A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
ABC-type (ATP-binding cassette-type) ATPase, characterized by the presence of two similar ATP-binding domains. Does not undergo phosphorylation during the transport process. Enzymes of Gram-negative bacteria that export lipo-oligosaccharides and lipopolysaccharides. Group: Enzymes. Enzyme Commission Number: EC 7.5.2.5 (Formerly EC 3.6.3.39). Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4677; lipopolysaccharide-transporting ATPase; EC 3.6.3.39. Cat No: EXWM-4677.
lipoprotein lipase
Hydrolyses triacylglycerols in chylomicrons and low-density lipoproteins. Also hydrolyses diacylglycerol. Group: Enzymes. Synonyms: clearing factor lipase; diglyceride lipase; diacylglycerol lipase; postheparin esterase; diglyceride lipase; postheparin lipase; diacylglycerol hydrolase; lipemia-clearing factor. Enzyme Commission Number: EC 3.1.1.34. CAS No. 9004-2-8. LPL. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3460; lipoprotein lipase; EC 3.1.1.34; 9004-02-8; clearing factor lipase; diglyceride lipase; diacylglycerol lipase; postheparin esterase; diglyceride lipase; postheparin lipase; diacylglycerol hydrolase; lipemia-clearing factor. Cat No: EXWM-3460.
Liposidolide A
It is produced by the strain of Str. sp. RS-28. It's a macrolide antibiotic. It is resistant to plant pathogenic fungi and algae. Molecular formula: C78H138O30. Mole weight: 1555.91.
Liposidomycin A
It is produced by the strain of Str. sp. SN-1061M. It has antibacterial effect, but the antibacterial activity is weak. It has strong inhibition of mycobacteria (MIC is 0.16 μg/mL). It has the function of inhibiting glycopeptide biosynthesis, and can inhibit the glycopeptide biosynthesis of Escherichia coli with IC50 of 0.03 μg/mL. Molecular formula: C44H67N5O21S. Mole weight: 1034.09.
Liposidomycin B
It is produced by the strain of Str. sp. SN-1061M. It has antibacterial effect, but the antibacterial activity is weak. It has strong inhibition of mycobacteria (MIC is 0.16 μg/mL). It has the function of inhibiting glycopeptide biosynthesis, and can inhibit the glycopeptide biosynthesis of Escherichia coli with IC50 of 0.03 μg/mL. Molecular formula: C42H67N5O21S. Mole weight: 1010.06.
Liposidomycin C
It is produced by the strain of Str. sp. SN-1061M. It has antibacterial effect, but the antibacterial activity is weak. It has strong inhibition of mycobacteria (MIC is 0.16 μg/mL). It has the function of inhibiting glycopeptide biosynthesis, and can inhibit the glycopeptide biosynthesis of Escherichia coli with IC50 of 0.03 μg/mL. Molecular formula: C42H67N5O21S. Mole weight: 1010.06.
Lipoteichoic acid
Lipoteichoic acid is an orally effect anti-inflammatory and antitumor agent. Lipoteichoic acid is a crucial immune molecule in Gram-positive bacteria that activates the complement system by inducing C3 and inhibiting CD55. Lipoteichoic acid regulates macrophage autophagy through the PI3K/Akt/mTOR pathway. Lipoteichoic acid induces lung damage in mice. Lipoteichoic acid inhibits the production of melanin [1] [2] [3] [4] [5] [6] [7]. Uses: Scientific research. Group: Natural products. CAS No. 56411-57-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-N9481.
Lipoxidase
100mg Pack Size. Group: Biochemicals, Research Organics & Inorganics. Formula: N/A. CAS No. 9029-60-1. Prepack ID 14946502-100mg. See USA prepack pricing.
