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| Product | Description | |
|---|---|---|
| 5'-O-(4,4'-dimethoxytrityl)-2'-deoxyguanosine | 5'-O-(4,4'-dimethoxytrityl)-2'-deoxyguanosine. Group: Biochemicals. Alternative Names: 5'-DMT-2'-dG. Grades: Highly Purified. CAS No. 81144-43-6. Pack Sizes: 1g. US Biological Life Sciences. |  Worldwide |
| 5'-O-(4,4'-dimethoxytrityl)-2'-deoxyguanosine ≥98.5% (HPLC) | 5'-O-(4,4'-dimethoxytrityl)-2'-deoxyguanosine ≥98.5% (HPLC). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 250mg, 1g. US Biological Life Sciences. | Worldwide |
| 5'-O-(4,4'-Dimethoxytrityl)-N2-isobutyryl-2'-deoxyguanosine-3'-(methyl-N,N-diisopropyl)phosphoramidite | dG(ibu)-3'-Methoxy Phosphoramidite is a modified phosphoramidite designed for oligonucleotide synthesis. The guanine base is protected with an isobutyryl (ibu) group at the exocyclic amine to prevent undesired side reactions during the synthesis process. The 3'-hydroxyl group is replaced with a methoxy group, enhancing the stability and altering the structural properties of the resulting oligonucleotide. The phosphoramidite functionality ensures efficient coupling during automated oligonucleotide synthesis. This modification is particularly useful in creating oligonucleotides with increased chemical stability and resistance to enzymatic degradation, making it suitable for applications in therapeutic oligonucleotides, antisense RNA technologies, and advanced molecular biology research. Synonyms: dG(ibu)-3'-Methoxy Phosphoramidite; Guanosine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-N-(2-methyl-1-oxopropyl)-, 3'-[methyl N,N-bis(1-methylethyl)phosphoramidite]; Guanosine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-N-(2-methyl-1-oxopropyl)-, 3'-[methyl bis(1-methylethyl)phosphoramidite]; DNA G(iBu) OMe-amidite; 2'-Deoxyguanosine-(N-iBu)-3'-methyl-phosphoramidite. Grade: ≥98%. CAS No. 84416-84-2. Molecular formula: C42H53N6O8P. Mole weight: 800.88. |  |
| 5'-O-(4,4'-Dimethoxytrityl)-n2-isobutyryl-8-oxo-2'-deoxyguanosine,3'-[(2-cyanoethyl)-(N,N-diisopropyl)]phosphoramidite | 5'-O-(4,4'-Dimethoxytrityl)-n2-isobutyryl-8-oxo-2'-deoxyguanosine,3'-[(2-cyanoethyl)-(N,N-diisopropyl)]phosphoramidite. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 5'-O-(4,4'-DIMETHOXYTRITYL)-N2-ISOBUTYRYL-8-OXO-2'-DEOXYGUANOSINE, 3'-[(2-CYANOETHYL)-(N,N-DIISOPROPYL)]PHOSPHORAMIDITE;8-OXO-DG CEP. Product Category: Heterocyclic Organic Compound. CAS No. 143060-53-1. Molecular formula: C44H54N7O9P. Mole weight: 855.91. Product ID: ACM143060531. Alfa Chemistry ISO 9001:2015 Certified. |  |
| 2'-Deoxy-5'-O-DMT-guanosine | 2'-Deoxy-5'-O-DMT-guanosine is a remarkable biomedical compound, showcases immense potential in the realm of antiviral drug development. With its intricate chemical composition, this compound serves as a valuable precursor for synthesizing guanosine analogues which effectively impede viral replication. Synonyms: 5'-DMT-2'-dG; 5'-O-(4,4'-DIMETHOXYTRITYL)-2'-DEOXYGUANOSINE; 2-Amino-9-((2R,4S,5R)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-hydroxytetrahydrofuran-2-yl)-1H-purin-6(9H)-one. Grade: 98+%. CAS No. 81144-43-6. Molecular formula: C31H31N5O6. Mole weight: 569.61. | |
