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(S)-AMPA. Group: Biochemicals. Alternative Names: (S)-α-Amino-3-hydroxy-5-methylisoxazole-4-propionic Acid; L-AMPA. Grades: Highly Purified. CAS No. 83643-88-3. Pack Sizes: 5mg. Molecular Formula: C7H10N2O4, Molecular Weight: 186.17. US Biological Life Sciences.
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(S)-AMPA
(S)-AMPA is an active enantiomer of AMPA, which has been found to be a definitive agonist of the AMPA glutamatergic ionotropic receptor. Synonyms: (S)-α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid. Grades: ≥99% by HPLC. CAS No. 83643-88-3. Molecular formula: C7H10N2O4. Mole weight: 186.17.
(S)-AMPA
(S)-AMPA (L-AMPA), an active S-enantiomer of AMPA, is a potent and selective AMPA receptor agonist [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: L-AMPA. CAS No. 83643-88-3. Pack Sizes: 5 mg; 10 mg. Product ID: HY-100815A.
Anti-phospho-AMPA Receptor, GluR1 Subunit (pSer831) antibody produced in rabbit
A caged version of (S)-AMPA. (S)-AMPA is an AMPA receptor agonist. Synonyms: (N)-1-(2-Nitrophenyl)ethylcarboxy-(S)-α-1-(2-nitrophenyl)ethylcarboxyamino-3-hydroxy-5-methyl-4-isoxazolepropionic acid. Grades: ≥98% by HPLC. CAS No. 1257323-84-4. Molecular formula: C16H17N3O8. Mole weight: 379.32.
NPEC-caged-(S)-AMPA
NPEC-caged-(S)-AMPA. Group: Biochemicals. Grades: Purified. CAS No. 1257323-84-4. Pack Sizes: 10mg. US Biological Life Sciences.
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(Rs)-ampa
(Rs)-ampa. Uses: Designed for use in research and industrial production. Additional or Alternative Names: (R,S)-2-AMINO-3-(3-HYDROXY-5-METHYL-4-ISOXAZOLYL)PROPIONIC ACID;(RS)-AMPA;(R,S)-A-AMINO-3-HYDROXY-5-METHYL-4-ISOXAZOLEPROPIONIC ACID;(RS)-ALFA-AMINO-3-HYDROXY-5-METHYL-4-ISOXAZOLEPROPIONIC ACID;(RS)-ALPHA-AMINO-3-HYDROXY-5-METHYL-4-ISOXAZOLEPROPIONIC ACID;2-AMINO-3-(3-HYDROXY-5-METHYLISOXAZOL-4-YL)PROPANOIC ACID;(+/-)-ALPHA-AMINO-3-HYDROXY-5-METHYL-4-ISOXAZOLEPROPIONIC ACID;(+/-)-ALPHA-AMINO-3-HYDROXY-5-METHYLISOXAZOLE-4-PROPIONIC ACID HYDRATE. Product Category: Heterocyclic Organic Compound. Appearance: solid. CAS No. 74341-63-2. Molecular formula: C7H10N2O4. Mole weight: 186.17. Product ID: ACM74341632. Alfa Chemistry ISO 9001:2015 Certified. Categories: R. Sampanthan.
(R,S)-AMPA
AMPA is the defining agonist for the AMPA subgroup of ionotropic glutamate receptors, which mediate excitatory neurotransmission. Synonyms: α-amino-3-hydroxy-5-methyl-4-Isoxazolepropionic Acid; 2-amino-3-(5-methyl-3-oxo-1,2-oxazol-4-yl)propanoic acid. Grades: ≥99%. CAS No. 77521-29-0. Molecular formula: C7H10N2O4. Mole weight: 186.2.
(RS)-AMPA
(RS)-AMPA. Group: Biochemicals. Grades: Purified. CAS No. 74341-63-2. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
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(RS)-AMPA
(RS)-AMPA has been found to be a definitive agonist of the AMPA glutamatergic ionotropic receptor. Uses: Excitatory amino acid agonists. Synonyms: (RS)-α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid. Grades: ≥99% by HPLC. CAS No. 74341-63-2. Molecular formula: C7H10N2O4. Mole weight: 186.17.
