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(Rs)-ampa. Uses: Designed for use in research and industrial production. Additional or Alternative Names: (R,S)-2-AMINO-3-(3-HYDROXY-5-METHYL-4-ISOXAZOLYL)PROPIONIC ACID;(RS)-AMPA;(R,S)-A-AMINO-3-HYDROXY-5-METHYL-4-ISOXAZOLEPROPIONIC ACID;(RS)-ALFA-AMINO-3-HYDROXY-5-METHYL-4-ISOXAZOLEPROPIONIC ACID;(RS)-ALPHA-AMINO-3-HYDROXY-5-METHYL-4-ISOXAZOLEPROPIONIC ACID;2-AMINO-3-(3-HYDROXY-5-METHYLISOXAZOL-4-YL)PROPANOIC ACID;(+/-)-ALPHA-AMINO-3-HYDROXY-5-METHYL-4-ISOXAZOLEPROPIONIC ACID;(+/-)-ALPHA-AMINO-3-HYDROXY-5-METHYLISOXAZOLE-4-PROPIONIC ACID HYDRATE. Product Category: Heterocyclic Organic Compound. Appearance: solid. CAS No. 74341-63-2. Molecular formula: C7H10N2O4. Mole weight: 186.17. Product ID: ACM74341632. Alfa Chemistry ISO 9001:2015 Certified. Categories: R. Sampanthan.
(RS)-AMPA
(RS)-AMPA. Group: Biochemicals. Grades: Purified. CAS No. 74341-63-2. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
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(RS)-AMPA
(RS)-AMPA has been found to be a definitive agonist of the AMPA glutamatergic ionotropic receptor. Uses: Excitatory amino acid agonists. Synonyms: (RS)-α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid. Grades: ≥99% by HPLC. CAS No. 74341-63-2. Molecular formula: C7H10N2O4. Mole weight: 186.17.
(RS)-AMPA hydrobromide
(RS)-AMPA hydrobromide. Group: Biochemicals. Grades: Purified. CAS No. 171259-81-7. Pack Sizes: 1mg, 10mg, 50mg. US Biological Life Sciences.
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(RS)-AMPA hydrobromide
The hydrobromide salt form of (RS)-AMPA, which has been found to be an agonist of the excitatory neurotransmitter L-glutamic Acid. Synonyms: (RS)-α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid hydrobromide. Grades: ≥99% by HPLC. CAS No. 171259-81-7. Molecular formula: C7H10N2O4.HBr. Mole weight: 267.08.
4-Isoxazolepropanoicacid,a-amino-2,3-dihydro-5-methyl-3-oxo-. Uses: Designed for use in research and industrial production. Additional or Alternative Names: (RS)-AMPA;(R,S)-A-AMINO-3-HYDROXY-5-METHYL-4-ISOXAZOLEPROPIONIC ACID;(RS)-ALPHA-AMINO-3-HYDROXY-5-METHYL-4-ISOXAZOLEPROPIONIC ACID;(RS)-ALFA-AMINO-3-HYDROXY-5-METHYL-4-ISOXAZOLEPROPIONIC ACID;(R,S)-2-AMINO-3-(3-HYDROXY-5-METHYL-4-ISOXAZOLYL)PROPIONIC ACI. Product Category: Heterocyclic Organic Compound. Appearance: White-to-Off White Powder. CAS No. 77521-29-0. Molecular formula: C7H10N2O4. Mole weight: 186.17. Purity: >99 %. IUPACName: (2S)-2-amino-3-(5-methyl-3-oxo-1,2-oxazol-4-yl)propanoic acid. Canonical SMILES: CC1=C(C(=O)NO1)CC(C(=O)O)N. Density: 1.386 g/cm³. Product ID: ACM77521290. Alfa Chemistry ISO 9001:2015 Certified.
ATPA
ATPA is a potent and selective GluR5 kainate receptor agonist with Ki value of 4.3 nM. It is weakly active at AMPA receptors (GluR1-4), GluR7 and the kainate receptors KA-2. Synonyms: 4-Isoxazolepropanoic acid, α-amino-5-(1,1-dimethylethyl)-2,3-dihydro-3-oxo-; (RS)-2-Amino-3-(3-hydroxy-5-tert-butylisoxazol-4-yl)propanoic acid; α-Amino-5-(1,1-dimethylethyl)-2,3-dihydro-3-oxo-4-isoxazolepropanoic acid; 2-Amino-3-(5-(tert-butyl)-3-hydroxyisoxazol-4-yl)propanoic acid; 2-Amino-3-(5-tert-butyl-3-hydroxy-1,2-oxazol-4-yl)propanoic acid; 2-Amino-3-[3-hydroxy-5-tert-butylisoxazol-4-yl]propanoic acid; (R,S)-ATPA. Grades: ≥98% by HPLC. CAS No. 140158-50-5. Molecular formula: C10H16N2O4. Mole weight: 228.25.
A potent agonist highly selective for GluK1-containing subtype kainate receptors (EC50 = 0.33, 0.80, and 0.38uM for GluK1, GluK1/K2, and GluK1/K5, respectively) over GluK2-containing subtypes (EC50 = 106 and ?uM for GluK2/K5 and GluK2 respectively). Weakly interacts with AMPA receptors (EC50 = 7.6, 7.9 and 22uM for GluA4, GluA3, and GluA1 respectively). Has been used in assessing the functional roles of GluK1-containing subtype kainate receptors in synaptic transmission and plasticity. Group: Biochemicals. Grades: Highly Purified. CAS No. 140158-50-5. Pack Sizes: 1mg. Molecular Formula: C??H??N?O?. US Biological Life Sciences.
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Cl-HIBO
Cl-HIBO is a strongly desensitising and subtype-selective AMPA receptor agonist, which is a heterotetrameric transmembrane receptor and is found in various areas of the brain. It is selective for GluR1 and GluR2 subunit-containing receptors with EC50 values of 4.7 and 1.7 μM for rat recombinant homomeric GluR1 and 2 receptors respectively. It mediates fast synaptic transmission in the central nervous system. Synonyms: 4-Chlorohomoibotenic acid; (RS)-2-Amino-3-(4-chloro-3-hydroxy-5-isoxazolyl)propionic acid; α-Amino-4-chloro-2,3-dihydro-3-oxo-5-isoxazolepropanoic Acid; 2-amino-3-(4-chloro-3-oxo-1,2-oxazol-5-yl)propanoic acid. Grades: ≥99% by HPLC. CAS No. 909400-43-7. Molecular formula: C6H7ClN2O4. Mole weight: 206.59.
UBP 296
UBP 296 is a selective GLUK5 (GluR5)-subunit containing kainate receptor antagonist (apparent KD = 1.09 μM) that displays ~ 90-fold selectivity over AMPA receptors and recombinant human GluR6- and KA2-containing kainate receptors. It has no activity at NMDA or group I mGlu receptors. UBP 296 was shown to selectively block kainate receptor-mediated LTP induction in rat hippocampal mossy fibers. Synonyms: UBP 296; UBP296; UBP-296; (RS)-1-(2-Amino-2-carboxyethyl)-3-(2-carboxybenzyl)pyrimidine-2,4-dione; 2-[[3-(2-amino-2-carboxyethyl)-2,6-dioxopyrimidin-1-yl]methyl]benzoic acid. Grades: ≥98% by HPLC. CAS No. 745055-86-1. Molecular formula: C15H15N3O6. Mole weight: 333.3.
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