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L-Methionine-DL-sulfoximine L-Methionine-DL-sulfoximine (MSX; MSO), a highly specific and irreversible inhibitor of Glutamine synthetase (GS), is also a potent convulsant which metabolically and morphologically primarily affects astroglia. L-Methionine-DL-sulfoximine has been employed to inhibit the Gln-dependent ammonia-stimulated neuronal toxicity in vitro, potentiating Gln deficit-dependent depression. L-Methionine-DL-sulfoximine tremendously increases the rate of release of fixed nitrogen in cyanobacteria. L-Methionine-DL-sulfoximine is a promising candidate for research in biofertilizers and convulsive seizures (CS)[1][2][3][4][5]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MSX; MSO. CAS No. 15985-39-4. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg; 1 g; 5 g. Product ID: HY-B1692. MedChemExpress MCE
L-Methionine [R,S]-Sulfoximine L-Methionine-(S,R)-sulfoximine is an inhibitor of glutamine synthetase and a sulfoximine derivative of L-methionine. Synonyms: L-Methionine Sulfoximine. CAS No. 15985-39-4. Molecular formula: C5H12N2O3S. Mole weight: 180.23. BOC Sciences 5
L-Methionine [R,S]-Sulfoximine Methionine sulfoximine inhibits both glutamine synthetase and g-glutamylcysteine synthetase. Working concentrations for inhibition of g-glutamylcysteine synthetase are 0.2-2.0mM (52% inhibition occured at 100mM).Methionine sulfoximine is also a toxic byproduct of nitrogen trichloride, a compound that was used to bleach unprocessed wheat flour prior to 1968. The compound has been investigated as a potential neurotoxin linked to diseases such as amyotrophic lateral sclerosis (ALS) and Parkinson’s disease. Group: Biochemicals. Alternative Names: L-S-[3-Amino-3-carboxypropyl]-S-methyl-[R,S]-sulfoximine; (2S) -2-Amino-4- (S-methylsulfonimidoyl) butanoic Acid. Grades: Highly Purified. CAS No. 15985-39-4. Pack Sizes: 100mg, 250mg, 500mg, 1g. Molecular Formula: C?H??N?O?S, Molecular Weight: 180.23. US Biological Life Sciences. USBiological 1
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