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1,8-Naphthyridine,7-(3-fluorophenoxy)-2,4-bis(trifluoromethyl)-(9ci). Uses: Designed for use in research and industrial production. Additional or Alternative Names: 1,8-Naphthyridine,7-(3-fluorophenoxy)-2,4-bis(trifluoromethyl)-(9CI). Product Category: Heterocyclic Organic Compound. CAS No. 303996-21-6. Molecular formula: C16H7F7N2O. Product ID: ACM303996216. Alfa Chemistry ISO 9001:2015 Certified.
AMDE-1
AMDE-1 is a modulator of autophagy activity. It acts by triggering autophagy in an Atg5-dependent manner, recruiting Atg16 to the pre-autophagosomal site and causing LC3 lipidation. Synonyms: AMDE 1; alpha-(3-Chlorophenyl)-5,7-bis(trifluoromethyl)-1,8-naphthyridine-2-acetonitrile; Autophagy Modulator with Dual Effect-1. CAS No. 478043-30-0. Molecular formula: C18H8ClF6N3. Mole weight: 415.72.
1,8-Naphthyridin-2-amine,N-(2,4-dichlorophenyl)-5,7-bis(trifluoromethyl)-(9ci). Uses: Designed for use in research and industrial production. Additional or Alternative Names: 1,8-Naphthyridin-2-amine,N-(2,4-dichlorophenyl)-5,7-bis(trifluoromethyl)-(9CI). Product Category: Heterocyclic Organic Compound. CAS No. 241488-38-0. Molecular formula: C16H7Cl2F6N3. Product ID: ACM241488380. Alfa Chemistry ISO 9001:2015 Certified.
1-Benzyl-2,5-pyrrolidinedione
1-Benzyl-2,5-pyrrolidinedione is an intermediate in synthesizing 2,3,4,10-Tetrahydro-1H-indolo[2,3-b][1,8]naphthyridin-2-ol (T294270), a derivative of 6, 7, 8, 9-Tetrahydro-7-hydroxy-5-methyl-3-phenyl-pyrido[3, 2:4, 5]imidazo[1, 2-a]pyrimidinium Chloride (H957770), a carcinogen used in the study of intestinal bacteria metabolism. Created through the heat processing of food. Group: Biochemicals. Grades: Highly Purified. CAS No. 2142-6-5. Pack Sizes: 500mg, 1g. Molecular Formula: C11H11NO2. US Biological Life Sciences.
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1-Benzyl-2-chloro-1H-indole-3-carboxaldehyde
1-Benzyl-2-chloro-1H-indole-3-carboxaldehyde is an intermediate in synthesizing 2,3,4,10-Tetrahydro-1H-indolo[2,3-b][1,8]naphthyridin-2-ol (T294270), a derivative of 6, 7, 8, 9-Tetrahydro-7-hydroxy-5-methyl-3-phenyl-pyrido[3, 2:4, 5]imidazo[1, 2-a]pyrimidinium Chloride (H957770), a carcinogen used in the study of intestinal bacteria metabolism. Created through the heat processing of food. Group: Biochemicals. Grades: Highly Purified. CAS No. 77655-46-0. Pack Sizes: 500mg, 1g. Molecular Formula: C16H12ClNO. US Biological Life Sciences.
1-? (Phenyl methyl ) ?-?2-? [ (tri phenylphosphora?nylide ne ) ?amino] ?-1H-?indole-?3-?carboxalde hyde is an intermediate in synthesizing 2,3,4,10-Tetrahydro-1H-indolo[2,3-b][1,8]naphthyridin-2-ol (T294270), a derivative of 6, 7, 8, 9-Tetrahydro-7-hydroxy-5-methyl-3-phenyl-pyrido[3, 2:4, 5]imidazo[1, 2-a]pyrimidinium Chloride (H957770), a carcinogen used in the study of intestinal bacteria metabolism. Created through the heat processing of food. Group: Biochemicals. Grades: Highly Purified. CAS No. 134370-12-0. Pack Sizes: 50mg, 100mg. Molecular Formula: C34H27N2OP. US Biological Life Sciences.
