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2'-Deoxyuridine-5'-triphosphate sodium salt (dUTP Na)
2'-Deoxyuridine-5'-triphosphate trisodium salt (CAS# 102814-08-4) is a nucleotide and the sodium salt of dUTP, used as an analyte in biological assays. Group: Biochemicals. Alternative Names: 2'-deoxy-Uridine 5'-(tetrahydrogen triphosphate) trisodium salt; dUTP trisodium salt; dUTP sodium salt. Grades: Highly Purified. CAS No. 102814-08-4. Pack Sizes: 25mg, 100mg, 250mg, 1g. Molecular Formula: C?H??N?O??P?Na?, Molecular Weight: 534.09. US Biological Life Sciences.
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2'-Deoxyuridine-5'-triphosphate trisodium salt
dUTP is a deoxynucleoside triphosphate (dNTP) that acts as a substrate for several enzymes. It can be used in PCR and qPCR. Synonyms: Deoxyuridine triphosphate trisodium salt; deoxy-UTP trisodium salt; dUTP trisodium salt; 2'-deoxy-Uridine 5'-(tetrahydrogen triphosphate) trisodium salt. Grades: ≥99% by HPLC. CAS No. 102814-08-4. Molecular formula: C9H12N2O14P3·3Na. Mole weight: 534.09.
2'-Amino-2'-deoxyuridine-5'-triphosphate
2'-Amino-2'-deoxyuridine-5'-triphosphate, a pivotal constituent employed in the field of molecular biology, assumes the role of a vital substrate for DNA polymerase within the context of PCR amplifications. Such utilization affords the opportunity for the meticulous labeling and integration of modified nucleotides. Advantaged by its indispensability, this product facilitates genetic sequencing, fluorescent labeling, as well as manipulation of genes of utmost significance in the domains of drug discovery and disease diagnostics. Synonyms: 2'Amino-dUTP. Grades: ≥90% by AX-HPLC. CAS No. 61468-90-4. Molecular formula: C9H16N3O14P3. Mole weight: 483.16.
2'-Amino-2'-deoxyuridine-5'-triphosphate
2'-Amino-2'-deoxyuridine-5'-triphosphate. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1ug, 5ug, 10ug. US Biological Life Sciences.
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2'-Azido-2'-deoxyuridine-5'-triphosphate
2'-Azido-2'-deoxyuridine-5'-triphosphate. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1ug, 5ug, 10ug. US Biological Life Sciences.
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2'-Azido-2'-deoxyuridine-5'-triphosphate
2'-Azido-2'-deoxyuridine-5'-triphosphate is a critical reagent widely used in biomedical research, specifically in studies involving DNA labeling and DNA sequencing. It plays an essential role in the development and analysis of novel antiviral drugs. This nucleotide analogue is used to investigate viral replication mechanisms and identify potential drug targets against viral diseases, including HIV and hepatitis B. Synonyms: 2'-Azido-dUTP; 2'N3-UTP. Grades: ≥90% by AX-HPLC. CAS No. 106448-30-0. Molecular formula: C9H14N5O14P3. Mole weight: 509.15.
2'-Fluoro-2'-deoxyuridine-5'-triphosphate lithium salt
2'-Fluoro-2'-deoxyuridine-5'-triphosphate lithium salt. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 50mg, 100mg, 250mg, 500mg, 1g. US Biological Life Sciences.
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2'-Fluoro-2'-deoxyuridine-5'-triphosphate trisodium salt
2'-Fluoro-2'-deoxyuridine-5'-triphosphate trisodium salt, a nucleotide analog in biochemistry and molecular biology, stands out due to its versatility as a substrate for DNA Polymerases in DNA synthesis studies. Moreover, it shows promise as an anti-cancer agent in treating breast cancer and pancreatic cancer by hindering DNA replication. With this in mind, its relevance and significance linger in the scientific community and beyond. Synonyms: 2'-Deoxy-2'-fluorouridine 5'-(tetrahydrogen triphosphate) trisodium salt; 2'-Fluoro-dUTP trisodium salt. Grades: ≥97% by HPLC. Molecular formula: C9H11FN2Na3O14P3. Mole weight: 552.08.
