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| Product | Description | |
|---|---|---|
| Deltarasin | Deltarasin. Group: Biochemicals. Grades: Purified. CAS No. 1440898-82-7. Pack Sizes: 10mg. US Biological Life Sciences. |  Worldwide |
| Deltarasin | Deltarasin inhibits the interaction of RAS with PDEδ with KD of 41 nM. Inhibition of PDEδ-KRAS interaction by Deltarasin suppresses proliferation of human pancreatic ductal adenocarcinoma cells that are dependent on oncogenic KRAS. Synonyms: Deltarasin; 1440898-61-2; CHEMBL3286929; 1-benzyl-2-[4-[(2S)-2-(2-phenylbenzimidazol-1-yl)-2-piperidin-4-ylethoxy]phenyl]benzimidazole; 1440898-82-7; SCHEMBL15474539; BCP20971; EX-A1042; BDBM50019865; MFCD26793865; NSC779408; s7224; AKOS030526539; CCG-270204; CS-1611; NSC-779408; NCGC00378602-10; AC-32917; HY-15747; MS-30649; SW219816-1; J-690178; (S)-1-benzyl-2-(4-(2-(2-phenyl-1H-benzo[d]imidazol-1-yl)-2-(piperidin-4-yl)ethoxy)phenyl)-1H-benzo[d]imidazole; 1-[(1S)-2-[4-(1-benzyl-1H-1,3-benzodiazol-2-yl)phenoxy]-1-(piperidin-4-yl)ethyl]-2-phenyl-1H-1,3-benzodiazole; 1-benzyl-2-{4-[(2S)-2-(2-phenyl-1H-1,3-benzodiazol-1-yl)-2-(piperidin-4-yl)ethoxy]phenyl}-1H-1,3-benzodiazole; O7T. Grades: >98%. CAS No. 1440898-61-2. Molecular formula: C40H37N5O. Mole weight: 603.75. |  |
| Deltarasin hydrochloride | Small molecule inhibitor of the KRAS-PDEδ interaction that impairs oncogenic KRAS signalling by altering its localization to endomembranes (in cell Kd value 41 nM for deltarasin binding to PDEδ). Deltarasin suppresses in vitro and in vivo MAPK signaling and proliferation of human pancreatic ductal adenocarcinoma (PDAC) cells that are dependent on oncogenic KRAS. Synonyms: Deltarasin hydrochloride. Grades: >98%. CAS No. 1440898-82-7. Molecular formula: C40H38ClN5O. Mole weight: 640.22. | |
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