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| Product | Description | |
|---|---|---|
| Calphostin C | 0mg Pack Size. Group: Bioactive Small Molecules, Biochemicals, Research Organics & Inorganics. Formula: C44H38O14. CAS No. 121263-19-2. Prepack ID 33060444-0mg. Molecular Weight 790.76. See USA prepack pricing. |  |
| Calphostin C | Calphostin C is a highly selective PKC inhibitor ( IC 50 =0.05 μM) and tumor apoptosis inducer. Calphostin C competitively binds to PKC and inhibits PKC-mediated phosphorylation signal transduction. Calphostin C restores Na+/K+ ATPase activity in the sciatic nerve of diabetic mice and improves neuropathy. Calphostin C can be used in the study of anti-tumor and diabetic complications [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: UCN-1028C. CAS No. 121263-19-2. Pack Sizes: 100 μg. Product ID: HY-105416. |  |
| Calphostin C | Calphostin C is a protein kinase C inhibitor produced by cladosporium cladosporioides. Synonyms: UCN 1028 C, PKF 115-384. Grades: >95% by HPLC. CAS No. 121263-19-2. Molecular formula: C44H38O14. Mole weight: 790.76. |  |
| Calphostin C (Antibiotic UCN-1028 C, UCN 1028 C) | Calphostin C is a perylenequinione isolated from the fungus, Cladosporium cladosporioides. It is a potent and specific inhibitor of protein kinase C with inhibition being light dependent. Also shown to inhibit cell proliferation and induce apoptosis in vitro. Group: Biochemicals. Alternative Names: Antibiotic UCN-1028 C, UCN 1028 C. Grades: Highly Purified. CAS No. 121263-19-2. Pack Sizes: 100ug. US Biological Life Sciences. |  Worldwide |
| Calphostin C (UCN 1028C, PKF115-584, Cal-C) | Potent and highly specific cell permeable protein kinase C (PKC) inhibitor. The inhibition of PKC is light-dependent. PKA, PKG, DAG kinase, phospholipase D1 and D2, myosin light chain kinase and c-Src inhibitor. Anticancer compound. Inhibits cell proliferation and strongly induces apoptosis in vitro. Inducer of endoplasmic reticulum ER-stress. Shown to directly and potently block L-type Ca channels. Calphostin C specifically inhibits contraction-stimulated glucose transport but not insulin-stimulated glucose transport in skeletal muscle. Wnt/beta-catenin/lef-1 signaling inhibitor. beta-catenin/TCF antagonist. Inhibits Wnt-activated genes in a dose-dependent fashion. Source:Cladosporium cladosporioides sp. Group: Biochemicals. Grades: Highly Purified. CAS No. 121263-19-2. Pack Sizes: 100ug, 1mg. Molecular Formula: C44H38O14 , Molecular Weight: ~790.8. US Biological Life Sciences. | Worldwide |
| Carbonic acid,(1R)-2-[12-[(2R)-2-(benzoyloxy)propyl]-3,10-dihydro-4,9-dihydroxy-2,6,7,11-tetramethoxy-3,10-dioxo-1-perylenyl]-1-methylethyl4-hydroxyphenyl ester,stereoisomer | Heterocyclic Organic Compound. Alternative Names: Calphostin C; 1-[3, 10-dihydroxy-12-[2-(4-hydroxyphenoxy)carbonyloxypropyl]-2, 6, 7, 11-tetramethoxy-4, 9-dioxoperylen-1-yl]propan-2-yl benzoate. CAS No. 121263-19-2. Molecular formula: C44H38O14. Mole weight: 790.7641. Appearance: red to brown powder. Purity: >98 %. IUPACName: 1-[3, 10-dihydroxy-12-[2-(4-hydroxyphenoxy)carbonyloxypropyl]-2, 6, 7, 11-tetramethoxy-4, 9-dioxoperylen-1-yl]propan-2-yl benzoate. Canonical SMILES: CC (CC1=C (C (=C2C (=O)C=C (C3=C4C (=CC (=O)C5=C (C (=C (C (=C45)C1=C32)CC (C)OC (=O)OC6=CC=C (C=C6)O)OC)O)OC)OC)O)OC)OC (=O)C7=CC=CC=C7. Density: 1.48 g/cm³. Catalog: ACM121263192. |  |
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