Lipoxin A4
Lipoxin A4 (LXA4), an endogenous lipoxygenase-derived eicosanoid mediator, has potent dual pro-resolving and anti-inflammatory properties [1]. Lipoxin A4 inhibits proliferation and inflammatory cytokine/chemokine production of human epidermal keratinocytes (NHEKs) associated with the ERK1/2 and NF-kB pathways [2]. Lipoxin A4 inhibits serum amyloid A (SAA)-mediated IL-8 release with an IC 50 value of 25.74 nM [3]. Uses: Scientific research. Group: Natural products. Alternative Names: LXA4. CAS No. 89663-86-5. Pack Sizes: 25 μg (283.71 μM * 250 μL in Ethanol). Product ID: HY-113509.
Heterocyclic Organic Compound. Alternative Names: Lipoxin A5, CTK8E7281, 110657-98-2. CAS No. 110657-98-2. Molecular formula: C20H30O5. Mole weight: 350.45. Appearance: A solution in ethanol. Purity: 0.96. IUPACName: (5S,6S,15S)-5,6,15-trihydroxyicosa-7,9,11,13,17-pentaenoic acid. Canonical SMILES: CC/C=C\\C[C@@H] (/C=C\\C=C/C=C/C=C/[C@@H] ([C@H] (CCCC (=O)O)O)O)O. Catalog: ACM110657982.
lipoyl amidotransferase
In the bacterium Listeria monocytogenes the enzyme takes part in a pathway for scavenging of lipoic acid. The enzyme is bound to 2-oxo-acid dehydrogenases such as the pyruvate dehydrogenase complex, where it transfers the lipoyl moiety from lipoyl-[glycine cleavage system H] to the E2 subunits of the complexes. Group: Enzymes. Synonyms: LipL (gene name, ambiguous). Enzyme Commission Number: EC 2.3.1.200. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2145; lipoyl amidotransferase; EC 2.3.1.200; LipL (gene name, ambiguous). Cat No: EXWM-2145.
lipoyl(octanoyl) transferase
This is the first committed step in the biosynthesis of lipoyl cofactor. Lipoylation is essential for the function of several key enzymes involved in oxidative metabolism, as it converts apoprotein into the biologically active holoprotein. Examples of such lipoylated proteins include pyruvate dehydrogenase (E2 domain), 2-oxoglutarate dehydrogenase (E2 domain), the branched-chain 2-oxoacid dehydrogenases and the glycine cleavage system (H protein). Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the true substrate. The other enzyme involved in the biosynthesis of lipoyl cofactor is EC 2.8.1.8, lipoyl synthase. An alternative lipoylation pathway invol...rase; octanoyl-[acyl-carrier-protein]:protein N-octanoyltransferase. Enzyme Commission Number: EC 2.3.1.181. CAS No. 392687-64-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2123; lipoyl(octanoyl) transferase; EC 2.3.1.181; 392687-64-8; LipB; lipoyl (octanoyl)-[acyl-carrier-protein]-protein N-lipoyltransferase; lipoyl (octanoyl)-acyl carrier protein:protein transferase; lipoate/octanoate transferase; lipoyltransferase; octanoyl-[acyl carrier protein]-protein N-octanoyltransferase; lipoyl(octanoyl)transferase; octanoyl-[acyl-carrier-protein]:protein N-octanoyltransferase. Cat No: EXWM-2123.
lipoyl synthase
This enzyme is a member of the 'AdoMet radical' (radical SAM) family, all members of which produce the 5'-deoxyadenosin-5'-yl radical and methionine from AdoMet [i.e. S-adenosylmethionine, or S-(5'-deoxyadenosin-5'-yl)methionine], by the addition of an electron from an iron-sulfur centre. The radical is converted into 5'-deoxyadenosine when it abstracts a hydrogen atom from C-6 and C-8, leaving reactive radicals at these positions so that they can add sulfur, with inversion of configuration. This enzyme catalyses the final step in the de-novo biosynthesis of the lipoyl cofactor, with the other enzyme involved being EC 2.3.1.181, lipoyl(octanoyl) transferase. Lipoylation is essential ...pathway involves EC 2.7.7.63, lipoate-protein ligase, which can lipoylate apoproteins using exogenous lipoic acid (or its analogues). Group: Enzymes. Synonyms: LS; LipA; lipoate synthase; protein 6-N-(octanoyl)lysine:sulfur sulfurtransferase; protein N6-(octanoyl)lysine:sulfur sulfurtransferase. Enzyme Commission Number: EC 2.8.1.8. CAS No. 189398-80-9. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3366; lipoyl synthase; EC 2.8.1.8; 189398-80-9; LS; LipA; lipoate synthase; protein 6-N-(octanoyl)lysine:sulfur sulfurtransferase; protein N6-(octanoyl)lysine:sulfur sulfurtransferase. Cat No: EXWM-3366.
