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( ( ( ( (2R, 3R, 4S, 5R) -5- (2-Chloro-6- (cyclopentylamino) -9H-purin-9-yl) -4-fluoro-3-hydroxytetrahydrofuran-2-yl) methoxy) (hydroxy) phosphoryl) methyl) phosphonic Acid acts as a modulating agent for 5'-nucleotidase and may be applied to chemotherapeutic and anti-inflammatory treatments. CAS No. 2105903-93-1. Molecular formula: C16H23ClFN5O8P2. Mole weight: 529.78.
( ( ( ( ( ( (2R, 3R, 4S, 5R) -5- (2-Chloro-6- (cyclopentylamino) -9H-purin-9-yl) -4-fluoro-3-hydroxytetrahydrofuran-2-yl) methoxy) (hydroxy) phosphoryl) methyl) phosphoryl) bis (oxy) ) bis (methylene) diisopropyl Dicarbonate may act as a modulating agent for 5'-nucleotidase and may be applied to chemotherapeutic and anti-inflammatory treatments. Group: Biochemicals. Grades: Highly Purified. CAS No. 2105904-27-4. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C26H39ClFN5O14P2, Molecular Weight: 762.01. US Biological Life Sciences.
((2R,3S,5S)-5-(4-amino-2-oxo-1,3,5-triazin-1(2H)-yl)-3-hydroxytetrahydrofuran-2-yl)methyl 4-chlorobenzoate is an impurity of Decitabine, which is a potent inhibitor of DNA methylation. Molecular formula: C15H15ClN4O5. Mole weight: 366.76.
N-(1-((2R,3R,4S)-4-(Bis(4-methoxyphenyl)(phenyl)methoxy)-3-hydroxytetrahydrofuran-2-yl)-2-oxo-1,2-dihydropyrimidin-4-yl)benzamide is a novel and potent pharmaceutical compound utilized in the field of biomedicine to combat abnormal cell growth and malignancies such as cancer. This promising agent exerts its therapeutic effects by modulating key cellular pathways involved in cancer pathogenesis, such as the prevention of cell division and induction of apoptosis. Preclinical investigations have demonstrated the efficacy of this compound against various cancer subtypes, including lung, ovarian and breast cancers. Ongoing research efforts are focused on optimizing the drug's overall pharmacological profile and advancing its development as a clinical therapeutic. Synonyms: N-(1-(4-(Bis(4-methoxyphenyl)(phenyl)methoxy)-3-hydroxytetrahydrofuran-2-yl)-2-oxo-1,2-dihydropyrimidin-4-yl)benzamide. CAS No. 325683-91-8. Molecular formula: C36H33N3O7. Mole weight: 619.66.
Amprenavir and Fosamprenavir intermediate. CAS No. 86087-23-2. Product ID: 2-08344. Molecular formula: C4H8O2. Mole weight: 88.11.
(S)-(+)-3-Hydroxytetrahydrofuran
(S) - ( + ) -3- hydroxytetra hydrofuran. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1g. US Biological Life Sciences.
Worldwide
(S)-(+)-3-Hydroxytetrahydrofuran
(S)-(+)-3-Hydroxytetrahydrofuran. Uses: Designed for use in research and industrial production. Additional or Alternative Names: (S)-TETRAHYDROFURAN-3-OL;(S)-(+)-tetrahyro-3-furanol;3-FURANOL,TETRAHYDRO-,(S);(S)-3-HYDROXytetrahyDROFURAN;(3S)-Tetrahydrofuran-3-ol. Product Category: Furans. Appearance: Clear liquid. CAS No. 86087-23-2. Molecular formula: C4H8O2. Mole weight: 88.11. Purity: 0.97. Density: 1.298. Product ID: ACM86087232. Alfa Chemistry ISO 9001:2015 Certified.
(S)-(+)-3-Hydroxytetrahydrofuran-d4
(S)-(+)-3-Hydroxytetrahydrofuran-d4. Group: Biochemicals. Grades: Highly Purified. CAS No. 1217718-57-4. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
1,3,5-Tri-O-benzoyl-a-D-ribofuranose
1,3,5-Tri-O-benzoyl-a-D-ribofuranose. Uses: Designed for use in research and industrial production. Additional or Alternative Names: (2S,3S,4R,5S)-5-((BENZOYLOXY)METHYL)-3-HYDROXYTETRAHYDROFURAN-2,4-DIYL DIBENZOATE. Appearance: White to off-white powder or crystals. CAS No. 171866-30-1. Molecular formula: C26H22O8. Mole weight: 462.4. Purity: 0.98. Product ID: ACM171866301. Alfa Chemistry ISO 9001:2015 Certified. Categories: 22224-41-5.
1,3,5-Tri-O-benzoyl-a-D-ribofuranose
It is a reagent for nucleosides and is used in the synthesis of antileukemia drug Clofarabine. Synonyms: a-D-Ribofuranose 1,3,5-tribenzoate; 1,3,5-Tribenzoate-α-D-ribofuranose; 1,3,5-Tribenzoate Ribofuranose; α-D-1,3,5-Tri-O-benzoyl-ribofuranose; (2R,3R,4S,5R)-5-(benzoyloxymethyl)-3-hydroxytetrahydrofuran-2,4-diyl dibenzoate. Grades: ≥98% by HPLC. CAS No. 22224-41-5. Molecular formula: C26H22O8. Mole weight: 462.45.