| 2'-Deoxy-5'-O-DMT-N2-isobutyrylguanosine | 2'-Deoxy-5'-O-DMT-N2-isobutyrylguanosine, an invaluable component employed in cutting-edge biomedical investigations, showcases promise in combatting diverse malignancies and viral afflictions. With its unparalleled configuration and attributes, it emerges as a potent instrument for scrutinizing mechanisms of DNA replication and mending. By harnessing this compound, one can delve into drug synthesis advancements and explore gene therapy, thereby illuminating potential remedies against prevalent conditions encompassing leukemia, lung cancer, and HIV. Synonyms: N2-iso-Butyroyl-2'-deoxy-5'-O-(4,4'-dimethoxytrityl)-guanosine; N2-Isobutyryl-2'-deoxy-5'-O-DMT-D-guanosine; 2'-Deoxy-5'-O-DMT-N2-isobutyryl-D-guanosine; 5'-O-DMT-N2-isobutyryl-2'-deoxyguanosine; N2-Isobutyryl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxyguanosine; iBu-DMT-dG; DMT-N-IB-DG; 5'-O-(Bis(4-methoxyphenyl)benzyl)-2'-deoxy-N-(2-methyl-1-oxopropyl)guanosine. Grade: ≥98% by HPLC. CAS No. 68892-41-1. Molecular formula: C35H37N5O7. Mole weight: 639.70. | |
| 2'-Deoxy-N2-DMF-5'-O-DMT-guanosine | 2'-Deoxy-N2-DMF-5'-O-DMT-guanosine is a crucial compound extensively used in the biomedical industry. This product plays a significant role in the synthesis of nucleoside analogs and anti-viral drugs targeting diseases such as HIV and hepatitis C. Its unique chemical structure allows for further modification, making it a versatile tool in drug development and pharmaceutical research. Synonyms: 5'-DMT-DMF-dG; 2'-Deoxy-5'-O-DMT-N2-(dimethylamino)methylidene-D-guanosine; Guanosine, 5'-O-[bis(4-methoxyphenyl)?phenylmethyl]?-2'-deoxy-N-[(dimethylamino)?methylene]?-; 2'-Deoxy-N2-DMF-5'-O-DMT-D-guanosine; N2-DMF-5'-O-DMT-2'-deoxy-D-guanosine; 5'-O-DMT-N2-(dimethylamino)methylidene-2'-Deoxyguanosine; 5'-O-(4,4'-Dimethoxytrityl)-N2-dimethylformamidine-2'-deoxyguanosine; N2-Dimethylformamidine-5'-O-(4,4'-dimethoxytrityl)-2'-deoxyguanosine; 9-{5-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-2-deoxy-β-D-threo-pentofuranosyl}-2-{(E)-[(dimethylamino)methylene]amino}-1,9-dihydro-6H-purin-6-one. Grade: ≥98% by HPLC. CAS No. 40094-22-2. Molecular formula: C34H36N6O6. Mole weight: 624.70. | |
| 3'-dG(N-Ac) CE Phosphoramidite | 3'-dG(N-Ac) CE Phosphoramidite is a modified phosphoramidite reagent designed for solid-phase oligonucleotide synthesis, enabling site-specific incorporation of N-acetyl-protected deoxyguanosine (dG) at the 3'-end of DNA strands. Synonyms: 3'-dG(N-Ac) Phosphoramidite; 3'-dG(Ac) 2'-phosphoramidite; 3'-dG(Ac) 2'-amidite; N4-Acetyl-5'-O-(4,4'-dimethoxytrityl)-3'-deoxyguanosine-2'-cyanoethyl phosphoramidite; 3'-dG(Ac) Phosphoramidite. Grade: ≥97%. Molecular formula: C42H50N7O8P. Mole weight: 811.88. | |