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2-(1,8-Naphthyridin-2-yl)-phenol
2-(1,8-naphthyridin-2-yl)-Phenol is which selectively enhances STAT1 transcription activity. Group: Biochemicals. Grades: Highly Purified. CAS No. 65182-56-1. Pack Sizes: 25mg, 50mg. Molecular Formula: C14H10N2O, Molecular Weight: 222.24. US Biological Life Sciences.
2,3,4,10-Tetrahydro-1H-indolo[2,3-b][1,8]naphthyridin-2-ol is a derivative of 6, 7, 8, 9-Tetrahydro-7-hydroxy-5-methyl-3-phenyl-pyrido[3, 2:4, 5]imidazo[1, 2-a]pyrimidinium Chloride (H957770), a carcinogen used in the study of intestinal bacteria metabolism. Created through the heat processing of food. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 5mg. Molecular Formula: C14H13N3O. US Biological Life Sciences.
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2,7-Dichloro-1,8-naphthyridine
2,7-Dichloro-1,8-naphthyridine. Group: Biochemicals. Grades: Highly Purified. CAS No. 55243-02-2. Pack Sizes: 10mg, 25mg, 50mg, 100mg, 250mg. Molecular Formula: C8H4Cl2N2. US Biological Life Sciences.
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2-Amino-[1,8]naphthyridine-3-carbonitrile
2-Amino-[1,8]naphthyridine-3-carbonitrile. Group: Biochemicals. Grades: Highly Purified. CAS No. 15935-95-2. Pack Sizes: 100mg, 250mg. Molecular Formula: C9H6N4, Molecular Weight: 170.17. US Biological Life Sciences.
2-?Amino-?1-?(phenylmethyl)?-1H-?indole-?3-?carboxaldehyde is an intermediate in synthesizing 2,3,4,10-Tetrahydro-1H-indolo[2,3-b][1,8]naphthyridin-2-ol (T294270), a derivative of 6, 7, 8, 9-Tetrahydro-7-hydroxy-5-methyl-3-phenyl-pyrido[3, 2:4, 5]imidazo[1, 2-a]pyrimidinium Chloride (H957770), a carcinogen used in the study of intestinal bacteria metabolism. Created through the heat processing of food. Group: Biochemicals. Grades: Highly Purified. CAS No. 126177-49-9. Pack Sizes: 5mg, 10mg. Molecular Formula: C16H14N2O. US Biological Life Sciences.
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2-Amino-6-iodo-[1,8]naphthyridine-3-carbonitrile
2-Amino-6-iodo-[1,8]naphthyridine-3-carbonitrile is used in the modification of radioiodination targets. Group: Biochemicals. Grades: Highly Purified. CAS No. 578007-69-9. Pack Sizes: 25mg, 50mg. Molecular Formula: C9H5IN4, Molecular Weight: 296.07. US Biological Life Sciences.
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2-Amino-6-methyl-1,8-naphthyridine-3-carbonitrile
2-Amino-6-methyl-1,8-naphthyridine-3-carbonitrile. Group: Biochemicals. Grades: Highly Purified. CAS No. 1203499-48-2. Pack Sizes: 10mg, 25mg. Molecular Formula: C10H8N4, Molecular Weight: 184.2. US Biological Life Sciences.
2-Amino-7-chloro-1-ethyl-1,4-dihydro-N-methyl-4-oxo-1,8-naphthyridine-3-carboxamide is an intermediate in the synthesis of SAR131675 (S139510), is a potent and selective VEGFR-3 inhibitor. Group: Biochemicals. Alternative Names: 2-Amino-7-chloro-1-ethyl-1,4-dihydro-N-methyl-4-oxo-1,8-naphthyridine-3-carboxamide. Grades: Highly Purified. CAS No. 1092523-24-4. Pack Sizes: 50mg. US Biological Life Sciences.