1,3,5-Tri-O-benzoyl-α-D-arabinofuranose
1,3,5-Tri-O-benzoyl-α-D-arabinofuranose, a compound widely used in biomedical industry, exhibits tremendous potential in catalyzing the synthesis of diverse pharmaceuticals, especially nucleoside analogs that exhibit potent activity against viral infections, such as HIV and Hepatitis. Moreover, this versatile compound also serves as a precursor in the synthesis of arabinonucleic acids that possess remarkable attributes in investigating and treating genetic disorders, thereby holding immense promise in a range of therapeutic applications. Synonyms: (2R,3S,4S,5R)-5-((benzoyloxy)methyl)-3-hydroxytetrahydrofuran-2,4-diyl dibenzoate; 1-O,3-O,5-O-Tribenzoyl-alpha-D-arabinofuranose. Grades: ≥95% by HPLC. CAS No. 314289-48-0. Molecular formula: C26H22O8. Mole weight: 462.45.
1,3,5-Tri-O-benzoyl-a-L-ribofuranose
1,3,5-Tri-O-benzoyl-a-L-ribofuranose is a synthetic precursor for the preparation of antiviral agents, particularly for nucleoside analogues involved in HIV research. It's instrumental for ribonucleosides synthesis, necessary in researching numerous diseases. Synonyms: 1-O,3-O,5-O-Tribenzoyl-alpha-L-ribofuranose; α-L-Ribofuranose 1,3,5-tribenzoate; (2S,3S,4R,5S)-5-[(Benzoyloxy)methyl]-3-hydroxytetrahydrofuran-2,4-diyl dibenzoate; 1,3,5-Tris-O-(phenylcarbonyl)-α-L-ribofuranose. Grades: ≥97% by HPLC. CAS No. 171866-30-1. Molecular formula: C26H22O8. Mole weight: 462.45.
2-Amino-2'-deoxyadenosine 5'-triphosphate
2-Amino-2'-deoxyadenosine 5'-triphosphate, a crucial compound extensively employed in the biomedical sector, plays a pivotal role as a DNA polymerase substrate, facilitating the intricate processes of DNA replication and repair. Remarkably, it partakes in synthesizing indispensable DNA and RNA molecules, fundamentally contributing to a myriad of cellular mechanisms. Its significance transcends biological boundaries as it finds profound utility in drug development endeavors aimed at combatting DNA-associated ailments, including cancer and genetic disorders. Synonyms: [[(2R,3S,5R)-5-(2,6-diaminopurin-9-yl)-3-hydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate; Ddaptp; (((2R,3S,5R)-5-(2,6-Diamino-9H-purin-9-yl)-3-hydroxytetrahydrofuran-2-yl)methyl)triphosphoric acid; 2-NH2-Datp; 2-Amino-2'-deoxyadenosine 5'-triphosphate; 2-amino-2' deoxyadenosine 5'-triphosphate; 2,6-Diaminopurine deoxyribonucleoside triphosphate; Boc-(R)-3-Amino-3-(3-nitro-phenyl)-propionicacid; Adenosine 5'-(tetrahydrogen triphosphate), 2-amino-2'-deoxy-; 9-[2-Deoxy-5-O- (hydroxy{[hydroxy (phosphonooxy) phosphoryl]oxy}phosphoryl) pentofuranosyl]-2-imino-2, 9-dihydro-1H-purin-6-amine. CAS No. 81503-63-1. Molecular formula: C10H17N6O12P3. Mole weight: 506.20.
2-Aminopurine-2'-deoxyriboside-Triphosphate
2-Aminopurine-2'-deoxyriboside-Triphosphate is a crucial component in biomedical research for studying genetic mutations and diseases. It is commonly used as a substrate for DNA polymerases and DNA sequencing techniques. This nucleotide analogue assists in detecting and characterizing mutations, including those related to cancer and genetic disorders, providing valuable insights for drug development and personalized medicine. Synonyms: 2-Aminopurine-drTP; 9-(2-Deoxy-5-O-(hydroxy((hydroxy(phospho nooxy)phosphinyl)oxy)phophinyl)-beta-D-erythro-pentofuranosyl)-9H-purin-2-amine; 1-(2-Amino-9H-purine-9-yl)-1,2-dideoxy-beta-D-erythro-pentofuranose 5-triphosphoric acid; (((2R,3S,5R)-5-(2-amino-9H-purin-9-yl)-3-hydroxytetrahydrofuran-2-yl)methyl)triphosphoric acid. Grades: ≥90% by AX-HPLC. CAS No. 26666-45-5. Molecular formula: C10H16N5O12P3. Mole weight: 491.10.
2'-Bromo-2'-deoxy-3'-O-methanesulfonyluridine
2'-Bromo-2'-deoxy-3'-O-methanesulfonyluridine is a remarkable antiviral compound employed in the research of diverse viral afflictions, encompassing herpes simplex and Epstein-Barr virus infections. It exhibits its efficacy by thwarting viral replication via its assimilation into viral DNA and consequential cessation of DNA chain elongation. Synonyms: 5-Bromo-2'-deoxyuridine 5'-triphosphate sodium salt; Brdutp; 102212-99-7; [[(2R,3S,5R)-5-(5-bromo-2,4-dioxopyrimidin-1-yl)-3-hydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate; Bromodeoxyuridine triphosphate; Uridine5'-(tetrahydrogen triphosphate), 5-bromo-2'-deoxy-, tetrasodium salt (9CI); 5-Bromodeoxyuridine triphosphate; 5-BrdUTP; 5-bromo-2'-deoxyuridine 5'-triphosphate; SCHEMBL150029; DTXSID30940203; MFCD00057405; PD148794; J-000655; Uridine 5'-(tetrahydrogen triphosphate), 5-bromo-2'-deoxy-; ((2R,3S,5R)-5-(5-bromo-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3-hydroxytetrahydrofuran-2-yl)methyl tetrahydrogen triphosphate; 5-Bromo-1-[2-deoxy-5-O- (hydroxy{[hydroxy (phosphonooxy) phosphoryl]oxy}phosphoryl) pentofuranosyl]-4-hydroxypyrimidin-2 (1H) -one. CAS No. 18736-53-3. Molecular formula: C9H14BrN2O14P3. Mole weight: 547.04.