| 5'-O-(Dimethoxytrityl)-N2-Benzyl-2'-deoxyguanosine | 5'-O-(Dimethoxytrityl)-N2-Benzyl-2'-deoxyguanosine is a pivotal compound employed in the biomedical industry, finding its use in synthesizing nucleoside analogues and diverse pharmaceuticals. In the realm of medicine, it assumes the role of an intermediary component facilitating the research and development of therapeutic drugs aimed at research of viral infections and oncological afflictions. Synonyms: Guanosine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-N-(phenylmethyl)-; N-Benzyl-5'-O-[bis(4-methoxyphenyl)(phenyl)methyl]-2'-deoxyguanosine; 2-(Benzylamino)-9-((2R,4S,5R)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-hydroxytetrahydrofuran-2-yl)-1H-purin-6(9H)-one; 5'-O-(4,4'-Dimethoxytrityl)-N2-Benzyl-2'-deoxyguanosine. Grade: 95%. CAS No. 209785-64-8. Molecular formula: C38H37N5O6. Mole weight: 659.73. | |
| 5'-O-(Dimethoxytrityl)-N2-ethyl-2'-deoxyguanosine | 5'-O-(Dimethoxytrityl)-N2-ethyl-2'-deoxyguanosine is a paramount constituent employed in the biomedical domain for oligonucleotide research and development, specifically used for the research of targeting diverse viral afflictions and malignancies. Synonyms: Guanosine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-N-ethyl-; 5'-O-(4,4'-Dimethoxytrityl)-N2-ethyl-2'-deoxyguanosine; 2'-Deoxy-5'-O-[(2,3-dimethoxyphenyl)(diphenyl)methyl]-N-ethylguanosine; 5'-O-[Bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-N-ethyl-guanosine; 9-((2R,4S,5R)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-hydroxytetrahydrofuran-2-yl)-2-(ethylamino)-1,9-dihydro-6H-purin-6-one. Grade: ≥95%. CAS No. 337380-92-4. Molecular formula: C33H35N5O6. Mole weight: 597.67. | |
| 5'-O-DMT-2'-fluoro-N2-isobutyryl-2'-Deoxy-guanosine 3'-CE phosphoramidite | 5'-O-DMT-2'-Fluoro-N2-isobutyryl-2'-Deoxy-guanosine 3'-CE phosphoramidite is a modified phosphoramidite used in oligonucleotide synthesis. It features a 5'-dimethoxytrityl (DMT) protecting group at the 5'-hydroxyl position, a 2'-fluoro modification to enhance stability and binding affinity, an N2-isobutyryl group protecting the exocyclic amine of the guanine base, and a cyanoethyl (CE) group on the 3'-phosphoramidite. These modifications make it suitable for synthesizing oligonucleotides with improved resistance to enzymatic degradation and enhanced hybridization properties, which are crucial for applications in research, diagnostics, and therapeutics. Synonyms: 2'-Deoxy-5'-O-DMT-2'-fluoro-N2-isobutyrylguanosine 3'-CE phosphoramidite; 2'-F-iBu-G-CEP; 5'-O-[bis(4-methoxyphenyl)?phenylmethyl]?-2'-deoxy-2'-fluoro-N-(2-methyl-1-oxopropyl)?-Guanosine 3'-[2-cyanoethyl N,?N-bis(1-methylethyl)?phosphoramidite]; DMT-2'Fluoro-dG(iBu) Phosphoramidite; 2'-F-dG(iBu) 3'-CE phosphoramidite; DMT-2'-F-dG(iBu)-CE Phosphoramidite; 2'-F-dG(iBu)-CE Phosphoramidite; 2'-Fluoro-N2-isobutyryl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxyguanosine-3'-CE-Phosphoramidite. Grade: ≥95%. CAS No. 144089-97-4. Molecular formula: C44H53FN7O8P. Mole weight: 857.91. | |
