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α-Lipoic Acid is a metabolic antioxidant that regulates NFκB signal transduction and can protect against oxidative injury. The exogenous compound is reduced intracellularly by enzymes. Its reduced form is involved in radical scavenging, recycling of other antioxidants, accelerating GSH synthesis, and regulating transcription factor activity, specifically NFkappaB. It also acts as a conenzyme that is required for the activity of pyruvate dehydrogenase and glycine decarboxylase, among other enzyme complexes. Studies show that it can prevent a decrease in the renal antioxidant defense system and prevent the increase of lipid peroxidation, platinum content and plasma creatinine concentrations. In other studies, lipoic acid decreased the phagocytosis of myelin by macrophages, acting as a non-specific scavenger of reactive oxygen species (ROS). Applications: A metabolic antioxidant that regulates nf-κb signal transduction. Group: Coenzymes. Synonyms: DL-Thioctic Acid; DL-6,8-Dithiooctanoic acid; 1,2-Dithiolane-3-valeric acid. CAS No. 1077-28-7. Purity: ≥95%. Mole weight: 206.32. Form: Solid. DL-Thioctic Acid; DL-6,8-Dithiooctanoic acid; 1,2-Dithiolane-3-valeric acid; α-Lipoic Acid; 1077-28-7. Cat No: COEC-041.
α-Lipoic Acid
α-Lipoic Acid (Thioctic acid) is an antioxidant, which is an essential cofactor of mitochondrial enzyme complexes. α-Lipoic Acid inhibits NF-κB -dependent HIV-1 LTR activation [1] [2] [3]. α-Lipoic Acid induces endoplasmic reticulum (ER) stress-mediated apoptosis in hepatoma cells [4]. α-Lipoic Acid can be used with CPUL1 (HY-151802) to construct the self-assembled nanoaggregate CPUL1-LA NA, which has improved antitumor efficacy than CPUL1 [5]. Uses: Scientific research. Group: Natural products. Alternative Names: Thioctic acid; (±)-α-Lipoic acid; DL-α-Lipoic acid. CAS No. 1077-28-7. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g. Product ID: HY-N0492.
Alpha Lipoic Acid
Alpha Lipoic Acid or ALA, is found in healthy foods such as spinach, chard, collard greens and broccoli, foods often deficient in standard American diets. It is an antioxidant that is found in every human cell. ALA at 5 % has been shown to reduce fine lines caused by sun damage. Uses: Anti-oxidants. Group: Skin Care Active Ingredients. INCI Name: Thioctic Acid. CAS Number: 1077-28-7.
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α-Lipoic Acid (Standard)
α-Lipoic Acid (Standard) is the analytical standard of α-Lipoic Acid. This product is intended for research and analytical applications. α-Lipoic Acid (Thioctic acid) is an antioxidant, which is an essential cofactor of mitochondrial enzyme complexes. α-Lipoic Acid inhibits NF-κB -dependent HIV-1 LTR activation [1] [2] [3]. α-Lipoic Acid induces endoplasmic reticulum (ER) stress-mediated apoptosis in hepatoma cells [4]. α-Lipoic Acid can be used with CPUL1 (HY-151802) to construct the self-assembled nanoaggregate CPUL1-LA NA, which has improved antitumor efficacy than CPUL1 [5]. Uses: Scientific research. Group: Natural products. Alternative Names: Thioctic acid (Standard); (±)-α-Lipoic acid (Standard); DL-α-Lipoic acid (Standard). CAS No. 1077-28-7. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0492R.
Alpha-lipoic Acid USP
Alpha-lipoic Acid USP. CAS No. 1077-28-7. Molecular formula: C8H14O2S2.
DL-alpha-Lipoic acid (DL Thioctic acid)
25g Pack Size. Group: Bioactive Small Molecules, Building Blocks, Chiral Compounds, Flavours and Fragrance Materials. Formula: C8H14O2S2. CAS No. 1077-28-7. Prepack ID 27534819-25g. Molecular Weight 206.33. See USA prepack pricing.
DL-alpha-Lipoic acid (DL Thioctic acid)
5g Pack Size. Group: Bioactive Small Molecules, Building Blocks, Chiral Compounds, Flavours and Fragrance Materials. Formula: C8H14O2S2. CAS No. 1077-28-7. Prepack ID 27534819-5g. Molecular Weight 206.33. See USA prepack pricing.
