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Blebbistatin blocked myosin II-dependent cell processes. It blocks cell blebbing rapidly and reversibly. Group: Biochemicals. Alternative Names: (+)-1-Phenyl-1,2,3,4-tetrahydro-4-hydroxypyrrolo[2,3-b]-7-methylquinolin-4-one. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences.
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(R)-(+)-Blebbistatin O-Benzoate
A derivative of Blebbistatin. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
(R)-nitro-Blebbistatin
(R)-nitro-Blebbistatin is a more stable form of (+)-blebbistatin, which is the inactive form of (-)-blebbistatin. Prolonged exposure to blue light (450-490 nm) results in degradation of blebbistatin to an inactive product via cytotoxic intermediates, which may be problematic for its use in fluorescent live cell imaging applications. Synonyms: R-(-)-7-Desmethyl-8-nitro Blebbistatin; (3aR)-3a-hydroxy-7-nitro-1-phenyl-2,3-dihydropyrrolo[2,3-b]quinolin-4-one. Grades: ≥98%. CAS No. 1217619-62-9. Molecular formula: C17H13N3O4. Mole weight: 323.3.
Blebbistatin blocked myosin II-dependent cell processes. It blocks cell blebbing rapidly and reversibly. Group: Biochemicals. Alternative Names: (-)-1-Phenyl-1,2,3,4-tetrahydro-4-hydroxypyrrolo[2,3-b]-7-methylquinolin-4-one. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
(-)-Blebbistatin
(-)-Blebbistatin is a cell-permeable inhibitor for non muscle myosin II ATPase with IC50 of ~2 μM, does not inhibit myosin light chain kinase, inhibits contraction of the cleavage furrow without disrupting mitosis or contractile ring assembly. Synonyms: (S)-(-)-Blebbistatin; (S)-blebbistatin; (3aS)-3a-hydroxy-6-methyl-1-phenyl-2,3-dihydropyrrolo[2,3-b]quinolin-4-one. Grades: >98%. CAS No. 856925-71-8. Molecular formula: C18H16N2O2. Mole weight: 292.33.
(-)-Blebbistatin
(-)-Blebbistatin is a selective inhibitor of the ATPase activity of non-muscle myosin II [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 856925-71-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13441.
(+)-Blebbistatin
(+)-Blebbistatin is the inactive enantiomer of Blebbistatin, an inhibitor of myosin II ATPase. (+)-Blebbistatin can be used as a negative control of the active enatiomer (-)-Blebbistatin. Synonyms: (R)-(+)-Blebbistatin; (3aR)-(+)-1,2,3,3a-Tetrahydro-3a-hydroxy-6-methyl-1-phenyl-4H-pyrrolo[2,3-b]quinolin-4-one. Grades: ≥99% by HPLC. CAS No. 1177356-70-5. Molecular formula: C18H16N2O2. Mole weight: 292.34.
(+)-Blebbistatin
(+)-Blebbistatin is the inactive enantiomer of ( - )-Blebbistatin. ( - )-Blebbistatin is a selective inhibitor of myosin II ATPase [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1177356-70-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-107657.
(+)-Blebbistatin
(+)-Blebbistatin. Uses: Designed for use in research and industrial production. Additional or Alternative Names: (3aR)-3a-hydroxy-6-methyl-1-phenyl-2,3-dihydropyrrolo[2,3-b]quinolin-4-one. Product Category: Heterocyclic Organic Compound. Appearance: Yellow solid. CAS No. 1177356-70-5. Molecular formula: C18H16N2O2. Mole weight: 292.3. Purity: ≥98%. IUPACName: (3aR)-3a-hydroxy-6-methyl-1-phenyl-2,3-dihydropyrrolo[2,3-b]quinolin-4-one. Canonical SMILES: CC1=CC2=C(C=C1)N=C3C(C2=O)(CCN3C4=CC=CC=C4)O. Product ID: ACM1177356705. Alfa Chemistry ISO 9001:2015 Certified.
(±)-Blebbistatin
(±)-Blebbistatin is a selective inhibitor of myosin II ATPase. It reversibly blocks cell blebbing, and disrupts directed cell migration and cytokinesis in vertebrate cells; inhibits contraction of the cleavage furrow without disrupting mitosis or contractile ring assembly. Synonyms: Blebbistatin; (±)-1,2,3,3a-Tetrahydro-3a-hydroxy-6-methyl-1-phenyl-4H-pyrrolo[2,3-b]quinolin-4-one. Grades: ≥98% by HPLC. CAS No. 674289-55-5. Molecular formula: C18H16N2O2. Mole weight: 292.34.
Blebbistatin
Blebbistatin is a selective non-muscle myosin II (NMII) inhibitor, promotes directional migration of corneal endothelial cells (CECs) and accelerates wound healing, and better preserves cell junctional integrity and barrier function. Blebbistatin blocks cell migration [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 674289-55-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-13813.
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