A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
White crystalline. CAS No. 627-06-5. Pack Sizes: 25g, 100g. Product ID: FR-1259. M.P. 106-108. Mole weight: 102.14.
Frinton Laboratories
NPS-1034
NPS-1034 is a novel MET inhibitor, which inhibits the activated MET receptor and its constitutively active mutants. NPS-1034, inhibits various constitutively active mutant forms of MET as well as HGF-activated wild-type MET. NPS-1034 inhibited the proliferation of cells expressing activated MET and promoted the regression of tumors formed from such cells in a mouse xenograft model through anti-angiogenic and pro-apoptotic actions. NPS-1034 also inhibited HGF-stimulated activation of MET signaling in the presence or absence of serum. Notably, NPS-1034 inhibited three MET variants that are resistant to the MET inhibitors SU11274, NVP-BVU972, and PHA665752. Synonyms: NPS-1034; NPS1034; NPS 1034. Grades: 98%. CAS No. 1221713-92-3. Molecular formula: C31H23F2N5O3. Mole weight: 551.554.
NPS-2143
NPS-2143(SB 262470A ) is a selective potent calcium ion-sensing receptor antagonist with IC50 of 43 and 41 nM for cytoplasmic Ca2+ concentrations and parathyroid hormone secretion, respectively. Synonyms: SB-262470; NPS-2143; SB 262470; NPS 2143; SB262470; NPS2143. Grades: >98%. CAS No. 284035-33-2. Molecular formula: C24H25ClN2O2. Mole weight: 408.92.
NPS-2143
NPS-2143 (SB-262470A), an orally active calcilytic agent, is a selective and potent calcium ion-sensing receptor (CaSR) antagonist. NPS-2143 (SB-262470A) blocks increases in cytoplasmic Ca 2+ concentrations ( IC 50 =43 nM) elicited by activating the Ca 2+ receptor in HEK 293 cells expressing the human Ca 2+ receptor [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SB-262470A. CAS No. 284035-33-2. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-10007.
NPS 2143 hydrochloride
NPS 2143 hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 324523-20-8. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
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NPS-2143 hydrochloride
NPS-2143 (SB-262,470A) is a calcilytic drug which acts as an antagonist at the Calcium-sensing receptor (CaSR), and consequently stimulates release of parathyroid hormone. Calcilytic drugs have been researched as potential treatments for osteoporosis, and as the first such compound developed, NPS-2143 is still widely used in research into the CaSR receptor as well as design of newer calcilytic agents. Synonyms: NPS2143 hydrochloride; NPS 2143 hydrochloride. Grades: >98%. CAS No. 324523-20-8. Molecular formula: C24H26Cl2N2O2. Mole weight: 445.38.
NPS-2143 hydrochloride
NPS-2143 hydrochloride (SB-262470A hydrochloride), an orally active calcilytic agent, is a selective and potent calcium ion-sensing receptor (CaSR) antagonist. NPS-2143 hydrochloride (SB-262470A hydrochloride) blocks increases in cytoplasmic Ca 2+ concentrations ( IC 50 =43 nM) elicited by activating the Ca 2+ receptor in HEK 293 cells expressing the human Ca 2+ receptor [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SB-262470A hydrochloride. CAS No. 324523-20-8. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg. Product ID: HY-10171.
NPS 2390 is a Group I mGlu antagonist. NPS 2390 acts as a noncompetitive antagonist of mGluR1 and mGluR5 with IC50 values of 5.2 and 82 nM. Synonyms: N-tricyclo[3.3.1.13,7]dec-1-yl-2-quinoxalinecarboxamide. Grades: ≥99% by HPLC. CAS No. 226878-01-9. Molecular formula: C19H21N3O. Mole weight: 307.39.
NPS 2390
NPS 2390 is a noncompetitive antagonist of mGluR1 and mGluR5 [1]. NPS 2390 is also a potent CaSR (calcium-sensing receptor) inhibitor [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 226878-01-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-11095.
NPS 2390
NPS 2390. Group: Biochemicals. Grades: Purified. CAS No. 226878-01-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
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NPS ALX Compound 4a dihydrochloride
NPS ALX Compound 4a dihydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 299433-10-6. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
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NPS ALX Compound 4a dihydrochloride
NPS ALX Compound 4a dihydrochloride is a 5-HT6 antagonist with IC50 value of 7.2 nM. Synonyms: 6-(Hexahydropyrrolo[1,2-a]pyrazin-2(1H)-yl)-1-(1-naphthalenylsulfonyl)-1H-indole dihydrochloride. Grades: ≥99% by HPLC. CAS No. 299433-10-6. Molecular formula: C25H25N3O2S.2HCl. Mole weight: 504.47.
