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| Product | Description | |
|---|---|---|
| FK-506 (Fujimycin, Tacrolimus) | FK-506 is a potent immunosuppressant and in vitro T cell proliferation blocker. It has been shown to disrupt calcineurin (also known as CaN or phosphatase 2B)-mediated signal transduction in T lymphocytes. The compound interacts with its FK506-binding protein-12 (FKBP12). The resulting complex, in turn, interferes with calcineurin substrate interaction. Group: Biochemicals. Alternative Names: Advagraf; FR 900506; Fujimycin; L 679934; Prograf; Protopic; TacroBell; Tacrolimus; Tsukubaenolide. Grades: Highly Purified. CAS No. 104987-11-3. Pack Sizes: 50mg, 100mg, 500mg, 1g. Molecular Formula: C44H69NO12, Molecular Weight: 804.02. US Biological Life Sciences. |  Worldwide |
| FK-506 (Fujimycin, Tacrolimus)-13C,D2 | FK-506 (Fujimycin, Tacrolimus)-13C,D2. Group: Biochemicals. Alternative Names: FK-506-13C,D2. Grades: Highly Purified. CAS No. 104987-11-3forunlabelled. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Tacrolimus | FK-506 is a 23-membered macrolide lactone, it reduces peptidyl-prolyl isomerase activity by binding to the immunophilin FKBP12 (FK506 binding protein) creating a new complex. Uses: Drug. Synonyms: Prograf; Fujimycin; FK506; Protopy. Grades: >98%. CAS No. 104987-11-3. Molecular formula: C44H69NO12. Mole weight: 804.02. |  |
| Tacrolimus | Tacrolimus (FK506), a macrocyclic lactone, binds to FK506 binding protein (FKBP) to form a complex. Tacrolimus inhibits calcineurin phosphatase , which inhibits T-lymphocyte signal transduction and IL-2 transcription. Immunosuppressive properties [1]. Uses: Scientific research. Group: Natural products. Alternative Names: FK506; Fujimycin; FR900506. CAS No. 104987-11-3. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-13756. |  |
| Tacrolimus | Tacrolimus. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (3S, 4R, 5S, 8R, 9E, 12S, 14S, 15R, 16S, 18R, 19R, 26aS)-5, 19-dihydroxy-3-[(1E)-1-[(1R, 3R, 4R)-4-hydroxy-3-methoxycyclohexyl]prop-1-en-2-yl]-14, 16-dimethoxy-4, 10, 12, 18-tetramethyl-8-(prop-2-en-1-yl)-3, 4, 5, 6, 8, 11, 12, 13, 14, 15, 16, 17, 18, 19, 24, 25, 26, 26a-octadecahydro-7H-15, 19-epoxypyrido[2, 1-c][1, 4]oxaazacyclotricosine-1, 7, 20, 21(23H)-tetrone. CAS No. 104987-11-3. Molecular Formula: C44H69NO12. Mole Weight: 804.02. Catalog: APB104987113. |  |
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