2-?Azido-?1-?(phenylmethyl)?-1H-?indole-?3-?carboxaldehyde is an intermediate in synthesizing 2,3,4,10-Tetrahydro-1H-indolo[2,3-b][1,8]naphthyridin-2-ol (T294270), a derivative of 6, 7, 8, 9-Tetrahydro-7-hydroxy-5-methyl-3-phenyl-pyrido[3, 2:4, 5]imidazo[1, 2-a]pyrimidinium Chloride (H957770), a carcinogen used in the study of intestinal bacteria metabolism. Created through the heat processing of food. Group: Biochemicals. Grades: Highly Purified. CAS No. 126177-54-6. Pack Sizes: 100mg, 250mg. Molecular Formula: C16H12N4O. US Biological Life Sciences.
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2-Benzylamino-3-ethylester-9H-pyrido[2,3-b]indole
2-Benzylamino-3-ethylester-9H-pyrido[2,3-b]indole is an intermediate in synthesizing 2,3,4,10-Tetrahydro-1H-indolo[2,3-b][1,8]naphthyridin-2-ol (T294270), a derivative of 6, 7, 8, 9-Tetrahydro-7-hydroxy-5-methyl-3-phenyl-pyrido[3, 2:4, 5]imidazo[1, 2-a]pyrimidinium Chloride (H957770), a carcinogen used in the study of intestinal bacteria metabolism. Created through the heat processing of food. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 25mg, 50mg. Molecular Formula: C28H25N3O2. US Biological Life Sciences.
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2-Benzylisoindoline-4-carboxylic Acid
2-Benzylisoindoline-4-carboxylic Acid is used in the preparation of 7-(2-Isoindolinyl)-1,4-dihydro-4-oxoquinoline and 1,8-naphthyridine-3-carboxylic Acid derivative as strong anti-bacterial activity against gram negative and positive microorganisms. Group: Biochemicals. Grades: Highly Purified. CAS No. 127169-17-9. Pack Sizes: 25mg, 50mg. Molecular Formula: C16H15NO2, Molecular Weight: 253.3. US Biological Life Sciences.
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2-Methyl-6-(trifluoromethyl)-1,8-naphthyridine
2-Methyl-6-(trifluoromethyl)-1,8-naphthyridine. Group: Biochemicals. Grades: Highly Purified. CAS No. 1261365-74-5. Pack Sizes: 25mg, 50mg. Molecular Formula: C10H7F3N2, Molecular Weight: 212.17. US Biological Life Sciences.
3-? [2-?Chloro-?1-? (phenylmethyl) ?-?1H-?indol-?3-?yl] ?-?2-?cyano-?2-?propenoic Acid is an intermediate in synthesizing 2,3,4,10-Tetrahydro-1H-indolo[2,3-b][1,8]naphthyridin-2-ol (T294270), a derivative of 6, 7, 8, 9-Tetrahydro-7-hydroxy-5-methyl-3-phenyl-pyrido[3, 2:4, 5]imidazo[1, 2-a]pyrimidinium Chloride (H957770), a carcinogen used in the study of intestinal bacteria metabolism. Created through the heat processing of food. Group: Biochemicals. Grades: Highly Purified. CAS No. 188034-08-4. Pack Sizes: 25mg, 50mg. Molecular Formula: C21H17ClN2O2. US Biological Life Sciences.
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3,4-Dihydro-1H-[1,8]naphthyridin-2-one
3,4-Dihydro-1H-[1,8]naphthyridin-2-one. Group: Biochemicals. Grades: Highly Purified. CAS No. 40000-79-1. Pack Sizes: 25mg, 50mg, 100mg, 250mg, 500mg. US Biological Life Sciences.
