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| Product | Description | |
|---|---|---|
| CP-724714 | CP-724714 is An orally bioavailable quinazoline with potential antineoplastic activity. CP-724,714 selectively binds to the intracellular domain of HER2, reversibly inhibiting its tyrosine kinase activity and resulting in suppression of tumor cell growth. HER2, a member of the epidermal growth factor receptor (EGFR) family, is overexpressed in many adenocarcinomas, particularly breast cancers. Synonyms: CP-724714; CP 724714; CP724714. CAS No. 383432-38-0. Molecular formula: C27H27N5O3. Mole weight: 469.545. |  |
| CP-724714 | CP-724714 is a potent, selective and orally active ErbB2 (HER2) tyrosine kinase inhibitor, with an IC 50 of 10 nM. CP-724714 displays a marked selectivity against EGFR kinase (IC 50 =6400 nM). CP-724714 potently inhibits ErbB2 receptor autophosphorylation in intact cells. Antitumor activities [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 383432-38-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-14674. |  |
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