Liproxstatin-1 is a potent ferroptosis inhibitor. Grades: >98%. CAS No. 950455-15-9. Molecular formula: C19H21ClN4. Mole weight: 340.85.
Liproxstatin-1 hydrochloride
Liproxstatin-1 is a potent inhibitor of ferroptosis, a form of regulated necrosis associated with the iron-dependent accumulation of lipid hydroperoxides. Synonyms: N-[(3-Chlorophenyl)methyl]spiro[piperidine-4,2'(1'H)-quinoxalin]-3'-amine hydrochloride. Grades: ≥98% by HPLC. CAS No. 2250025-95-5. Molecular formula: C19H21ClN4·HCl. Mole weight: 377.31.
Lipstatin
Lipstatin, a potent inhibitor of the pancreas lipase, is reported to be useful in the treatment and/or prevention of obesity and related diseases. Group: Biochemicals. Alternative Names: N-Formyl-L-leucine (1S,3Z,6Z)-1-[[(2S,3S)-3-Hexyl-4-oxo-2-oxetanyl]methyl]-3,6-dodecadien-1-yl Ester; N-Formyl-L-leucine [2S-[2α(1R*,3Z,6Z),3 β]]-. Grades: Highly Purified. CAS No. 96829-59-3. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
Lipstatin
Lipstatin is a pancreatic lipase inhibitor ( IC 50 =0.14 μM), whose structure is closely related to the known inhibitor, Esterastin. Lipstatin inhibits the absorption of triglycerides without affecting the absorption of oleic acid. Lipstatin has no inhibitory effects on other pancreatic enzymes, such as phospholipase A2 and trypsin (<200 μM) [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 96829-59-3. Pack Sizes: 10 mM * 1 mL; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N2330.
Lipstatin
Lipstatin, a potent inhibitor of the pancreas lipase, is reported to be useful in the treatment and prevention of obesity and related diseases. It is a natural product that was first isolated from Actinobacterium Streptomyces toxytricini. Synonyms: N-Formyl-L-leucine (1S,3Z,6Z)-1-[[(2S,3S)-3-Hexyl-4-oxo-2-oxetanyl]methyl]-3,6-dodecadien-1-yl Ester; N-Formyl-L-leucine [2S-[2α(1R*,3Z,6Z),3β]]-1-[(3-Hexyl-4-oxo-2-oxetanyl)methyl]-3,6-dodecadienyl Ester; (-)-Lipstatin. Grades: >95%. CAS No. 96829-59-3. Molecular formula: C29H49NO5. Mole weight: 491.70.
Liq
Electron transport and hole blocking material in organic light emitting diodes (OLED). Group: Organic light-emitting diode (oled) materials. Alternative Names: (8-Hydroxyquinolinato)lithium,(8-Quinolinolato)lithium,8-Hydroxyquinoline lithium. CAS No. 25387-93-3. Product ID: lithium; quinolin-8-olate. Molecular formula: 151.09. Mole weight: C9H6LiNO. [Li+].C1=CC2=C(C(=C1)[O-])N=CC=C2. 1S/C9H7NO. Li/c11-8-5-1-3-7-4-2-6-10-9(7)8; /h1-6, 11H; /q; +1/p-1, FQHFBFXXYOQXMN-UHFFFAOYSA-M. FQHFBFXXYOQXMN-UHFFFAOYSA-M.
