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1-(4-methoxyphenyl)-6-(4-(2-methyl-6-oxopiperidin-1-yl)phenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide is an impurity of Apixaban, a direct factor Xa inhibitor used as an anticoagulant for the prevention of venous thromboembolism and stroke in atrial fibrillation. Synonyms: 1-(4-Methoxyphenyl)-6-[4-(2-methyl-6-oxo-1-piperidinyl)phenyl]-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide; 1-(4-Methoxyphenyl)?-6-(4-(2-methyl-6-oxopiperidin-1-yl)?phenyl)?-7-oxo-4,?5,?6,?7-tetrahydro-1H-pyrazolo[3,?4-c]?pyridine-3-carboxamide. CAS No. 2098457-92-0. Molecular formula: C26H27N5O4. Mole weight: 473.52.
1-(4-Methoxyphenyl)-6-(4-nitrophenyl)-7-oxo-6,7-dihydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylic Acid Ethyl Ester is a derivative of Apixaban (A726700), a potent, direct, selective, and orally active inhibitor of coagulation factor Xa. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg, 25mg. Molecular Formula: C22H18N4O6, Molecular Weight: 434.4. US Biological Life Sciences.
1-(4-Methoxyphenyl)-7-oxo-6-[4-(2-oxopiperidin-1-yl)phenyl]-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylic Acid is an intermediate of the synthesis of Apixaban (A726700) which is an inhibitor of blood coagulation factor Xa. Group: Biochemicals. Grades: Highly Purified. CAS No. 503614-92-4. Pack Sizes: 2.5mg, 5mg. Molecular Formula: C25H24N4O5, Molecular Weight: 460.48. US Biological Life Sciences.
1-(4-Methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-6,7-dihydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylic Acid is a derivative of Apixaban (A726700), a potent, direct, selective, and orally active inhibitor of coagulation factor Xa. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2.5mg, 5mg. Molecular Formula: C25H22N4O5, Molecular Weight: 458.47. US Biological Life Sciences.
1-(4-Methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-6,7-dihydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylic Acid Ethyl Ester is a derivative of Apixaban (A726700), a potent, direct, selective, and orally active inhibitor of coagulation factor Xa. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2.5mg, 5mg. Molecular Formula: C27H26N4O5, Molecular Weight: 486.52. US Biological Life Sciences.
2- (4-Methoxyphenyl) imidazo[1, 2-a]pyridine-3-carbaldehyde. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 250mg, 1g, 5g. US Biological Life Sciences.
Worldwide
2-(4-Methoxyphenyl)pyridine
2-(4-Methoxyphenyl)pyridine. Group: Ligands for functional metal complexes. Alternative Names: 2-(4-METHOXYPHENYL)PYRIDINE; AKOS BAR-0496. CAS No. 5957-90-4. Product ID: 2-(4-methoxyphenyl)pyridine. Molecular formula: 185.22g/mol. Mole weight: C12H11NO. COC1=CC=C(C=C1)C2=CC=CC=N2. InChI=1S/C12H11NO/c1-14-11-7-5-10 (6-8-11)12-4-2-3-9-13-12/h2-9H, 1H3. QUMXRZNAUFKBAS-UHFFFAOYSA-N.
3-Bromo-5-(4-methoxyphenyl)pyridine
3-Bromo-5-(4-methoxyphenyl)pyridine. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 3-BROMO-5-(4-METHOXYPHENYL)PYRIDINE. Product Category: Heterocyclic Organic Compound. CAS No. 452972-07-5. Molecular formula: C12H10BrNO. Product ID: ACM452972075. Alfa Chemistry ISO 9001:2015 Certified.
4-(4-Methoxyphenyl)-4,5,6,7-tetrahydrothieno[3,2-c]pyridine. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 4-(4-METHOXYPHENYL)-4,5,6,7-TETRAHYDROTHIENO[3,2-C]PYRIDINE;methyl 4-(4,5,6,7-tetrahydrothieno[3,2-c]pyridin-4-yl)phenyl ether. Product Category: Heterocyclic Organic Compound. CAS No. 213462-19-2. Molecular formula: C14H15NOS. Mole weight: 245.34. Product ID: ACM213462192. Alfa Chemistry ISO 9001:2015 Certified.
6-(4-((5-amino-5-oxopentyl)amino)phenyl)-1-(4-methoxyphenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide is a metabolite of Apixaban, a direct factor Xa inhibitor used as an anticoagulant for the prevention of venous thromboembolism and stroke in atrial fibrillation. Synonyms: 6-{4-[(5-Amino-5-oxopentyl)amino]phenyl}-1-(4-methoxyphenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide; Des(2-oxo-1-piperidinyl)6-(4-(5-Amino-5-oxopentyl))Apixaban. CAS No. 2187409-01-2. Molecular formula: C25H28N6O4. Mole weight: 476.53.
6-(4-Methoxyphenyl)pyridine-2-carboxylic acid
6-(4-Methoxyphenyl)pyridine-2-carboxylic acid. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 6-(4-Methoxyphenyl)pyridine-2-carboxylic acid. Product Category: Heterocyclic Organic Compound. CAS No. 86696-70-0. Molecular formula: C13H11NO3. Mole weight: 229.234. Purity: 0.96. IUPACName: 6-(4-methoxyphenyl)pyridine-2-carboxylic acid. Canonical SMILES: COC1=CC=C(C=C1)C2=NC(=CC=C2)C(=O)O. Product ID: ACM86696700. Alfa Chemistry ISO 9001:2015 Certified.