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3,4-Dihydro-1H-[1,8]naphthyridin-2-one ≥96%
3,4-Dihydro-1H-[1,8]naphthyridin-2-one ≥96%. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 100mg, 250mg, 25mg, 1g. US Biological Life Sciences.
3-?[ (Dimethylamino) ?methylene]?-?1, ?3-?dihydro-?1-? (phenylmethyl) ?-2H-?indol-?2-?one is an intermediate in synthesizing 2,3,4,10-Tetrahydro-1H-indolo[2,3-b][1,8]naphthyridin-2-ol (T294270), a derivative of 6, 7, 8, 9-Tetrahydro-7-hydroxy-5-methyl-3-phenyl-pyrido[3, 2:4, 5]imidazo[1, 2-a]pyrimidinium Chloride (H957770), a carcinogen used in the study of intestinal bacteria metabolism. Created through the heat processing of food. Group: Biochemicals. Grades: Highly Purified. CAS No. 221642-05-3. Pack Sizes: 100mg, 250mg. Molecular Formula: C18H18N2O. US Biological Life Sciences.
3-[ (Dimethylamino) methylene]-1, 3-dihydro-2H-indol-2-one is an intermediate in synthesizing 2,3,4,10-Tetrahydro-1H-indolo[2,3-b][1,8]naphthyridin-2-ol (T294270), a derivative of 6, 7, 8, 9-Tetrahydro-7-hydroxy-5-methyl-3-phenyl-pyrido[3, 2:4, 5]imidazo[1, 2-a]pyrimidinium Chloride (H957770), a carcinogen used in the study of intestinal bacteria metabolism. Created through the heat processing of food. Group: Biochemicals. Grades: Highly Purified. CAS No. 57315-91-0. Pack Sizes: 500mg, 1g. Molecular Formula: C11H12N2O. US Biological Life Sciences.
Intermediate in the production of FabI inhibitors. Group: Biochemicals. Alternative Names: Methyl 6-Bromo-2-oxo-1, 2, 3, 4-tetrahydro[1, 8]naphthyridine-3-carboxylate. Grades: Highly Purified. CAS No. 335031-10-2. Pack Sizes: 1g. US Biological Life Sciences.
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6-Bromo-3,4-dihydro-1H-[1,8]naphthyridin-2-one
6-Bromo-3,4-dihydro-1H-[1,8]naphthyridin-2-one. Group: Biochemicals. Alternative Names: 6-Bromo-3,4-dihydro-1,8-naphthyridin-2(1H)-one. Grades: Highly Purified. CAS No. 129686-16-4. Pack Sizes: 100mg. US Biological Life Sciences.
7-Chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic Acid Ethyl Ester is a fluoroquinolone derivative used in the preparation of antibacterial agents. Group: Biochemicals. Alternative Names: 7-Chloro-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydro-[1,8]naphthyridine-3-carboxylic Acid Ethyl Ester. Grades: Highly Purified. CAS No. 96568-07-9. Pack Sizes: 2.5g. US Biological Life Sciences.
7-Chloro-6-fluoro-1-(2,4-difluorophenyl)-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acid ethyl ester. Group: Biochemicals. Alternative Names: 7-Chloro-1-(2,4-difluorophenyl)-6-fluoro-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acid ethyl ester. Grades: Highly Purified. CAS No. 100491-29-0. Pack Sizes: 10mg, 25mg, 50mg, 100mg, 250mg. Molecular Formula: C17H10ClF3N2O3. US Biological Life Sciences.
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Alatrofloxacin Mesylate
The parental prodrug of Trovafloxacin, on phagocytic, anti-inflammatory and immunomodulation events of human THP-1 monocytes. Group: Biochemicals. Alternative Names: L-Alanyl-N-[(1α, 5α, 6α)-3-[6-carboxy-8-(2, 4-difluorophenyl)-3-fluoro-5, 8-dihydro-5-oxo-1, 8-naphthyridin-2-yl]-3-azabicyclo[3.1.0]hex-6-yl]-L-alaninamide Methanesulfonate; L-Alanyl-N-[(1α, 5α, 6α)-3-[6-carboxy-8-(2, 4-difluorophenyl)-3-fluoro-5, 8-dihydro-5-oxo-1, 8-naphthyridin-2-yl]-3-azabicyclo[3.1.0]hex-6-yl]-L-alaninamide Mesylate. Grades: Highly Purified. CAS No. 146961-77-5. Pack Sizes: 10mg. US Biological Life Sciences.