2'-Deoxy-2'-fluoroadenosine-5'-diphosphate
2'-Deoxy-2'-fluoroadenosine-5'-diphosphate, an indispensable tool in the biomedical industry, exhibits versatile applications in the synthesis of RNA-targeting antiviral drugs. This vital compound serves as a significant precursor, thwarting viral replication and manifesting its potential to combat RNA virus-induced ailments such as respiratory viral infections and viral hepatitis. Synonyms: 2'-deoxy-2'-fluoroadenosine 5'-(trihydrogen diphosphate); 2'-DE-2'-Fladdp; ((2R,3R,4R,5R)-5-(6-Amino-9H-purin-9-yl)-4-fluoro-3-hydroxytetrahydrofuran-2-yl)methyl trihydrogen diphosphate; 2'-Deoxy-2'-fluoroadenosine 5'-diphosphate; SCHEMBL9394807; DTXSID80987906; Adenosine 5'-(trihydrogen diphosphate), 2'-deoxy-2'-fluoro-; 9-{2-Deoxy-2-fluoro-5-O-[hydroxy (phosphonooxy) phosphoryl]pentofuranosyl}-9H-purin-6-amine. CAS No. 68357-16-4. Molecular formula: C10H14FN5O9P2. Mole weight: 429.19.
2'-Deoxy-2'-fluoroadenosine 5'-Triphosphate
2'-Deoxy-2'-fluoroadenosine 5'-Triphosphate: A highly significant and invaluable modified nucleotide employed extensively in the fields of biochemistry and molecular biology for groundbreaking research purposes. Renowned for its pivotal role in the exploration of DNA replication, transcription, and translation mechanisms, this extraordinary compound serves as an indispensable tool. Its application spans across multifaceted investigations pertaining to drug resistance mechanisms, mutagenesis, and groundbreaking advancements in cancer research. Synonyms: (((2R,3R,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-fluoro-3-hydroxytetrahydrofuran-2-yl)methyl)triphosphoric acid; Adenosine 5'-(tetrahydrogen triphosphate), 2'-deoxy-2'-fluoro-; 2'-Fluoro-2'-deoxyadenosine-5'-triphosphate; 2'-Deoxy-2'-fluoroadenosine 5'-(tetrahydrogen triphosphate); 2'-FdATP. Grades: ≥95% by HPLC. CAS No. 73449-07-7. Molecular formula: C10H15FN5O12P3. Mole weight: 509.17.
2'-Deoxy-5-methyl-isocytidine triphosphate
2'-Deoxy-5-methyl-isocytidine triphosphate, a paramount substance in the realm of biomedical research, serves as an indispensable component for synthesizing intricate DNA and RNA molecules. Its significance lies in its role as a substrate for DNA polymerases, thereby assuming a pivotal position in an array of molecular biology methodologies encompassing PCR, DNA sequencing, and mutagenesis investigations. Synonyms: 4(1H)-Pyrimidinone, 2-amino-1-[2-deoxy-5-O-[hydroxy[[hydroxy (phosphonooxy) phosphinyl]oxy]phosphinyl]-β -D-erythro-pentofuranosyl]-5-methyl-; 2-Amino-1-[2-deoxy-5-O-[hydroxy[[hydroxy (phosphonooxy) phosphinyl]oxy]phosphinyl]-β -D-erythro-pentofuranosyl]-5-methyl-4 (1H) -pyrimidinone; ((2R,3S,5R)-5-(2-amino-5-methyl-4-oxopyrimidin-1(4H)-yl)-3-hydroxytetrahydrofuran-2-yl)methyl tetrahydrogen triphosphate; 2'-Deoxy-5-methylisocytidine 5'-triphosphoric acid. CAS No. 139157-80-5. Molecular formula: C10H18N3O13P3. Mole weight: 481.18.
2'-Deoxyadenosine-5'-diphosphate trisodium salt
2'-Deoxyadenosine-5'-diphosphate trisodium salt, a compound widely used in the realm of biomedicine, boasts a unique chemical composition that enables its versatile application in both research and clinical contexts. With its efficacy as both a DNA synthesis and repair agent in addition to its potential as a treatment option for conditions like anemia and blood disorders, this remarkable biochemical substance remains of critical importance to the field of biomedicine. Synonyms: sodium ((2R,3S,5R)-5-(6-amino-9H-purin-9-yl)-3-hydroxytetrahydrofuran-2-yl)methyl diphosphate; Adenosine 5'-(trihydrogen diphosphate), 2'-deoxy-, trisodium salt; Trisodium 2'-deoxy-5'-O-[ (phosphonatooxy) phosphinato]adenosine. Grades: ≥97% by HPLC. CAS No. 402491-35-4. Molecular formula: C10H12N5Na3O9P2. Mole weight: 477.15.
2'-Deoxyadenosine-5'-monophosphate (dAMP)
2-Deoxyadenosine 5Monophosphate is the first nucleotide of the phi 29 DNA. Group: Biochemicals. Alternative Names: 2'-Deoxyadenosine 5'-(Dihydrogen Phosphate); 2'-Deoxy-5'-AMP; 2'-Deoxy-5'-adenylic Acid; 2'-Deoxy-AMP; 2'-Deoxyadenosine 5'-Monophosphate; 2'-Deoxyadenosine 5'-Phosphate; 2'-Deoxyadenylic Acid; 5'-dAMP; Deoxy-AMP; Deoxyadenosine 5'-Monophosphate; Deoxyadenosine 5'-Phosphate; Deoxyadenosine Monophosphate; Deoxyadenylic Acid; NSC 77680; NSC 82625; PdA; dAMP; ((2R,3S,5R)-5-(6-Amino-9H-purin-9-yl)-3-hydroxytetrahydrofuran-2-yl)methyl dihydrogen Phosphate. Grades: Highly Purified. CAS No. 653-63-4. Pack Sizes: 1g, 5g. Molecular Formula: C??H??N?O?P, Molecular Weight: 331.22. US Biological Life Sciences.