An impurity of Apixaban, a direct factor Xa inhibitor used as an anticoagulant for the prevention of venous thromboembolism and stroke in atrial fibrillation. CAS No. 1619934-76-7. Molecular formula: C31H37N5O6. Mole weight: 575.7.
2-(4-Methoxy-phenyl)-4-methyl-pyridine
2-(4-Methoxy-phenyl)-4-methyl-pyridine. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 2-(4-METHOXY-PHENYL)-4-METHYL-PYRIDINE. Product Category: Heterocyclic Organic Compound. CAS No. 80636-01-7. Molecular formula: C13H13NO. Mole weight: 199.24842. Product ID: ACM80636017. Alfa Chemistry ISO 9001:2015 Certified. Categories: 2-(4-Methoxyphenyl)-4-methylpyridine.
3- (4-Methoxyphenyl) benzaldehyde
3- (4-Methoxyphenyl) benzaldehyde is a reagent used in the preparation of pyridine-pyrazole N-N ligand, an effective catalyst for Suzuki coupling reactions. Group: Biochemicals. Grades: Highly Purified. CAS No. 118350-17-7. Pack Sizes: 250mg, 1g. Molecular Formula: C14H12O2, Molecular Weight: 212.24. US Biological Life Sciences.
4,6-Diamino-1-(4-methoxy-phenyl)-2-oxo-2,3-dihydro-1H-pyrrolo[2,3-b]pyridine-5-carbonitrile. Uses: Designed for use in research and industrial production. Additional or Alternative Names: ZINC03885583, CID7062703, 124476-83-1. Product Category: Heterocyclic Organic Compound. CAS No. 124476-83-1. Molecular formula: C15H13N5O2. Mole weight: 295.295. Purity: 0.96. IUPACName: 4,6-diamino-1-(4-methoxyphenyl)-2-oxo-3H-pyrrolo[2,3-b]pyridin-7-ium-5-carbonitrile. Canonical SMILES: COC1=CC=C(C=C1)N2C(=O)CC3=C2N=C(C(=C3N)C#N)N. Density: 1.48g/cm³. Product ID: ACM124476831. Alfa Chemistry ISO 9001:2015 Certified.
(4-Methoxyphenyl)-pyridin-3-ylmethanone
(4-Methoxyphenyl)-pyridin-3-ylmethanone. Uses: Designed for use in research and industrial production. Additional or Alternative Names: p-Anisyl 3-pyridyl ketone, Ketone, p-anisyl 3-pyridyl, 3-(4-Methoxybenzoyl)pyridine, p-Methoxyphenyl 3-pyridyl ketone, Pyridine, 3-(4-methoxybenzoyl)-, CID32108, BRN 0153949, ZINC02014954, KETONE, (p-METHOXYPHENYL) 3-PYRIDYL, LS-87278, 5-21-12-00522 (Beilstein Handbook Reference), 23826-71-3. Product Category: Heterocyclic Organic Compound. CAS No. 23826-71-3. Molecular formula: C13H11NO2. Mole weight: 213.232 g/mol. Purity: 0.96. IUPACName: (4-methoxyphenyl)-pyridin-3-ylmethanone. Canonical SMILES: COC1=CC=C(C=C1)C(=O)C2=CN=CC=C2. Density: 1.154g/cm³. Product ID: ACM23826713. Alfa Chemistry ISO 9001:2015 Certified.
5''''-Methyl-apixaban
5''''-Methyl-apixaban is an impurity of Apixaban, a direct factor Xa inhibitor used as an anticoagulant for the prevention of venous thromboembolism and stroke in atrial fibrillation. Synonyms: 1-(4-methoxyphenyl)-6-(4-(5-methyl-2-oxopiperidin-1-yl)phenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide; 1-(4-Methoxyphenyl)-6-[4-(5-methyl-2-oxo-1-piperidinyl)phenyl]-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide. CAS No. 1686149-74-5. Molecular formula: C26H27N5O4. Mole weight: 473.52.
6-Chloro-N-(4-methoxy-benzyl)-nicotinamide
6-Chloro-N-(4-methoxy-benzyl)-nicotinamide. Uses: Designed for use in research and industrial production. Additional or Alternative Names: AC1MARH8, CTK3E5459, AKOS000156007, AG-C-76687, 64810P, 6-chloro-N-[(4-methoxyphenyl)methyl]pyridine-3-carboxamide, 3-Pyridinecarboxamide, 6-chloro-N-[(4-methoxyphenyl)methyl]-, 805303-96-2. Product Category: Heterocyclic Organic Compound. CAS No. 805303-96-2. Molecular formula: C14H13ClN2O2. Mole weight: 276.718220 [g/mol]. Purity: 0.96. IUPACName: 6-chloro-N-[(4-methoxyphenyl)methyl]pyridine-3-carboxamide. Product ID: ACM805303962. Alfa Chemistry ISO 9001:2015 Certified.
Apixaban Acid
A metabolite of Apixaban, a direct factor Xa inhibitor used as an anticoagulant for the prevention of venous thromboembolism and stroke in atrial fibrillation. Synonyms: 1-(4-Methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylic acid; Apixaban Impurity 41. CAS No. 503614-92-4. Molecular formula: C25H24N4O5. Mole weight: 460.5.