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Desmethoxyamino Hydroxy Gemifloxacin
Desmethoxyamino Hydroxy Gemifloxacin. Group: Biochemicals. Alternative Names: 7-(3-(Aminomethyl)-4-hydroxypyrrolidin-1-yl)-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic Acid. Grades: Highly Purified. CAS No. 213672-25-4. Pack Sizes: 10mg. Molecular Formula: C17H18FN4O4, Molecular Weight: 362.36. US Biological Life Sciences.
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Enoxacin
A fluororquinolone antibacterial used to treat urinary tract infections and gonorrhea. Group: Biochemicals. Alternative Names: 1-Ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-1,8-naphthyridine-3-carboxylic Acid; Enofloxacin; Enofloxacine; Enoksetin; Flumark; NSC 629661; PD 107779; Penetrex. Grades: Highly Purified. CAS No. 74011-58-8. Pack Sizes: 1g. US Biological Life Sciences.
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Enoxacin Sesquihydrate
Enoxacin Sesquihydrate. Group: Biochemicals. Alternative Names: 1-Ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-1,8-naphthyridine-3-carboxylic Acid Sesquihydrate. Grades: Highly Purified. CAS No. 84294-96-2. Pack Sizes: 5g, 10g, 25g, 50g, 100g. US Biological Life Sciences.
Ethyl 1-cyclopropyl-7-chloro-6-fluoro-1,4-dihydro-4-oxo-1,8-naphthyridine carboxylate. Group: Biochemicals. Grades: Reagent Grade. CAS No. 96568-07-9. Pack Sizes: 250mg, 1g, 5g. US Biological Life Sciences.
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Gemifloxacin-13C2,d2
Third generation fluorinated quinolone antibacterial. Group: Biochemicals. Alternative Names: 7-[3-(Aminomethyl)-4-(methoxyimino)-1-pyrrolidinyl]-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic Acid-13C2,d2; SB-265805-13C2,d2; LB-20304-13C2,d2. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
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Gemifloxacin mesilate
Gemifloxacin mesilate. Group: Biochemicals. Alternative Names: 7-[3-(Aminomethyl)-4-(methoxyimino)-1-pyrrolidinyl]-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acid mesilate; SB-265805 mesilate; LB-20304 mesilate. Grades: Highly Purified. CAS No. 210353-53-0. Pack Sizes: 10mg, 25mg, 50mg, 100mg, 250mg. Molecular Formula: C19H24FN5O7S. US Biological Life Sciences.
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MK0873
MK0873 is a phosphodiesterase 4 (PDE4) inhibitor. It has shown as an innovative tool to design topical formulation to achieve desired pharmacokinetics in humans along with a minipig skin biopsy model. It was developed by Merck. It was used to treat rheumatoid arthritis in phase II clinical trials and plaque psoriasis in phase I clinical trials, but it has no recent research progress. Uses: Mk0873 was used to treat rheumatoid arthritis and plaque psoriasis. Synonyms: N-cyclopropyl-1-[3-[2-(1-oxidopyridin-1-ium-3-yl)ethynyl]phenyl]-4-oxo-1,8-naphthyridine-3-carboxamide;MK0873; MK 0873; MK-0873;3-((3-(3-(cyclopropylcarbamoyl)-4-oxo-1,8-naphthyridin-1(4H)-yl)phenyl)ethynyl)pyridine 1-oxide. Grades: 98%. CAS No. 500355-52-2. Molecular formula: C25H18N4O3. Mole weight: 422.44.
