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| Product | Description | |
|---|---|---|
| NVP-2 | NVP-2 is a potent and selective ATP-competitive cyclin dependent kinase 9 (CDK9) probe, inhibits CDK9/CycT activity with an IC50 of 0.514 nM. NVP-2 displays inhibitory effcts on CDK1/CycB, CDK2/CycA and CDK16/CycY kinases with IC50 values of 0.584 ?M, 0.706 ?M, and 0.605 ?M, respectively. NVP-2 induces cell apoptosis.[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1263373-43-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12214A. |  |
| NVP 231 | NVP 231. Group: Biochemicals. Grades: Purified. CAS No. 362003-83-6. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. |  Worldwide |
| NVP 231 | NVP 231 is a potent, specific, and reversible ceramide kinase (CerK) inhibitor(IC50=12 nM) that competitively inhibits binding of ceramide to CerK[1]. NVP 231 induces cell apoptosis by increasing DNA fragmentation and caspase-3 and caspase-9 cleavage[2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 362003-83-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-13945. | |
| NVP-231 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. |  |
| NVP-231 | NVP-231. Group: Biochemicals. Alternative Names: N-[2-(Benzoylamino)-6-benzothiazolyl]-tricyclo[3.3.1.13, 7]decane-1-carboxamide; NVP 231. Grades: Highly Purified. CAS No. 362003-83-6. Pack Sizes: 10mg. Molecular Formula: C25H25N3O2S, Molecular Weight: 431.55. US Biological Life Sciences. | Worldwide |
| NVP-AAM077 Tetrasodium Hydrate (NVP-AAM077, [[[ (1S) -1- (4-Bromophenyl) ethyl]amino] (1, 2, 3, 4-tetrahydro-2, 3-dioxo-5-quinoxalinyl) methyl] Phosphonic Acid Tetrasodium Hydrate, PEAQX Tetrasodium Hydrate, NMDA Antagonist VII) | A potent antagonist for NMDA receptors. Modestly higher selectivity for the NR2A than for the NR2B containing NMDA receptors (IC50 = 0.015 and 0.078uM) but insufficient to discriminate between NR2A and NR2B-containing NMDA receptors. Widely used for researches in synaptic plastic, learning and memory, and epilepsy. Group: Biochemicals. Grades: Highly Purified. CAS No. 459836-30-7. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| NVP ADW 742 | NVP ADW 742. Group: Biochemicals. Grades: Purified. CAS No. 475488-23-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| NVP-ADW742 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| NVP-AEW541 | NVP-AEW541 (AEW541 ) is an orally active inhibitor of the insulin-like growth factor 1 receptor (IGF-1R) with an IC50 value of 0.15 ?M. NVP-AEW541 also inhibits InsR, IC50 with a value of 0.14 ?M. NVP-AEW541 has antitumor activity[1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AEW541. CAS No. 475489-16-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-50866. | |
| NVP-AUY 922 | NVP-AUY 922 is a potent inhibitor of heat shock protein 90 (Hsp90) that prevents the proliferation of a range of human cancer cell lines. NVP-AUY 922 has been shown to enhance the radiation sensitivity of tumor cell lines under hypoxia. Group: Biochemicals. Alternative Names: 5-[2, 4-Dihydroxy-5- (1-methylethyl) phenyl]-N-ethyl-4-[4- (4-morpholinylmethyl) phenyl]-3-isoxazolecarboxamide; VER 52296; NVP-AUY922. Grades: Highly Purified. CAS No. 747412-49-3. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| NVP-BAG956 | NVP-BAG956. Group: Biochemicals. Alternative Names: 2-Methyl-2- [4- [2-methyl-8- [ (pyridin-3-yl) ethynyl] imidazo [4, 5-c] quinolin-1-yl] phenyl] propionitrile; BAG 956; NVP-BAG 956; α , α -Dimethyl-4- [2-methyl-8- (3-pyridinylethynyl) -1H-imidazo [4, 5-c] quinolin-1-yl] benzeneacetonitrile. Grades: Highly Purified. CAS No. 853910-02-8. Pack Sizes: 10mg. Molecular Formula: C28H21N5, Molecular Weight: 427.5. US Biological Life Sciences. | Worldwide |