Apixaban Dehydro Impurity
A metabolite of Apixaban, a direct factor Xa inhibitor used as an anticoagulant for the prevention of venous thromboembolism and stroke in atrial fibrillation. Synonyms: 4,5-Dehydro Apixaban; 1-(4-Methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-6,7-dihydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide; 6,7-Dihydro-1-(4-methoxyphenyl)-7-oxo-6-[4-(2-oxo-1-piperidinyl)phenyl]-1H-Pyrazolo[3,4-c]pyridine-3-carboxamide. Grades: > 95%. CAS No. 1074549-89-5. Molecular formula: C25H23N5O4. Mole weight: 457.49.
Apixaban Impurity 106
Apixaban Impurity 106. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 6-(4-aminophenyl)-1-(4-methoxyphenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylic acid. CAS No. 1704504-93-7. Molecular formula: C20H18N4O4. Mole weight: 378.38. Catalog: APB1704504937.
Apixaban Impurity 14
A metabolite of Apixaban. Synonyms: 6-(4-Aminophenyl)-4,5,6,7-tetrahydro-1-(4-methoxyphenyl)-7-oxo-1H-pyrazolo[3,4-c]pyridine-3-carboxylic Acid. Grades: > 95%. CAS No. 1704504-93-7. Molecular formula: C20H18N4O4. Mole weight: 378.39.
Apixaban Impurity 15
A metabolite of Apixaban. Synonyms: 6-(4-Aminophenyl)-4,5,6,7-tetrahydro-1-(4-methoxyphenyl)-7-oxo-1H-pyrazolo[3,4-c]pyridine-3-carboxylic Acid Methyl Ester. Grades: > 95%. CAS No. 1466571-07-2. Molecular formula: C21H20N4O4. Mole weight: 392.42.
Apixaban Impurity 9
A metabolite of Apixaban. Synonyms: Apixaban V; 1-(4-Methoxyphenyl)-7-oxo-6-[4-(2-oxopiperidin-1-yl)phenyl]-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylic Acid Ethyl Ester Ethyl 1-(4-Methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyri. Grades: > 95%. CAS No. 503614-91-3. Molecular formula: C27H28N4O5. Mole weight: 488.55.
Apixaban Impurity BMS-728626-01
Apixaban Impurity BMS-728626-01. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 1-(4-methoxyphenyl)-6-(4-(5-methyl-2-oxopiperidin-1-yl)phenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide. CAS No. 1686149-74-5. Molecular formula: C26H27N5O4. Mole weight: 473.52. Catalog: APB1686149745.
Apixaban Impurity D
Apixaban Impurity D. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: methyl 1-(4-methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate. CAS No. 1074365-84-6. Molecular formula: C26H26N4O5. Mole weight: 474.51. Catalog: APB1074365846.
Apixaban Impurity H
Apixaban Impurity H. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 1-(4-methoxyphenyl)-7-oxo-6-(4-(2-oxoazepan-1-yl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide. CAS No. 1074549-87-3. Molecular formula: C26H27N5O4. Mole weight: 473.52. Catalog: APB1074549873.
Apixaban Impurity TQ
Apixaban Impurity TQ. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 1-(4-methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-6,7-dihydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide. CAS No. 1074549-89-5. Molecular formula: C25H23N5O4. Mole weight: 457.48. Catalog: APB1074549895.
Blonanserin Impurity 21
Blonanserin Impurity 21. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 2-(4-ethylpiperazin-1-yl)-4-(4-methoxyphenyl)-5,6,7,8,9,10-hexahydrocycloocta[b]pyridine. CAS No. 132810-93-6. Molecular formula: C24H33N3O. Mole weight: 379.54. Catalog: APB132810936.
HMN-176
HMN-176 is an active metabolite of the synthetic antitumor compound HMN-214. HMN-176 shows potent cytotoxicity toward various human tumor cell lines, and in mitotic cells, it causes cell cycle arrest at M phase through the destruction of spindle polar bodies, followed by the induction of DNA fragmentation. However, no direct interactions of HMN-176 with tubulin are observed. Moreover, in animal models, it was observed that oral administration of the prodrug HMN-214 caused no significant nerve toxicity, a severe side effect often associated with microtubule binding agents such as Taxol and VCR.3 In Phase I clinical trials, HMN-214 has caused sensory neuropathy and ileus in some patients. However, the grade and frequency of these adverse effects were much lower than those of typical microtubule binding agents. As expected from the mechanism of action of HMN-214 (induction of G2-M arrest in dividing cells), the main adverse effect was neutropenia. (Source: CANCER RESEARCH 63, 6942 -6947). Uses: Designed for use in research and industrial production. Additional or Alternative Names: HMN176; HMN 176; HMN-176. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 173529-10-7. Molecular formula: C20H18N2O4S. Mole weight: 382.43. Purity: >98%. IUPACName: (E)-4-(2-(4-methoxyphenylsulfonamido)styryl)pyridine 1-oxide. Canonical SMILES: O=S(NC1=CC=CC=C1/C=C/C2=CC=[N+]([O-])C=C2)(C3=CC=C(OC)C=C3)=O. Product ID: ACM173529107. Alfa Ch
N-Formyl Apixaban
N-Formyl Apixaban is an impurity of Apixaban, a direct factor Xa inhibitor used as an anticoagulant for the prevention of venous thromboembolism and stroke in atrial fibrillation. Synonyms: N-formyl-1-(4-methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide; 1H-Pyrazolo[3,4-c]pyridine-3-carboxamide, N-formyl-4,5,6,7-tetrahydro-1-(4-methoxyphenyl)-7-oxo-6-[4-(2-oxo-1-piperidinyl)phenyl]-. CAS No. 1351611-14-7. Molecular formula: C26H25N5O5. Mole weight: 487.5.
