Find where to buy products from suppliers in the USA, including: distributors, industrial manufacturers in America, bulk supplies and wholesalers of raw ingredients & finished goods.
Search for products or services, then visit the American suppliers website for prices, SDS or more information. You can also view suppliers in Australia, NZ or the UK.
| Product | Description | |
|---|---|---|
| 4'-Demethylepipodophyllotoxin | 4'-Demethylepipodophyllotoxin(4'-DMEP) is a key intermediate compound for the preparation of podophyllotoxin-type anti-cancer drugs; a potent inhibitor of microtubule assembly.IC50 Value: 0.31uM(EC5 0in HL60 cell, MTT assay, 48h); 0.37uM(EC50 in HepG2 cell, MTT assay, 48h) Target: microtubulein vitro: 4-TMP-DMEP showed strong cytotoxicity activity against the above-mentioned five tumor cell lines. The EC50s of 4-TMP-DMEP against these tumor cell lines ranged from 0.24 to 0.11 μM, which were 0.29 to 3618 times lower than that of DMEP.in vivo: Treatment of animals with DMEP (until the end of the experiment), 30 min before TPA treatment, significantly reduced the tumor incidence, tumor volume and the conversion efficiency of papillomas to squamous cell carcinomas. The tumor formation and growth was also delayed by DMEP pre-treatment. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 4-Domethylpodophyllotoxin, 4'-demethyl-epi-podophyllotoxin. Product Category: Inhibitors. Appearance: Powder. CAS No. 6559-91-7. Molecular formula: C21H20O8. Mole weight: 400.38. Purity: 0.98. IUPACName: (5S,5aR,8aR,9R)-5-hydroxy-9-(4-hydroxy-3,5-dimethoxyphenyl)-5a,6,8a,9-tetrahydro-5H-[2]benzofuro[5,6-f][1,3]benzodioxol-8-one. Canonical SMILES: COC1=CC(=CC(=C1O)OC)[C@H]2[C@@H]3[C@H](COC3=O)[C@@H](C4=CC5=C(C=C24)OCO5)O. Density: 1.446±0.06 g/ml. Product ID: ACM6559917. Alfa Chemistry |  |
| 4'-Demethylepipodophyllotoxin | 4'-Demethylepipodophyllotoxin (4'-DMEP) is an intermediate compound that inhibits microtubule assembly. Uses: Scientific research. Group: Natural products. Alternative Names: 4'-O-demethylepipodophyllotoxin; 4'-DMEP. CAS No. 6559-91-7. Pack Sizes: 500 mg; 1 g. Product ID: HY-17435. |  |
| 4'-Demethylepipodophyllotoxin-4-(2,3-DI-O-Chloroacetyl-4,6-O-Ethylidene)-b-D-Glucopyranoside | 4'-Demethylepipodophyllotoxin-4-(2,3-DI-O-Chloroacetyl-4,6-O-Ethylidene)-b-D-Glucopyranoside. Product ID: 3-00301. |  |
| 4-Demethylepipodophyllotoxin | 4-Demethylepipodophyllotoxin - Product ID: NST-10-86. Category: Polyphenols. Purity: 98%. Test method: HPLC. CAS No. 6559-91-7. Pack Sizes: 5g, 10g, 25g, 50g. Appearance: White Powder. Molecular formula: C21H20O8. Mole weight: 400.38. Storage: +2 +8 °C. |  |
| Etoposide | Etoposide (VP-16; VP-16-213) is an anti-cancer chemotherapy agent. Etoposide inhibits topoisomerase II, thus stopping DNA replication. Etoposide induces cell cycle arrest, apoptosis and autophagy. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 4-Demethylepipodophyllotoxin-beta-d-ethylideneglucoside. Product Category: Inhibitors. Appearance: Powder. CAS No. 33419-42-0. Molecular formula: C29H32O13. Mole weight: 588.56. Purity: 0.98. IUPACName: (5S,5aR,8aR,9R)-5-[[(2R,4aR,6R,7R,8R,8aS)-7,8-dihydroxy-2-methyl-4,4a,6,7,8,8a-hexahydropyrano[3,2-d][1,3]dioxin-6-yl]oxy]-9-(4-hydroxy-3,5-dimethoxyphenyl)-5a,6,8a,9-tetrahydro-5H-[2]benzofuro[6,5-f][1,3]benzodioxol-8-one. Canonical SMILES: CC1OCC2C(O1)C(C(C(O2)OC3C4COC(=O)C4C(C5=CC6=C(C=C35)OCO6)C7=CC(=C(C(=C7)OC)O)OC)O)O. Density: 1.29 g/ml. Product ID: ACM33419420. Alfa Chemistry ISO 9001:2015 Certified. | |
| 4'Demethyl epipodophyllotoxin | 4'-DMEP. inhibitor of microtubule assembly. CAS No. 6559-91-7. Product ID: 1-01474. Molecular formula: C21H20O8. Mole weight: 400.39. Purity: contains approximately 5% residual H2O and CH3OH. Categories: 4' Demethylepipodophyllotoxin. | |
Our database is helping our users find suppliers everyday.