2'-Deoxy-2'-fluorouridine-5'-triphosphate tetralithium salt
2'-Deoxy-2'-fluorouridine-5'-triphosphate tetralithium salt is a vital compound in biomedicine used for various research purposes. It serves as a nucleotide analog that incorporates into DNA during synthesis, aiding in the study of DNA replication, repair, and mutagenesis. This compound can also be utilized in the development of antiviral drugs targeting RNA viruses such as hepatitis C and HIV. Synonyms: 2'-Fluoro-2'-deoxyuridine-5'-triphosphate. Grades: 95%. Molecular formula: C9H11FN2O14P3Li4. Mole weight: 510.87 (free acid).
2'-Deoxyuridine 5'-triphosphate
2'-Deoxyuridine 5'-triphosphate, a nucleotide analog, is utilized in DNA synthesis and repair. The drug finds wide application in treating viral infections, most notably herpes and HIV. Administration of this drug leads to the termination of chain growth and subsequent inhibition of viral replication. It is a substrate for DNA polymerase and is incorporated during DNA chain elongation. Such incorporation plays a significant role in the fight against virally induced diseases. Synonyms: 2'-Deoxyuridine-5'-Triphosphoric Acid; Deoxyuridine triphosphate; deoxy-UTP; dUTP; Deoxyuridine-5'-Triphosphate; 2'-deoxyuridine 5'-(tetrahydrogen triphosphate); Uridine 5'-(tetrahydrogen triphosphate), 2'-deoxy-; ((2R,3S,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3-hydroxytetrahydrofuran-2-yl)methyl tetrahydrogen triphosphate. Grades: 95%. CAS No. 1173-82-6. Molecular formula: C9H15N2O14P3. Mole weight: 468.14.
2'-Fluoro-dUTP
2'-Fluoro-dUTP is a deoxyuridine analog. Synonyms: 2'-Fluoro-2'-deoxyuridine-5'-triphosphate; 2'F-dUTP; 2'-Deoxy-2'-fluorouridine-5'-triphosphate; Uridine 5'-(tetrahydrogen triphosphate), 2'-deoxy-2'-fluoro-; [[(2R,3R,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-4-fluoro-3-hydroxy-tetrahydrofuran-2-yl]methoxy-hydroxy-phosphoryl] phosphono hydrogen phosphate; 2'-Deoxy-2'-fluorouridine 5'-(tetrahydrogen triphosphate). Grades: ≥95% by HPLC. CAS No. 66840-02-6. Molecular formula: C9H14FN2O14P3. Mole weight: 486.13.
2'NH2-dUTP
2'NH2-dUTP is a revolutionary modified nucleotide, garnering exceptional significance in nucleic acid labeling and detection. This prodigious entity presents an amine group that procures unparalleled proficiency in facilitating the attachment of diverse fluorophores or alternative labels. Synonyms: 2'-Amino-2'-deoxyuridine-5'-triphosphate, Sodium salt; 2'-Amino-dUTP. Grades: ≥ 95% by HPLC. Molecular formula: C9H16N3O14P3 (free acid). Mole weight: 483.16 (free acid).
3'-Deoxyuridine-5'-triphosphate trisodium
3'-Deoxyuridine-5'-triphosphate trisodium is a nucleotide analogue that strongly and competitively inhibits the incorporations of UTP into RNA with a Ki value of 2.0 μM. Synonyms: 3'-dUTP trisodium. Grades: 99%. Molecular formula: C9H15N2Na3O14P3. Mole weight: 537.11.
5-AcOHg-dUTP
5-AcOHg-dUTP, a modified nucleotide with applications in both research and diagnostics, serves as a pivotal tool for incisive study of DNA replication and repair while also bearing immense potential in the development of advanced disease detection techniques, as a cancer and viral infection marker. Synonyms: 5-Mercuryacetat-2'-deoxyuridine-5'-triphosphate, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C11H17HgN2O16P3 (free acid). Mole weight: 726.77 (free acid).