SB 202474
SB 202474 is an analog of SB 202190 and SB 203580, which are inhibitors of the MAP kinases p38α and p38&beta. SB 202474 has been used as a negative control in studies of p38 inhibition. Synonyms: SB-202474; SB202474; 4-[5-ethyl-2-(4-methoxyphenyl)-1H-imidazol-4-yl]pyridine. Grades: ≥97%. CAS No. 172747-50-1. Molecular formula: C17H17N3O. Mole weight: 279.3.
1-[2-(4-Isothiocyatophenoxy)ethyl]-4-[5-(4-methoxyphenyl)-2-oxazolyl] pyridin. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 1-[2-(4-Isothiocyatophenoxy)ethyl]-4-[5-(4-methoxyphenyl)-2-oxazolyl]pyridinium tosylate. Product Category: Other Fluorophores. Appearance: Solid. CAS No. 155862-93-4. Molecular formula: C31H27N3O6S2. Mole weight: 601.69. Purity: 95%+. Product ID: ACM155862934-1. Alfa Chemistry ISO 9001:2015 Certified. Categories: 1-[2-(4-Isothiocyanatophenoxy)ethyl]-4-[5-(4-methoxyphenyl)-2-oxazolyl]pyridinium tosylate.
1-(2-Isothiocyatoethyl)-4-[5-(4-methoxyphenyl)-2-oxazolyl]pyridinium bromide. Uses: Designed for use in research and industrial production. Product Category: Other Fluorophores. Appearance: Yellow solid. CAS No. 155862-91-2. Molecular formula: C18H16BrN3O2S. Mole weight: 418.31. Purity: 90%+. Product ID: ACM155862912-1. Alfa Chemistry ISO 9001:2015 Certified.
1-[2-(Maleimido)ethyl]-4-[5-(4-methoxyphenyl)-2-oxazolyl] pyridinium triflate. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 1-(2-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)ethyl)-4-(5-(4-methoxyphenyl)oxazol-2-yl)pyridin-1-ium trifluoromethanesulfote. Product Category: Other Fluorophores. Appearance: Solid. CAS No. 155862-98-9. Molecular formula: C22H18F3N3O7S. Mole weight: 525.46. Purity: 90%+. Product ID: ACM155862989-1. Alfa Chemistry ISO 9001:2015 Certified. Categories: 1-[2-(Maleimido)ethyl]-4-[5-(4-methoxyphenyl)-2-oxazolyl]pyridinium triflate.
Used in the preparation of PhIP (A617000) metabolites and derivatives. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences.
1-(3-Isothiocyanatopropyl)-4-[5-(4-methoxyphenyl)-2-oxazolyl]pyridinium bromide is a fluorescent reagent with high selectivity. Group: Biochemicals. Grades: Highly Purified. CAS No. 1034443-41-8. Pack Sizes: 5mg, 10mg. Molecular Formula: C19H18N3O2S Br, Molecular Weight: 352.43799. US Biological Life Sciences.
1-(4-Methoxybenzyl)-3-hydroxy-4-ethoxycarbonyl-5-(3-pyridyl)-3-pyrrolin-2-one. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 2,5-Dihydro-4-hydroxy-1-[(4-methoxyphenyl)methyl]-5-oxo-2-(3-pyridinyl)-1H-pyrrole-3-carboxylic Acid Ethyl Ester. Product Category: Heterocyclic Organic Compound. Appearance: White Solid. CAS No. 359436-85-4. Molecular formula: C20H20N2O5. Mole weight: 368.38. Purity: 0.96. IUPACName: ethyl 4-hydroxy-1-[(4-methoxyphenyl)methyl]-5-oxo-2-pyridin-3-yl-2H-pyrrole-3-carboxylate. Canonical SMILES: CCOC(=O)C1=C(C(=O)N(C1C2=CN=CC=C2)CC3=CC=C(C=C3)OC)O. Density: 1.332g/cm³. Product ID: ACM359436854. Alfa Chemistry ISO 9001:2015 Certified.
1-(4-Methoxyphenyl)pyridin-2(1H)-one
1-(4-Methoxyphenyl)pyridin-2(1H)-one. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 25mg. US Biological Life Sciences.
Used in the preparation of PhIP (A617000) metabolites and derivatives. Group: Biochemicals. Alternative Names: N3-Methyl-5-(4-methoxyphenyl)-2,3-pyridinediamine. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
3,5-Didemethoxy Piperlongumine
3,5-Didemethoxy Piperlongumine. Group: Biochemicals. Alternative Names: 5,6-Dihydro-1-[3-(4-methoxyphenyl)-1-oxo-2-propen-1-yl]-2(1H)-pyridinone. Grades: Highly Purified. CAS No. 1246095-66-8. Pack Sizes: 50mg. Molecular Formula: C15H15NO3, Molecular Weight: 257.279999999999. US Biological Life Sciences.