| 5'-O-DMT-N2-DMF-2'-deoxyguanosine 3'-CE phosphoramidite | 5'-O-DMT-N2-DMF-2'-deoxyguanosine 3'-CE phosphoramidite, an indispensable constituent in the biomedical sector, finds extensive application in the synthesis of oligonucleotides for diagnostics and research studies. Its pivotal role encompasses the progress of nucleic acid-centered therapies and drug exploration, with a primary focus on combatting a wide range of diseases, encompassing cancer, genetic disorders, and viral infections. Synonyms: 5'-O-DMT-N2-(dimethylamino)-2'-Deoxy Guanosine Phosphoramidite; DMF-dG CEP; 5'-Dimethoxytrityl-N-dimethylformamidine-2'-deoxyGuanosine, 3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; Dmf-dG-CE Phosphoramidite; 2'-Deoxy-N2-DMF-5'-O-DMT-guanosine 3'-CE phosphoramidite; 5'-O-[bis(4-methoxyphenyl)?phenylmethyl]?-2'-deoxy-N-[(dimethylamino)?methylene]?-Guanosine 3'-[2-cyanoethyl N,?N-bis(1-methylethyl)?phosphoramidite]. Grade: ≥98% by HPLC. CAS No. 330628-04-1. Molecular formula: C43H53N8O7P. Mole weight: 824.93. | |
| 8-oxo-dG-CE Phosphoramidite | 8-oxo-dG-CE Phosphoramidite is an indispensable compound assuming a pivotal role in oligonucleotide research and development. Its contributes to the exploration of therapeutic drugs aimed at DNA repair and ailments associated with oxidative stress. Synonyms: 5'-Dimethoxytrityl-N2-isobutyryl-8-oxo-deoxyguanosine-3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; 8-OXO-dG(ibu) Phosphoramidite; 5'-O-(4,4'-Dimethoxytrityl)-N2-isobutyryl-8-oxo-2'-deoxyguanosine, 3'-[(2-cyanoethyl)-(N,N-diisopropyl)]phosphoramidite; (2R,3S,5R)-2-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(2-isobutyramido-6,8-dioxo-1,6,7,8-tetrahydro-9H-purin-9-yl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite; DNA 8-oxo-G(iBu) amidite. Grade: 95%. CAS No. 143060-53-1. Molecular formula: C44H54N7O9P. Mole weight: 855.93. | |
| 8-OXO-dG(dmf) Phosphoramidite | 8-OXO-dG(dmf) Phosphoramidite is a modified phosphoramidite in which the guanine base is oxidized at the 8-position to form 8-oxo-guanine, with the exocyclic amine at the 2-position protected by a dimethylformamidine (dmf) group. The sugar moiety is functionalized with a 3'-cyanoethyl (CE) phosphoramidite group for incorporation into oligonucleotides via automated DNA synthesis. This modification mimics oxidative DNA damage, making it a valuable tool for studying the biological effects of oxidative stress, DNA repair mechanisms, and mutagenesis. It is widely used in molecular biology and biochemistry research to investigate the role of 8-oxo-guanine in genomic stability and disease processes. Synonyms: OXO-dG(N-dmf) Phosphoramidite; OXO-dG(N-dmf) CE Phosphoramidite; 5'-Dimethoxytrityl-N2-dimethylformamidine-8-oxo-deoxyguanosine-3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; 8-OXO-2'-deoxy-G(DMF) Phosphoramidite; 5'-O-(4,4'-Dimethoxytrityl)-N2-dimethylformamidine-8-oxo-2'-deoxyguanosine, 3'-[(2-cyanoethyl)-(N,N-diisopropyl)]phosphoramidite; 8-OXO-dG(dmf) CE Phosphoramidite; 8-OXO-dG(dmf) 3'-CE Phosphoramidite. Grade: ≥98%. CAS No. 1850359-96-4. Molecular formula: C43H53N8O8P. Mole weight: 840.92. | |