Worldwide
2'-Deoxyadenosine-5'-monophosphate disodium salt
2'-Deoxyadenosine-5'-monophosphate disodium salt, a pivotal biochemical compound, finds significance in DNA and RNA synthesis. It displays its profound potential as a nucleotide analogue, contributing extensively to the management of diverse ailments such as viral infections and select malignancies. With improved stability and solubility attributed to its disodium salt form, this compound emerges as an optimal preference within the biomedical realm, particularly for research and pharmaceutical purposes. Synonyms: Sodium ((2R,3S,5R)-5-(6-amino-9H-purin-9-yl)-3-hydroxytetrahydrofuran-2-yl)methyl phosphate; 5'-Adenylic acid, 2'-deoxy-, disodium salt; dAMP.2Na; 2'-Deoxyadenosine 5'-phosphoric acid disodium salt. Grades: ≥97% by HPLC. CAS No. 2922-74-9. Molecular formula: C10H12N5Na2O6P. Mole weight: 375.19.
2'-Deoxyadenosine 5'-monophosphate sodium salt
2'-Deoxyadenosine 5'-monophosphate sodium salt is a vital biomolecule extensively utilized in the biomedical sector, playing a pivotal role in DNA synthesis and repair, thereby occupying an indispensable position in gene expression. Leveraging its sodium salt manifestation, this compound exhibiting amplified solubility and stability. Synonyms: 2'-Deoxyadenylic acid; dAMP Na; Sodium ((2R,3S,5R)-5-(6-amino-9H-purin-9-yl)-3-hydroxytetrahydrofuran-2-yl)methyl phosphate. Grades: ≥ 99% (HPLC). CAS No. 151151-31-4. Molecular formula: C10H14N5O6P·xNa. Mole weight: 331.22 (free acid).
2'-Deoxyadenosine-5'-triphosphate disodium salt
2'-Deoxyadenosine-5'-triphosphate disodium salt is a pivotal recompound widely employed in biomedical research, presenting itself as an indispensable constituent for the intricate process of DNA research and development. This invaluable component finding its purpose in the realm of sequence-specific DNA manipulation techniques, including the illustrious procedures of PCR and DNA sequencing. Remarkably, it assuming the role of a substrate for DNA polymerases, affordably fostering the genes' amplification to facilitate subsequent analysis. Notably, the disodium salt incarnation of this compound showcasing enhanced stability and solubility traits, further augmenting its scientific merit. Synonyms: 5'-dATP 2Na; Sodium ((2R,3S,5R)-5-(6-amino-9H-purin-9-yl)-3-hydroxytetrahydrofuran-2-yl)methyl dihydrogentriphosphate. Grades: 98%. CAS No. 74299-50-6. Molecular formula: C10H14N5O12P3Na2. Mole weight: 535.15.
2'-Deoxycytidine-5'-diphosphate
2'-Deoxycytidine-5'-diphosphate is a pivotal compound extensively employed in the biomedical field, serving as an indispensable entity pertaining to cellular metabolism, predominantly concerning DNA research and development and repair. This compound primarily engages in the research of diverse ailments correlated with DNA impairment, encompassing malignancies, hereditary anomalies, and viral invasions. Synonyms: dCDP; Deoxycytidine diphosphate; 2'-deoxycytidine diphosphate; Deoxy-CDP; 2'-deoxycytidine 5'-(trihydrogen diphosphate); delta-1beta-Ribofuranosylcytosine diphosphate; ((2R,3S,5R)-5-(4-Amino-2-oxopyrimidin-1(2H)-yl)-3-hydroxytetrahydrofuran-2-yl)methyl trihydrogen diphosphate; 4-amino-1-[2-deoxy-5-O-[hydroxy(phosphonooxy)phosphinyl]-beta-D-erythro-pentofuranosyl]-2(1H)-pyrimidinone; 2'-Deoxy-CDP. Grades: ≥98% by HPLC. CAS No. 800-73-7. Molecular formula: C9H15N3O10P2. Mole weight: 387.18.
2'-Deoxycytidine-5'-triphosphate sodium salt
2'-Deoxycytidine-5'-triphosphate sodium salt is an indispensable nucleotide analog fundamental to the biomedical sector, exhibiting paramount significance in the realms of DNA research and development and metabolism. Molecular biology research, DNA sequencing, and polymerase chain reaction (PCR) experiments frequently rely on this pivotal compound. By serving as a fundamental constituent for DNA replication, it assuming a critical role in the exploration of genetic mutations, genomics, and the advancement of pharmaceutical interventions against manifold ailments. Synonyms: dCTP sodium salt; 2'-Deoxycytidine-5'-triphosphoric acid trisodium salt; Cytidine 5'-(tetrahydrogen triphosphate), 2'-deoxy-, trisodium salt; sodium ((2R,3S,5R)-5-(4-amino-2-oxopyrimidin-1(2H)-yl)-3-hydroxytetrahydrofuran-2-yl)methyl hydrogentriphosphate; 2'-Deoxy CTP trisodium salt. Grades: ≥98% by HPLC. CAS No. 109909-44-6. Molecular formula: C9H13N3Na3O13P3. Mole weight: 533.10.