5-Aminoallyl 2'-deoxyuridine 5'-triphosphate lithium salt
5-Aminoallyl 2'-deoxyuridine 5'-triphosphate lithium salt. Group: Biochemicals. Alternative Names: 5-Aminoallyl-2'-deoxyuridine-5'-triphosphate; 5-AA-dUTP.Li. Grades: Highly Purified. CAS No. 116840-18-7. Pack Sizes: 1mg, 2.5mg, 5mg. Molecular Formula: C12H20N3O14P3. US Biological Life Sciences.
Worldwide
5-Aminoallyl 2'-deoxyuridine 5'-triphosphate sodium salt
5-Aminoallyl 2'-deoxyuridine 5'-triphosphate sodium salt. Group: Biochemicals. Alternative Names: 5-(3-Aminoallyl)-2'-deoxyuridine-5'-triphosphate sodium salt. Grades: Highly Purified. CAS No. 116840-18-7,936327-10-5. Pack Sizes: 1mg, 2mg, 5mg. Molecular Formula: C12H20N3O14P3·xNa. US Biological Life Sciences.
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5-Bromo-dUTP
5-Bromo-dUTP is a substrate for reverse transcriptase. It is commonly used in tunel assay to detect apoptosis cells. Synonyms: (5Br-dUTP); 5-Bromo-2'-deoxyuridine-5'-triphosphate, Triethylammonium salt; 5-BrdUTP. Grades: ≥ 95% by HPLC. Molecular formula: C9H14N2O14P3Br (free acid). Mole weight: 547.04 (free acid).
5-Fluoro-dUTP
5-Fluoro-dUTP is used as the substitute for DNA synthesis catalyzed by DNA polymerases a or Ãfrom calf thymus. 5-Fluoro-dUTP is incorporated into DNA and the incorporated pyrimidine analogs supported further elongation of DNA. Synonyms: 5-F-dUTP; 5-Fl-dUTP; 5-Fluoro-2'-deoxyuridine-5'-Triphosphate. Grades: ≥ 95% by HPLC. Molecular formula: C9H14N2O14P3F (free acid). Mole weight: 486.13 (free acid).
5-Iodo-dUTP
5-Iodo-dUTP is used in the synthesis of Texas Red-5-dUTP, a fluorescence-labelled nucleotide analog. Texas Red-5-dUTP is used diagnostically for detection of rearranged SS18 in formalin-fixed, paraffin-embedded synovial sarcoma. Synonyms: 5-Iodo-2'-deoxyuridine-5'-Triphosphate. Grades: ≥ 95% by HPLC. CAS No. 3731-55-3. Molecular formula: C9H14N2O14P3I (free acid). Mole weight: 594.04 (free acid).
5-Trifluoromethyl-dUTP
5-Trifluoromethyl-dUTP, a modified nucleotide that has been specifically designed for the purpose of DNA labeling and detection, has become a popular choice for PCR-based assays aimed at identifying genetic variations and mutations within DNA sequences. With its incredible precision and versatility, it has become a critical tool for researchers investigating genetic diseases and identifying potential targets for therapeutic interventions. Synonyms: 5-Trifluoromethyl-2'-deoxyuridine-5'-triphosphate, Sodium salt. Grades: ≥ 95% by HPLC. Molecular formula: C10H14N2O14P3F3 (free acid). Mole weight: 536.14 (free acid).
6-FAM-11-dUTP
6-FAM-11-dUTP is a highly sought-after fluorescent nucleotide derivative in the field of compound research, employed as a distinguished probe. It bestows the ability to proficiently label DNA and RNA fragments within versatile frameworks like DNA sequencing, PCR compound labeling and even in situ hybridization. Consequently, this exceptional compound unfailingly facilitates the visualization and detection of nucleic acids, thereby cementing its worthiness as an indispensable tool in both molecular biology and diagnostics. Synonyms: 5-[3-(6-(fluoresceinyl-6-carboxamido)hexanoylamido)-propenyl]-2'-deoxyuridine-5'-triphosphate, triethylammonium or tetralithium (optional) salt. Grades: ≥ 95%.