N-(p-Sulfamoylphenethyl)acetamide
N-(p-Sulfamoylphenethyl)acetamide. Uses: Designed for use in research and industrial production. Additional or Alternative Names: N-ACETYL-4-(2-AMINOETHYL)-BENZENESULFONAMIDE;N-ACETYL (2-AMINOETHYL)BENZENE SULPHONAMIDE;N-(P-SULFAMOYLPHENETHYL)ACETAMIDE;4-(2-acetylaminoethyl)benzenesulfonamide;N-[2-[4-(aminosulphonyl)phenyl]ethyl]acetamide;4-[2-(N-Acetylamino)-ethyl]-benzenesulfonam. Product Category: Heterocyclic Organic Compound. CAS No. 41472-49-5. Molecular formula: C10H14N2O3S. Mole weight: 242.29. Density: 1.274 g/cm³. Product ID: ACM41472495. Alfa Chemistry ISO 9001:2015 Certified.
NpThio1
NpThio1 is an antimicrobial peptide found in Nicotiana paniculata, and has antifungal activity. Synonyms: NpThio1 (Plant defensin). Molecular formula: C229H376N66O65S8. Mole weight: 5350.44.
N-p-Tosyl-Gly-Pro-Lys p-nitroanilide acetate salt is a chromogenic substrate for plasmin determination, serine protease activity and fibrinogen decomposition determination. Synonyms: N-(p-Tosyl)-Gly-Pro-Lys 4-nitroanilide acetate salt; Tos-GPK-pNA; Tos-Gly-Pro-Lys-pNA acetate; N-[(4-methylphenyl)sulfonyl]glycyl-L-prolyl-N-(4-nitrophenyl)-L-lysinamide, monoacetate. Grades: ≥98% by TLC. CAS No. 88793-79-7. Molecular formula: C28H38N6O9S. Mole weight: 634.7.
N-p-Tosyl-L-phenylalanine
N-p-Tosyl-L-phenylalanine. Uses: Designed for use in research and industrial production. Additional or Alternative Names: NCIOpen2_009805, Oprea1_534866, MLS000776584, ZERO/006235, ALBB-006226, CID309599, NSC211907, SMR000371829, EU-0000301, 2-{[(4-methylphenyl)sulfonyl]amino}-3-phenylpropanoic acid, 13505-32-3. Product Category: Heterocyclic Organic Compound. CAS No. 13505-32-3. Molecular formula: C16H17NO4S. Mole weight: 319.37. Purity: 0.96. IUPACName: 2-[(4-methylphenyl)sulfonylamino]-3-phenylpropanoic acid. Canonical SMILES: CC1=CC=C(C=C1)S(=O)(=O)NC(CC2=CC=CC=C2)C(=O)O. Density: 1.303g/cm³. Product ID: ACM13505323. Alfa Chemistry ISO 9001:2015 Certified.
NPY 5RA972
NPY 5RA972. Group: Biochemicals. Grades: Purified. CAS No. 439861-56-0. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
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NPY 5RA972
NPY5RA972 is a neuropeptide Y Y5 antagonist. Synonyms: NPY5RA972; NPY-5-RA-972; NPY 5 RA 972; N-[4-Methyl-9-(1-methylethyl)-9H-carbazol-3-yl]-4-morpholinecarboxamide. Grades: ≥98% by HPLC. CAS No. 439861-56-0. Molecular formula: C21H25N3O2. Mole weight: 351.44.
N-Pyrazinylcarbonyl-L-phenylalanine
N-Pyrazinylcarbonyl-L-phenylalanine. Group: Biochemicals. Alternative Names: N-(2-pyrazinylcarbonyl)-L-phenylalanine. Grades: Highly Purified. CAS No. 114457-94-2. Pack Sizes: 100mg, 250mg, 500mg, 1g, 2g. Molecular Formula: C14H13N3O3. US Biological Life Sciences.
Worldwide
N-Pyrazinylcarbonyl-L-phenylalanine methyl ester
Used for the synthesis of Bortezomib from L-phenylalanine via dipeptidyl boronic acid ester intermediates. Group: Biochemicals. Alternative Names: N-(2-Pyrazinylcarbonyl)-L-phenylalanine Methyl Ester; 3-Phenyl-2-[ (pyrazine-2-carbonyl) amino]propionic Acid Methyl Ester. Grades: Highly Purified. CAS No. 73058-37-4. Pack Sizes: 100mg, 250mg, 500mg, 1g. Molecular Formula: C??H??N?O?, Molecular Weight: 285.3. US Biological Life Sciences.