| NVP-BEZ 235 | Inhibitor of phosphatidylinositol 3-kinases, P13K and mTOR. Group: Biochemicals. Alternative Names: 4-[2,3-Dihydro-3-methyl-2-oxo-8-(3-quinolinyl)-1H-imidazo[4,5-c]quinolin-1-yl]-α,α-dimethyl-benzeneacetonitrile; 2-Methyl-2- [4- [3-methyl-2-oxo-8- (quinolin-3-yl) -2, 3-dihydroimidazo [4, 5-c] quinolin-1-yl] phenyl] propionitrile; BEZ 235. Grades: Highly Purified. CAS No. 915019-65-7. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| NVP BHG 712 | NVP BHG 712. Group: Biochemicals. Grades: Purified. CAS No. 940310-85-0. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| NVP-BHG712 | NVP-BHG712 is an oral active EphB4 kinase autophosphorylation inhibitor, with IC50 values of 3.3 nM and 3.0 nM for EphA2 and EphB4, respectively[1][2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BHG712. CAS No. 940310-85-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13258A. | |
| NVP-BHG712 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| NVP-BHG712 isomer | NVP-BHG712 isomer, a regioisomer of NVP-BHG712, shows conserved non-bonded binding to EPHA2 and EPHB4[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2245892-85-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13258. | |
| NVP-BKM 120 | NVP-BKM 120. Group: Biochemicals. Alternative Names: BKM 120; Buparlisib; 5-(2,6-di-4-Morpholinyl-4-pyrimidinyl)-4-(trifluoromethyl)-2-pyridinamine. Grades: Highly Purified. CAS No. 944396-07-0. Pack Sizes: 5mg. Molecular Formula: C18H21F3N6O2, Molecular Weight: 410.39. US Biological Life Sciences. | Worldwide |
| NVP-BSK805 dihydrochloride | NVP-BSK805 dihydrochloride is an ATP-competitive JAK2 inhibitor, with IC50s of 0.48 nM, 31.63 nM, 18.68 nM, and 10.76 nM for JAK2 JH1 (JAK homology 1), JAK1 JH1, JAK3 JH1, and TYK2 JH1, respectively[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1942919-79-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-14722A. | |
| NVP-CGM097 | NVP-CGM097 is a potent and selective MDM2 inhibitor with IC 50 of 1.7±0.1 nM for hMDM2. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CGM097. CAS No. 1313363-54-0. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15954. | |
| NVP-CGM097 sulfate | NVP-CGM097 sulfate is a potent and selective MDM2 inhibitor with IC 50 of 1.7±0.1 nM for hMDM2. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CGM097 sulfate. CAS No. 1313367-56-4. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15954B. | |
| NVP-DFF332 | HIF-2α-IN-8 is a potent and orally active HIF2α inhibitor with IC 50 values of 9, 37, 246 nM for HIF2α SPA, HIF2α iScript, HIF2α HRE RGA, respectively. HIF-2α-IN-8 shows antitumor activity [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: HIF-2α-IN-8. CAS No. 2734922-78-0. Pack Sizes: 5 mg; 10 mg. Product ID: HY-148860. | |
| NVP-DFV890 | NVP-DFV890 (Comopound 102) is a NLRP3 antagonist. NVP-DFV890 can be used for osteoarthritis research[1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: NLRP3 antagonist 2. CAS No. 2271394-34-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-155876. | |
| NVP-DKY709 | NVP-DKY709 is an orally active and selective IKZF2 molecular glue degrader with the Dmax and DC50 of 53% and 4 nM, respectively. In addition, NVP-DKY709 can degrade IKZF4 (DC50: 13 nM) and SALL4 (DC50: 2 nM). NVP-DKY709 exerts anti-tumor activity by binding with CRBN to change conformation and recruit and degrade IKZF2[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2291360-73-9. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-144998. | |
| NVP DPP 728 dihydrochloride | NVP DPP 728 dihydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 207556-62-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| NVP-HSP990 | NVP-HSP990 is a potent, selective and orally active Hsp90 inhibitor, with IC50 values of 0.6, 0.8, and 8.5 nM for Hsp90?, Hsp90?, and Grp94, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: HSP-990. CAS No. 934343-74-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15190. | |