Biotin-11-deoxyuridine-5'-triphosphate, triethylammonium salt
Biotin-11-deoxyuridine-5'-triphosphate, triethylammonium salt. Group: Biochemicals. Alternative Names: Biotin-11-dUTP. Grades: Highly Purified. Pack Sizes: 1mg, 2mg, 5mg, 10mg. US Biological Life Sciences.
Worldwide
Biotin-11-dUTP
Biotin-11-dUTP, a nucleotide analog of utmost significance, serves as a valuable tool in the labeling and detection of DNA. Synthetically engineered through the linkage of biotin and deoxyuridine triphosphate (dUTP) nucleotide, it seamlessly integrates with the DNA replication process. This paves the way for the detection of biotin-labeled DNA with the aid of streptavidin-conjugated reporters. Through the biotin-11-dUTP labeling, scientists worldwide have been able to further unravel the intricate processes of DNA replication, DNA repair, and gene expression analysis. Synonyms: Biotin-X-5-aminoallyl-dUTP; γ-[N-(Biotin-6-amino-hexanoyl)]-5-aminoallyl-2'-deoxyuridine-5'-triphosphate, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C28H45N6O17P3S (free acid). Mole weight: 862.67 (free acid).
Biotin-16-dUTP
Biotin-16-dUTP is a pivotal recompound employed in diverse biomedical application. Its prevalent utilization as a substrate for DNA labeling and detection methodologies, including PCR, DNA sequencing and in situ hybridization, underscores its indispensability. Synonyms: Biotin-16-5-aminoallyl-dUTP; γ-[N-(Biotin-6-amino-hexanoyl-6-aminobutanoyl)]-5-(3-aminoallyl)-2'-deoxyuridine-5'-triphosphate, Triethylammonium salt. Grades: ≥ 98% by HPLC. Molecular formula: C32H52N7O18P3S (free acid). Mole weight: 947.78 (free acid).
Biotin-18-dUTP
Biotin-18-dUTP, a biochemical utilized in enzymatic labeling of DNA fragments for purposes of detection and quantification, is a modified nucleotide analogue comprising of both biotin and deoxyuridine triphosphate. This multi-faceted compound plays an instrumental role within the biomedicine realm by providing researchers with a tool to study both the structure and function of DNA. It finds diverse application in the form of PCR, DNA sequencing and in situ hybridization, deftly pinpointing specific genes and mutations that may be associated with various diseases. Synonyms: Biotin-XX-5-aminoallyl-dUTP; γ-[N-(Biotin-6-amino-hexanoyl-6-aminohexanoyl)]-5-(3-aminoallyl)-2'-deoxyuridine-5'-triphosphate, Triethylammonium salt. Grades: ≥ 95% by HPLC. CAS No. 86303-25-5. Molecular formula: C34H56N7O18P3S (free acid). Mole weight: 975.83 (free acid).
Brivudine 5'-Triphosphate Ammonium
Brivudine 5'-Triphosphate Ammonium Salt is derived from Brivudine, which is a nucleoside analog which causes induction of neuronal differentiation in human reporter cell lines and adult stem cells. Anti-herpes medication. Synonyms: 5-(2-Bromovinyl)-2'-deoxyuridine-5'-triphosphate; [[(2R,3S,5R)-5-[5-[(E)-2-bromoethenyl]-2,4-dioxopyrimidin-1-yl]-3-hydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate; Uridine 5'-(tetrahydrogen triphosphate), 5-(2-bromoethenyl)-2'-deoxy-, (E)-; BVdUTP; BV(5)Dutp; Bvdu-tp; SCHEMBL442341; SCHEMBL442343; CHEMBL4594370; (E)-5-(2-Bromovinyl)-dUTP; Brivudine 5'-Triphosphate Ammonium; E-5-Bromovinyl-2'-deoxyuridine triphosphate; (E)-5-(2-Bromovinyl)-2'-deoxyuridine triphosphate; (e)-5-(2-bromovinyl)-2'-deoxyuridine 5'-triphosphate; Uridine 5'-(tetrahydrogen triphosphate), 5-[(1E)-2-bromoethenyl]-2'-deoxy-; ((2R,3S,5R)-5-(5-((E)-2-Bromovinyl)-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3-hydroxytetrahydrofuran-2-yl)methyl tetrahydrogen triphosphate; [[(2R,3S,5R)-5-[5-[(E)-2-bromovinyl]-2,4-dioxo-pyrimidin-1-yl]-3-hydroxy-tetrahydrofuran-2-yl]methoxy-hydroxy-phosphoryl] phosphono hydrogen phosphate. Molecular formula: C11H16BrN2O14P3. Mole weight: 573.08.