Nalidixic Acid, 98+%
Inhibitor of bacterial DNA synthesis. Nalidixic acid is the first of the synthetic quinolone antibiotics. It is a naphthyridone, not a quinolone: its ring structure is a 1,8-naphthyridine nucleus that contains two nitrogen atoms, unlike quinoline, which has a single nitrogen atom.[1] Synthetic quinolone antibiotics were discovered by George Lesher and coworkers as a byproduct of chloroquine manufacture in the 1960s.[1] Used clinically from 1967.[1]. Group: Biochemicals. Alternative Names: 1,4-Dihydro-1-ethyl-7-methyl-1,8-naphthyridin-4-one-3-carboxylic acid; 1-Ethyl-1,4-dihydro-7-methyl-4-oxo-1,8-naphthyridine-3-carboxylic acid. Grades: Highly Purified. CAS No. 389-08-2. Pack Sizes: 100g, 250g, 500g, 1Kg. Molecular Formula: C12H12N2O3. US Biological Life Sciences.
Worldwide
Nalidixic Acid 99+%
Inhibitor of bacterial DNA synthesis. Nalidixic acid is the first of the synthetic quinolone antibiotics. It is a naphthyridone, not a quinolone: its ring structure is a 1,8-naphthyridine nucleus that contains two nitrogen atoms, unlike quinoline, which has a single nitrogen atom.[1] Synthetic quinolone antibiotics were discovered by George Lesher and coworkers as a byproduct of chloroquine manufacture in the 1960s.[1] Used clinically from 1967.[1]. Group: Biochemicals. Alternative Names: 1-Ethyl-1,4-dihydro-7-methyl-4-oxo-1,8-naphthyridine-3-carboxylicAcid; 1,4-Dihydro-1-ethyl-7-methyl-4-oxo-1,8-naphthyridine-3-carboxylic Acid; Betaxina; Cybis; Dixiben; Eucistin; NegGram; Nelidix; Win 18320; Wintomylon. Grades: Highly Purified. CAS No. 389-08-2. Pack Sizes: 25g, 100g. US Biological Life Sciences.
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Nalidixic Acid-d5
Inhibitor of bacterial DNA synthesis. Nalidixic acid is the first of the synthetic quinolone antibiotics. It is a naphthyridone, not a quinolone: its ring structure is a 1,8-naphthyridine nucleus that contains two nitrogen atoms, unlike quinoline, which has a single nitrogen atom.[1] Synthetic quinolone antibiotics were discovered by George Lesher and coworkers as a byproduct of chloroquine manufacture in the 1960s.[1] Used clinically from 1967.[1]. Group: Biochemicals. Alternative Names: 1-(Ethyl-d5)-1,4-dihydro-7-methyl-4-oxo-1,8-naphthyridine-3-carboxylic Acid;1,4-Dihydro-1-(ethyl-d5)-7-methyl-4-oxo-1,8-naphthyridine-3-carboxylic Acid; Betaxina-d5; Cybis-d5; Dixiben-d5; Eucistin-d5; NegGram-d5; Nelidix-d5; Win 18320-d5; Wintomylon-d5. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
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Nalidixic acid sodium salt
Nalidixic acid sodium salt. Group: Biochemicals. Alternative Names: 1-Ethyl-1,4-dihydro-7-methyl-4-oxo-1,8-naphthyridine-3-carboxylic acid sodium salt. Grades: Highly Purified. CAS No. 3374-5-8. Pack Sizes: 25g, 50g, 100g, 250g, 500g. Molecular Formula: C12H11N2NaO3. US Biological Life Sciences.