Worldwide
3-Bromo-5-(4-methoxyphenyl)-2-pyridinamine
Used in the preparation of PhIP (A617000) metabolites and derivatives. Group: Biochemicals. Grades: Highly Purified. CAS No. 1381938-33-5. Pack Sizes: 50mg. US Biological Life Sciences.
Worldwide
3-Deaza-3-methyl-dA CEP
3-Deaza-3-methyl-dA CEP, a pivotal compound within the biomedicine realm, boasts indispensability. Its principal application resides in the amalgamation of DNA analogs and the adjustment of nucleosides, serving as a catalyst for cutting-edge investigations. By assuming a critical role in anti-viral drug development and genetic disease analysis, this product furnishes invaluable perspectives on diverse therapeutic interventions. Synonyms: Benzamide, N-benzoyl-N-[1-[5-O-[bis(4-methoxyphenyl)phenylmethyl]-3-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-2-deoxy-beta-D-erythro-pentofuranosyl]-7-methyl-1H-imidazo[4,5-c]pyridin-4-yl]-; DTXSID001098448; N-Benzoyl-N-[1-[5-O-[bis(4-methoxyphenyl)phenylmethyl]-3-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-2-deoxy-beta-D-erythro-pentofuranosyl]-7-methyl-1H-imidazo[4,5-c]pyridin-4-yl]benzamide. CAS No. 1031750-37-4. Molecular formula: C56H59N6O8P. Mole weight: 975.08.
5-(4-Methoxyphenyl)-2-pyridinamine
Used in the preparation of luciferase inhibitors, substituted triazoles as antifungal agents and PhIP (A617000) metabolites and derivatives. Group: Biochemicals. Grades: Highly Purified. CAS No. 503536-75-2. Pack Sizes: 100mg. US Biological Life Sciences.
6-(4-Methoxyphenyl)-5-methyl-3-(4-pyridinyl)-isoxazolo[4,5-c]pyridin-4(5H)-one hydrochloride. Uses: Designed for use in research and industrial production. Additional or Alternative Names: S14-1930; Thioperamide; 6-(4-Methoxyphenyl)-5-methyl-3-(4-pyridinyl)-isoxazolo[ 4,5-c]pyridin-4(5H)-one. Product Category: Heterocyclic Organic Compound. CAS No. 479077-02-6. Molecular formula: 369.8. Purity: >98 %. IUPACName: 6-(4-methoxyphenyl)-5-methyl-3-pyridin-4-yl-[1,2]oxazolo[4,5-c]pyridin-4-one. Canonical SMILES: CN1C(=CC2=C(C1=O)C(=NO2)C3=CC=NC=C3)C4=CC=C(C=C4)OC. Product ID: ACM479077026. Alfa Chemistry ISO 9001:2015 Certified. Categories: mmpip hydrochloride.
AVE-0118
AVE 0118 is a potassium channel blocker that has the potential for the treatment of sleep apnea syndrome. AVE 0118 functions without apparent effect on ventricular repolarization. Noteworthy, the atrial selective and dose-dependent prolongation of atrial refractoriness (ERP) by AVE 0118 has been claimed to be an inhibitory effect of sodium channel activity in an atrial-selective manner, and may therefore contribute to the anti-AF property of AVE0118. Synonyms: [1,1'-Biphenyl]-2-carboxamide, 2'-[[[2-(4-methoxyphenyl)acetyl]amino]methyl]-N-[2-(3-pyridinyl)ethyl]-; 2'-[[[2-(4-Methoxyphenyl)acetyl]amino]methyl]-N-[2-(3-pyridinyl)ethyl][1,1'-biphenyl]-2-carboxamide; [1,1'-Biphenyl]-2-carboxamide, 2'-[[[(4-methoxyphenyl)acetyl]amino]methyl]-N-[2-(3-pyridinyl)ethyl]-; 2'-[[2- (4-Methoxyphenyl) acetylamino]methyl]biphenyl-2-carboxylic acid (2-pyridin-3-yl-ethyl)amide; AVE 0118; AVE0118. Grades: ≥95%. CAS No. 498577-53-0. Molecular formula: C30H29N3O3. Mole weight: 479.57.
AVE 0118 hydrochloride
AVE 0118 hydrochloride is a potassium channel blocker that has the potential for the treatment of sleep apnea syndrome. AVE 0118 functions without apparent effect on ventricular repolarization. Noteworthy, the atrial selective and dose-dependent prolongation of atrial refractoriness (ERP) by AVE 0118 has been claimed to be an inhibitory effect of sodium channel activity in an atrial-selective manner, and may therefore contribute to anti-AF property of AVE0118. Synonyms: Benzeneacetamide, 4-methoxy-N-[[2'-[[[2-(3-pyridinyl)ethyl]amino]carbonyl][1,1'-biphenyl]-2-yl]methyl]-, hydrochloride (1:1); 2'-[[[2-(4-Methoxyphenyl)acetyl]amino]methyl]-N-[2-(3-pyridinyl)ethyl][1,1'-biphenyl]-2-carboxamide hydrochloride; [1,1'-Biphenyl]-2-carboxamide, 2'-[[[(4-methoxyphenyl)acetyl]amino]methyl]-N-[2-(3-pyridinyl)ethyl]-, hydrochloride; 2'-[[2- (4-Methoxyphenyl) acetylamino]methyl]biphenyl-2-carboxylic acid (2-pyridin-3-yl-ethyl)amide hydrochloride; AVE 0118 hydrochloride; AVE0118 hydrochloride. Grades: 99%. CAS No. 2108821-80-1. Molecular formula: C30H29N3O3.HCl. Mole weight: 516.03.