2'-Deoxycytidyl-(3'-5')-2'-deoxyguanosine
2'-Deoxycytidyl-(3'-5')-2'-deoxyguanosine, a nucleoside analogue, is a potent antiviral drug utilized by the biomedical industry to combat the insidious Hepatitis B and C viruses. Its mode of action lies in its inhibitory nature, as it halts viral RNA from reverse transcribing into DNA, effectively impeding transmission and replication of the virus. Synonyms: dCpdG; [5-(2-amino-6-oxo-3H-purin-9-yl)-3-hydroxyoxolan-2-yl]methyl [5-(4-amino-2-oxopyrimidin-1-yl)-2-(hydroxymethyl)oxolan-3-yl] hydrogen phosphate,azane; DCPDG Ammonium Salt; (2R,3S,5R)-5-(4-amino-2-oxopyrimidin-1(2H)-yl)-2-(hydroxymethyl)tetrahydrofuran-3-yl((2R,3S,5R)-5-(2-amino-6-oxo-1H-purin-9(6H)-yl)-3-hydroxytetrahydrofuran-2-yl)methyl hydrogen phosphate,ammonia salt. CAS No. 77710-57-7. Molecular formula: C19H25N8O10P·NH3. Mole weight: 573.45.
2'-Deoxyguanosine-5'-triphosphate trisodium salt
dGTP is a stable nucleotide used in the in vivo synthesis of DNA. Synonyms: 2'-Deoxyguanosine 5'-triphosphoric acid trisodium salt; dGTP.3Na; dGTP trisodium salt; sodium ((2R,3S,5R)-5-(2-amino-6-oxo-1H-purin-9(6H)-yl)-3-hydroxytetrahydrofuran-2-yl)methyl hydrogentriphosphate; 2'-Deoxyguanosine 5'-(tetrahydrogen triphosphate) trisodium salt. Grades: ≥98% by HPLC. CAS No. 93919-41-6. Molecular formula: C10H13N5Na3O13P3. Mole weight: 573.13.
2'-Deoxyuridine-5'-diphosphate
2'-Deoxyuridine-5'-diphosphate (dUDP) reigns as a paramount bioactive compound, assuming a pivotal function within the panorama of DNA research and development, wherein its utilization transpires during the advancement of antiviral therapeutic compounds. Synonyms: Deoxyuridine diphosphate; Uridine 5'-(trihydrogen diphosphate), 2'-deoxy-; 2'-deoxyuridine 5'-(trihydrogen diphosphate); ((2R,3S,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3-hydroxytetrahydrofuran-2-yl)methyl trihydrogen diphosphate; 2,4(1H,3H)-pyrimidinedione, 1-[2-deoxy-5-O-[hydroxy(phosphonooxy)phosphinyl]-beta-D-erythro-pentofuranosyl]-; dUDP. Grades: ≥95%. CAS No. 4208-67-7. Molecular formula: C9H14N2O11P2. Mole weight: 388.16.
2'-Deoxyuridine-5'-diphosphate trisodium salt
2'-Deoxyuridine-5'-diphosphate trisodium salt, an essential component in the DNA synthesis process, boasts multifaceted medicinal applications. Notably, it serves as an effective treatment for hyperuricemia and gout, alongside combatting viral infections such as herpes and varicella-zoster. Additionally, it's a potent reagent for DNA sequencing and labeling studies, exemplifying its versatility and necessity in the field of biological research. Synonyms: Sodium ((2R,3S,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3-hydroxytetrahydrofuran-2-yl)methyl diphosphate; Trisodium 2'-deoxy-5'-O-[ (phosphonatooxy)phosphinato]uridine; Uridine, 2'-deoxy-, 5'-(trihydrogen diphosphate), sodium salt (1:3). Grades: ≥97% by HPLC. Molecular formula: C9H11N2Na3O11P2. Mole weight: 454.11.
2'-Deoxyuridine-5'-monophosphate
Deoxyuridine monophosphate (dUMP), also known as deoxyuridylic acid or deoxyuridylate in its conjugate acid and conjugate base forms, respectively, is a deoxynucleotide. It is an intermediate in the metabolism of deoxyribonucleotides. DUMP is a pyrimidine 2'-deoxyribonucleoside 5'-monophosphate having uracil as the nucleobase. It has a role as a metabolite, an Escherichia coli metabolite and a mouse metabolite. Synonyms: 2'-Deoxy-5'-uridylic acid; dUMP; Deoxyuridine monophosphate; 2'-deoxyuridylic acid; Deoxyuridylic acid; Uridine, 2'-deoxy-, 5'-(dihydrogen phosphate); 2,4(1H,3H)-pyrimidinedione, 1-(2-deoxy-5-O-phosphono-beta-D-erythro-pentofuranosyl)-; ((2R,3S,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3-hydroxytetrahydrofuran-2-yl)methyl dihydrogen phosphate. Grades: ≥95%. CAS No. 964-26-1. Molecular formula: C9H13N2O8P. Mole weight: 308.18.
2'-Deoxyuridine 5'-monophosphate disodium salt
2'-Deoxyuridine 5'-monophosphate disodium salt is an indispensable precursor within the nucleotide research and development pathway, assuming a pivotal role in facilitating the comprehension of intricate DNA replication and repair mechanisms. Synonyms: dUMP disodium salt; Disodium 2'-deoxyuridylate; sodium ((2R,3S,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3-hydroxytetrahydrofuran-2-yl)methyl phosphate; 5'-Uridylic acid, 2'-deoxy-, disodium salt; 2'-dUMP.2Na. Grades: ≥95% by HPLC. CAS No. 42155-08-8. Molecular formula: C9H11N2Na2O8P. Mole weight: 352.15.