DEAC-dUTP
DEAC-dUTP is a remarkable nucleotide, finding application in the field of molecular biology studies. It contributes indispensably to endeavors encompassing DNA sequencing, PCR techniques and DNA labeling. Synonyms: Aminoallyl-dUTP - DEAC; Diethylaminocoumarin-5-dUTP; Diethylaminocoumarin-5-aminoallyl-2'-deoxyuridine-5'-triphosphate, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C26H33N4O17P3 (free acid). Mole weight: 766.48 (free acid).
DIG-11-dUTP
DIG-11-dUTP is an esteemed nucleotide analogue, adroitly employed for the purpose of DNA and RNA labeling. Employing this avant-garde compound alongside sophisticated methodologies including in situ hybridization and polymerase chain reaction (PCR) decidedly furnishes the remarkable ability to scrutinize distinctive nucleic acid sequences. Synonyms: Digoxigenin-X-5-aminoallyl-2'-deoxyuridine-5'-triphosphate, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C43H65N4O21P3 (free acid). Mole weight: 1066.91 (free acid).
FdUTP, a remarkable nucleoside triphosphate, puts the brakes on thymidylate synthase, striking a fatal blow to DNA precursor synthesis and culminating in cellular collapse. This versatile substance has proven tadpole in tackling a gamut of solid tumors, from the grisly colorectal specter to the dauntingly defiant breast cancer. Synonyms: 5-Fluoro-2'-deoxyuridine-5'-triphosphate. Grades: ≥ 95 % (HPLC). Molecular formula: C9H14N2O14P3F (free acid). Mole weight: 486.1 (free acid).
γ-[(6-Aminohexyl)-imido]-dUTP
γ-[(6-Aminohexyl)-imido]-dUTP is a nucleotide found in molecular biology research dedicated to DNA sequencing and labeling, serving as a crucial reagent in enzymatic labeling of DNA oligonucleotides. This modified nucleotide can also aid in the investigation of DNA-protein interactions implicated in diseases, such as genetic disorders and cancer. Synonyms: γ-[(6-Aminohexyl)-imido]-2'-deoxyuridine-5'-triphosphate. Grades: ≥ 95 % by HPLC. Molecular formula: C15H29N4O13P3(free acid). Mole weight: 566.33 (free acid).
γ-[(8-Aminooctyl)-imido]-dUTP
γ-[(8-Aminooctyl)-imido]-dUTP, a modified nucleotide with an 8-carbon linker, exhibits great potential in molecular biology applications. Labeling DNA with fluorescent dyes or biotin had never been so easy! This versatile and dynamic molecule has been demonstrated to be highly effective in a wide spectrum of exercises including DNA sequencing and Nucleic Acid amplification. Its applications even extend to the study of DNA-protein interactions and imaging! Synonyms: γ-[(8-Aminooctyl)-imido]-2'-deoxyuridine-5'-triphosphate. Grades: ≥ 95 % by HPLC. Molecular formula: C17H33N4O13P3(free acid). Mole weight: 594.38 (free acid).
Rhodamine-12-dUTP
Rhodamine-12-dUTP is a fluorescent nucleotide that can be incorporated into DNA during PCR amplification or nick translation to create labeled probes for detecting specific DNA sequences. This product is commonly used in biomedical research to study genetic variations, gene expression, and disease mechanisms. Its unique optical properties make it useful in applications such as fluorescence in situ hybridization (FISH) and single-cell sequencing. Synonyms: Rhodamine-X-5-Aminoallyl-dUTP; Rho-green-X-dUTP, RhG-dUTP, R110-dUTP; 5/6-Rhodamine-X-5-Aminoallyl-2'-deoxyuridine-5'-triphosphate, Triethylammonmium salt. Grades: ≥ 95 % by HPLC. Molecular formula: C39H43N6O19P3(free acid). Mole weight: 993.72 (free acid).
