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[2-(Di-tert-butylphosphinomethyl)-6-(diethylaminomethyl)pyridine]carbonylchlorohydridoruthenium(II). Uses: Ruthenium catalyst for the direct synthesis of amides from alcohols and primary amines. ruthenium catalyst for the hydrogenation of esters in high yields under mild pressure and neutral conditions. ruthenium catalyst for the dehydrogenative coupling of alcohols to form esters in high yields under neutral conditions. ruthenium catalyst for the synthesis of amides from esters and amines with liberation of hydrogen gas. ruthenium catalyst for the hydrogenation of 3-methyl-2-oxalidinone. Additional or Alternative Names: Carbonylchlorohydrido[6-(di-t-butylphosphinomethyl)-2-(N,N-diethylaminomethyl)pyridine]ruthenium(II);863971-62-4. Product Category: Ruthenium series catalysts. CAS No. 863971-62-4. Molecular formula: C20H37ClN2OPRu. Mole weight: 489.023g/mol. IUPACName: chlororuthenium;N-[[6-(ditert-butylphosphanylmethyl)pyridin-2-yl]methyl]-N-ethylethanamine;formaldehyde. Canonical SMILES: CCN(CC)CC1=NC(=CC=C1)CP(C(C)(C)C)C(C)(C)C.C=O.Cl[Ru]. Product ID: ACM863971624. Alfa Chemistry ISO 9001:2015 Certified. Categories: Milstein Catalyst Precursor.
[4-Anilino-4-oxo-3-(phenylcarbamoyl)butyl]-diethylazanium; hydrogensulfate. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Dethamid, Dethamide, 2-(2-(Diethylamino)ethyl)-N,N-diphenylpropanediamide monohydrochloride, Propanediamide, 2-(2-(diethylamino)ethyl)-N,N-diphenyl-, monohydrochloride, 52507-55-8, AC1L23NU, LS-119708, [4-anilino-4-oxo-3-(phenylcarbamoyl)butyl]-diethylazanium; hydrogen sulfate, N,N-diethyl-4-oxo-4-(phenylamino)-3-(phenylcarbamoyl)butan-1-aminium hydrogen sulfate. Product Category: Heterocyclic Organic Compound. CAS No. 52507-55-8. Molecular formula: C21H29N3O6S. Mole weight: 451.536 g/mol. Purity: 0.96. IUPACName: [4-anilino-4-oxo-3-(phenylcarbamoyl)butyl]-diethylazanium;hydrogen sulfate. Canonical SMILES: CC[NH+](CC)CCC(C(=O)NC1=CC=CC=C1)C(=O)NC2=CC=CC=C2.OS(=O)(=O)[O-]. Product ID: ACM52507558. Alfa Chemistry ISO 9001:2015 Certified.
Carbonylhydrido[6-(di-t-butylphosphinomethylene)-2-(N,N-diethylaminomethyl)-1,6-dihydropyridine]ruthenium(II), min. 98% Milstein Catalyst
Carbonylhydrido[6-(di-t-butylphosphinomethylene)-2-(N,N-diethylaminomethyl)-1,6-dihydropyridine]ruthenium(II), min. 98% Milstein Catalyst. Uses: Ruthenium catalyst for the direct synthesis of amides from alcohols and primary amines. ruthenium catalyst for the hydrogenation of esters in high yields under mild pressure and neutral conditions. ruthenium catalyst for the dehydrogenative coupling of alcohols to form esters in high yields under neutral conditions. ruthenium catalyst for the synthesis of amides from esters and amines with liberation of hydrogen gas. ruthenium catalyst for the hydrogenation of 3-methyl-2-oxalidinone. Additional or Alternative Names: 863971-63-5;Carbonylhydrido[6-(di-t-butylphosphinomethylene)-2-(N,N-diethylaminomethyl)-1,6-dihydropyridine]ruthenium(II);DTXSID40856225;Ruthenium(2+) hydride (2E)-2-[(di-tert-butylphosphanyl)methylidene]-6-[(diethylamino)methyl]-2H-pyridin-1-ide--carbon monooxide (1/1/1/1). Product Category: Ruthenium series catalysts. CAS No. 863971-63-5. Molecular formula: C20H35N2OPRu. Mole weight: 451.557g/mol. IUPACName: carbon monoxide;N-[[(6E)-6-(ditert-butylphosphanylmethylidene)pyridin-1-id-2-yl]methyl]-N-ethylethanamine;hydride;ruthenium(2+). Canonical SMILES: [H-].CCN(CC)CC1=CC=CC(=CP(C(C)(C)C)C(C)(C)C)[N-]1.[C-]#[O+].[Ru+2]. Product ID: ACM863971635. A
FIIN-1
FIIN-1 is a potent, irreversible and selective FGFR inhibitor with IC50s of 9.2, 6.2, 11.9 and 189 nM against FGFR1/2/3/4, respectively. FIIN-1 binds to FGFR1/2/3/4 and Flt1/4 with Kds of 2.8, 6.9, 5.4, 120 nM and 32, 120 nM, respectively. Synonyms: FGFR irreversible inhibitor-1; N-[3-[[3-(2,6-Dichloro-3,5-dimethoxyphenyl)-7-[[4-(diethylamino)butyl]amino]-3,4-dihydro-2-oxopyrimido[4,5-d]pyrimidin-1(2H)-yl]methyl]phenyl]-2-propenamide; Fibroblast Growth Factor Receptor Irreversible Inhibitor 1; N-[3-[[3-(2,6-Dichloro-3,5-dimethoxyphenyl)-7-[[4-(diethylamino)butyl]amino]-3,4-dihydro-2-oxopyrimido[4,5-d]pyrimidin-1(2H)-yl]methyl]phenyl]acrylamide. Grades: ≥95%. CAS No. 1256152-35-8. Molecular formula: C32H39Cl2N7O4. Mole weight: 656.60.