2'-Deoxy-uridine 5'-(O-Phenyl Carbonothioate)
2'-Deoxy-uridine 5'-(O-Phenyl Carbonothioate) is an intermediate in synthesizing 5'O,6-Cyclo-dihydro-2',2'-difluoro-2'-deoxyuridine, Gemcitabine Hydrochloride impurity (a product of degradation) which is an antineoplastic agent. Synonyms: O-(((2R,3S,5R)-5-(2,4-Dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3-hydroxytetrahydrofuran-2-yl)methyl) O-Phenyl Carbonothioate. Molecular formula: C16H16N2O6S. Mole weight: 364.37.
2'-Deoxyuridine 5'-triphosphate
2'-Deoxyuridine 5'-triphosphate, a nucleotide analog, is utilized in DNA synthesis and repair. The drug finds wide application in treating viral infections, most notably herpes and HIV. Administration of this drug leads to the termination of chain growth and subsequent inhibition of viral replication. It is a substrate for DNA polymerase and is incorporated during DNA chain elongation. Such incorporation plays a significant role in the fight against virally induced diseases. Synonyms: 2'-Deoxyuridine-5'-Triphosphoric Acid; Deoxyuridine triphosphate; deoxy-UTP; dUTP; Deoxyuridine-5'-Triphosphate; 2'-deoxyuridine 5'-(tetrahydrogen triphosphate); Uridine 5'-(tetrahydrogen triphosphate), 2'-deoxy-; ((2R,3S,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3-hydroxytetrahydrofuran-2-yl)methyl tetrahydrogen triphosphate. Grades: 95%. CAS No. 1173-82-6. Molecular formula: C9H15N2O14P3. Mole weight: 468.14.
3'-O-tert-Butyldimethylsilyl-5'-O-DMT-uridine
It is used for special nucleoside or RNA modification. Synonyms: 5'-O-DMT-3'-O-TBDMS uridine; 5'-O-(4,4'-Dimethoxytrityl)-3'-O-t-butyldimethylsilyl uridine; 3'-O-(tert-Butyldimethylsilyl)-5'-O-(4,4'-dimethoxytrityl)uridine; 1- ( (2R, 3R, 4S, 5R)-5- ( (Bis (4-methoxyphenyl) (phenyl)methoxy)methyl)-4- ( (tert-butyldimethylsilyl)oxy)-3-hydroxytetrahydrofuran-2-yl)pyrimidine-2, 4 (1H, 3H)-dione; 5'-O-[Bis(4-methoxyphenyl)phenylmethyl]-3'-O-[(1,1-dimethylethyl)dimethylsilyl]uridine; 5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-3'-O-[dimethyl(2-methyl-2-propanyl)silyl]uridine. Grades: ≥95%. CAS No. 81246-81-3. Molecular formula: C36H44N2O8Si. Mole weight: 660.83.
5-Aminoallyl-2'-deoxyuridine 5'-triphosphate, labeled with 5/6-TAMRA
5-Aminoallyl-2'-deoxyuridine 5'-triphosphate, labeled with 5/6-TAMRA is a vital tool in the biomedical industry for DNA modification. This product finds application in fluorescent labeling of nucleotides during PCR or DNA sequencing processes. It allows for accurate detection and visualization of DNA sequences, aiding in disease diagnosis, drug discovery, and genetic research. Synonyms: (((2R,3S,5R)-5-(5-((E)-3-(3',6'-bis(dimethylamino)-3-oxo-3H-spiro[isobenzofuran-1,9'-xanthene]-6-carboxamido)prop-1-en-1-yl)-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3-hydroxytetrahydrofuran-2-yl)methyl)triphosphoric acid. Grades: 95%. CAS No. 151345-35-6. Molecular formula: C37H40N5O18P3. Mole weight: 935.66 (free acid).
5-Aza-2'-deoxy Cytidine Diphosphate
5-Aza-2'-deoxy Cytidine Diphosphate is a derivative of Decitabine, which is a potent inhibitor of DNA methylation used to treat myelodysplastic syndromes (MDS). Synonyms: ((2R,3S,5R)-5-(4-amino-2-oxo-1,3,5-triazin-1(2H)-yl)-3-hydroxytetrahydrofuran-2-yl)methyl trihydrogen diphosphate; 4-Amino-1-(2-deoxy-β-D-erythro-pentofuranosyl)-1,3,5-triazin-2(1H)-one Diphosphate; 2-Desoxy-5-azacytidine Diphosphate; 2'-Deoxy-5-azacytidine Diphosphate; DAC Diphosphate; Dacogen Diphosphate; Decitabine Diphosphate; NSC 127716 Diphosphate; β-Decitabine Diphosphate; 4-Amino-1-{2-deoxy-5-O-[hydroxy(phosphonooxy)phosphoryl]-β-D-erythro-pentofuranosyl}-1,3,5-triazin-2(1H)-one. Molecular formula: C8H14N4O10P2. Mole weight: 388.16.
5-Bromo-2'-deoxy-2',2'-difluorouridine 5'-O-Acetate is an intermediate in synthesizing 5'O,6-Cyclo-dihydro-2',2'-difluoro-2'-deoxyuridine, which is an impurity (a product of degradation) of Gemcitabine Hydrochloride which is an antineoplastic agent. Synonyms: ((2R,3R,5R)-5-(5-Bromo-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4,4-difluoro-3-hydroxytetrahydrofuran-2-yl)methyl Acetate. Molecular formula: C11H11BrF2N2O6. Mole weight: 385.12.
5'-O-(4,4-Dimethoxytrityl)-3'-deoxy-5-methyluridine, a compound of immense significance in the biomedical realm, assumes a pivotal function in RNA synthesis in the context of drug exploration and scholarly investigation. Synonyms: 5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-3'-deoxy-5-methyluridine; 5-O-(4,4'-dimethoxytrityl)-1,3-dideoxy-1-thymin-1-yl-beta-D-erythro-pentofuranose; 3'-Deoxy-5'-O-(dimethoxytrityl)-5-methyluridine; 5'-O-(Dimethoxytrityl)-5-methyl-3'-deoxyuridine; 1- ( (2R, 3R, 5S)-5- ( (bis (4-methoxyphenyl) (phenyl)methoxy)methyl)-3-hydroxytetrahydrofuran-2-yl)-5-methylpyrimidine-2, 4 (1H, 3H)-dione. Grades: ≥95%. CAS No. 143653-61-6. Molecular formula: C31H32N2O7. Mole weight: 544.59.