Worldwide
N-Pyrazinylcarbonyl-L-phenylalanine Methyl Ester
N-Pyrazinylcarbonyl-L-phenylalanine Methyl Ester. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Bortezomib Impurity R. Appearance: White Powder. CAS No. 73058-37-4. Molecular formula: C15H15N3O3. Mole weight: 285.29. Purity: 0.95. Product ID: ACM73058374. Alfa Chemistry ISO 9001:2015 Certified. Categories: DTXSID90503277.
N-Pyrazinyl carbonyl phenyl alanine Methyl Ester (3-Phenyl-2-[(pyrazine-2-carbonyl)-amino]-propionic Acid Methyl Ester). Group: Biochemicals. Alternative Names: 3-Phenyl-2-[(pyrazine-2-carbonyl)-amino]-propionic Acid Methyl Ester. Grades: Highly Purified. Pack Sizes: 250mg. US Biological Life Sciences.
Worldwide
N-Pyridin-2-yl-Oxalamic Acid Ethyl Ester
Synonyms: EdoxaBan impurity K. Grades: > 95%. CAS No. 41374-72-5. Molecular formula: C9H10N2O3. Mole weight: 194.19.
N-(Pyridin-3-ylmethyl)ethanamine
N-(Pyridin-3-ylmethyl)ethanamine (CAS# 3000-75-7) is used as a reagent in organic synthesis, in particular, that of bis-nicotine derivatives which act as inhibitors of cholinesterases and β-amyloid aggregation. It is also used in the synthesis of [11C]EMPA which acts as a potential PET tracer for orexin 2 receptors. N-(Pyridin-3-ylmethyl)ethanamine is also a nicotinic analog. Synonyms: N-(Pyridin-3-ylmethyl)ethylamine; N-Ethyl-3-pyridinemethanamine; N-Ethyl-N-(3-pyridylmethyl)amine; N-Ethyl-N-(pyridin-3-ylmethyl)amine; N-Ethyl[(3-pyridyl)methyl]amine; N-Ethyl[(pyridin-3-yl)methyl]amine; 3-[(Ethylamino)methyl]pyridine; α-Ethylamino-3-Picoline. Grades: ≥95%. CAS No. 3000-75-7. Molecular formula: C8H12N2. Mole weight: 136.19.
N-Pyridin-4-yl-4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-benzamide. Uses: Designed for use in research and industrial production. Additional or Alternative Names: N-PYRIDIN-4-YL-4-(4,4,5,5-TETRAMETHYL-[1,3,2]DIOXABOROLAN-2-YL)-BENZAMIDE. Product Category: Heterocyclic Organic Compound. CAS No. 864759-38-6. Molecular formula: C18H21BN2O3. Mole weight: 324.18194. Product ID: ACM864759386. Alfa Chemistry ISO 9001:2015 Certified.
N- (Pyridin-4-Ylmethyl) Methanesulfonamide
N- (Pyridin-4-Ylmethyl) Methanesulfonamide. Group: Biochemicals. Grades: Reagent Grade. CAS No. 349404-63-3. Pack Sizes: 100mg, 250mg, 1g. US Biological Life Sciences.
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N-Pyrrolo-2'-deoxycytidine
N-Pyrrolo-2'-deoxycytidine. Group: Biochemicals. Alternative Names: 6-Methyl-3- (b-D-2-deoxyribofuranosyl) pyrrolo[2, 3-d]pyrimidin-2-one. Grades: Highly Purified. CAS No. 382137-74-8. Pack Sizes: 10mg, 50mg, 100mg. Molecular Formula: C12H15N3O4. US Biological Life Sciences.
NQ301 is an antithrombotic agent; inhibits collagen-challenged rabbit platelet aggregation with an IC 50 of 10 mg/mL. Uses: Scientific research. Group: Signaling pathways. CAS No. 130089-98-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101054.
NQ 301
NQ 301 is a CD45 inhibitor with IC50 value of 200 nM. It can block inflammation in a delayed-type hypersensitivity model in vivo. Synonyms: NQ-301; NQ 301; NQ301. 2-[(4-Acetylphenyl)amino]-3-chloro-1,4-naphthalenedione. Grades: ≥98% by HPLC. CAS No. 130089-98-4. Molecular formula: C18H12ClNO3. Mole weight: 325.75.