(RS)-AMPA hydrobromide
(RS)-AMPA hydrobromide. Group: Biochemicals. Grades: Purified. CAS No. 171259-81-7. Pack Sizes: 1mg, 10mg, 50mg. US Biological Life Sciences.
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(RS)-AMPA hydrobromide
The hydrobromide salt form of (RS)-AMPA, which has been found to be an agonist of the excitatory neurotransmitter L-glutamic Acid. Synonyms: (RS)-α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid hydrobromide. Grades: ≥99% by HPLC. CAS No. 171259-81-7. Molecular formula: C7H10N2O4.HBr. Mole weight: 267.08.
4-Isoxazolepropanoicacid,a-amino-2,3-dihydro-5-methyl-3-oxo-. Uses: Designed for use in research and industrial production. Additional or Alternative Names: (RS)-AMPA;(R,S)-A-AMINO-3-HYDROXY-5-METHYL-4-ISOXAZOLEPROPIONIC ACID;(RS)-ALPHA-AMINO-3-HYDROXY-5-METHYL-4-ISOXAZOLEPROPIONIC ACID;(RS)-ALFA-AMINO-3-HYDROXY-5-METHYL-4-ISOXAZOLEPROPIONIC ACID;(R,S)-2-AMINO-3-(3-HYDROXY-5-METHYL-4-ISOXAZOLYL)PROPIONIC ACI. Product Category: Heterocyclic Organic Compound. Appearance: White-to-Off White Powder. CAS No. 77521-29-0. Molecular formula: C7H10N2O4. Mole weight: 186.17. Purity: >99 %. IUPACName: (2S)-2-amino-3-(5-methyl-3-oxo-1,2-oxazol-4-yl)propanoic acid. Canonical SMILES: CC1=C(C(=O)NO1)CC(C(=O)O)N. Density: 1.386 g/cm³. Product ID: ACM77521290. Alfa Chemistry ISO 9001:2015 Certified.
5'-nucleotidase
Wide specificity for 5'-nucleotides. Group: Enzymes. Synonyms: uridine 5'-nucleotidase; 5'-adenylic phosphatase; adenosine 5'-phosphatase; AMP phosphatase; adenosine monophosphatase; 5'-mononucleotidase; AMPase; UMPase; snake venom 5'-nucleotidase; thimidine monophosphate nucleotidase; 5'-AMPase; 5'-AMP nucleotidase; AMP phosphohydrolase; IMP 5'-nucleotidase. Enzyme Commission Number: EC 3.1.3.5. CAS No. 9027-73-0. AMPase. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3654; 5'-nucleotidase; EC 3.1.3.5; 9027-73-0; uridine 5'-nucleotidase; 5'-adenylic phosphatase; adenosine 5'-phosphatase; AMP phosphatase; adenosine monophosphatase; 5'-mononucleotidase; AMPase; UMPase; snake venom 5'-nucleotidase; thimidine monophosphate nucleotidase; 5'-AMPase; 5'-AMP nucleotidase; AMP phosphohydrolase; IMP 5'-nucleotidase. Cat No: EXWM-3654.