Dl-thioctic acid
A fat-metabolism stimulator. Group: Heterocyclic organic compound. Alternative Names: 5-(dithiolan-3-yl)pentanoic acid;6,8-Dithiooctanoic acid;1,2-Dithiolane-3-pentanoic acid;(±)-1,2-Dithiolane-3-pentanoic acid;DL-Thioctic acid. CAS No. 1077-28-7. Molecular formula: C8H14O2S2. Mole weight: 206.33. Appearance: Light yellow to yellow powder. Density: 1.218 g/cm³. ECNumber: 214-071-2. Catalog: ACM1077287.
DL-Thioctic acid
DL-Thioctic acid is a non-specific free radical scavenger and has anti-oxidant properties. It could be used as a fat-metabolism stimulator. Synonyms: Thioctic acid; alpha-Lipoic acid; (+-)-2-dithiolane-3-pentanoic acid; (+-)-2-dithiolane-3-valeric acid; (+/-)-2-dithiolane-3-pentanoic acid; 1,2-Dithiolane-3-pentanoic acid; 1,2-Dithiolane-3-pentanoic acid, (±)-; 1,2-Dithiolane-3-valeric acid, (±)-; (RS)-Lipoic acid; (RS)-α-Lipoic acid; (±)-Lipoic acid; (±)-Thioctic acid; (±)-α-Lipoic acid; 5-(1,2-Dithiolan-3-yl)pentanoic acid; 5-(1,2-Dithiolan-3-yl)valeric acid; 6,8-Thioctic acid; 6-Thioctic acid; DL-6,8-Thioctic acid; DL-6-Thioctic acid; DL-Lipoic acid; DL-α-Lipoic acid; Alipure; Biletan; Byodinoral-R; dl-α-Lipoic acid; Espa-lipon; Liposan; Lipothion; NSC 628502; NSC 90788; Octolipen; Oktolipen; Protogen A; Pyruvate oxidation factor; Thioctic acid; Thioctsan; Tioctidasi; Tioctidasi acetate replacing factor; α-(±)-Lipoic acid; α-lipon 300; α-Liponic acid. Grades: 98%. CAS No. 1077-28-7. Molecular formula: C8H14O2S2. Mole weight: 206.32.
?-Lipoic acid
?-Lipoic acid. CAS No: 1077-28-7
Sarchem Laboratories New Jersey NJ
Lipoic Acid (Thioctic Acid, Alpha Lipoic Acid)
Coenzyme in the oxidative decarboxylation reactions of glucose metabolism and the citric acid cycle. Although it is an essential growth factor for various micro-organisms. a-Lipoic acid, is a naturally occuring coenzyme containing a disulfide that has been used to treat polyneuropathies and hepatic disorders. a-Lipoic acid is a potent inhibitor of NFKB activation and HIV-1 tat driven gene expression. Group: Biochemicals. Alternative Names: (+/-)-1,2-Dithiolane-3-pentanoic Acid; (+/-)-1,2-Dithiolane-3-valeric Acid; (+/-)-Thioctic Acid; (RS)-α-Lipoic Acid; DL-Thioctic Acid; Liposan; Lipothion; NSC 628502; NSC 90788; Protogen A; Thioctsan; Tioctacid. Grades: Cell Culture Grade. CAS No. 1077-28-7. Pack Sizes: 10g, 25g, 100g, 500g. Molecular Formula: C8H14O2S2, Molecular Weight: 206.3. US Biological Life Sciences.
Worldwide
rac a-lipoic acid
rac a-lipoic acid. Group: Biochemicals. Alternative Names: (+/-)-1,2-Dithiolane-3-pentanoic acid; (+/-)-1,2-Dithiolane-3-valeric acid; (+/-)-Thioctic acid. Grades: Highly Purified. CAS No. 1077-28-7. Pack Sizes: 50g, 100g, 250g, 500g, 1kg. Molecular Formula: C8H14O2S2. US Biological Life Sciences.
Thioctic Acid EP Impurity B. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1077-28-7. Molecular Formula: C8H14O2S2. Mole Weight: 206.32. Catalog: APB1077287.
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