c-(4-Methoxy-phenyl)-c-pyridin-4-yl-methylamine dihydrochloride. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 889939-88-2, Ambcb4003415, CTK8E0959, MolPort-003-991-669, AKOS015845711, C-(4-Methoxyphenyl)-C-pyridin-4-yl, I05-1666, (4-methoxyphenyl)(pyridin-4-yl)methanamine dihydrochloride, C-(4-Methoxyphenyl)-C-pyridin-4-yl methylamine dihydrochloride, c-(4-methoxy-phenyl)-c-pyridin-4-yl-methylamine dihydrochloride. Product Category: Heterocyclic Organic Compound. CAS No. 889939-88-2. Molecular formula: C13H16Cl2N2O. Mole weight: 287.19. Purity: 0.96. IUPACName: (4-methoxyphenyl)-pyridin-4-ylmethanamine;dihydrochloride. Canonical SMILES: COC1=CC=C(C=C1)C(C2=CC=NC=C2)N.Cl.Cl. Density: 1.124g/cm³. Product ID: ACM889939882. Alfa Chemistry ISO 9001:2015 Certified.
CGS20625
CGS-20625 is an anxiolytic drug used in scientific research. It has similar effects to benzodiazepine drugs, but is structurally distinct and so is classed as a nonbenzodiazepine anxiolytic. It produces anxiolytic and anticonvulsant effects, but with no sedative effects even at high doses, and no significant muscle relaxant effects. It is orally active in humans, but with relatively low bioavailability. CGS-20625 is a positive allosteric modulator at several GABAA receptors types. Due to its alicyclic moiety potency at γ1 subunit, containing receptor types is more pronounced for CGS-20625 compared to benzodiazepines. γ1 subunits are expressed at higher levels in the central amygdala. Uses: Designed for use in research and industrial production. Additional or Alternative Names: CGS20625; CGS-20625; CGS 20625. Product Category: Others. Appearance: Solid powder. CAS No. 111205-55-1. Molecular formula: C18H19N3O2. Mole weight: 309.37. Purity: >98%. IUPACName: Cyclohepta(b)pyrazolo(3,4-d)pyridin-3(2H)-one, 5,6,7,8,9,10-hexahydro-2-(4-methoxyphenyl)-. Canonical SMILES: O=C1N(C2=CC=C(OC)C=C2)N=C3C(CCCCC4)=C4NC=C31. Product ID: ACM111205551-1. Alfa Chemistry ISO 9001:2015 Certified.
CGS 20625
CGS 20625 is a partial agonist for the benzodiazepine binding site of the GABAA receptor used as an anti-anxiety drug. It acts as a central benzodiazepine receptor agonist (IC50 = 1.3 nM) with no affinity for other neurotransmitter receptor binding sites. Uses: Anti-anxiety drug. Synonyms: CGS 20625; CGS20625; CGS-20625; 5, 6, 7, 8, 9, 10-Hexahydro-2- (4-methoxyphenyl) cyclohepta[b]pyrazolo[3, 4-d]pyridin-3 (2H) -one. Grades: ≥99% by HPLC. CAS No. 111205-55-1. Molecular formula: C18H19N3O2. Mole weight: 309.36.
Chembrdg-bb 5530977
Chembrdg-bb 5530977. Uses: Designed for use in research and industrial production. Additional or Alternative Names: CHEMBRDG-BB 5530977;2-(4-METHOXYPHENYL)-N-(PYRIDIN-3-YLMETHYL)ETHANAMINE;N-(2-(4-METHOXYPHENYL)ETHYL)-N-(PYRIDIN-3-YLMETHYL)AMINE;UKRORGSYN-BB BBV-125777. Product Category: Heterocyclic Organic Compound. CAS No. 331970-95-7. Molecular formula: C15H18N2O. Mole weight: 242.32. Product ID: ACM331970957. Alfa Chemistry ISO 9001:2015 Certified.
MMPIP
MMPIP hydrochloride is a potent, selective, allosteric antagonist of metabotropic glutamate receptor 7 (mGluR7). It inhibits agonist-induced intracellular calcium mobilization and cAMP accumulation (IC50 = 26 and 610 nM). MMPIP also exhibits intrinsic activity and acts as an inverse agonist. Synonyms: 6-(4-Methoxyphenyl)-5-methyl-3-(4-pyridinyl)-isoxazolo[4,5-c]pyridin-4(5H)-one hydrochloride. Grades: ≥98% by HPLC. CAS No. 479077-02-6. Molecular formula: C19H15N3O3. Mole weight: 333.3.
A potent negative allosteric modulator highly selective for mGlu7 receptors (IC50 = 15nM). No effect on other subtype mGlu receptors. Frequently used in studies of alcohol and cocaine addition, depression, anxiety and stress related disorders. Group: Biochemicals. Grades: Highly Purified. CAS No. 479077-02-6. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
MMPIP hydrochloride
MMPIP is a reversible allosteric antagonist of the metabotropic glutamate receptor 7 (mGluR7) that blocks agonist-induced calcium mobilization (IC50 = 26 nM). It was demonstrated to reduce pain responses and affective/cognitive impairments in neuropathic pain conditions. Synonyms: 6-(4-Methoxyphenyl)-5-methyl-3-(4-pyridinyl)-isoxazolo[4,5-C]pyridin-4(5H)-one hydrochloride. Grades: ≥98%. CAS No. 1215566-78-1. Molecular formula: C19H15N3O3·HCl. Mole weight: 369.8.