PD 161570
PD 161570. Group: Biochemicals. Alternative Names: N-[6- (2, 6-Dichlorophenyl) -2-[[4- (diethylamino) butyl]amino]pyrido[2, 3-d]pyrimidin-7-yl]-N'- (1, 1-dimethylethyl) urea; 1-tert-butyl-3-[6-(2,6-dichloro-phenyl)-2-(4-diethylamino-butylamino)pyrido[2,3-d]pyrimidin-7-yl]urea. Grades: Highly Purified. CAS No. 192705-80-9. Pack Sizes: 2mg, 5mg, 10mg, 25mg, 50mg. Molecular Formula: C26H35Cl2N7O. US Biological Life Sciences.
Worldwide
PD-161570
A novel FGF-1 receptor tyrosine kinase inhibitor which has been shown to effectively suppress constitutive phosphorylation of the FGF-1 receptor in human ovarian carcinoma cells. Group: Biochemicals. Alternative Names: N-[6- (2, 6-Dichlorophenyl) -2-[[4- (diethylamino) butyl]amino]pyrido[2, 3-d]pyrimidin-7-yl]-N'- (1, 1-dimethylethyl) urea; 1-Tert-butyl-3-[6-(2,6-dichloro-phenyl)-2-(4-diethylamino-butylamino)pyrido[2,3-d]pyrimidin-7-yl]urea. Grades: Highly Purified. CAS No. 192705-80-9. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
PD-161570
PD-161570 is a selective inhibitor of human FGF-1 receptor tyrosine kinase, with IC50 values to be 40, 262 and 3700 nM for FGFR1, PDGFR and EGFR tyrosine kinases, respectively. In addintion, PD-161570 inhibits FGFR receptor phosphorylation (IC50 = 622 nM) and growth of A121 cells in vitro. Synonyms: N-[6-(2,6-Dichlorophenyl)-2-[[4-(diethylamino)butyl]amino]pyrido[2,3-d]pyrimidin-7-yl]-N'-(1,1-dimethylethyl)urea; PD-161570; PD 161570; PD161570. CAS No. 192705-80-9. Molecular formula: C26H35Cl2N7O. Mole weight: 532.51.
PD-173074
PD 173074. Group: Biochemicals. Alternative Names: N-[2-[[4- (Diethylamino) butyl]amino]-6- (3, 5-dimethoxyphenyl) pyrido[2, 3-d]pyrimidin-7-yl]-N'- (1, 1-dimethylethyl) urea; PD 173074. Grades: Highly Purified. CAS No. 219580-11-7. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
PD-173074-d9
Labeled PD 173074. Group: Biochemicals. Alternative Names: N-[2-[[4- (Diethylamino) butyl]amino]-6- (3, 5-dimethoxyphenyl) pyrido[2, 3-d]pyrimidin-7-yl]-N'- (1, 1-dimethylethyl-d9) urea. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
A potent and selective FGFR1 tyrosine kinase inhibitor (IC50 = 21.5nM). Blocking of the FGFR signaling pathway by PD 173074 leads to self-renewal of stem cells via ERK1/2 activation. Treatment of FGF2-expressing human multipotent adipose-derived stem cells with PD173074 decreases dramatically their clonogenicity and differentiation potential. Group: Biochemicals. Alternative Names: PD173074, N-[2-[[4- (Diethylamino) butyl]amino]-6- (3, 5-dimethoxyphenyl) pyrido[2, 3-d]pyrimidin-7-yl]-N- (1, 1-dimethylethyl) urea. Grades: Highly Purified. CAS No. 219580-11-7. Pack Sizes: 2mg. US Biological Life Sciences.
Worldwide
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