5'-Nucleotidase from Human, Recombinant
5'-nucleotidase is an extracellular enzyme that converts nucleoside-5'-monophosphates to nucleosides with a substrate preference of AMP. Native 5'-nucleotidase is a GPI-anchored protein whose exporession is upregulated by hypoxia. 5'-nucleotidase has many functions in vivo including the generation of extracellular adenosine. 5'-Nucleotidase has various clinical significances. It is a key molecule in the regulation of cancer cells proliferation, migration and invasion in vitro tumor angiogenesis, and tumor immune escape in vivo. Due to this important role, the enzyme is a potential target for cancer research.1 It is also involved in salvage of extracellular nucleotides and...Enzyme Commission Number: EC 3.1.3.5. CAS No. 9027-73-0. Purity: >90% (SDS-PAGE). AMPase. Mole weight: ~61 kDa by SDS-PAGE (reducing). Activity: >15 U/mg. Storage: Store at -70°C. Form: Supplied as a solution containing Tris, NaCl, CaCl2, and 20% glycerol. Source: CHO cells. Species: Human. uridine 5'-nucleotidase; 5'-adenylic phosphatase; adenosine 5'-phosphatase; AMP phosphatase; adenosine monophosphatase; 5'-mononucleotidase; AMPase; UMPase; snake venom 5'-nucleotidase; thimidine monophosphate nucleotidase; 5'-AMPase; 5'-AMP nucleotidase; AMP phosphohydrolase; IMP 5'-nucleotidase; EC 3.1.3.5; CD73; NT5E; ecto-5'-nucleotidase. Pack: vial of 6-12 μg. Cat No: NATE-0795.
5'-Nucleotidase from Microorganism
5'-nucleotidase is an enzyme with system name 5'-ribonucleotide phosphohydrolase. This enzyme catalyses the following chemical reaction:a 5'-ribonucleotide + H2O? a ribonucleoside + phosphate. This enzyme has a wide specificity for 5'-nucleotides. Group: Enzymes. Synonyms: uridine 5'-nucleotidase; 5'-adenylic phosphatase; adenosine 5'-phosphatase; AMP phosphatase; adenosine monophosphatase; 5'-mononucleotidase; AMPase; UMPase; snake venom 5'-nucleotidase; thimidine monophosphate nucleotidase; 5'-AMPase; 5'-AMP nucleotidase; AMP phosphohydrolase; IMP 5'-nucleotidase; EC 3.1.3.5. Enzyme Commission Number: EC 3.1.3.5. CAS No. 9027-73-0. Activity: >50U/mg protein. Storage: Store at -20°C. Form: White amorphous powder. Source: Microorganism. uridine 5'-nucleotidase; 5'-adenylic phosphatase; adenosine 5'-phosphatase; AMP phosphatase; adenosine monophosphatase; 5'-mononucleotidase; AMPase; UMPase; snake venom 5'-nucleotidase; thimidine monophosphate nucleotidase; 5'-AMPase; 5'-AMP nucleotidase; AMP phosphohydrolase; IMP 5'-nucleotidase; EC 3.1.3.5; 5'NT. Cat No: NATE-1717.
Cytosolic 5'-nucleotidase II from Huamn, Recombinant
E.coli. Applications: Human cytosolic imp/gmp specific 5'-nucleotidase/phosphotransferase ii (cn-II) is a pure and active protein of 65kda cloned by rt-pcr amplification of mrna extracted from human hepatoma cells and expressed in e.coli. the sequence of the cloned nt5c2 gene (genbank accession number p49902) was confirmed by dna sequencing (100% identity). Group: Enzymes. Synonyms: uridine 5'-nucleotidase; 5'-adenylic phosphatase; adenosine 5'-phosphatase; AMP phosphatase; adenosine monophosphatase; 5'-mononucleotidase; AMPase; UMPase; snake venom 5'-nucleotidase; thimidine monophosphate nucleotidase; 5'-AMPase; 5'-AMP nucleotidase; AMP phosphohydrolase; IMP 5'-nucleotidase; EC 3.. Enzyme Commission Number: EC 3.1.3.5. CAS No. 9027-73-0. AMPase. Mole weight: 65kDa. Activity: ≥ 0.150 unit/mg protein. Storage: -20 °C in a solution containing 50 mM Tris-HCl, pH 7.6, 2 mM β-mercaptoethanol, 50% glycerol. Source: Human. Species: cN-II. uridine 5'-nucleotidase; 5'-adenylic phosphatase; adenosine 5'-phosphatase; AMP phosphatase; adenosine monophosphatase; 5'-mononucleotidase; AMPase; UMPase; snake venom 5'-nucleotidase; thimidine monophosphate nucleotidase; 5'-AMPase; 5'-AMP nucleotidase; AMP phosphohydrolase; IMP 5'-nucleotidase; EC 3.1.3.5; CD73; NT5E; ecto-5'-nucleotidase. Pack: stable lyophilized form. Cat No: NATE-1742.
