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| Product | Description | |
|---|---|---|
| (S)-(+)-Niguldipine hydrochloride | (S)-(+)-Niguldipine hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 113145-69-0. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. |  Worldwide |
| (S)-(+)-Niguldipine hydrochloride | (S)-(+)-Niguldipine hydrochloride, the more active enantiomer of Niguldipine hydrochloride, acts as a potent, selective α1A-adrenoceptor antagonist (Ki = 0.16 nM), and also is a L-type Ca2+ channel blocker. Uses: Antihypertensive agents. Synonyms: 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, 3-[3-(4,4-diphenyl-1-piperidinyl)propyl] 5-methyl ester, hydrochloride (1:1), (4S)-; 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, 3-(4,4-diphenyl-1-piperidinyl)propyl methyl ester, monohydrochloride, (4S)-; 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, 3-(4,4-diphenyl-1-piperidinyl)propyl methyl ester, monohydrochloride, (S)-; (+)-Niguldipine hydrochloride; (S)-Niguldipine hydrochloride; B 8509-034; BY 934; Niguldipine hydrochloride. Grades: ≥95%. CAS No. 113145-69-0. Molecular formula: C36H39N3O6.HCl. Mole weight: 646.18. |  |
| (+)-Niguldipine hydrochloride | (+)-Niguldipine hydrochloride is an antagonist for calcium channel. (+)-Niguldipine hydrochloride produces vasodilation by blocking calcium channels and reducing the transmembrane influx of calcium ions. (+)-Niguldipine hydrochloride inhibits U-46619 (HY-108566)-induced coronary vasoconstriction in guinea pig Langendorff heart with pID 50 of 11.37, binds to calcium channel on guinea pig skeletal muscle membrane with K i of 9.75, and lowers the blood pressure in spontaneously hypertensive rat with pED 30 of 7.1. (+)-Niguldipine hydrochloride ameliorates cardiovascular diseases such as hypertension, angina pectoris and arrhythmias [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (S)-Niguldipine hydrochloride. CAS No. 113145-69-0. Pack Sizes: 1 mg; 5 mg. Product ID: HY-101390. |  |
| (R)-(-)-Niguldipine hydrochloride | (R)-(-)-Niguldipine hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 113145-70-3. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| (R)-(-)-Niguldipine Hydrochloride | (R)-(-)-Niguldipine Hydrochloride, the less active enantiomer of Niguldipine Hydrochloride, is an L-type calcium channel protein inhibitor and α1A-AR (α1A-adrenoceptor) antagonist. Synonyms: 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, 3-(4,4-diphenyl-1-piperidinyl)propyl methyl ester, monohydrochloride, (4R)-; 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, 3-(4,4-diphenyl-1-piperidinyl)propyl methyl ester, monohydrochloride, (R)-; (-)-Niguldipine hydrochloride; (R)-Niguldipine hydrochloride; B 8509-035; B 859-35; BY 935; Dexniguldipine hydrochloride. Grades: ≥95%. CAS No. 113145-70-3. Molecular formula: C36H39N3O6.HCl. Mole weight: 646.18. | |
| Niguldipine hydrochloride | Cas No. 119934-51-9. | |
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