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| Product | Description | |
|---|---|---|
| 1-Methylpseudouridine | 1-Methylpseudouridine. Group: Biochemicals. Alternative Names: 1-Methyl-5-b-D-ribofuranosyl-2,4(1H,3H)-pyrimidinedione. Grades: Highly Purified. CAS No. 13860-38-3. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. US Biological Life Sciences. |  Worldwide |
| 1-MethylpseudoUridine | N1-methyl-pseudoUridine (1-Methylpseudouridine), a methylpseudoUridine, outperforms 5 mC and 5 mC/N1-methyl-pseudoUridine in translation. N1-methyl-pseudoUridine in mRNA enhances translation through eIF2α-dependent and independent mechanisms by increasing ribosome density. Synonyms: N1-Methylpseudouridine; 2,4(1H,3H)-Pyrimidinedione, 1-methyl-5-b-D-ribofuranosyl-; (-)-1-Methyl-5-(β-D-ribofuranosyl)-2,4(1H,3H)-pyrimidinedione; Antibiotic U-50228; U-50228; 1-N-Me-pseudouridine; (1S)-1,4-anhydro-1-(1-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)-D-ribitol; Uracil, 1-methyl-5-b-D-ribofuranosyl-. Grades: ≥95%. CAS No. 13860-38-3. Molecular formula: C10H14N2O6. Mole weight: 258.23. |  |
| 1-MethylpseudoUridine-5'-triphosphate | 1-MethylpseudoUridine-5'-triphosphate is a vital reagent in biomedical research. It is commonly used as a substrate to study RNA modifications and their role in gene expression regulation. This modified nucleotide analog allows for the analysis of enzymatic activities, RNA synthesis, and translation processes. It finds applications in the study of RNA splicing, RNA folding, and RNA-protein interactions, aiding in the understanding and potential treatment of various diseases. | |
| N1-MethylpseudoUridine-5'-Triphosphate | N1-MethylpseudoUridine-5'-Triphosphate is a modified NTP for incorporation into messenger RNAs (mRNA) using T7 RNA Polymerase. Incorporation of N1-methylpseudouridine can reduce the immunogenicity of the resulting mRNA. The sodium form N1-MethylpseudoUridine-5'-Triphosphate Sodium (B2706-358101) is in stock. Synonyms: 1-Methylpseudouridine-5'-Triphosphate; N1-Methylpseudo-UTP; 2,4(1H,3H)-Pyrimidinedione, 5-[5-O-[hydroxy[[hydroxy (phosphonooxy) phosphinyl]oxy]phosphinyl]-β -D-ribofuranosyl]-1-methyl-; 1-Methylpseudo-UTP. Grades: ≥95%. CAS No. 1428903-59-6. Molecular formula: C10H17N2O15P3. Mole weight: 498.17. | |
| N1-MethylpseudoUridine-5'-Triphosphate Lithium | N1-MethylpseudoUridine-5'-Triphosphate is a modified NTP for incorporation into messenger RNAs (mRNA) using T7 RNA Polymerase. Incorporation of N1-methylpseudouridine can reduce the immunogenicity of the resulting mRNA. The sodium form N1-MethylpseudoUridine-5'-Triphosphate Sodium (B2706-358101) is in stock. Synonyms: 1-Methylpseudouridine-5'-Triphosphate lithium salt; N1-Methylpseudo-UTP tetralithium salt; 2,4(1H,3H)-Pyrimidinedione, 5-[5-O-[hydroxy[[hydroxy (phosphonooxy) phosphinyl]oxy]phosphinyl]-β -D-ribofuranosyl]-1-methyl-, lithium salt; 1-Methylpseudo-UTP tetralithium salt. Grades: ≥90% by AX-HPLC. Molecular formula: C10H13Li4N2O15P3. Mole weight: 521.89. | |
| N1-MethylpseudoUridine-5'-Triphosphate Sodium | It is a modified NTP for incorporation into messenger RNAs (mRNA) using T7 RNA Polymerase. Incorporation of N1-methylpseudouridine can reduce the immunogenicity of the resulting mRNA. The product has passed the functionality test in transcription reaction. The solution is free of DNase and RNase contamination. Synonyms: 1-Methylpseudouridine-5'-Triphosphate sodium salt; N1-Methylpseudo-UTP sodium salt; 2,4(1H,3H)-Pyrimidinedione, 5-[5-O-[hydroxy[[hydroxy (phosphonooxy) phosphinyl]oxy]phosphinyl]-β -D-ribofuranosyl]-1-methyl-, sodium salt; 1-Methylpseudo-UTP sodium salt; 1-Methylpseudouridine-5'-Triphosphate; N1-Methylpseudo-UTP. Grades: 99%, 100mM sodium salt solution. Molecular formula: C10H17N2O15P3.xNa. Mole weight: 498.17 (free acid). | |
| 5,6-Dihydro-5-azathymidine | 5,6-Dihydro-5-azathymidine is produced by the strain of Streptomyces platensis var. clarensis (NRRL-8035). It has anti-gram-positive bacteria, negative bacteria and DNA virus activities. The strain also produces pseudouridine and 1-methylpseudouridine. Synonyms: 1-(2-Deoxypentofuranosyl)-4-hydroxy-5-methyl-5,6-dihydro-1,3,5-triazin-2(1H)-one. CAS No. 57350-36-4. Molecular formula: C9H15N3O5. Mole weight: 245.23. | |
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