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CYT387 Mesylate is an ATP-competitive inhibitor of JAK1/JAK2 with IC50 of 11 nM/18 nM, ~10-fold selectivity versus JAK3. Synonyms: Momelotinib Mesylate; CYT387 Mesylate; CYT 387 Mesylate; CYT-387 Mesylate. Grades: >98%. CAS No. 1056636-07-7. Molecular formula: C24H26N6O5S. Mole weight: 510.57.
Fasudil hydrochloride
Fasudil HCl, a 5-isoquinolinesulfonamide derivative, is a highly selective Rho-associated protein kinase inhibitor that might have a rate in romoting the recovery of neurological function, reducing clinical symptoms and the morbidity. Uses: Fasudil hcl, a 5-isoquinolinesulfonamide derivative, is a highly selective rho-associated protein kinase inhibitor that might have a rate in romoting the recovery of neurological function, reducing clinical symptoms and the morbidity. Synonyms: Fasudil HCl; Eril; Fasudil (Hydrochloride); Fasudil Monohydrochloride; AT-877; HA-1077; AT 877; HA 1077; AT877; HA1077. Grades: >98%. CAS No. 105628-07-7. Molecular formula: C14H18ClN3O2S. Mole weight: 327.83.
Fasudil hydrochloride
Other Alkaloids. Alternative Names: Eril. CAS No. 105628-07-7. Molecular formula: C14H18ClN3O2S. Mole weight: 327.83. Purity: 98%+. IUPACName: 5-(1, 4-Diazepan-1-ylsulfonyl)isoquinoline; hydrochloride. Canonical SMILES: C1CNCCN (C1)S (=O) (=O)C2=CC=CC3=C2C=CN=C3. Cl. Catalog: ACM105628077.
Fasudil Hydrochloride
Fasudil (HA-1077; AT877) Hydrochloride is a nonspecific RhoA/ROCK inhibitor and also has inhibitory effect on protein kinases, with an K i of 0.33 μM for ROCK1 , IC 50 s of 0.158 μM and 4.58 μM, 12.30 μM, 1.650 μM for ROCK2 and PKA , PKC , PKG , respectively. Fasudil Hydrochloride is also a potent Ca 2+ channel antagonist and vasodilator [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: HA-1077 Hydrochloride; AT-877 Hydrochloride. CAS No. 105628-07-7. Pack Sizes: 10 mM * 1 mL; 200 mg; 500 mg. Product ID: HY-10341.
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