MPT0B098
MPT0B098 is a potent microtubule inhibitor through binding to the colchicine-binding site of tubulin. MPT0B098 is active against the growth of various human cancer cells, including chemoresistant cells with IC50 values ranging from 70 to 150 nmol/L. MPT0B098 arrests cells in the G2-M phase and subsequently induces cell apoptosis. In addition, MPT0B098 effectively suppresses VEGF-induced cell migration and capillary-like tube formation of HUVECs. Distinguished from other microtubule inhibitors, MPT0B098 not only inhibited the expression levels of HIF-1α protein but also destabilized HIF-1α mRNA. The mechanism of causing unstable of HIF-1α mRNA by MPT0B098 is through decreasing RNA-binding protein, HuR, translocation from the nucleus to the cytoplasm. Notably, MPT0B098 effectively suppresses tumor growth and microvessel density of tumor specimens in vivo. Taken together, our results provide a novel mechanism of inhibiting HIF-1α of a microtubule inhibitor MPT0B098. MPT0B098 is a promising anticancer drug candidate with potential for the treatment of human malignancies. Synonyms: MPT 0B098; MPT-0B098; 1-(4-methoxyphenylsulfonyl)-7-(pyridin-4-yl)indoline. CAS No. 1254363-89-7. Molecular formula: C20H18N2O3S. Mole weight: 366.43.
N-(3-Isothiocyatobenzyl)-4-[5-(4-methoxyphenyl)-2-oxazolyl]pyridinium bromide. Uses: Designed for use in research and industrial production. Product Category: Other Fluorophores. Appearance: Solid. CAS No. 155862-89-8. Molecular formula: C23H18BrN3O2S. Mole weight: 480.38. Purity: 99%+. Product ID: ACM155862898-1. Alfa Chemistry ISO 9001:2015 Certified.
N-(3-Isothiocyatopropyl)-4-(5'-(4"-methoxyphenyl)-2'-oxazolyl) pyridinium bro. Uses: Designed for use in research and industrial production. Product Category: Other Fluorophores. Appearance: Solid. CAS No. 1034443-41-8. Molecular formula: C19H18BrN3O2S. Mole weight: 432.33. Purity: 90%+. Product ID: ACM1034443418. Alfa Chemistry ISO 9001:2015 Certified.
N-(3-Succinimidyloxy-carbonyl-phenyl)-methyl-4-(5'-(4"-methoxy-phenyl)-2'-oxazo. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Stain 7-I , N-(3-Succinimidyloxy-carbonyl-phenyl)-methyl-4-(5'-(4''-methoxy-phenyl)-2'-oxazolyl)-pyridinium bromide. Product Category: Other Fluorophores. Appearance: Yellow powder. CAS No. 155862-95-6. Molecular formula: C27H22BrN3O6. Mole weight: 564.38. Purity: 95%+. Product ID: ACM155862956-1. Alfa Chemistry ISO 9001:2015 Certified. Categories: 1-[3-(Succinimidyloxycarbonyl)benzyl]-4-[5-(4-methoxyphenyl)-2-oxazolyl]pyridinium bromide.
N'-(4-Cyanobutyl)-N-(4-methoxybenzyl)-N'-methyl-N-2-pyridinyl-1,2-ethanediamine. Uses: Designed for use in research and industrial production. Additional or Alternative Names: N'-(4-CYANOBUTYL)-N-(4-METHOXYBENZYL)-N'-METHYL-N-2-PYRIDINYL-1,2-ETHANEDIAMINE. Product Category: Heterocyclic Organic Compound. Appearance: Pale Yellow Oil. CAS No. 109912-34-7. Molecular formula: C21H28N4O. Mole weight: 352.47. Purity: 0.96. IUPACName: 5-[2-[(4-methoxyphenyl)methyl-pyridin-2-ylamino]ethyl-methylamino]pentanenitrile. Canonical SMILES: CN(CCCCC#N)CCN(CC1=CC=C(C=C1)OC)C2=CC=CC=N2. Density: 1.096g/cm³. Product ID: ACM109912347. Alfa Chemistry ISO 9001:2015 Certified.
N-(4-Isothiocyatobenzyl)-4-[5-(4-methoxyphenyl)-2-oxazolyl]pyridinium bromide. Uses: Designed for use in research and industrial production. Product Category: Other Fluorophores. Appearance: Orange powder. CAS No. 155862-90-1. Molecular formula: C23H18BrN3O2. Mole weight: 480.38. Purity: 98%+. Product ID: ACM155862901-1. Alfa Chemistry ISO 9001:2015 Certified.
N-(4-Methoxybenzyl)cotinine
N-(4-Methoxybenzyl)cotinine. Uses: Designed for use in research and industrial production. Additional or Alternative Names: N-(4-METHOXYBENZYL)COTININE. Product Category: Heterocyclic Organic Compound. Appearance: Low-Melting Yellow Solid. CAS No. 887406-85-1. Molecular formula: C17H18N2O2. Mole weight: 282.34. Purity: 0.96. IUPACName: 1-[(4-methoxyphenyl)methyl]-5-pyridin-3-ylpyrrolidin-2-one. Canonical SMILES: COC1=CC=C(C=C1)CN2C(CCC2=O)C3=CN=CC=C3. Density: 1.196g/cm³. Product ID: ACM887406851. Alfa Chemistry ISO 9001:2015 Certified.
