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Methanone, (3,5-dimethyl-4-isoxazolyl)[4-(4-fluorophenyl)-1-piperazinyl]-. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Methanone, (3,5-dimethyl-4-isoxazolyl)[4-(4-fluorophenyl)-1-piperazinyl]-. Product Category: Heterocyclic Organic Compound. CAS No. 945201-72-9. Product ID: ACM945201729. Alfa Chemistry ISO 9001:2015 Certified.
PF 5006739
PF 5006739 is a potent inhibitor of casein kinases 1 delta (CK1δ) and 1 epsilon (CK1ε) (IC50 values are 3.9 and 17 nM, respectively). It mediates circadian rhythm phase-delaying effects in vivo. Synonyms: PF 5006739; PF5006739; PF-5006739; 4-[4-(4-Fluorophenyl)-1-[1-(3-isoxazolylmethyl)-4-piperidinyl]-1H-imidazol-5-yl]-2-Pyrimidinamine; 4-{4-(4-Fluorophenyl)-1-[1-(1,2-oxazol-3-ylmethyl)piperidin-4-yl]-1H-imidazol-5-yl}pyrimidin-2-amine. Grades: ≥98% by HPLC. CAS No. 1293395-67-1. Molecular formula: C22H22FN7O. Mole weight: 419.46.
Rupintrivir
Rupintrivir is a potent and selective irreversible human rhinovirus (HRV) 3C protease inhibitor (EC50 = 5 nM). It has been demonstrated to have in vitro activity against all HRVs tested, consistent with its interaction with a strictly conserved subset of amino acids in the 3C protease. It blocks processing of viral proteins, thus blocking viral replication. Uses: Antiviral agents. Synonyms: Ethyl (2E,4S)-4-[[(2R,5S)-2-[(4-fluorophenyl)methyl]-6-methyl-5-[[(5-methyl-3-isoxazolyl)carbonyl]amino]-1,4-dioxoheptyl]amino]-5-[(3S)-2-oxo-3-pyrrolidinyl]-2-pentenoate; AG-7088; AG7088; AG 7088. Grades: ≥98%. CAS No. 223537-30-2. Molecular formula: C31H39FN4O7. Mole weight: 598.66.
Rupintrivir-d4
Labeled Rupintrivir. Rupintrivir (formerly AG7088) is an irreversible inhibitor of the human rhinovirus (HRV) 3C protease that has been demonstrated to have in vitro activity against all HRVs tested, consistent with its interaction with a strictly conserved subset of amino acids in the 3C protease. Group: Biochemicals. Alternative Names: 2E,4S)-4-[[(2R,5S)-2-[(4-Fluorophenyl)methyl]-6-methyl-5-[[(5-methyl-3-isoxazolyl-d4)carbonyl]amino]-1,4-dioxoheptyl]amino]-5-[(3S)-2-oxo-3-pyrrolidinyl]-2-pentenoic Acid; AG 7088-d4. Grades: Highly Purified. Pack Sizes: 250ug. US Biological Life Sciences.
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