Liquidambaric acid (Betulonic acid). Group: Biochemicals. Alternative Names: Betulonic acid. Grades: Plant Grade. CAS No. 4481-62-3. Pack Sizes: 20mg. Molecular Formula: C30H46O3, Molecular Weight: 454.684. US Biological Life Sciences.
Worldwide
Liquidambaric lactone
Liquidambaric lactone. Group: Biochemicals. Alternative Names: 11,12-Epoxy-3-oxo-28,13-oleananolide. Grades: Plant Grade. CAS No. 185051-75-6. Pack Sizes: 10mg. Molecular Formula: C30H44O4, Molecular Weight: 468.668. US Biological Life Sciences.
Worldwide
Liquid Chlorine
Cas No. -7782-50-5.
Liquid crystal mixture E7
Synonyms: [1,1':4',1''-Terphenyl]-4-carbonitrile, 4''-pentyl-, mixt. with 4'-heptyl[1,1'-biphenyl]-4-carbonitrile, 4'-(octyloxy)[1,1'-biphenyl]-4-carbonitrile and 4'-pentyl[1,1'-biphenyl]-4-carbonitrile; 4''-Pentyl-[1,1':4',1''-terphenyl]-4-carbonitrile compound with 4'-(octyloxy)-[1,1'-biphenyl]-4-carbonitrile and 4'-heptyl-[1,1'-biphenyl]-4-carbonitrile and 4'-pentyl-[1,1'-biphenyl]-4-carbonitrile; [1,1'-Biphenyl]-4-carbonitrile, 4'-(octyloxy)-, mixt. contg.; [1,1'-Biphenyl]-4-carbonitrile, 4'-heptyl-, mixt. contg.; [1,1'-Biphenyl]-4-carbonitrile, 4'-pentyl-, mixt. contg.; BDH Liquid Crystal E 7; BDH-E 7; BL 001; E 20 (liquid crystal); E 7 (liquid crystal); GR 63; Licrilite E 7; Lixon GR 63; Merck E 7; Merck NLC-E7; Ro TN 570. Grades: 99.5% (5CB:7CB:8OCB:5CT=51:25:16:8). CAS No. 63748-28-7. Molecular formula: C24H23N.C21H25NO.C20H23N.C18H19N. Mole weight: 1159.63.
Liquid Crystal, TK-LQ 2040, Electric effect type, Mesomorphic range:20-40deg C [Nematic Liquid Crystal]
Liquid Crystal, TK-LQ 2040, Electric effect type, Mesomorphic range:20-40deg C [Nematic Liquid Crystal]. Group: Liquid crystal (lc) building blocks.
Liquid Crystal, TK-LQ 3858, Electric effect type, Mesomorphic range:38-58deg C [Nematic Liquid Crystal]
Liquid Crystal, TK-LQ 3858, Electric effect type, Mesomorphic range:38-58deg C [Nematic Liquid Crystal]. Group: Liquid crystal (lc) building blocks.
Liquid Paraffin
Liquid Paraffin can be used as a lubricant. Synonyms: Delphinidin; Paraffin Oil; Ephdine. CAS No. 8012-95-1. Molecular formula: C15H11ClO7. Mole weight: 338.69.
Liqui-Nox Detergent, 3.8L
Health Risk: Moderate. Notes: Biodegradable, phosphate-free, interfering residue free; use as 1% solution. For manual use only (i. e. not for dishwasher use). Grades: chem-grade laboratory. Product ID: 872512. -- SOLD FOR EDUCATIONAL USE ONLY --
Liquiritigenin
Liquiritigenin, a flavanone isolated from Glycyrrhiza uralensis , is a highly selective estrogen receptor β ( ERβ ) agonist with an EC 50 of 36.5 nM for activation of the ERE tk-Luc. Uses: Scientific research. Group: Natural products. Alternative Names: 4',7-Dihydroxyflavanone. CAS No. 578-86-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-N0377.