| NVP-TAE 226 | NVP-TAE 226 (TAE226) is a potent and ATP-competitive dual FAK and IGF-1R inhibitor with IC50s of 5.5 nM and 140 nM, respectively. NVP-TAE 226 (TAE226) also effectively inhibits Pyk2 and insulin receptor (InsR) with IC50s of 3.5 nM and 44 nM, respectively[1][2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TAE226. CAS No. 761437-28-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13203. | |
| NVP-TAE 684 | NVP-TAE 684 (TAE 684) is a highly potent and selective ALK inhibitor, which blocks the growth of ALCL-derived and ALK-dependent cell lines with IC50 values between 2 and 10 nM[1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TAE 684. CAS No. 761439-42-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-10192. | |
| NVP-TNKS656 | NVP-TNKS656 is a highly potent, selective, and orally active TNKS2 inhibitor with IC 50 of 6 nM, and is > 300 fold selectivity against PARP1 and PARP2. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TNKS656. CAS No. 1419949-20-4. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13990. | |
| NVR 3-778 | NVR 3-778 is the first capsid assembly modulator (CAM) that has demonstrated antiviral activity in hepatitis B virus (HBV)-infected patients. NVR 3-778 inhibited the generation of infectious HBV DNA-containing virus particles with a mean antiviral 50% effective concentration (EC50) of 0.40?μM in HepG2.2.15 cells. The antiviral profile of NVR 3-778 indicates pan-genotypic antiviral activity and a lack of cross-resistance with nucleos(t)ide inhibitors of HBV replication. Uses: Designed for use in research and industrial production. Additional or Alternative Names: NVR 3 778; NVR3 778; NVR-3-778; K-89; K 89; K89; NVR3778; NVR 3778; NVR-3778. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 1445790-55-5. Molecular formula: C18H16F4N2O4S. Mole weight: 432.39. Purity: >98%. IUPACName: 4-Fluoro-3-((4-hydroxypiperidin-1-yl)sulfonyl)-N-(3,4,5-trifluorophenyl)benzamide. Canonical SMILES: O=C(NC1=CC(F)=C(F)C(F)=C1)C2=CC=C(F)C(S(=O)(N3CCC(O)CC3)=O)=C2. Product ID: ACM1445790555. Alfa Chemistry ISO 9001:2015 Certified. |  |
| NVS-CECR2-1 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| NVS-CECR2-1 | NVS-CECR2-1, a non-BET family Bromodomain (BRD) inhibitor, is a potent and selective cat eye syndrome chromosome region, candidate 2 ( CECR2 ) inhibitor. NVS-CECR2-1 binds to CECR2 BRD with high affinity ( IC 50 =47 nM; K D =80 nM). NVS-CECR2-1 exhibits cytotoxic activity and induces apoptosis against various cancer cells by targeting CECR2 as well as via CECR2-independent mechanism [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1992047-61-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-110374. | |
| NVS-PAK1-1 | NVS-PAK1-1 is a specific allosteric PAK1 inhibitor. Uses: Designed for use in research and industrial production. Additional or Alternative Names: NVS-PAK1-1; NVSPAK11; NVS PAK1 1. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 1783816-74-9. Molecular formula: C23H25ClF3N5O. Mole weight: 479.93. Purity: >98%. IUPACName: 3(S)-[2-Chloro-5-(2,2-difluoro-ethyl)-8-fluoro-5H-dibenzo[b,e][1,4]diazepin-11-ylamino]-pyrrolidine-1-carboxylic acid isopropylamide. Canonical SMILES: O=C(N1C[C@@H](NC2=NC3=CC(F)=CC=C3N(CC(F)F)C4=CC=C(Cl)C=C42)CC1)NC(C)C. Product ID: ACM1783816749. Alfa Chemistry ISO 9001:2015 Certified. | |
| NVS-PAK1-1 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| NVS-PAK1-1 | NVS-PAK1-1 is a potent and selective allosteric PAK1 inhibitor with an IC 50 of 5 nM. Uses: Scientific research. Group: Signaling pathways. CAS No. 1783816-74-9. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100519. | |