2'-Deoxyuridine-5'-[(a,b)-imido]triphosphate sodium salt
2'-Deoxyuridine-5'-[(a,b)-imido]triphosphate sodium salt. Group: Biochemicals. Alternative Names: dUpNHpp. Grades: Highly Purified. CAS No. 170428-86-1. Pack Sizes: 1mg. Molecular Formula: C9H16N3O13P3. US Biological Life Sciences.
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2'-Deoxyuridine-5'-[(a,b)-methyleno]triphosphate sodium salt
2'-Deoxyuridine-5'-[(a,b)-methyleno]triphosphate sodium salt. Group: Biochemicals. Alternative Names: dUpCpp. Grades: Highly Purified. CAS No. 170428-84-9. Pack Sizes: 1mg. Molecular Formula: C10H17N2O13P3. US Biological Life Sciences.
Worldwide
2-Deoxyuridine 5-Triphosphate, Sodium Salt (dUTP) Solution
2?-Deoxyuridine 5?-triphosphate (dUTP) may be used to study the distribution, specificity and kinetics of deoxyuridine 5?-triphosphate nucleotidohydrolase(s) (dUTPase, EC 3.6.1.23). dUTPase are important enzymes that protect cells from the incorporation of dUTP into DNA.dUTP is a component of the TUNEL (terminal deoxyribonucleotidyl-transferase-(TdT)-mediated deoxyuridine-5?-triphosphate- (dUTP) nick-end labeling) test. TUNEL is a common method for detecting DNA fragmentation that results from apoptotic signaling cascades. Group: Biochemicals. Grades: Molecular Biology Grade. CAS No. 102814-08-4. Pack Sizes: 100mM. US Biological Life Sciences.
Worldwide
ANX-510
ANX-510 is a folate-based biomodulator with potential antineoplastic activity. 5,10-methylenetetrahydrofolate (MTHF) stabilizes the covalent binding of the fluorouracil metabolite 5-5-fluoro-2'-deoxyuridine-5'-O-monophosphate (FdUMP) to its target enzyme, thymidylate synthase, which results in inhibition of thymidylate synthase, depletion of thymidine triphosphate (TTP), a necessary constituent of DNA, and tumor cell death. Synonyms: 5,10-Methylenetetrahydrofolic acid; 5,10-Methylene-tetrahydrofolate; Tetrahydromethylenefolate; N-{4-[3-amino-1-oxo-1,2,5,6,6a,7-hexahydroimidazo[1,5-f]pteridin-8(9H)-yl]benzoyl}-L-glutamic acid. CAS No. 3432-99-3. Molecular formula: C20H23N7O6. Mole weight: 457.44.
dUpCpp
dUpCpp - a chemical compound utilized in the field of biomedical research - holds promising potential as an enzyme activator which facilitates DNA and RNA replication. By augmenting the function of polymerases essential for viral replication, this unique substance presents a promising target for antiviral drug development. Furthermore, dUpCpp has been utilized to probe and unravel the mechanisms underlying the polymerization of DNA and RNA in a spectrum of systems. Synonyms: dUMPCPP; 2'-Deoxyuridine-5'-[(α,β)-methyleno]triphosphate, Sodium salt. Grades: ≥ 95 % by HPLC. CAS No. 170428-84-9. Molecular formula: C10H17N2O13P3.xNa. Mole weight: 466.17 (free acid).
dUpNHpp
dUpNHpp, a formidable small molecule inhibitor with potential therapeutic benefits, is a contender in the battle against cancer. Its mode of action rests on disrupting protein-protein interactions, resulting in the arrest of tumor growth. Ovarian and breast cancer, both notorious for their lethality, have been subject to clinical trials with auspicious outcomes. Synonyms: dUMPNPP;2'-Deoxyuridine-5'-[(α,β)-imido]triphosphate, Sodium salt. Grades: ≥ 95 % by HPLC. CAS No. 170428-86-1. Molecular formula: C9H16N3O13P3.xNa. Mole weight: 467.15 (free acid).
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