NQDI 1
NQDI 1. Group: Biochemicals. Grades: Purified. CAS No. 175026-96-7. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
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NQDI-1
NQDI-1 is an inhibitor of ASK1, which attenuates acute ischemic renal injury by modulating oxidative stress and cell death. Synonyms: NQDI1; NQDI-1; NQDI 1. CAS#175026-96-7. Grades: 98%. CAS No. 175026-96-7. Molecular formula: C19H13NO4. Mole weight: 319.31.
NQO1 substrate acts as an efficient NQO1 substrate and may be a new option for the treatment of NQO1-overexpresssing drug-resistant NSCLC [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2304503-05-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-114315.
N-(Quinoxalin-2-yl)-4-(quinoxalin-2-ylamino)benzenesulfonamide, an intriguing chemical substance, has garnered interest in the biomedical domain as a plausible remedy for assorted cancer types. This compound exerts its therapeutic effects by curbing certain enzymes and provoking apoptosis in malignant cells, thereby causing their demise. Although promising, further scientific investigations and clinical deliberations are fundamental to ascertain its potency and risk profiles. Grades: 98.0%. Molecular formula: C22H16N6O2S. Mole weight: 428.474.
N-[(R)-1-Phenylethyl]acetamide
N-[(R)-1-Phenylethyl]acetamide. Group: Biochemicals. Alternative Names: (+)-N-(1-Phenylethyl)acetamide; (R)-1-Acetamido-1-phenylethane; (R)-N-Acetyl-1-phenylethylamine; (α R) -N- (α -Methylphenyl) acetamide. Grades: Highly Purified. CAS No. 36283-44-0. Pack Sizes: 1g. US Biological Life Sciences.
Worldwide
N-[(R)-(+)-1-Phenylethyl]imidazole-1-carboxamide
N-[(R)-(+)-1-Phenylethyl]imidazole-1-carboxamide. Uses: Designed for use in research and industrial production. Additional or Alternative Names: (R)-N-(1-Phenylethyl)-1H-imidazole-1-carboxamide. Product Category: Heterocyclic Organic Compound. CAS No. 1217846-28-0. Molecular formula: C12H13N3O. Mole weight: 215.25. Purity: 0.96. IUPACName: N-[(1R)-1-phenylethyl]imidazole-1-carboxamide. Canonical SMILES: CC(C1=CC=CC=C1)NC(=O)N2C=CN=C2. Product ID: ACM1217846280. Alfa Chemistry ISO 9001:2015 Certified.
N-[(R)-(+)-1-Phenylethyl]imidazole-1-carboxamide
N-[(R)-(+)-1-Phenylethyl]imidazole-1-carboxamide. Group: Biochemicals. Alternative Names: (R)-N-(1-Phenylethyl)-1H-imidazole-1-carboxamide. Grades: Highly Purified. CAS No. 1217846-28-0. Pack Sizes: 500mg, 1g, 2g, 5g, 10g. Molecular Formula: C12H13N3O. US Biological Life Sciences.
Worldwide
NRC-11
NRC-11 is an antimicrobial peptide found in Hippoglossoides platessoides (American plaice AP1), and has antibacterial and antifungal activity. Synonyms: Gly-Trp-Lys-Ser-Val-Phe-Arg-Lys-Ala-Lys-Lys-Val-Gly-Lys-Thr-Val-Gly-Gly-Leu-Ala-Leu-Asp-His-Tyr-Leu-NH2. Grades: ≥96%. Molecular formula: C129H209N37O30. Mole weight: 2758.32.
NRC-12
NRC-12 is an antimicrobial peptide found in Hippoglossoides platessoides (American plaice AP2), and has antibacterial and antifungal activity. Synonyms: Gly-Trp-Lys-Lys-Trp-Phe-Asn-Arg-Ala-Lys-Lys-Val-Gly-Lys-Thr-Val-Gly-Gly-Leu-Ala-Val-Asp-His-Tyr-Leu-NH2. Grades: ≥97%. Molecular formula: C135H209N39O30. Mole weight: 2858.40.
NRC-17 is an antimicrobial peptide found in Glyptocephalus cynoglossus L. (Witch flounder GC3.8), and has antibacterial and antifungal activity. Synonyms: H-Gly-Trp-Lys-Lys-Trp-Leu-Arg-Lys-Gly-Ala-Lys-His-Leu-Gly-Gln-Ala-Ala-Ile-Lys-Gly-Leu-Ala-Ser-OH. Grades: ≥98%. Molecular formula: C116H190N36O26. Mole weight: 2505.02.
