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Fmoc-Cys(STmp)-OH Fmoc-Cys(STmp)-OH is a novel new tool for the regioselective synthesis of multiple disulfide bridged peptides by Fmoc SPPS. The STmp group is stable to piperidine but is extremely easy to remove by mild thiolysis. Albericio has reported removing four STmp groups on the solid phase with only three 5 minute treatments of 0.1 M N-methylmorpholine (NMM) in DMF containing 5% DTT. Uses: Peptide synthesis. Group: Amino acids. Alternative Names: Fmoc-Cys(STmp)-OH, N-α-Fmoc-S-2,4,6-trimethoxyphenylthio-L-cysteine. CAS No. 1403834-74-1. Molecular formula: C27H27NO7S2. Mole weight: 541.64. IUPACName: (2R)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-[(2,4,6-trimethoxyphenyl)disulfanyl]propanoic acid. Canonical SMILES: COC1=CC (=C (C (=C1)OC)SSCC (C (=O)O)NC (=O)OCC2C3=CC=CC=C3C4=CC=CC=C24)OC. Density: 1.4±0.1 g/cm3. Catalog: ACM1403834741. Alfa Chemistry.

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