5'-O-(Dimethoxytrityl)-5-methyl-3'-deoxyuridine
5'-O-(Dimethoxytrityl)-5-methyl-3'-deoxyuridine, commonly known as DMDU, stands as a paramount compound within the biomedicine realm. Its application in the synthesis of nucleoside analogs holds immense significance, fostering the advancement of antiviral and anticancer drugs. Through the inhibition of DNA replication, DMDU assists in grappling with viral infections such as HIV and diverse malignancies. Synonyms: 3'-Deoxy-5'-O-(dimethoxytrityl)-5-methyluridine; 114551-15-4; 1-[(2R,3R,5S)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-3-hydroxyoxolan-2-yl]-5-methylpyrimidine-2,4-dione; DTXSID901170479; 3/'-DEOXY-5/'-O-(DIMETHOXYTRITYL)-5-METHYLURIDINE; 5'-O-[Bis(4-methoxyphenyl)phenylmethyl]-3'-deoxy-5-methyluridine; 1- ( (2R, 3R, 5S)-5- ( (bis (4-methoxyphenyl) (phenyl)methoxy)methyl)-3-hydroxytetrahydrofuran-2-yl)-5-methylpyrimidine-2, 4 (1H, 3H)-dione. Grades: ≥ 95%. CAS No. 114551-15-4. Molecular formula: C31H32N2O7. Mole weight: 544.49.
Brivudine 5'-Triphosphate Ammonium
Brivudine 5'-Triphosphate Ammonium Salt is derived from Brivudine, which is a nucleoside analog which causes induction of neuronal differentiation in human reporter cell lines and adult stem cells. Anti-herpes medication. Synonyms: 5-(2-Bromovinyl)-2'-deoxyuridine-5'-triphosphate; [[(2R,3S,5R)-5-[5-[(E)-2-bromoethenyl]-2,4-dioxopyrimidin-1-yl]-3-hydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate; Uridine 5'-(tetrahydrogen triphosphate), 5-(2-bromoethenyl)-2'-deoxy-, (E)-; BVdUTP; BV(5)Dutp; Bvdu-tp; SCHEMBL442341; SCHEMBL442343; CHEMBL4594370; (E)-5-(2-Bromovinyl)-dUTP; Brivudine 5'-Triphosphate Ammonium; E-5-Bromovinyl-2'-deoxyuridine triphosphate; (E)-5-(2-Bromovinyl)-2'-deoxyuridine triphosphate; (e)-5-(2-bromovinyl)-2'-deoxyuridine 5'-triphosphate; Uridine 5'-(tetrahydrogen triphosphate), 5-[(1E)-2-bromoethenyl]-2'-deoxy-; ((2R,3S,5R)-5-(5-((E)-2-Bromovinyl)-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3-hydroxytetrahydrofuran-2-yl)methyl tetrahydrogen triphosphate; [[(2R,3S,5R)-5-[5-[(E)-2-bromovinyl]-2,4-dioxo-pyrimidin-1-yl]-3-hydroxy-tetrahydrofuran-2-yl]methoxy-hydroxy-phosphoryl] phosphono hydrogen phosphate. Molecular formula: C11H16BrN2O14P3. Mole weight: 573.08.
Diquafosol Impurity 21
Diquafosol Impurity 21. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: sodium ((2R,3S,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3-hydroxytetrahydrofuran-2-yl)methyl hydrogentriphosphate. CAS No. 102814-08-4. Molecular formula: C9H12N2Na3O14P3. Mole weight: 534.09. Catalog: APB102814084.
Diquafosol Impurity 23
Diquafosol Impurity 23. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: sodium ((2R,3S,5R)-5-(4-amino-2-oxo-3,4-dihydropyrimidin-1(2H)-yl)-3-hydroxytetrahydrofuran-2-yl)methyl hydrogentriphosphate. CAS No. 102783-51-7. Molecular formula: C9H15N3Na3O13P3. Mole weight: 535.12. Catalog: APB102783517.
Gemcitabine 5'-elaidate
Gemcitabine 5'-elaidate. Group: Biochemicals. Alternative Names: (E)-((2R,3R,5R)-5-(4-Amino-2-oxopyrimidin-1(2H)-yl)-4,4-difluoro-3-hydroxytetrahydrofuran-2-yl)methyl octadec-9-enoate; 2'-Deoxy-2',2'-difluorocytidine 5'-(9E)-9-octadecenoate; CP-4126; LVT derivative of Gemcitabine; CO-101. Grades: Highly Purified. CAS No. 210829-30-4. Pack Sizes: 500mg, 1g, 2g, 5g, 10g. Molecular Formula: C27H43F2N3O5. US Biological Life Sciences.
N2-iso-Butyroyl-5'-O-(4,4'-dimethoxytrityl)-3'-deoxy-3'-fluoroguanosine, a biomedical compound, demonstrates its effectiveness in targeting and treating specific diseases. Its therapeutic potential and precise mechanism of action can be explored through the referenced websites, providing comprehensive information concerning drug interactions and its efficacy in addressing various medical conditions. Synonyms: 5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-3'-deoxy-3'-fluoro-N-isobutyrylguanosine; Guanosine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-3'-deoxy-3'-fluoro-N-(2-methyl-1-oxopropyl)-; N- (9- ( (2R, 3S, 4S, 5R)-5- ( (bis (4-methoxyphenyl) (phenyl)methoxy)methyl)-4-fluoro-3-hydroxytetrahydrofuran-2-yl)-6-oxo-6, 9-dihydro-1H-purin-2-yl)isobutyramide. Grades: ≥95%. CAS No. 2080404-19-7. Molecular formula: C35H36FN5O7. Mole weight: 657.69.
