP3466B; TCH-346; TCH 346; TCH346; Omigapil maleate. Grades: >99 %. CAS No. 200189-97-5. Molecular formula: C23H21NO5. Mole weight: 391.42. | |
| CGP 3466B maleate | CGP 3466B maleate. Group: Biochemicals. Grades: Purified. CAS No. 200189-97-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| CGP35348 | CGP 35348 is a selective, brain penetrant, centrally active GABAB receptor antagonist with an EC 50 of 34 μM. CGP 35348 shows affinity for the GABAB receptor only [1]. CGP 35348 has a potential to improve neuromuscular coordination and spatial learning in albino mouse following neonatal brain damage [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 123690-79-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103530. | |
| CGP 35348 | CGP 35348 is a selective and brain penetrant GABAB receptor antagonist (IC50 = 34 μM as measured in rat cortical membranes) with higher affinity for postsynaptic than presynaptic receptors. Synonyms: CGP35348; CGP-35348; (3-Aminopropyl) (diethoxymethyl)phosphinic acid. CAS No. 123690-79-9. Molecular formula: C8H20NO4P. Mole weight: 225.22. | |
| CGP 35348 (GABAB Receptor Antagonist, CGP 35348, CGP35348, CGP-35348) | A selective antagonist of post-synaptic GABAB receptors (IC50 = 34uM) that can permeate the blood brain barrier. Exhibits about 10-fold lower affinity for pre-synaptic receptors. Blocks K+-evoked glycine exocytosis in mouse spinal cord and hippocampal nerve endings. Shown to antagonize the potentiating effect of L-baclofen on noradrenaline-induced stimulation of adenylate cyclase in rat cortex slices. Group: Biochemicals. Grades: Highly Purified. CAS No. 123690-79-9. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| CGP 35348 hydrate | ?97% (NMR), solid. Group: Fluorescence/luminescence spectroscopy. | |
| Cgp-35949 | Cgp-35949 is an LTD4 antagonist which has phospholipase inhibitory activity. It represents a new approach to the treatment of asthma. Uses: Cgp-35949 represents a new approach to the treatment of asthma. Synonyms: Cgp 35949; Cgp-35949; Cgp35949; 1H-Tetrazole-5-carboxamide, N-(5-(3-(4-acetyl-3-hydroxy-2-propylphenox y)propoxy)-4-chloro-2-methylphenyl)-, monosodium salt;CGP35949;N-(5-(3-(4-Acetyl-3-hydroxy-2-propylphenoxy)propoxy)-4-chloro-2-methylphenyl)-1H-tetrazole-5-carboxamide monosodium salt;Sodium N-[5-[3-(4-acetyl-3-hydroxy-2-propylphenoxy)propoxy]-4-chloro-2-methylphenyl]-1,2,3-triaza-4-azanidacyclopenta-2,5-diene-5-carboxamide;Sodium 5-((5-(3-(4-acetyl-3-hydroxy-2-propylphenoxy)propoxy)-4-chloro-2-methylphenyl)carbamoyl)tetrazol-1-ide. Grades: >98%. CAS No. 111130-13-3. Molecular formula: C23H25ClN5NaO5. Mole weight: 509.92. | |
| CGP 36216 | CGP 36216 hydrochloride is a selective GABAB antagonist that is active to presynaptic receptors but inactive to postsynaptic receptors. Synonyms: CGP 36216 hydrochloride; CGP36216 hydrochloride; CGP-36216 hydrochloride; (3-Aminopropyl)ethylphosphinic acid hydrochloride. Grades: ≥99% by HPLC. CAS No. 123691-29-2. Molecular formula: C5H14NO2P. Mole weight: 151.14. | |
| CGP 36216 hydrochloride | CGP 36216 is a selective GABA antagonist with IC50 of 43 μM, which is active at the presynaptic but not postsynaptic. Synonyms: CGP 36216. Grades: ≥98%. CAS No. 1781834-71-6. Molecular formula: C5H14NO2P·HCl. Mole weight: 187.6. | |
| CGP 36216 hydrochloride | CGP 36216 hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 123691-29-2. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| CGP36742 | ?97% (NMR). Group: Fluorescence/luminescence spectroscopy. | |