Liquiritigenin
Liquiritigenin - Product ID: NST-10-173. Category: Flavonoids. Alternative Names: (2S)-Liquiritigenin, 4?,7-Dihydroxyflavanone, Menerba. Purity: 85%. Test method: HPLC. CAS No. 578-86-9. Pack Sizes: 0,05g, 0,1g, 0,25g, 0,5g. Appearance: White Powder. Molecular formula: C15H12O4. Mole weight: 256.25. Storage: +2 +8 °C.
Liquiritigenin
Liquiritigenin. Group: Biochemicals. Grades: Purified. CAS No. 578-86-9. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
Liquiritin
Liquiritin. Group: Biochemicals. Alternative Names: Liquiritoside. Grades: Plant Grade. CAS No. 551-15-5. Pack Sizes: 20mg. Molecular Formula: C21H22O9, Molecular Weight: 418.394. US Biological Life Sciences.
Worldwide
Liquiritin
Liquiritin, a flavonoid isolated from Glycyrrhiza uralensis , is a potent and competitive AKR1C1 inhibitor with IC 50 s of 0.62 μM, 0.61 μM, and 3.72μM for AKR1C1, AKR1C2 and AKR1C3, respectively. Liquiritin efficiently inhibits progesterone metabolism mediated by AKR1C1 in vivo [1]. Liquiritin acts as an antioxidant and has neuroprotective, anti-cancer and anti-inflammatory activity [2]. Uses: Scientific research. Group: Natural products. CAS No. 551-15-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0376.
Liquiritin apioside
Liquiritin apioside. Group: Biochemicals. Grades: Plant Grade. CAS No. 74639-14-8. Pack Sizes: 10mg. Molecular Formula: C26H30O13, Molecular Weight: 550.51. US Biological Life Sciences.
Worldwide
Lirafugratinib
Lirafugratinib (RLY-4008) is an orally active, irreversible and highly selective FGFR2 inhibitor with an IC 50 of 3 nM. Lirafugratinib covalently binds to Cys491. Lirafugratinib targets FGFR2 primary alterations and resistance mutations and induces tumor regression while sparing other FGFRs [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: RLY-4008. CAS No. 2549174-42-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-147250.
Lirafugratinib hydrochloride
Lirafugratinib (RLY-4008) hydrochloride is an orally active, irreversible and highly selective FGFR2 inhibitor with an IC 50 of 3 nM. Lirafugratinib hydrochloride covalently binds to Cys491. Lirafugratinib hydrochloride targets FGFR2 primary alterations and resistance mutations and induces tumor regression while sparing other FGFRs [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: RLY-4008 hydrochloride. CAS No. 2688040-45-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-147250A.
Liraglutide
Liraglutide is a glucagon-like peptide-1 ( GLP-1 ) receptor agonist used clinically to treat type 2 diabetes mellitus. Uses: Scientific research. Group: Peptides. CAS No. 204656-20-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P0014.
Liraglutide is the long-acting analogue of glucagon-like peptide-1 (GLP-1) receptor which could protect b-cells from apoptosis under conditions associated with the development of type 1 and type 2 diabetes. Synonyms: L-Histidyl-L-alanyl-L-α-glutamylglycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-α-aspartyl-L-valyl-L-seryl-L-seryl-L-tyrosyl-L-leucyl-L-α-glutamylglycyl-L-glutaminyl-L-alanyl-L-alanyl-N6-[N-(1-oxohexadecyl)-L-γ-glutamyl]-L-lysyl-L-α-glutamyl-L-pheny. Grades: > 95%. CAS No. 204656-20-2. Molecular formula: C172H265N43O51. Mole weight: 3751.20.