| NVS-PAK1-C | NVS-PAK1-C is a potent, ATP-competitive and specific allosteric PAK1 inhibitor probe with IC 50 values of 5 nM and 6 nM for dephosphorylated PAK1 and phosphorylated PAK1, respectively. NVS-PAK1-C is also against dephosphorylated PAK2 ( IC 50 =270 nM) and phosphorylated PAK2 ( IC 50 =720 nM) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2250019-95-3. Pack Sizes: 1 mg; 5 mg. Product ID: HY-131043. | |
| Nw- (2, 2, 4, 6, 7-Penta methyl dihydrobenzofuran) -5-sulfonyl-D-arginine | Nw- (2, 2, 4, 6, 7-Penta methyl dihydrobenzofuran) -5-sulfonyl-D-arginine. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 250mg, 1g, 5g. US Biological Life Sciences. | Worldwide |
| Nw- (2, 2, 4, 6, 7-Penta methyl dihydrobenzofuran-5-sulfonyl) -L-arginine 99+% (HPLC) | Nw- (2, 2, 4, 6, 7-Penta methyl dihydrobenzofuran-5-sulfonyl) -L-arginine 99+% (HPLC). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 5g, 25g. US Biological Life Sciences. | Worldwide |
| Nw- (2, 2, 4, 6, 7-Penta methyl dihydrobenzofuran-5-sulfonyl) -L-arginine allyl ester hydrochloride ≥95% (HPLC) | Nw- (2, 2, 4, 6, 7-Penta methyl dihydrobenzofuran-5-sulfonyl) -L-arginine allyl ester hydrochloride ≥95% (HPLC). Group: Biochemicals. Grades: Reagent Grade. CAS No. 257288-23-6. Pack Sizes: 1g, 5g, 25g. US Biological Life Sciences. | Worldwide |
| Nw- (2, 2, 4, 6, 7-Penta methyl dihydrobenzofuran-5-sulfonyl) -L-arginine methyl ester hydrochloride 99+% (TLC) | Nw- (2, 2, 4, 6, 7-Penta methyl dihydrobenzofuran-5-sulfonyl) -L-arginine methyl ester hydrochloride 99+% (TLC). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 5g, 25g. US Biological Life Sciences. | Worldwide |
| Nw-(2,2,5,7,8-Pentamethylchroman-6-sulfonyl)-D-arginine | Nw-(2,2,5,7,8-Pentamethylchroman-6-sulfonyl)-D-arginine. Group: Biochemicals. Alternative Names: D-Arg(Pmc)-OH. Grades: Highly Purified. CAS No. 191869-60-0. Pack Sizes: 500mg, 1g, 2g, 5g. US Biological Life Sciences. | Worldwide |
| Nw-(2,2,5,7,8-Pentamethylchroman-6-sulfonyl)-D-arginine-2-chlorotrityl resin | Nw-(2,2,5,7,8-Pentamethylchroman-6-sulfonyl)-D-arginine-2-chlorotrityl resin. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 5g. US Biological Life Sciences. | Worldwide |
| Nw-(2,2,5,7,8-Pentamethylchroman-6-sulfonyl)-D-arginine 98+% (TLC) | Nw-(2,2,5,7,8-Pentamethylchroman-6-sulfonyl)-D-arginine 98+% (TLC). Group: Biochemicals. Grades: Reagent Grade. CAS No. 191869-60-0. Pack Sizes: 1g, 5g. US Biological Life Sciences. | Worldwide |
| Nw-(2,2,5,7,8-Pentamethylchroman-6-sulfonyl)-L-arginine | Nw-(2,2,5,7,8-Pentamethylchroman-6-sulfonyl)-L-arginine. Group: Biochemicals. Alternative Names: L-Arg(Pmc)-OH. Grades: Highly Purified. CAS No. 112160-37-9. Pack Sizes: 1g, 2g, 5g, 10g, 25g. US Biological Life Sciences. | Worldwide |
| Nw-(2,2,5,7,8-Pentamethylchroman-6-sulfonyl)-L-arginine 99+% (TLC) | Nw-(2,2,5,7,8-Pentamethylchroman-6-sulfonyl)-L-arginine 99+% (TLC). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 5g, 25g. US Biological Life Sciences. | Worldwide |
| Nw- (4-Methoxy-2, 3, 6-trimethyl Benzene sulfonyl) -L-arginine 98+% (HPLC) | Nw- (4-Methoxy-2, 3, 6-trimethyl Benzene sulfonyl) -L-arginine 98+% (HPLC). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 5g, 25g, 100g. US Biological Life Sciences. | Worldwide |
| Nw- (4-Methoxy-2, 3, 6-trimethyl Benzene sulfonyl) -L-arginine tert-butyl ester 99+% (TLC) | Nw- (4-Methoxy-2, 3, 6-trimethyl Benzene sulfonyl) -L-arginine tert-butyl ester 99+% (TLC). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 250mg, 1g. US Biological Life Sciences. | Worldwide |
| Nw-(4-Toluenesulfonyl)-D-arginine ≥97% (HPLC) | Nw-(4-Toluenesulfonyl)-D-arginine ≥97% (HPLC). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 5g, 25g. US Biological Life Sciences. | Worldwide |
| Nw-(4-Toluenesulfonyl)-L-arginine 98+% (HPLC) | Nw-(4-Toluenesulfonyl)-L-arginine 98+% (HPLC). Group: Biochemicals. Grades: Reagent Grade. CAS No. 4353-32-6. Pack Sizes: 1g, 5g, 10g, 25g, 100g. US Biological Life Sciences. | Worldwide |