Worldwide
PP2A Activating Ligand, ITH12246
A cell-permeable, relatively non-toxic, 1,8-naphthyridine derived compound that blocks the inhibitory effect of protein phosphatase inhibitors, such as okadaic acid, on protein phosphatase 2A (PP2A). Exhibits blood-brain barrier permeability. Protects neurons against beta-amyloid peptides (Ab1-42) toxicity and okadaic acid-induced tau hyperphosphorylation. Also protects against rotenone and oligomycin A induced neurotoxicity in SH-SY5Y neuroblastoma cells (at ~300nM). Prevents the development of glutamate-induced neuronal lesions in rat hippocampal slices by up-regulating PP2A (~3uM). Shown to reverse the scopolamine-induced memory loss in mice (~10mg/kg i.p) and significantly reduces the infarct volume in an animal model of stroke (~2.5mg/kg). Also acts as an inhibitor of acetylcholinesterase activity in Electrophorus electricus (IC50 = 60nM) and human erythrocytes (IC50 = 780nM). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. Molecular Formula: C??H??N?O?·HCl. US Biological Life Sciences.
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RO8191
RO8191 is an agonist of interferon α receptor type 2 (IFNAR2) effective against HCV with EC50 value of 200 nM. RO8191 phosphorylates STAT1 and STAT2, which functions as a gateway to the type I IFN signal cascade, and stimulates the phosphorylation of STAT3, 5 and 6. Synonyms: Ro 494-8191; 2-[2,4-bis(trifluoromethyl)imidazo[1,2-a]1,8-naphthyridin-8-yl]-1,3,4-oxadiazole; 8-(1,3,4-oxadiazol-2-yl)-2,4-bis(trifluoromethyl)imidazo[1,2-a][1,8]naphthyridine. Grades: ≥98%. CAS No. 691868-88-9. Molecular formula: C14H5F6N5O. Mole weight: 373.2.
SAR131675
SAR131675 is a potent and selective VEGFR-3 inhibitor. It inhibited VEGFR-3 tyrosine kinase activity and VEGFR-3 autophosphorylation in HEK cells. SAR131675 also dose dependently inhibited the proliferation of primary human lymphatic cells, induced by the VEGFR-3 ligands VEGFC and VEGFD. Group: Biochemicals. Alternative Names: 2-Amino-1-ethyl-7-(3-hydroxy-4-methoxy-3-methyl-1-butyn-1-yl)-N-methyl-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxamide; 2-Amino-1-ethyl-1,4-dihydro-7-(3-hydroxy-4-methoxy-3-methyl-1-butyn-1-yl)-N-methyl-4-oxo-1,8-naphthyridine-3-carboxamide. Grades: Highly Purified. CAS No. 1092538-80-1. Pack Sizes: 25mg, 50mg. Molecular Formula: C??H??N?O?, Molecular Weight: 358.39. US Biological Life Sciences.
Worldwide
Tosufloxacin Toluenesulfonate Hydrate
Useful as a therapeutic antimicrobial for the treatment of respiratory infections. Group: Biochemicals. Alternative Names: 7-(3-Amino-1-pyrrolidinyl)-(2,4-difluorophenyl)-6-fluoro-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic Acid Toluenesulfonate Hydrate; Tosufloxacin Tosylate; A-64730; T-3262; Ozax; Tosuxacin. Grades: Highly Purified. CAS No. 115964-29-9. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
Trovafloxacin Mesylate
Fluorinated quinolone antibacterial. Trovafloxacin mesylate blocks the activity of DNA gyrase and topoisomerase IV, enzymes essential in the repliction, transcription, and repair of bacterial DNA. Group: Biochemicals. Alternative Names: 7-[(1α, 5α, 6α)-6-Amino-3-azabicyclo[3.1.0]hex-3-yl]-1-(2, 4-difluorophenyl)-6-fluoro-1, 4-dihydro-4-oxo-1, 8-naphthyridine-3-carboxylic Acid Methanesulfonate; CP 99219; CP 99219-27; Trovafloxacin Methanesulfonate; Trovafloxacin Monomethanesulfonate; Trovan. Grades: Highly Purified. CAS No. 147059-75-4. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
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