NRC-2694
NRC-2694 is a small molecule antagonist of epidermal growth factor receptor (EGFR) signalling pathways, for the treatment of solid tumors. Synonyms: NRC-2694; NRC 2694; NRC2694; N-(3-ethynylphenyl)-7-methoxy-6-(3-morpholinopropoxy)quinazolin-4-amine; NRC-2694; NRC 2694; NRC2694; 4-Quinazolinamine, N-(3-ethynylphenyl)-7-methoxy-6-(3-(4-morpholinyl)propoxy)-. CAS No. 936446-61-6. Molecular formula: C24H26N4O3. Mole weight: 418.49.
NR-CL
Nicotinamide riboside is a precursor of nicotinamide adenine dinucleotide (NAD) and represents a source of vitamin B3. Synonyms: Nicotinamideribosidechloride; NicotinamideB-DRibosideChloride(WX900111); NicotinamideRiboside.Cl; Nicotimideribosidechloride; Pyridinium, 3-(aminocarbonyl)-1-β -D-ribofuranosyl-, chloride(1:1); 3-carbamoyChemicalbookl-1-((2R, 3R, 4S, 5R)-3, 4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyridin-1-iumchloride; 3-Carbamoyl-1-(β -D-ribofuranosyl)pyridiniumchloride; 3-Carbamoyl-1-beta-D-ribofuranosylpyridiniumchloride. CAS No. 23111-00-4. Product ID: PAP-0088. Molecular formula: C11H15ClN2O5. Product Keywords: Other Active Pharmaceutical Ingredients; NR-CL; PAP-0088; ; C11H15ClN2O5; 23111-00-4. Appearance: White Powder. Chemical Name: Pyridinium,3-(aminocarbonyl)-1-β-D-ribofuranosyl-,chloride(1:1). Grade: Pharmaceutical Grade. Color: White. Solubility: Soluble to 100 mM in DMSO and to 100 mM in water. Storage: under inert gas (nitrogen or Argon) at 2-8°C. Product Description: Nicotinamide riboside is a precursor of nicotinamide adenine dinucleotide (NAD) and represents a source of vitamin B3.
Nrf2 activator-1
Nrf2 activator-1 is a potent activator of NF-E2 related factor 2 ( Nrf2 ). Nrf2 activator-1 has the potential for the research of COPD and other respiratory diseases, including asthma, Acute Lung Injury (ALI), Acute Respiratory Distress Syndrome (ARDS) and pulmonary fibrosis (extracted from patent WO2018109647A1) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2230697-41-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145390.
Nrf2 activator-12
Nrf2 activator-12 (compund 10v) potently activates Nrf2 (EC50=83.5 nM) and exhibits promising pharmacological properties, reversing disease progression and alleviating demyelination in an experimental autoimmune encephalomyelitis mouse model [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 3020661-05-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-169201.
Nrf2-Activator-12G
Nrf2-Activator-12G (compd 12g) is an activator of Nrf2. Nrf2-Activator-12G induces the expression of nrf2-dependentantioxidant enzymes at both mRNA and protein levels in DAergic neuronal cell. Nrf2-Activator-12G can used in study Parkinsons Disease [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1554271-18-9. Pack Sizes: 5 mg; 10 mg. Product ID: HY-115849.
Nrf2 Activator II, AI-1 (Ethyl-4-chloro-1-methyl-2-oxo-1,2-dihydroquinoline-3-carboxylate)
A cell-permeable chloro-quinolinone compound that selectively and covalently modifies Kelch-like ECH-associated protein 1 (Keap1)-Cys151 and represses Keap1 function and reduces Nrf2 (Nuclear factor E2-related factor 2)-Keap1 interaction. Shown to stabilize Nrf2 by inhibiting the Keap1-driven ubiquitination of Nrf2 and thereby activating the Nrf2-ARE (antioxidant response element) pathway (EC50 = 2.7uM in neuroblastoma IMR-32 cells). Offers protection against H2O2 induced oxidative stress, but unlike tert-butylhydroquinone AI-1 does not act as a free radical scavenger. Its anti-oxidant effects are mediated via Nrf2 induced antioxidant response. Does not affect mutant ARE where GC are substituted with AT within the core ARE sequence. Group: Biochemicals. Grades: Highly Purified. CAS No. 75483-04-4. Pack Sizes: 25mg. US Biological Life Sciences.