(R)-3-(Fmoc-amino)-2-methylpropionic acid. Group: Biochemicals. Alternative Names: Fmoc-(R)-ampa-OH. Grades: Highly Purified. CAS No. 211682-15-4. Pack Sizes: 25mg, 50mg, 100mg, 250mg, 500mg. US Biological Life Sciences.
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(R)-AMPA
(R)-AMPA. Group: Biochemicals. Grades: Purified. CAS No. 83654-13-1. Pack Sizes: 10mg. US Biological Life Sciences.
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(R)-AMPA
(R)-AMPA is an inactive enantiomer of AMPA, which has been found to be a definitive agonist of the AMPA glutamatergic ionotropic receptor. Synonyms: (R)-α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid. Grades: ≥99% by HPLC. CAS No. 83654-13-1. Molecular formula: C7H10N2O4. Mole weight: 186.17.
A selective inhibitor of [3H]-AMPA binding in rat brain membranes. AMOA shows little affinity for [3H]-kainate binding sites or other sites on. Group: Biochemicals. Alternative Names: AMOA. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences.
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S 18986
S 18986 is a positive allosteric modulator of AMPA receptors that enhances (S)-AMPA-mediated noradrenaline release in rat hippocampal and frontal cortex slices. S 18986 exhibits neuroprotective and cognitive-enhancing properties in rodent behavioral models. Synonyms: S18986; S-18986; S 18986; S18986-1; S-18986-1; S 18986-1. (3aS)-2,3,3a,4-Tetrahydro-1H-pyrrolo[2,1-c][1,2,4]benzothiadiazine-5,5-dioxide. Grades: ≥98% by HPLC. CAS No. 175340-20-2. Molecular formula: C10H12N2O2S. Mole weight: 224.28.
ZK200775
Competitive AMPA/kainate antagonist. In rat cortical membranes, displays high affinity for [3H]-AMPA (Ki = 120 nM) and [3H]-CNQX (Ki = 32 nM) binding sites and low affinity for kainate and NMDA channel-associated binding sites (IC50 values range from 2.5 to 11 μM). Inhibits currents induced by AMPA, kainate and NMDA with IC50 values of 21 nM, 27 nM, and > 1 μM respectively. Displays anxiolytic, anticonvulsant and muscle relaxant activity in vivo. Synonyms: Fanapanel; MPQX; ZK-200775; ZK 200775; ZK200775. Grades: >98%. CAS No. 161605-73-8. Molecular formula: C14H15F3N3O6P. Mole weight: 409.25.
1-BCP
1-BCP is a centrally active selective potentiator of AMPA-mediated responses. Synonyms: Piperonylic acid piperidide; 1-(1,3-Benzodioxol-5-ylcarbonyl)piperidine; Piperidine, 1-(1,3-benzodioxol-5-ylcarbonyl)-; benzo[d][1,3]dioxol-5-yl(piperidin-1-yl)methanone; 1,3-Benzodioxol-5-yl(1-piperidinyl)methanone; 1,3-Benzodioxol-5-yl-1-piperidinylmethanone. Grades: ≥99% by HPLC. CAS No. 34023-62-6. Molecular formula: C13H15NO3. Mole weight: 233.27.
1-BCP
A centrally active selective potentiator of AMPA-mediated responses. Facilitates memory retention in rats. Group: Biochemicals. Grades: Highly Purified. CAS No. 34023-62-6. Pack Sizes: 10mg, 50mg. Molecular Formula: C13H15NO3. US Biological Life Sciences.
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1-N-Cbz-hydroxymethyl-piperidine
1-N-Cbz-hydroxymethyl-piperidine is an intermediate used in the synthesis of benzoyl oxyethyl piperidinyl methyl amine as fluorescent antagonists for human 5-HT4 receptors. It is also used to prepare diaminobutane derivatives as potent Ca2+-Permeable AMPA receptor antagonists. Group: Biochemicals. Grades: Highly Purified. CAS No. 122860-33-7. Pack Sizes: 1g, 5g. Molecular Formula: C14H19NO3, Molecular Weight: 249.31. US Biological Life Sciences.