A squalene epoxidase inhibitor. Used as an antifungal. Group: Biochemicals. Alternative Names: (6-Methoxy-2-pyridinyl)-methylcarbamothioic Acid O-(5,6,7,8-Tetrahydro-2-naphthalenyl) Ester, Piritetrate, M-732, Zefnart. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
Liranaftate
Liranaftate is a squalene epoxidase inhibitor exhabing anti-fungicidal activities. Synonyms: Liranaftate; M-732; M 732; M732; Piritetrate. Grades: >98%. CAS No. 88678-31-3. Molecular formula: C18H20N2O2S. Mole weight: 328.43.
Liranaftate
Liranaphthyl ester is a new third-generation thiocarbamate antifungal drug, which is a new class III chemical drug. Synonyms: LNF; O- (5, 6, 7, 8-tetrahydronaphthalen-2-yl) N- (6-methoxypyridin-2-yl) -N-methylcarbamothioate; carbamothioicacid, (6-methoxy-2-pyridinyl) methyl-, o- (5, 6, 7, 8-Chemicalbooktetrahydro-2-na; phthalenyl) ester; LIRANAFATE; LIRANAFTATE; M-732; (6-METHOXY-2-PYRIDINYL) -METHYLCARBAMOTHIOICACIDO- (5, 6, 7, 8-TETRAHYDRO-2-NAPHTHALENYL) ESTER. CAS No. 88678-31-3. Product ID: PAP-0051. Molecular formula: C18H20N2O2S. Category: Anti-Infectives. Product Keywords: Antibacterial, Anti-inflammatory and Antiviral Series; Liranaftate; PAP-0051; Anti-Infectives; C18H20N2O2S; 88678-31-3. Appearance: Off-White Solid. Standard: CP. Chemical Name: O-(5,6,7,8-tetrahydronaphthalen-2-yl) N-(6-methoxypyridin-2-yl)-N-methylcarbamothioate. Grade: Pharmaceutical Grade. Source and Preparation: The reaction of 5, 6, 7, 8-tetrahydro-2-naphthol with thiophosgene produced 5, 6, 7, 8-tetrahydro-2-naphthol ester and 2-methoxy-6-methylamine base pyridine in isopropyl alcohol and water for 2 hours at room temperature to obtain Liranaphthol. The total yield was 70%. Solubility: DMSO (Slightly), Methanol (Slightly, Heated). Storage: Keep in dark place,Sealed in dry,Room Temperature. Applications: Broad-spectrum antifungal agents. Boiling Point: 462.5±55.0 °C(Predicted). Melting Point: 98.5-99.5°C. Density: 1.240±0.06 g/cm3(Predicted). Product Description:
Liranaftate
Liranaftate (Piritetrate) is a squalene epoxidase inhibitor with anti-fungicidal activities. Liranaftate can be used for the research of dermatophytes. Liranaftate also suppresses fungal element-promoted production of IL-8 and experimental inflammation [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Piritetrate; M-732. CAS No. 88678-31-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-B0348.
Liranaftate
Liranaftate. Group: Biochemicals. Alternative Names: (6-Methoxy-2-pyridinyl)-methylcarbamothioic acid; O-(5,6,7,8-Tetrahydro-2-naphthyl) N-(6-methoxy-2-pyridyl)-N-methylthiocarbamate; Piritetrate, M-732, zefnart. Grades: Highly Purified. CAS No. 88678-31-3. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C18H20N2O2S. US Biological Life Sciences.
Worldwide
Lirentelimab
Lirentelimab (AK002) is a humanized IgG1 monoclonal antibody that targets sialic acid-binding Ig-like lectin 8 ( SIGLEC8 ). Lirentelimab induces cell apoptosis of IL-5-activated eosinophils and inhibits IgE-mediated mast cell activation. Lirentelimab can be used for the research of eosinophilic gastritis and duodenitis [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: AK002; Antolimab. CAS No. 2283348-97-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99371.
Lirilumab
Lirilumab (IPH2102) is an anti-KIR monoclonal antibody, and shows antitumor activity. Lirilumab can be used in Leukemia, squamous cell carcinoma of the head and neck (SCCHN) research [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: IPH2102. CAS No. 1000676-41-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99208.
