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(-)-U-50488 hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 114528-79-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
(-)-U-50488 hydrochloride
(-)-U-50488 hydrochloride is the more active enantiomer of (±)-U-50488, which is an opioid receptor agonist. Synonyms: (-)-U-50488 hydrochloride; (-)-U 50488 hydrochloride; (-)-U50488 hydrochloride; trans- (-) -3, 4-Dichloro-N-methyl-N-[2- (1-pyrrolidinyl) cyclohexyl]benzeneacetamide hydrochloride; (-)-trans-(1S,2S)-U-50488 hydrochloride. Grades: ≥99% by HPLC. CAS No. 114528-79-9. Molecular formula: C19H26Cl2N2O.HCl. Mole weight: 405.79.
(-)-U-50488 hydrochloride
(-)-U-50488 hydrochloride ((-)-Trans-(1S,2S)-U-50488 hydrochloride) is a selective kappa-opioid receptor (KOR) agonist (b>K d=2.2 nM) over μ-opioid receptor (MOR) (b>K d =430 nM). (-)-U-50488 hydrochloride is a more active enantiomer than (+) trans-(1R,2R) U-50488 (HY-15997A) or the (±) trans-racemic mixture U-50488 (HY-15997B). (-)-U-50488 hydrochloride has a potent and sustained anti- HIV effect in fected blood monocyte-derived macrophages (MDM) [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (-)-Trans-(1S,2S)-U-50488 hydrochloride. CAS No. 114528-79-9. Pack Sizes: 5 mg; 10 mg. Product ID: HY-15997.
(+)-U-50488 hydrochloride
(+)-U-50488 hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 114528-81-3. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
(+)-U-50488 hydrochloride
(+)-U-50488 hydrochloride is the less active enantiomer of (±)-U-50488, which is an opioid receptor agonist. Synonyms: (±)-U-50488 hydrochloride; (±)-U 50488 hydrochloride; (±)-U50488 hydrochloride; trans-(+)-3,4-Dichloro-N-methyl-N-[2-(1-pyrrolidinyl)-cyclohexyl]benzeneacetamide hydrochloride; (+)-trans-(1R,2R)-U-50488 hydrochloride. Grades: ≥99% by HPLC. CAS No. 114528-81-3. Molecular formula: C19H26Cl2N2O.HCl. Mole weight: 405.79.
(±)-U-50488 hydrochloride
(±)-U-50488 hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 67197-96-0. Pack Sizes: 25mg. US Biological Life Sciences.
Worldwide
(±)-U-50488 hydrochloride
(±)-U-50488 hydrochloride is a selective κ-opioid agonist with no μ-opioid antagonist effects. (±)-U-50488 hydrochloride blocks Na+ channels at high concentrations. Uses: Analgesics, non-narcotic. Synonyms: (±)-U-50488 hydrochloride; (±)-U 50488 hydrochloride; (±)-U50488 hydrochloride; trans- (±) -3, 4-Dichloro-N-methyl-N-[2- (1-pyrrolidinyl) cyclohexyl]benzeneacetamide hydrochloride. Grades: ≥99% by HPLC. CAS No. 67197-96-0. Molecular formula: C19H26Cl2N2O.HCl. Mole weight: 405.79.
(±)-U-50488 hydrochloride
(±)-U-50488 ((±)-Trans-(1R,2R)-U-50488) hydrochloride is a selective κ opioid receptor (KOR) agonist [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (±)-Trans-(1R,2R)-U-50488 hydrochloride. CAS No. 67197-96-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-15997B.
ICI 199,441 hydrochloride
ICI 199,441 hydrochloride is the hydrochloride salt of ICI 199,441, which is a selective and highly potent κ agonist. It is 146-fold more active than U-50488 in vitro. It has a broad range of effects on the immune system ranging from inflammatory response modulation to opioid and chemokine receptor expression. It has analgesic properties. Synonyms: ICI 199,441 hydrochloride; ICI199,441 hydrochloride; ICI-199,441 hydrochloride; 3,4-Dichloro-N-methyl-N-[(1S)-1-phenyl-2-(1-pyrrolidinyl)ethyl]-benzeneacetamide Monohydrochloride; (S)-3,4-Dichloro-N-methyl-N-[1-phenyl-2-(1-pyrrolidinyl)ethyl]-benzeneacetamide Monohydrochloride; 2-(3,4-Dichlorophenyl)-N-methyl-N-[(1S)-1-phenyl-2-(1-pyrrolidinyl)ethyl]acetamide hydrochloride. Grades: ≥99% by HPLC. CAS No. 115199-84-3. Molecular formula: C21H25Cl3N2O. Mole weight: 427.80.
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