A non-specific antagonist of NMDA, AMPA and kainate ionotropic receptors and a partial agonist for NMDA receptors. Used in blocking general excitatory synaptic transmissions. Group: Biochemicals. Grades: Highly Purified. CAS No. 46026-75-9. Pack Sizes: 50mg. US Biological Life Sciences.
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2,3-Dihydro-1-oxo-1h-indene-4-carbonitrile
2,3-Dihydro-1-oxo-1h-indene-4-carbonitrile is a reagent in the preparation and anticonvulsant activity of imidazoindenopyrazinon e carboxylic acid derivatives as AMPA antagonists. Group: Biochemicals. Grades: Highly Purified. CAS No. 60899-34-5. Pack Sizes: 25mg, 50mg. Molecular Formula: C10H7NO, Molecular Weight: 157.169999999999. US Biological Life Sciences.
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2-Acetamido-2-deoxy-3-O-(b-D-gluco-4-enepyranosyl uronic acid)-6-sulfo-D-galactopyranose disodium salt
2-Acetamido-2-deoxy-3-O-(b-D-gluco-4-enepyranosyl uronic acid)-6-sulfo-D-galactopyranose disodium salt, commonly known as AMPAGUS, is a multifaceted pharmaceutical entity meticulously designed to study a wide spectrum of inflammatory ailments plaguing humanity, including the formidable rheumatoid arthritis and the insidious Crohn's disease. With its remarkable intervention abilities, AMPAGUS efficaciously regulates and subdues vital enzymatic cascades orchestrating the arduous inflammatory response. Molecular formula: C14H19NO14S.2Na. Mole weight: 503.34.
2-Amino-4-trifluoromethylbenzoic Acid Methyl Ester is an intermediate used to prepare quinazolinedione sulfonamides as competitive AMPA receptor antagonists. It is also used in the synthesis of (arylamino) pyrimidobenzazepinones and pyrimidobenzazepinethi ones as inhibitors of polo-like kinase 1 and potential antitumor agents. Group: Biochemicals. Grades: Highly Purified. CAS No. 61500-87-6. Pack Sizes: 1g, 5g. Molecular Formula: C9H8F3NO2, Molecular Weight: 219.16. US Biological Life Sciences.
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2-Amino-5-chloro Benzene sulfonamide
2-Amino-5-chloro Benzene sulfonamide is a metabolite of IDRA-21 (I232500), which inhibits AMPA receptor desensitization and enhances cognition by a related mechanism. IDRA-21 is more able to cross the blood-brain barrier than Cyclothiazide (C988960). Group: Biochemicals. Grades: Highly Purified. CAS No. 5790-69-2. Pack Sizes: 500mg, 2.5g. Molecular Formula: C6H7ClN2O2S, Molecular Weight: 206.65. US Biological Life Sciences.
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2-Bromo-6-fluoroaniline
Used for preparation of cycloalkylated benzothiadiazine derivatives and their use as AMPA receptor modulators. Group: Biochemicals. Alternative Names: 2-Bromo-6-fluorobenzenamine. Grades: Highly Purified. CAS No. 65896-11-9. Pack Sizes: 5g. US Biological Life Sciences.
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2-MPPA
2-MPPA is a selective glutamate carboxypeptidase II (GCP II) inhibitor (IC50 = 90 nM), which is selective for GCP II over NMDA, kainate and AMPA glutamate receptors and MMP-1, -2, -3, -7, -9, ACE and NEP metalloproteases. 2-MPPA can be used in the treatment of neurological disorders associated with excessive activation of glutamatergic systems. Attenuates glutamate transmission resulting in the relief of neuropathic pain. This compound has neuroprotective properties. Synonyms: 2-(3-Mercaptopropyl)pentanedioic acid; 2-MPPA; 2 MPPA; 2MPPA. CAS No. 254737-29-6. Molecular formula: C8H14O4S. Mole weight: 206.26.