| 9-(2'-Deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)-N2-isobutyrylguanine 3'-CE phosphoramidite | The 9-(2'-Deoxy-5'-O-DMT-2'-fluoro-beta-D-arabinofuranosyl)-N2-isobutyrylguanine 3'-CE phosphoramidite has been proven effective against cancer. Synonyms: 5'-O-DMT-2'-fluoro-N2-isobutyryl-2'-arabinofuranosyl-deoxyguanosine 3'-CE phosphoramidite; 2'-F-2'-ara-N2-ibu-dG phosphoramidite; Propanamide, N-[9-[5-O-[bis(4-methoxyphenyl)phenylmethyl]-3-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-2-deoxy-2-fluoro-β-D-arabinofuranosyl]-6,9-dihydro-6-oxo-1H-purin-2-yl]-2-methyl-; N2-iso-Butyroyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxy-fluoro-2'-arabinoguanosine-3'-CED-phosphoramidite; 9-{5-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-3-O-[(2-cyanoethoxy)(diisopropylamino)phosphino]-2-deoxy-2-fluoro-β-D-arabinofuranosyl}-2-(isobutyrylamino)-1,9-dihydro-6H-purin-6-one. Grade: ≥97% by HPLC. CAS No. 1404463-20-2. Molecular formula: C44H53FN7O8P. Mole weight: 857.93. | |
| dG(iBu)-PACE Phosphoramidite | dG-PACE Phosphoramidite is a key reagent in the biomedical industry used for the synthesis of oligonucleotides. It contains a modified nucleotide base that facilitates the detection of SNP mutations associated with diseases such as cancer and cystic fibrosis. Its use in site-specific labeling of DNA strands has also been found useful in gene expression studies. Synonyms: DNA G(iBu) PACE amidite; dG-PACE Phosphoramidite; Guanosine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-N-(2-methyl-1-oxopropyl)-, 3'-[P-[2-(2-cyano-1,1-dimethylethoxy)-2-oxoethyl]-N,N-bis(1-methylethyl)phosphonamidite]; 5'-Dimethoxytrityl-N-isobutyryl-2'-deoxyguanosine, 3'-O-(N,N-diisopropylamino)-phosphinyl-1,1-dimethyl-2-cyanoethyl acetate. Grade: ≥95%. CAS No. 411234-26-9. Molecular formula: C48H60N7O9P. Mole weight: 910.01. | |
| dG(N-Pac) CE Phosphoramidite | dG(N-Pac) CE Phosphoramidite is a modified phosphoramidite reagent designed for solid-phase oligonucleotide synthesis, enabling site-specific incorporation of deoxyguanosine (dG) with an N-phenoxyacetyl (N-Pac) protecting group. This protecting group is part of the UltraMILD chemistry, which allows for the deprotection of oligonucleotides under milder conditions compared to standard protocols. Synonyms: dG(N-Pac) Phosphoramidite; dG(Pac) CE Phosphoramidite; 5'-O-DMT-N2-phenoxyacetyl-2'-Deoxy-guanosine 3'-CE phosphoramidite; 2'-Deoxy-5'-O-DMT-N2-phenoxyacetylguanosine 3'-CE phosphoramidite; Pac-dG-CEP; DMT-dG(Pac) Phosphoramidite; dG(Pac) 3'-CE phosphoramidite; DMT-dG(Pac)-CE Phosphoramidite; N2-phenoxyacetyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxyguanosine-3'-CE-Phosphoramidite; Guanosine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-N-(phenoxyacetyl)-, 3'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite]. Grade: ≥97%. CAS No. 110522-83-3. Molecular formula: C48H54N7O9P. Mole weight: 903.97. | |