| N-w-Hydroxy-L-norarginine | N-w-Hydroxy-L-norarginine. Group: Biochemicals. Alternative Names: nor-NOHA; L-2-Amino-{4- (2'-hydroxyguanidino) butyric acid. Grades: Highly Purified. CAS No. 189302-40-7. Pack Sizes: 10mg, 25mg, 50mg, 100mg, 250mg. US Biological Life Sciences. | Worldwide |
| N-w-Hydroxy-L-norarginine diacetate salt | N-w-Hydroxy-L-norarginine diacetate salt. Synonyms: nor-NOHA diacetate; L-2-Amino-{4-(2'-hydroxyguanidino)butyric acid diacetate. Grade: ≥ 97% (TLC). CAS No. 189302-40-7. Molecular formula: C5H12N4O3·2C2H4O2. Mole weight: 296.278. |  |
| N-w-Hydroxy-L-norarginine diacetate salt ≥97% (TLC) | N-w-Hydroxy-L-norarginine diacetate salt ≥97% (TLC). Group: Biochemicals. Grades: Reagent Grade. CAS No. 189302-40-7. Pack Sizes: 250mg, 25mg, 50mg, 1g. US Biological Life Sciences. | Worldwide |
| Nw-Methyl-L-arginine hydrochloride ≥95% (HPLC) | Nw-Methyl-L-arginine hydrochloride ≥95% (HPLC). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 50mg, 100mg, 250mg. US Biological Life Sciences. | Worldwide |
| Nw-Nitro-D-arginine 98+% (HPLC) | Nw-Nitro-D-arginine 98+% (HPLC). Group: Biochemicals. Grades: Reagent Grade. CAS No. 66036-77-9. Pack Sizes: 5g, 25g, 100g, 250g. US Biological Life Sciences. | Worldwide |
| Nw-Nitro-D-arginine methyl ester hydrochloride 99+% (HPLC) | Nw-Nitro-D-arginine methyl ester hydrochloride 99+% (HPLC). Group: Biochemicals. Grades: Reagent Grade. CAS No. 50912-92-0. Pack Sizes: 1g, 5g, 25g. US Biological Life Sciences. | Worldwide |
| Nw-Nitro-L-arginine 99+% | Nw-Nitro-L-arginine 99+%. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 25g, 100g, 250g, 1Kg. US Biological Life Sciences. | Worldwide |
| Nw-Nitro-L-arginine methyl ester hydrochloride | Nw-Nitro-L-arginine methyl ester hydrochloride. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 5g, 25g, 100g, 250g. US Biological Life Sciences. | Worldwide |
| Nw,Nw'-Di-Z-L-arginine | Nw,Nw'-Di-Z-L-arginine. Group: Biochemicals. Grades: Reagent Grade. CAS No. 4125-79-5. Pack Sizes: 250mg, 1g, 5g, 25g. US Biological Life Sciences. | Worldwide |
| Nw-Propyl-L-Arginine | A highly selective competitive inhibitor and inactivator of all three isoforms of NOS. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| NX-1607 | NX-1607 (Compound 23) is an inhibitor of Cbl-b , an E3 enzyme in the ubiquitin-proteasome pathway, with an IC 50 value of less than 1 nM. NX-1607 can be used in cancer research [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Cbl-b-IN-3. CAS No. 2573775-59-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-141432. | |
| NX-2127 | NX-2127 (compound 28) is an orally active PROTAC deggrader, targeting to Brutons Tyrosine Kinase (Btk). NX-2127 inhibits proliferation of BTK C481S mutant TMD8 cells, more effectively than Ibrutinib (HY-10997). NX-2127 catalyzes the degradation of Ikaros (IKZF1) and Aiolos (IKZF3) with of 25 nM and 54 nM, respectively. NX-2127 stimulates T cell activation and increases IL-2 production in primary human T Cells [1] [2]. NX-2127 is composed of PROTAC target protein ligand (red part) BTK ligand 10 (HY-168302), E3 ligase ligand (blue part) Thalidomide 5-fluoride (HY-W087383) and PROTAC Linker (black part) (S)-4-(1-(Pyrrolidin-3-ylmethyl)piperidin-4-yl)aniline (HY-168303). Among which, the conjugate of E3 ubiquitin ligase ligand + Linker compose of Thalidomide-pyrrolidine-C-piperidine-Ph-NH2 (HY-168304). Uses: Scientific research. Group: Signaling pathways. CAS No. 2416131-46-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-153220. | |
