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4-Phenylpiperidine-4-carboxylic acid hydrochloride98+%. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 250mg, 1g, 5g. US Biological Life Sciences.
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JDTic dihydrochloride
JDTic dihydrochloride is a highly selective antagonist for the κ-opioid receptor with IC50 value of 0.02nM without affecting the μ- or δ-opioid receptors. It is a 4-phenylpiperidine derivative and distantly structurally related to analgesic drugs such as meperidine and ketobemidone and more closely to the mu opioid antagonist alvimopan. It is structurally distinct from other kappa antagonists such as norbinaltorphimine. It is more selective and potent for KOR activity than other KOR antagonists. It is shown to block the antinociceptive response of nicotine in the tail-flick test with a dose-dependent manner. It can also block the nicotine withdrawal signs in mice vi... it can also block the nicotine withdrawal signs in mice via effecting the expression of a cpa associated with nicotine withdrawal. it is also reported to decrease the number of somatic withdrawal signs in morphine-dependent rats. it may produce antidepressant and anxiolytic effects and may be used in the treatment of addiction to cocaine and morphine. Synonyms: JDTic (2HCl);(3R)-1,2,3,4-Tetrahydro-7-hydroxy-N-[(1S)-1-[[(3R,4R)-4-(3-hydroxyphenyl)-3,4-dimethyl-1-piperidinyl]methyl]-2-methylpropyl]-3-isoquinolinecarboxamide hydrochloride;(R)-7-hydroxy-N-((S)-1-((3R,4R)-4-(3-hydroxyphenyl)-3,4- . Grades: 95%. CAS No. 785835-79-2. Molecular formula: C28H41Cl2N3O3. Mole weight: 538.55.
1-(4-Phenylpiperidin-4-yl)butan-1-one hydrochloride. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 1-(4-Phenylpiperidin-4-yl)butan-1-one hydrochloride, 15847-65-1, AC1MI0BY, SureCN1308247, NSC57801, EINECS 239-960-2, NSC-57801, 1-(4-Phenylpiperidin-4-yl)butan-1-one HCl. Product Category: Heterocyclic Organic Compound. CAS No. 15847-65-1. Molecular formula: C15H21NO.HCl. Mole weight: 267.794280 [g/mol]. Purity: 0.96. IUPACName: 1-(4-phenylpiperidin-4-yl)butan-1-one;hydrochloride. Canonical SMILES: CCCC(=O)C1(CCNCC1)C2=CC=CC=C2.Cl. Density: 1.008g/cm³. ECNumber: 239-960-2. Product ID: ACM15847651. Alfa Chemistry ISO 9001:2015 Certified.
(±)-Vesamicol hydrochloride
(±)-Vesamicol hydrochloride is an inhibitor of acetylcholine transport (Ki = 2 nM) that blocks the loading of acetylcholine into synaptic vesicles of cholinergic nerve terminals. The inhibition by Vesamicol attenuates acetylcholine neuronal signaling without direct effecys on signaling mechanisms. Synonyms: AH5183 hydrochloride; AH 5183 hydrochloride; (±)-trans-2-(4-Phenylpiperidinyl)cyclohexanol hydrochloride; 2-(4-Phenylpiperidino)cyclohexanol hydrochloride; Cyclohexanol, 2-(4-phenylpiperidino)-, hydrochloride. Grades: ≥99% by HPLC. CAS No. 120447-62-3. Molecular formula: C17H25NO.HCl. Mole weight: 295.85.
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