| DMT-dG(Ac)-5'-CE Reverse Phosphoramidite | DMT-dG(Ac)-5'-CE Reverse Phosphoramidite is a modified phosphoramidite reagent designed for solid-phase oligonucleotide synthesis, enabling site-specific incorporation of deoxyguanosine (dG) with an N-acetyl protecting group at the 5'-end of DNA strands. This reagent features a reverse configuration where the DMT group is attached to the 3'-OH and the phosphoramidite to the 5'-OH, allowing synthesis in the 5' to 3' direction. It is particularly useful for synthesizing oligonucleotides with hairpin loops containing parallel strands or nuclease-resistant linkages. Synonyms: idG(N-Ac) Phosphoramidite; idG(N-Ac) CE Phosphoramidite; 3'-DMTr-dG(Ac)-CE Reverse; N2-Acetyl-3'-O-(4,4'-dimethoxytrityl)-2'-deoxyguanosine-5'-cyanoethyl phosphoramidite; DMT-dG(Ac)-CE Inverted Phosphoramidite; N2-Ac-3'-O-DMTr-2'-deoxyguanosine 5'-O-CE-phosphoramidite; 3'-O-DMTr-dG(Ac)-5'-CE-Phosphoramidite; Rev dG(Ac). Grade: ≥97%. Molecular formula: C42H50N7O8P. Mole weight: 811.88. | |
| DMT-dG(DMF)-5'-CE Reverse Phosphoramidite | DMT-dG(DMF)-5'-CE Reverse Phosphoramidite is a modified phosphoramidite reagent designed for solid-phase oligonucleotide synthesis, enabling site-specific incorporation of deoxyguanosine (dG) with an N-dimethylformamidine (DMF) protecting group at the 5'-end of DNA strands. This reagent features a reverse configuration where the DMT group is attached to the 3'-OH and the phosphoramidite to the 5'-OH, allowing synthesis in the 5' to 3' direction. It is particularly useful for synthesizing oligonucleotides with hairpin loops containing parallel strands or nuclease-resistant linkages. Synonyms: idG(N-dmf) Phosphoramidite; idG(N-dmf) CE Phosphoramidite; 3'-DMTr-dG(DMF)-CE Reverse; N2-Dimethylformamidine-3'-O-(4,4'-dimethoxytrityl)-2'-deoxyguanosine-5'-cyanoethyl phosphoramidite; DMT-dG(DMF)-CE Inverted Phosphoramidite; N2-DMF-3'-O-DMTr-2'-deoxyguanosine 5'-O-CE-phosphoramidite; 3'-O-DMTr-dG(DMF)-5'-CE-Phosphoramidite; Rev dG(DMF); Guanosine, 3'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-N-[(dimethylamino)methylene]-, 5'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite]. Grade: ≥97%. CAS No. 261728-23-8. Molecular formula: C43H53N8O7P. Mole weight: 824.91. | |
| DMT-dG(iBu)-5'-CE Reverse Phosphoramidite | DMT-dG(iBu)-5'-CE Reverse Phosphoramidite is a compound used in the synthesis of oligonucleotides, specifically designed for automated DNA synthesis systems. It is essential for the efficient and precise assembly of custom DNA sequences in laboratory settings, ensuring that each nucleotide is added correctly and in the desired sequence during automated oligonucleotide synthesis processes. Synonyms: 3'-DMTr-dG(iBu)-CE Reverse; N2-Isobutyryl-3'-O-(4,4'-dimethoxytrityl)-2'-deoxyguanosine-5'-cyanoethyl phosphoramidite; DMT-dG(iBu)-CE Inverted Phosphoramidite; Guanosine, 3'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-N-(2-methyl-1-oxopropyl)-, 5-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]; N2-iBu-3'-O-DMTr-2'-deoxyguanosine 5'-O-CE-phosphoramidite; 3'-O-DMTr-dG(iBu)-5'-CE-Phosphoramidite; Rev dG(iBu). Grade: ≥95%. CAS No. 140839-24-3. Molecular formula: C44H54N7O8P. Mole weight: 839.92. | |
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