A potent agonist highly selective for kainate receptors over AMPA receptors (EC50 = 0.06-0.38uM and 132-453uM for kainate and AMPA receptors, respectively). Useful for distinguishing the functional roles played by kainate and AMPA receptors in neurotransmissions. Group: Biochemicals. Grades: Highly Purified. CAS No. 31137-74-3. Pack Sizes: 1mg. Molecular Formula: C?H??NO?. US Biological Life Sciences.
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6-Cyano-7-nitroquinoxaline-2,3-dione (CNQX)
A potent, competitive kainate/quisqualate (non-NMDA) receptor antagonist. IC50 of tritiated ligands to rat cortical membranes by CNQX: AMPA, Kainate and CPP are 0.3mM, 1.5mM, and 25mM, respectively. Group: Biochemicals. Alternative Names: CNQX. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
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6-Nitro-7-sulfamoylbenzo [f]quinoxaline-2, 3-dione, Disodium Salt (NBQX, Disodium Salt)
A potent and discriminating antagonist for AMPA binding sites. Group: Biochemicals. Alternative Names: NBQX, Disodium Salt. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences.
A potent and discriminating antagonist for AMPA binding sites. Group: Biochemicals. Alternative Names: NBQX. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences.
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807-Glyphosate and AMPA-Grain flour
807-Glyphosate and AMPA-Grain flour. Uses: For analytical and research use. Group: Food & beverage proficiency testing. Catalog: APS005147. Format: 25g barley flour.
Aminomethanephosphonic Acid
Atmosphere: Group: Biochemicals. Alternative Names: P- (Aminomethyl) phosphonic Acid; AMPA; AMPA; Aminomethanephosphonic Acid; Amino methyl enephosphonic Acid; NSC 30076; Nalco 3919; Phosphaglycine. Grades: Highly Purified. CAS No. 1066-51-9. Pack Sizes: 100mg, 250mg, 500mg, 1g, 5g. US Biological Life Sciences.
A potent, selective and systemically active positive allosteric modulator for mGlu7 receptor (EC50 = 64-290nM). One of the most frequently used agent for assessing the functional roles of mGlu7 receptors in a variety of brain functions (i.e. sleep pattern, learning and memory, and locomotion) and disorders (i.e. depression, anxiety, and Parkinsons disease). Induces internalization of mGlu7 receptors. Also acts onnMDA, AMPA, 5-HT receptors and norepinephrine transporter. Group: Biochemicals. Grades: Highly Purified. CAS No. 97075-46-2. Pack Sizes: 10mg. US Biological Life Sciences.
A bisalykylsulfonamide that acts as a positive, allosteric modulator against AMPA receptors (EC50 = 45nM and 63nM for GluA2i and GluA2o, respectively) in a HEK 293 calcium FLIPR assay. At 10uM, it robustly modulates receptor desensitization of both the flip (GluA2i) and flop (GluA2o) isoforms of GluA2 receptors in transfected HEK 293 cells with higher potency and efficacy than two other distinct AMPA modulators, cyclothiazide and CX614. Using a ligand bound crystal structure, it is shown to bind to the dimer interface of the extracellular ligand-binding domain of AMPA receptors, a region that partially overlaps with binding pockets for cyclothiazide and CX614. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg. Molecular Formula: C??H??N?O?S?, Molecular Weight: 376.5. US Biological Life Sciences.
AMPA/kainate antagonist-1 is a non-competitive AMPA/kainate antagonist. Synonyms: (r)-(+)-8-methyl-5-(3-methyl-4-nitrophenyl)-8,9-dihydro-7h-1,3-dioxolo[4,5-h][2,3]benzodiazepine. Grades: 98%. CAS No. 732277-05-3. Molecular formula: C18H17N3O4. Mole weight: 339.3.