N'-(5-Aminopentyl)-N-(4-methoxybenzyl)-N'-methyl-N-2-pyridinyl-1,2-ethanediamine, dimaleate salt
N'-(5-Aminopentyl)-N-(4-methoxybenzyl)-N'-methyl-N-2-pyridinyl-1,2-ethanediamine, dimaleate salt. Group: Biochemicals. Alternative Names: N-[2-[[(4-Methoxyphenyl)methyl]-2-pyridinylamino]ethyl]-N-methyl-1,5-pentanediamine (2Z)-2-butenedioate. Grades: Highly Purified. CAS No. 109912-42-7. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C29H40N4O9. US Biological Life Sciences.
Worldwide
N'-(5-Aminopentyl)-N-(4-methoxybenzyl)-N'-methyl-N-2-pyridinyl-1,2-ethanediamine,dimaleate salt
N'-(5-Aminopentyl)-N-(4-methoxybenzyl)-N'-methyl-N-2-pyridinyl-1,2-ethanediamine,dimaleate salt. Uses: Designed for use in research and industrial production. Additional or Alternative Names: N'-(5-AMINOPENTYL)-N-(4-METHOXYBENZYL)-N'-METHYL-N-2-PYRIDINYL-1,2-ETHANEDIAMINE, DIMALEATE SALT. Product Category: Heterocyclic Organic Compound. Appearance: White Crystalline Solid. CAS No. 109912-42-7. Molecular formula: C25H36N4O5. Mole weight: 472.58. Purity: 0.96. IUPACName: (Z)-but-2-enedioic acid;N-[2-[(4-methoxyphenyl)methyl-pyridin-2-ylamino]ethyl]-N-methylpentane-1,5-diamine. Canonical SMILES: CN(CCCCCN)CCN(CC1=CC=C(C=C1)OC)C2=CC=CC=N2.C(=CC(=O)O)C(=O)O.C(=CC(=O)O)C(=O)O. Product ID: ACM109912427. Alfa Chemistry ISO 9001:2015 Certified.
N'-Formyl-N-(4-methoxybenzyl)-N-(2-pyridinyl)-1,2-ethanediamine. Group: Biochemicals. Alternative Names: N- [2- [ [ (4-Methoxyphenyl) methyl] -2-pyridinylamino] ethyl] formamide. Grades: Highly Purified. CAS No. 109912-29-0. Pack Sizes: 25mg, 50mg, 100mg, 250mg, 500mg. Molecular Formula: C16H19N3O2. US Biological Life Sciences.
Worldwide
PC-046
PC-046 is a potent tubulin-binding agent, which was originally identified for development based on selective activity in deleted in pancreas cancer locus 4 (DPC4/SMAD4) deficient tumors. PC-046 has growth inhibitory activity in a variety of tumor types in vitro, and efficacy in SCID mice was shown in human tumor xenografts of MV-4-11 acute myeloid leukemia, MM.1S multiple myeloma, and DU-145 prostate cancer. Pharmacokinetic studies demonstrated relatively high oral bioavailability (71 %) with distribution to both plasma and bone marrow. No myelosuppression was seen in non-tumor bearing SCID mice given a single dose just under the acute lethal dose. The COMPARE algorithm in the NCI-60 cell line panel demonstrated that PC-046 closely correlated to other known tubulin destabilizing agents (correlation coefficients ?0.7 for vincristine and vinblastine). Mechanism of action studies showed cell cycle arrest in metaphase and inhibition of tubulin polymerization. Overall, these studies show that PC-046 is a synthetically-derived, small molecule microtubule destabilizing agent. Advantages over existing microtubule destabilizing agents include ease of synthesis, lack of MDR cross-resistance, good oral bioavailability and the lack of acute myelotoxicity. Synonyms: PC 046; PC046; NSC-756784; 5-(4-methoxyphenyl)-2-(3-(3-methoxyphenyl)pyridin-4-yl)oxazole. Grades: 98%. CAS No. 1202401-59-9. Molecular formula: C22H18N2O3. Mole weight: 358.39.
Pyrilamine maleate salt
Pyrilamine maleate salt is a first generation antihistamine and binds with high affinity to G(q/11) protein. It is commonly utilized as a radioligand binding assay for the H1 receptor. It also has anticholinergic properties. It is used in over-the-counter combination products to treat the common cold and menstrual symptoms. It is also the active ingredient of the topical antihistamine creams Anthisan and Neoantergan. It is also found to be a potent inhibitor of CYP2D6 in hepatocytes. It has been listed. Uses: Pyrilamine maleate salt is commonly utilized as a radioligand binding assay for the h1 receptor. it also has anticholinergic properties. it is used in over-the-counter combination products to treat the common cold and menstrual symptoms. Synonyms: N1-(4-Methoxybenzyl)-N2,N2-dimethyl-N1-(pyridin-2-yl)ethane-1,2-diamine fumarate;Diaminide maleate;(Z)-but-2-enedioic acid;N-[(4-Methoxyphenyl)methyl]-N',N'-dimethyl-N-2-pyridinyl- 1,2-ethanediamine (2Z)-2-Butenedioate;Paraminyl Maleate. Grades: 95%. CAS No. 59-33-6. Molecular formula: C21H27N3O5. Mole weight: 401.46.
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