3543-75-7 suppliers USA

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Bendamustine hydrochloride Bendamustine hydrochloride. Group: Biochemicals. Alternative Names: 5-[Bis(2-chloroethyl)-amino]-1-methyl-1H-benzimidazole-2-butanoic acid hydrochloride; Cytostasan; Ribomustin. Grades: Highly Purified. CAS No. 3543-75-7. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C16H22Cl3N3O2. US Biological Life Sciences. USBiological 6
Worldwide
Bendamustine hydrochloride Bendamustine hydrochloride is the hydrochloride salt of bendamustine, a bifunctional mechlorethamine derivative with alkylator and antimetabolite activities. Bendamustine possesses three active moieties: an alkylating group; a benzimidazole ring, which may act as a purine analogue; and a butyric acid side chain. Although its exact mechanism of action is unknown, this agent appears to act primarily as an alkylator. Bendamustine metabolites alkylate and crosslink macromolecules, resulting in DNA, RNA and protein synthesis inhibition, and, subsequently, apoptosis. Bendamustine may differ from other alkylators in that it may be more potent in activating p53-dependent stress pathways and inducing apoptosis; it may induce mitotic catastrophe; and it may activate a base excision DNA repair pathway rather than an alkyltransferase DNA repair mechanism. Synonyms: SDX-105 (Cytostasane) HCl; SDX 105 (Cytostasane) HCl; SDX105 (Cytostasane) HCl. Grade: >98%. CAS No. 3543-75-7. Molecular formula: C16H21Cl2N3O2.HCl. Mole weight: 394.72. BOC Sciences 2
Bendamustine hydrochloride Bendamustine hydrochloride (SDX-105), a purine analogue, is a DNA cross-linking agent. Bendamustine hydrochloride activats DNA-damage stress response and apoptosis. Bendamustine hydrochloride has potent alkylating, anticancer and antimetabolite properties [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SDX-105. CAS No. 3543-75-7. Pack Sizes: 10 mM * 1 mL; 25 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-B0077. MedChemExpress MCE
Bendamustine hydrochloride Bendamustine hydrochloride. Uses: Designed for use in research and industrial production. Additional or Alternative Names: bendamustine hydrochloride;BENDAMUSTIN HYDROCHLORIDE;CYTOSTASAN;1-methyl-5-bis(2-chloroethyl)amino-2-benzimidazolinebutryric acid hydrochloride;4-[5-[bis(2-chloroethyl)amino]-1-methylbenzimidazol-2-yl]butanoic acid hydrochloride;1-methyl-5-bis(2-chloroethyl)amino-2-benzimidazolinebutryricacihydrochlor;gamma(1-methyl-5-bis(beta-chloraethyl)aminobenzimidazoyl-2)buttersaeurehydro;BENDAMUSTINE HCL. Appearance: powder. CAS No. 3543-75-7. Molecular formula: C16H22Cl3N3O2. Mole weight: 394.72. Purity: 98%+. IUPACName: 4-[5-[bis(2-chloroethyl)amino]-1-methylbenzimidazol-2-yl]butanoicacid;hydrochloride. Canonical SMILES: CN1C2=C(C=C(C=C2)N(CCCl)CCCl)N=C1CCCC(=O)O.Cl. Product ID: ACM3543757. Alfa Chemistry — ISO 9001:2015 Certified. Alfa Chemistry. 2
BendaMustine Hydrochloride Bendamustine hydrochloride monotherapy or combination therapy has been designated by European and American clinical guidelines as a first - or second-line treatment option for a variety of hematological malignancies. CAS No. 3543-75-7. Product ID: PAP-0094. Molecular formula: C16H22Cl3N3O2. Product Keywords: Other Active Pharmaceutical Ingredients; BendaMustine Hydrochloride; PAP-0094; ; C16H22Cl3N3O2; 3543-75-7. Appearance: Powder. Color: off-white. EC Number: 631-540-0. Physical State: powder. Solubility: H2O: >30mg/mL. Storage: room temp. Applications: Treatment of Chronic Lymphocytic Leukemia (CLL). Melting Point: 149-151°C. CD Formulation

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