AMPA/Kainate Antagonist-2
AMPA/kainate antagonist-2 is a non-competitive AMPA/kainate antagonist. Synonyms: AMPA/kainate antagonist-2; 923271-87-8; AMY40928BCP34146(+)-5-(4-amino-3-methylphenyl)-7-(2-thiazolyl)-8,9-dihydro-7H-1,3-dioxolo-[4,5-h][2,3]benzodiazepine. Grades: 98%. CAS No. 923271-87-8. Molecular formula: C20H18N4O2S. Mole weight: 378.4.
AMPA/kainate antagonist-3
AMPA/kainate antagonist-3 is a non-competitive AMPA/kainate antagonist. Grades: 98%. CAS No. 732278-52-3. Molecular formula: C21H21N5O2S. Mole weight: 407.5.
Ampalex
CX516 is a positive allosteric modulator at AMPA receptor that inhibits the deactivation of AMPA receptors. CX-516 is a nootropic and ampakine agent. Synonyms: CX-516; CX 516; CX516; BDP 12; BDP-12; BDP12; SPD-420; SPD420; brand name: Ampalex. Grades: >98%. CAS No. 154235-83-3. Molecular formula: C14H15N3O. Mole weight: 241.29.
Ampalex
It is one of a series of AMPA modulators. Group: Biochemicals. Alternative Names: 1-Piperidinyl-6-quinoxalinylmethanone; 1- (6-Quinoxalinylcarbonyl) piperidine; BDP 12; CX 516. Grades: Highly Purified. CAS No. 154235-83-3. Pack Sizes: 10mg. US Biological Life Sciences.
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Aniracetam
Aniracetam is a nootropics and neuroprotective drug. Synonyms: Aniracetam; Ampamet; Ro-13-5057; Ro 13 5057; Ro135057; Draganon; Sarpul. Grades: >98%. CAS No. 72432-10-1. Molecular formula: C12H13NO3. Mole weight: 219.24.
Aniracetam
Cognition enhancer related to Piracetam. Nootropic. Group: Biochemicals. Alternative Names: 1-(4-Methoxybenzoyl)-2-pyrrolidinone; Ampamet; Draganon; Ro 13-3057; Ro 13-5057; Ro 13-5057/001; Sarpul. Grades: Highly Purified. CAS No. 72432-10-1. Pack Sizes: 100mg. US Biological Life Sciences.
A positive allosteric modulator selective for AMPA receptors. Slows down AMPA receptor deactivation rate without altering the agonist potency. A leading candidate of ampakine nootropic for cognitive enhancement. Widely used in studies in a variety of brain functions (i.e. learn and memory, cognition) and disorders (depression, anxiety disorder, Alzheimer's disease, and aging). Group: Biochemicals. Grades: Highly Purified. CAS No. 72432-10-1. Pack Sizes: 50mg. US Biological Life Sciences.
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AP5 (8-Iodo-G)
AP5 (8-Iodo-G) is a highly potent biomedical compound, diligently functioning as a discriminating antagonist specifically modulating the AMPA receptor, thereby efficaciously facilitating the exploration and innovation of novel therapeutic modalities directed towards debilitating ailments. Synonyms: (AP5(8I-G)); P1-(5'-Adenosyl) P5-[5'-(8-iodo)-guanosyl] pentaphosphate, Sodium salt. Grades: ≥ 95% by HPLC. Molecular formula: C20H28IN10O23P5 (free acid). Mole weight: 1058.26 (free acid).
ATPA
ATPA is a potent and selective GluR5 kainate receptor agonist with Ki value of 4.3 nM. It is weakly active at AMPA receptors (GluR1-4), GluR7 and the kainate receptors KA-2. Synonyms: 4-Isoxazolepropanoic acid, α-amino-5-(1,1-dimethylethyl)-2,3-dihydro-3-oxo-; (RS)-2-Amino-3-(3-hydroxy-5-tert-butylisoxazol-4-yl)propanoic acid; α-Amino-5-(1,1-dimethylethyl)-2,3-dihydro-3-oxo-4-isoxazolepropanoic acid; 2-Amino-3-(5-(tert-butyl)-3-hydroxyisoxazol-4-yl)propanoic acid; 2-Amino-3-(5-tert-butyl-3-hydroxy-1,2-oxazol-4-yl)propanoic acid; 2-Amino-3-[3-hydroxy-5-tert-butylisoxazol-4-yl]propanoic acid; (R,S)-ATPA. Grades: ≥98% by HPLC. CAS No. 140158-50-5. Molecular formula: C10H16N2O4. Mole weight: 228.25.