N4-Acetyl-3'-O-tert-butyldimethylsilyl-5'-O-DMT-cytidine is a cutting-edge and technologically advanced biomedical compound aiding in studying an extensive array of debilitating diseases. Synonyms: 5'-DMT-3'-TBDMS-Ac-rC; N- (1- ( (2R, 3R, 4S, 5R)-5- ( (Bis (4-methoxyphenyl) (phenyl)methoxy)methyl)-4- ( (tert-butyldimethylsilyl)oxy)-3-hydroxytetrahydrofuran-2-yl)-2-oxo-1, 2-dihydropyrimidin-4-yl)acetamide; 3'-O-t-Butyldimethylsilyl-5'-O-(4,4'-dimethoxytrityl)-N4-acetyl cytidine; 3'-O-TBDMS-5'-O-DMT-N4-Ac cytidine. Grades: 98%. CAS No. 123956-65-0. Molecular formula: C38H47N3O8Si. Mole weight: 701.88.
N4-Benzoyl-3'-deoxy-5'-O-DMT-cytidine
N4-Benzoyl-3'-deoxy-5'-O-DMT-cytidine is a potent nucleoside analog used in biomedicine to target specific viral infections and cancer cells. By inhibiting DNA replication and cell division, it effectively treats viral infections caused by herpes simplex virus and varicella-zoster virus. Additionally, it demonstrates anti-cancer activity by suppressing tumor growth and inducing apoptosis in various cancer types. Its specificity and efficacy make it a valuable tool in the biomedical field for research and potential therapeutic applications. Synonyms: N4-Benzoyl-3'-deoxy-5'-O-DMT-D-cytidine; N4-Benzoyl-5'-O-(4,4-dimethoxytrityl)-3'-deoxycytidine; N-Benzoyl-5'-O-(dimethoxytrityl)-3'-deoxycytidine; N-Benzoyl-5'-O-[bis(4-methoxyphenyl)(phenyl)methyl]-3'-deoxycytidine; N- (1- ( (2R, 3R, 5S)-5- ( (bis (4-methoxyphenyl) (phenyl)methoxy)methyl)-3-hydroxytetrahydrofuran-2-yl)-2-oxo-1, 2-dihydropyrimidin-4-yl)benzamide; N4-Benzoyl-5'-O-DMT-3'-deoxycytidine. Grades: ≥95%. CAS No. 86234-45-9. Molecular formula: C37H35N3O7. Mole weight: 633.69.
N6-Benzoyl-5'-O-(dimethoxytrityl)-3'-deoxyadenosine is an essential constituent in the biomedical sector, acting as a fundamental precursor in the amalgamation of diverse pharmaceutics and investigative substances. This compound notably contributes to advancing the development of antiviral drugs. Synonyms: N6-Benzoyl-5'-O-(4,4-dimethoxytrityl)-3'-deoxyadenosine; N6-Benzoyl-3'-deoxy-5'-O-DMT-adenosine; N-Benzoyl-5'-O-[bis(4-methoxyphenyl)(phenyl)methyl]-3'-deoxyadenosine; N- (9- ( (2R, 3R, 5S)-5- ( (Bis (4-methoxyphenyl) (phenyl)methoxy)methyl)-3-hydroxytetrahydrofuran-2-yl)-9H-purin-6-yl)benzamide. Grades: ≥95%. CAS No. 84138-86-3. Molecular formula: C38H35N5O6. Mole weight: 657.71.
(R)-(-)-3-Hydroxytetrahydrofuran
(R)-(-)-3-Hydroxytetrahydrofuran. Uses: Designed for use in research and industrial production. Additional or Alternative Names: (R)-(-)-Tetrahydro-3-furanol. Product Category: Furans. CAS No. 86087-24-3. Molecular formula: C4H8O2. Mole weight: 88.11. Purity: 0.98. Density: 1.09 g/mL at 25 °C(lit.). Product ID: ACM86087243. Alfa Chemistry ISO 9001:2015 Certified.
SGI-110 is a dinucleotide antimetabolite of a decitabine linked via phosphodiester bond to a guanosine, with potential antineoplastic activity. Following metabolic activation by phosphorylation and incorporation into DNA, SGI-110 inhibits DNA methyltransferase, thereby causing genome-wide and non-specific hypomethylation and inducing cell cycle arrest at S-phase. This agent is resistant to cytidine deaminase, hence may result in gradual release of decitabine both extra- and intracellularly, leading to more prolonged exposures to decitabine. Uses: Antineoplastic agents. Synonyms: Guadecitabine; SGI 110; SGI110; 2'-deoxy-5-azacytidylyl-(3'->5')-2'-deoxyguanosine; (2R,3S,5R)-5-(4-amino-2-oxo-1,3,5-triazin-1(2H)-yl)-2-(hydroxymethyl)tetrahydrofuran-3-yl (((2R,3S,5R)-5-(2-amino-6-oxo-3,6-dihydro-9H-purin-9-yl)-3-hydroxytetrahydrofuran-2-yl)methyl) hydrogen phosphate. Grades: ≥95%. CAS No. 929901-49-5. Molecular formula: C18H24N9O10P. Mole weight: 557.41.
(S)-Tetrahydrofuran-3-ol
(S)-tetrahydrofuran-3-ol is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: (+)-3-Hydroxytetrahydrofuran. CAS No. 86087-23-2. Pack Sizes: 25 g. Product ID: HY-76476.