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Myriocin Myriocin is a atypical amino acid and an antibiotic with potent immunosuppressant activity. Studies suggest that the immunosuppressant activity in the cytotoxic T-cell line CTTL-2 is due to apoptosis induction. Myriocin very potent inhibitor of serine palmitoyltransferase and thus blocks the synthesis ceramide, a precursor in sphingomyelin and glycosphingolipid biosynthesis. As a result Myriocin is a useful biochemical research tool for depleting cells of sphingolipids. Group: Biochemicals. Alternative Names: (2S,3R,4R,6E)-2-Amino-3,4-dihydroxy-2-(hydroxymethyl)-14-oxo-6-eicosenoic Acid; [2S-(2R*,3S*,4S*,6E)]-2-Amino-3,4-dihydroxy-2-(hydroxymethyl)-14-oxo-6-eicosenoic Acid; (+)-Myriocin; ISP-I; NSC 177379; Thermozymocidin; (2S,3R,4R)-(E)-2-Amino-3,4-dihydroxy-2-hydroxymethyl-14-oxoeicos-6-enoic Acid. Grades: Highly Purified. CAS No. 35891-70-4. Pack Sizes: 5mg. US Biological Life Sciences. USBiological 2
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Myriocin Myriocin is an unsaturated hydrocarbon and fatty acid derivative produced by Myriococcum albomyces NRRL 3858. It has antifungal activity. Synonyms: thermozymocidin. Grades: >97% by HPLC. CAS No. 35891-70-4. Molecular formula: C21H39NO6. Mole weight: 401.54. BOC Sciences 5
Myriocin Myriocin (Thermozymocidin), a fungal metabolite could be isolated from Myriococcum albomyces , Isaria sinclairi and Mycelia sterilia , is a potent inhibitor of serine-palmitoyl-transferase (SPT) and a key enzyme in de novo synthesis of sphingolipids. Myriocin suppresses replication of both the subgenomic HCV-1b replicon and the JFH-1 strain of genotype 2a infectious HCV, with an IC 50 of 3.5 μg/mL for inhibiting HCV infection [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: Thermozymocidin; ISP-I. CAS No. 35891-70-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-N6798. MedChemExpress MCE
Myriocin Myriocin (Thermozymocidin), a fungal metabolite could be isolated from Myriococcum albomyces, Isaria sinclairi and Mycelia sterilia, is a potent inhibitor of serine-palmitoyl-transferase (SPT) and a key enzyme in de novo synthesis of sphingolipids. Myriocin suppresses replication of both the subgenomic HCV-1b replicon and the JFH-1 strain of genotype 2a infectious HCV, with an IC50 of 3.5 μg/mL for inhibiting HCV infection. Uses: Designed for use in research and industrial production. Additional or Alternative Names: (2S,3R,4R,6E)-2-Amino-3,4-dihydroxy-2-(hydroxymethyl)-14-oxo-6-eicosenoic acid. Product Category: Inhibitors. Appearance: Off-white solid. CAS No. 35891-70-4. Molecular formula: C21H39NO6. Mole weight: 401.54. Purity: >98%. IUPACName: (E,2S,3R,4R)-2-amino-3,4-dihydroxy-2-(hydroxymethyl)-14-oxoicos-6-enoic acid. Canonical SMILES: CCCCCCC(=O)CCCCCC/C=C/C[C@H]([C@@H]([C@@](CO)(C(=O)O)N)O)O. Density: 1.123±0.06 g/cm3(Predicted). Product ID: ACM35891704. Alfa Chemistry — ISO 9001:2015 Certified. Alfa Chemistry.
(+)-Myriocin (2S,3R,4R)-(E)-2-Amino-3,4-dihydroxy-2-hydroxymethyl- (+)-Myriocin (2S,3R,4R)-(E)-2-Amino-3,4-dihydroxy-2-hydroxymethyl-. Group: Biochemicals. Grades: Highly Purified. CAS No. 35891-70-4. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. Molecular Formula: C21H39NO6. US Biological Life Sciences. USBiological 5
Worldwide
Myriocin (Thermozymocidin, ISP) Myriocin is an a-amino fatty acid derived from species of several genera of fungi, notably Myriococcum, Melanconis and Isaria. Myriocin is a potent inhibitor of sphingosine biosynthesis by blocking the first enzyme in the pathway, serine palmitoyltransferase. Myriocin induces apoptosis by depletion of cellular sphingolipids, inhibits proliferation of IL-2-dependent mouse cytotoxic cells and is a potent immunosuppressant. Group: Biochemicals. Grades: Highly Purified. CAS No. 35891-70-4. Pack Sizes: 2.5mg. US Biological Life Sciences. USBiological 1
Worldwide

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