A potent agonist highly selective for GluK1-containing subtype kainate receptors (EC50 = 0.33, 0.80, and 0.38uM for GluK1, GluK1/K2, and GluK1/K5, respectively) over GluK2-containing subtypes (EC50 = 106 and ?uM for GluK2/K5 and GluK2 respectively). Weakly interacts with AMPA receptors (EC50 = 7.6, 7.9 and 22uM for GluA4, GluA3, and GluA1 respectively). Has been used in assessing the functional roles of GluK1-containing subtype kainate receptors in synaptic transmission and plasticity. Group: Biochemicals. Grades: Highly Purified. CAS No. 140158-50-5. Pack Sizes: 1mg. Molecular Formula: C??H??N?O?. US Biological Life Sciences.
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BDP 37
It is one of a series of AMPA modulators. Group: Biochemicals. Alternative Names: 2,3,6a,7,8,9-Hexahydro-11H-1,4-dioxino[2,3-g]pyrrolo[2,1-b][1,3]benzoxazin-11-one; CX 614; LiD 37. Grades: Highly Purified. CAS No. 191744-13-5. Pack Sizes: 5mg. US Biological Life Sciences.
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CAY10608
The N-methyl-D-aspartate receptor (NMDA) is a glutamate receptor and ion channel protein found in nerve cells. The NMDA receptor is one of three types of ionotropic glutamate receptors. The other receptors are the AMPA and kainate receptors. NMDA is Ca2+ permeable ligand-gated channels of the central nervous system that are activated after binding of the co-agonists glutamate and glycine. CAY10608 is a propanolamine that potently, selectively, and non-competitively antagonizes the NR2B subunit of NMDA receptors with IC50 of 50 nM. Synonyms: CAY 10608; CAY-10608. Grades: ≥98%. CAS No. 457897-92-6. Molecular formula: C18H22Cl2N2O4S. Mole weight: 433.4.
CFM-2
CFM-2 is a potent and selective non-competitive AMPAR antagonist [1]. CFM-2 possesses anticonvulsant activity in various models of seizures [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 178616-26-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-12503.
CGP 78608 hydrochloride is a potent and selective NMDA antagonist with > 500-fold selectivity over kainate and AMPA receptors (IC50 = 2.7 and 3 μM, respectively). CGP 78608 exhibits an anticonvulsant effect in vivo following systemic administration. Synonyms: CGP78608 hydrochloride; CGP-78608 hydrochloride; [ (1S) -1-[[ (7-Bromo-1, 2, 3, 4-tetrahydro-2, 3-dioxo-5-quinoxalinyl) methyl]amino]ethyl]phosphonic acid hydrochloride; Phosphonic acid, P-[(1S)-1-[[(7-bromo-1,2,3,4-tetrahydro-2,3-dioxo-5-quinoxalinyl)methyl]amino]ethyl]-, hydrochloride (1:1); (S)-(1-(((7-Bromo-2,3-dioxo-1,2,3,4-tetrahydroquinoxalin-5-yl)methyl)amino)ethyl)phosphonic acid hydrochloride. Grades: ≥98% by HPLC. CAS No. 1135278-54-4. Molecular formula: C11H13BrN3O5P.HCl. Mole weight: 414.58.
cis-Piperidine-2,3-dicarboxylic acid
Cis-piperidine-2,3-dicarboxylic acid is a non-specific antagonist of NMDA, AMPA and kainate ionotropic receptors and a partial agonist for NMDA receptors. Cis-piperidine-2,3-dicarboxylic acid can be used in blocking general excitatory synaptic transmissions [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 46026-75-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-121964.
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