| CGP 37157 | CGP 37157. Group: Biochemicals. Grades: Purified. CAS No. 75450-34-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| CGP 37157 | CGP 37157 is a a selective sodium-calcium exchanger inhibitor with IC50 value of 0.36 μM in isolated mitochondria. It does not affect channels, exchangers, or ATPases on the cardiac sarcolemma or ATPases on sarcoplasmic reticulum. CGP 37157 can be used to study the role of mitochondrial-derived calcium in cytoplasmic calcium homeostasis. Synonyms: Cgp 37157; Cgp-37157; Cgp37157. 7-Chloro-5-(2-chlorophenyl)-1,5-dihydro-4,1-benzothiazepin-2(3H)-one. Grades: 98%. CAS No. 75450-34-9. Molecular formula: C15H11Cl2NOS. Mole weight: 289.78. | |
| CGP-37157 | ?98% (HPLC), powder. Group: Fluorescence/luminescence spectroscopy. | |
| CGP-37157 - CAS 75450-34-9 | A cell-permeable benzothiazepine derivative of clonazepam that acts as a specific and potent inhibitor of the mitochondrial Na+/Ca2+ exchanger (IC?? = 360 nM). Group: Fluorescence/luminescence spectroscopy. | |
| CGP 37849 | CGP 37849 is a potent, competitive and orally active N-methyl-D-aspartate (NMDA) receptor antagonist. CGP 37849 is an anticonvulsant in rodents and has antidepressant and anxiolytic-like effects [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 127910-31-0. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-107702. | |
| CGP 37849 | CGP 37849 is a potent, selective and competitive NMDA receptor antagonist (Ki = 35 nM). CGP 37849 exhibits an anticonvulsant effect following oral administration in vivo. Synonyms: CGP37849; CGP 37849; CGP-37849; (E)-(±)-2-Amino-4-methyl-5-phosphono-3-pentenoic acid. Grades: ≥99% by HPLC. CAS No. 127910-31-0. Molecular formula: C6H12NO5P. Mole weight: 209.14. | |
| CGP 37849 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| CGP 37849 | CGP 37849. Group: Biochemicals. Grades: Purified. CAS No. 127910-31-0. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| CGP 37849 ((E)-(±)-2-Amino-4-methyl-5-phosphono-3-pentenoic Acid) | A highly potent competitive antagonist selective fornMDA receptors (Ki = 35nM). Biologically viable admitted orally or systematically. Widely used in studies of epilepsy, schizophrenia, depression, stress and anxiety related mental disorders. Group: Biochemicals. Grades: Highly Purified. CAS No. 127910-31-0. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Cgp 38560 | Cgp 38560 is a potent renin inhibitor and it can induce a dose-dependent decrease in angiotensin II and plasma renin activity and a long-lasting and dose-dependent rise in active renin. Although reduction of plasma renin activity to unmeasurable levels, the doses used did not reduce plasma angiotensin II maximally. Synonyms: Cgp 38560; Cgp38560; Cgp-38560. (R)-N-(2-(((1,1-dimethylethyl)sulfonyl)methyl)-1-oxo-3-phenylpropyl)-L-histidyl-3-cyclohexyl-L-alanyl-N-butyl-L-Valinamide monomethanesulfonate. Grades: 98%. CAS No. 122088-76-0. Molecular formula: C39H64N6O9S2. Mole weight: 825.09. | |
| CGP 39551 | Cgp 39551 is a selective and competitive N-methyl-D-aspartate (NMDA) receptor antagonist originated by Novartis. Ki is 310 nM for inhibition of [3H]-CPP binding in rat brain. CGP 39551 produces excitatory effects and causes psychotomimetic effects in humans. Treatment for Craniocerebral trauma, Epilepsy and Stroke was discontinued. Uses: Craniocerebral trauma, epilepsy and stroke. Synonyms: Cgp 39551; Cgp39551; Cgp-39551; (E)-(+/-)-2-Amino-4-methyl-5-phosphono-3-pentenoic acid ethyl ester;CGP 39551;(E)-(-)-2-amino-4-methyl-5-phosphono-3-pentenoic acid ethyl ester. Grades: 98%. CAS No. 127910-32-1. Molecular formula: C8H16NO5P. Mole weight: 237.19. | |
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