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Topotecan HCl. Group: Biochemicals. Alternative Names: (4S)-10-[ (Dimethylamino)methyl]-4-ethyl-4, 9-dihydroxy-1H-pyrano[3', 4', 6-7]indolizino[1, 2-b]quinoline-3, 14 (4H, 12H)-dione hydrochloride; NSC-609669; SKF-104864A. Grades: Highly Purified. CAS No. 119413-54-6. Pack Sizes: 25mg, 50mg, 100mg, 250mg, 500mg. Molecular Formula: C23H24ClN3O5. US Biological Life Sciences.
Worldwide
Topotecan hydrochloride
Topocecan is a semisynthetic derivative of camptothecin with antineoplastic activity. During the S phase of the cell cycle, topotecan selectively stabilizes topoisomerase I-DNA covalent complexes, inhibiting religation of topoisomerase I-mediated single-strand DNA breaks and producing potentially lethal double-strand DNA breaks when complexes are encountered by the DNA replication machinery. Camptothecin is a cytotoxic quinoline-based alkaloid extracted from the Asian tree Camptotheca acuminata. Uses: Topoisomerase i inhibitors. Synonyms: 1H-Pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione, 10-[(dimethylamino)methyl]-4-ethyl-4,9-dihydroxy-, hydrochloride (1:1), (4S)-; 1H-Pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione, 10-[(dimethylamino)methyl]-4-ethyl-4,9-dihydroxy-, monohydrochloride, (4S)-; 1H-Pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione, 10-[(dimethylamino)methyl]-4-ethyl-4,9-dihydroxy-, monohydrochloride, (S)-; (S)-10-[(Dimethylamino)methyl]-4-ethyl-4,9-dihydroxy-1H-pyrano[3',4':6,7]indolizino[l,2-b]quinoline-3,14(4H,12H)-dione monohydrochloride; Hycamtin; Nogitecan hydrochloride; NSC 609669; SKF 104864A; SKFS 104864A; Topotecan chlorohydrate; Xinze. Grade: >98%. CAS No. 119413-54-6. Molecular formula: C23H24ClN3O5. Mole weight: 457.91.
Topotecan hydrochloride
Topotecan hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 119413-54-6. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
Topotecan hydrochloride
Topotecan Hydrochloride (SKF 104864A Hydrochloride) is a Topoisomerase I inhibitor with potent antineoplastic activities. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 1,4-Di[4-(3-phenoxypropoxy)-2-butynyl]piperazine. Product Category: Inhibitors. Appearance: Light-yellow powder. CAS No. 119413-54-6. Molecular formula: C23H24ClN3O5. Mole weight: 457.91. Purity: 0.98. IUPACName: (19S)-8-[(dimethylamino)methyl]-19-ethyl-7,19-dihydroxy-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4(9),5,7,10,15(20)-heptaene-14,18-dione;hydrochloride. Canonical SMILES: CC[C@@]1(C2=C(COC1=O)C(=O)N3CC4=CC5=C(C=CC(=C5CN(C)C)O)N=C4C3=C2)O.Cl. Product ID: ACM119413546. Alfa Chemistry ISO 9001:2015 Certified.
Topotecan hydrochloride
Topotecan Hydrochloride (SKF 104864A Hydrochloride) is a Topoisomerase I inhibitor with potent antineoplastic activities. Uses: Scientific research. Group: Natural products. Alternative Names: SKF 104864A hydrochloride; NSC 609669 hydrochloride. CAS No. 119413-54-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13768A.