Lirilumab
A fully humanized monoclonal antibody against killer-cell immunoglobulin-like receptors (KIR), with potential immune checkpoint inhibitory and antineoplastic activities. Upon administration, lirilumab binds to KIR, thereby preventing the binding of KIR ligands to KIR on natural killer (NK) cells. By blocking these inhibitory receptors, NK cells become activated and attack cancer cells leading to tumor cell death. KIR, a member of the immunoglobulin superfamily, is expressed on the surface of NK cells. Synonyms: Anti-KIR (1-7F9); Anti-KIR monoclonal antibody - Innate Pharma; BMS-986015; BMS 986015; BMS986015; IPH-21; IPH 21; IPH21; IPH-2101; IPH2102; IPH 2102;LIRI; NN 1975; NN1975; NN-1975. CAS No. 1000676-41-4.
Liriodenine
Liriodenine (Spermatheridine; VLT045) is an aporphine alkaloid isolated from the plant Mitrephora sirikitiae and has anti-cancer activities [1]. Liriodenine induces cell apoptosis , activates the intrinsic pathway by induction of caspase-3 and caspase-9 [2]. Uses: Scientific research. Group: Natural products. Alternative Names: Spermatheridine; VLT045. CAS No. 475-75-2. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N3376.
Liriope muscari baily saponins C
Liriope muscari baily saponins C. Group: Biochemicals. Grades: Plant Grade. CAS No. 87480-46-4. Pack Sizes: 20mg. Molecular Formula: C44H70O16, Molecular Weight: 855.02. US Biological Life Sciences.
Worldwide
Liriopeside B
Liriopeside B. Group: Biochemicals. CAS No. 87425-34-1. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
Liriopesides B
Liriopesides B (Nolinospiroside F) is a steroidal saponin isolated from Ophiopogon japonicas. Liriopesides B has anti-oxidative and anti-aging effects [1]. Uses: Scientific research. Group: Natural products. Alternative Names: Nolinospiroside F. CAS No. 87425-34-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N5135.
Liriopesides B
Liriopesides B. Group: Biochemicals. Grades: Plant Grade. CAS No. 87425-34-1. Pack Sizes: 10mg. Molecular Formula: C39H62O12, Molecular Weight: 722.91. US Biological Life Sciences.
Worldwide
Lirioprolioside B
Lirioprolioside B. Group: Biochemicals. Grades: Plant Grade. CAS No. 182284-68-0. Pack Sizes: 10mg. Molecular Formula: C41H64O13, Molecular Weight: 764.94. US Biological Life Sciences.
Worldwide
Lirioresinol-B dimethyl ether
It is extracted from the seeds of Magnolia fargesii CHENG (Magnoliaceae). It inhibits NF-κB and COX-2 and activates IκBα expression in CCl4-induced hepatic fibrosis. It has anti-inflammatory and anti-cancer activities against HepG2 cells as well as in BALB/C male mice. Synonyms: NSC 83441; 1,4-bis(3,4,5-trimethoxyphenyl)tetrahydro-1H,3H-furo[3,4-c]furan; Lirioresinol B, O,O-dimethyl-; (+)-O,O-Dimethyl lirioresinol-B; Syringaresinol dimethyl ether; Lirioresinol B dimethyl ether. CAS No. 80780-43-4. Molecular formula: C24H30O8. Mole weight: 446.49.
Lisaftoclax
Lisaftoclax (compound 6) is a dual Bcl-2 and Bcl-xl inhibitor with anti-tumor activity, extracted from patent WO2018027097A1. Lisaftoclax exhibits IC 50 values of 2 nM and 5.9 nM for Bcl-2 and Bcl-xl, respectively [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: APG-2575; Bcl-2/Bcl-xl inhibitor 1. CAS No. 2180923-05-9. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-129179.