460738 38 9 Suppliers USA
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Product | Description | |
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Ecallantide Quick inquiry Where to buy Suppliers range | Ecallantide is a drug used for the treatment of hereditary angioedema and in the prevention of blood loss in cardiothoracic surgery. Synonyms: DX-88 cpd; EPI-KAL-2; Kalbitor. CAS No. 460738-38-9. Molecular formula: C305H442N88O91S8. Mole weight: 7053.83. | |
Ecallantide Quick inquiry Where to buy Suppliers range | HAE is caused by a mutation of the C1-inhibitor gene. Defective or missing C1-inhibitor permits activation of kallikrein, a protease that is responsible for liberating bradykinin from its precursor kininogen. An excess of bradykinin leads to fluid leakage from blood vessels, causing swelling of tissues typical of HAE.Ecallantide suppresses this pathogenetic mechanism by selectively and reversibly inhibiting the activity of plasma kallikrein. Uses: API. CAS No. 460738-38-9. Product ID: 10-101-160. |