| NX-5948 | NX-5948 (BTK-IN-24) is an orally active chimeric targeting molecule (CTM) that induces specific BTK protein degradation by the cereblon E3 ligase (CRBN) complex without degradation of other cereblon neo-substrates. NX-5948 mediates potent anti-inflammatory activity via BTK degradation with resultant inhibition of B cell activation. NX-5948 exhibits potent tumor growth inhibition in TMD8 xenograft models that contain either wild-type BTK or BTKi-resistant mutations. NX-5948 is efficacious in a mouse collageninduced arthritis (CIA) model. NX-5948 can cross the blood brain barrier (BBB). NX-5948 is a PROTAC composed of the ligand for target protein, a linker, and a cereblon E3 ligase (CRBN) complex (Red: ligand for target protein; Blue: CRBN; Black: linker) [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BTK-IN-24. CAS No. 2649400-34-8. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-153321. | |
| NXE0041178 | NXE0041178 (Procedure 1) is a GPR52 receptor modulator with the potential to study neuropsychiatric diseases[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2642079-89-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-154980. | |
| NXP800 | NXP800 (CCT361814) is a potent and orally active heat shock factor 1 (HSF1) pathway inhibitor. NXP800 has the potential for cancer research [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CCT361814. CAS No. 1693734-80-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145927. | |
| NXT629 | NXT629 is a potent, selective, and competitive PPAR-? antagonist, with an IC50 of 77 nM for human PPAR?, shows high selectivity over other nuclear hormone receptor, such as PPAR?, PPAR?, ER?, GR and TR?, IC50s are 6.0, 15, 15.2, 32.5 and >100 ?M, respectively[1]. NXT629 has potent anti-tumor activity and inhibits experimental metastasis of cancer cell in animal models[2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1454925-59-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-114263. | |
| NXY 059 | NXY 059. Group: Biochemicals. Grades: Purified. CAS No. 168021-79-2. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| NYAD-1 | NYAD-1 is a cell-penetrating alpha-helical peptide that is used as a potential HIV-1 inhibitor. The hydrocarbon-stapled structure enhances alpha helicity. Synonyms: H-Ile-Thr-Phe-X-Asp-Leu-Leu-X-Tyr-Tyr-Gly-Pro-NH2. Grade: ≥95%. Mole weight: 1450.70. | |
| Nyasol | Nyasol is purified from the rhizomes of Anemarrhena asphodeloides. Nyasol may have the potential to be developed as a medicine for the treatment of allergies by inhibiting the activation of mast cells. Nyasol has antifungal activity and suppresses the Phytophthora blight on pepper plants. Synonyms: Cis-Hinokiresinol. Grade: 98.0%. CAS No. 96895-25-9. Molecular formula: C17H16O2. Mole weight: 252.31. | |
| Nybomycin | An unusual heterocyclic metabolite isolated from several streptomyces species; possesses antiviral and antibacterial activity. Synonyms: NSC613948; 8-(Hydroxymethyl)-6,11-dimethyl-2H,4H-oxazolo[5,4,3-ij]pyrido[3,2-g]quinoline-4,10(11H)-dione; 8,9-Dihydro-4-(hydroxymethyl)-6,9-dimethyl-2,8-dioxopyrido(3,2-g)quinoline-1(2H)-carboxaldehyde. Grade: >95% by HPLC. CAS No. 30408-30-1. Molecular formula: C16H14N2O4. Mole weight: 298.29. | |
| Nybomycin | Nybomycin, an antibiotic, exhibits antiphage and antibacterial properties. Nybomycin binds to DNA and induces a unique morphological change to mycobacterial bacilli leading the bacterial cell death [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 30408-30-1. Pack Sizes: 500 μg. Product ID: HY-123635. | |
| NY-BR-1 p904 A2 | It is an HLA-A2-restricted NY-BR-1 epitope. T-cell clone specific for NY-BR-1 p904 can recognize breast tumor cells expressing NY-BR-1. Synonyms: L-Valine, L-seryl-L-leucyl-L-seryl-L-lysyl-L-isoleucyl-L-leucyl-L-α-aspartyl-L-threonyl-; H-Ser-Leu-Ser-Lys-Ile-Leu-Asp-Thr-Val-OH. Grade: ≥95%. CAS No. 347142-73-8. Molecular formula: C43H78N10O15. Mole weight: 975.14. | |
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