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5-Aza-2'-deoxycytidine. Group: Biochemicals. Alternative Names: Decitabine; 4-Amino-1-(2-deoxy-b-D-ribofuranosyl)-1,3,5-triazin-2(1H)-one. Grades: Highly Purified. CAS No. 2353-33-5. Pack Sizes: 100mg, 250mg, 500mg, 1g, 2g. Molecular Formula: C8H12N4O4. US Biological Life Sciences.
Worldwide
5-aza-2'-deoxycytidine triphosphate
5-Aza-dCTP is a inhibitor of DNA methylation and an antileukemic agent. It has been used to reactivate silent tumor suppressor genes. Synonyms: 5-Aza-2'-deoxycytidine-5'-triphosphate. CAS No. 72052-96-1. Product ID: PAP-099. Molecular formula: C8H15N4O13P3. Mole weight: 468.15. Product Keywords: Anti-tumor Series; PAP-099; 5-aza-2'-deoxycytidine triphosphate; 72052-96-1; 5-Aza-2'-deoxycytidine-5'-triphosphate. Chemical Name: 5-Aza-2'-deoxycytidine-5'-triphosphate. Grade: Pharmaceutical grade. Applications: It has been used to reactivate silent tumor suppressor genes.
5-Aza-2-deoxycytidine. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 25mg. US Biological Life Sciences.
Worldwide
Decitabine, DNA Methyltransferase Inhibitor. (5-Aza-2-deoxycytidine; NSC-127716, 2'-Deoxy-5-azacytidine; 4-Amino-1-(2-deoxy-B-D-erythropentofuranosyl)-1,3,5-triazin-2(1H)-one)
Inhibits DNA methyltransferase. Induces demethylation and reactivation of silenced genes. Group: Biochemicals. Alternative Names: 5-Aza-2-deoxycytidine; NSC-127716, 2'-Deoxy-5-azacytidine; 4-Amino-1-(2-deoxy-B-D-erythropentofuranosyl)-1,3,5-triazin-2(1H)-on. Grades: Highly Purified. CAS No. 2353-33-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
5-Aza-2'-deoxyuridine (α/β mixture)
5-Aza-2'-deoxyuridine is a metabolite of 5-aza-2'-deoxycytidine, a cancer treatment, in particular to inhibit the growth of pancreatic endocrine tumor cell lines. Synonyms: 1-(2-Deoxy-D-erythro-pentofuranosyl)-1,3,5-triazine-2,4(1H,3H)-dione; 1-(2-Deoxy-D-erythro-pentofuranosyl)-s-triazine-2,4(1H,3H)-dione. Grade: 96%. Molecular formula: C8H11N3O5. Mole weight: 229.19.
5-Aza-2'-deoxyuridine (β Isomer)
5-Aza-2'-deoxyuridine is a metabolite of 5-aza-2'-deoxycytidine, a cancer treatment, in particular to inhibit the growth of pancreatic endocrine tumor cell lines. Synonyms: 1-(2-Deoxy-β-D-erythro-pentofuranosyl)-1,3,5-triazine-2,4(1H,3H)-dione; 5-Aza-2'-deoxy-β-uridine. Grade: 96%. CAS No. 25501-08-0. Molecular formula: C8H11N3O5. Mole weight: 229.19.
5-Aza-dCTP
5-Aza-dCTP, a well-known nucleoside analogue is extensively employed in epigenetic and oncological surveys. Its mechanism of action encompasses subduing DNA methylation and augmenting DNA demethylation that instigates the revival of detained genes. Additionally, 5-Aza-dCTP is frequently administered in accompaniment with other therapeutic agents to tackle diverse malignancies such as leukemia and lung cancer. Synonyms: (Decitabine triphosphate); 5-Aza-2'-deoxycytidine-5'-triphosphate, Sodium salt. Grade: ≥ 95% by HPLC at 267 nm. CAS No. 72052-96-1. Molecular formula: C8H15N4O13P3 (free acid). Mole weight: 468.14 (free acid).
5-Aza-N6-benzoyl-5'-O-DMT-2'-deoxycytidine 3'-CE phosphoramidite, a bio-molecular tool, facilitates the integration of 5-aza-2'-deoxycytidine into oligonucleotides. This inhibits DNA methyltransferase and affords therapeutic benefits such as anti-cancer activity. The phosphoramidite reagent is a research asset that enables differential and accurate DNA sequence modification for targeted epigenetic investigation. It thus contributes to newer approaches in therapeutic interventions. Synonyms: (2R,3S,5R)-2-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(2-oxo-4-(2-phenoxyacetamido)-1,3,5-triazin-1(2H)-yl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite; 929904-98-3. CAS No. 929904-98-3. Molecular formula: C46H53N6O9P. Mole weight: 864.92.
Decitabine
Decitabine is a potent inhibitor of DNA methylation, used to treat myelodysplastic syndrome (MDS). Synonyms: 5-Aza-2'-deoxycytidine; 5-Azadeoxycytidine; Dacogen; Deoxycytidine, 5-aza-2'-deoxycytidine. Grade: ≥ 98% by HPLC. CAS No. 2353-33-5. Molecular formula: C8H12N4O4. Mole weight: 228.21.
Decitabine
Decitabine (NSC 127716) is an orally active deoxycytidine analogue antimetabolite and a DNA methyltransferase inhibitor. Decitabine incorporates into DNA in place of cytosine can covalently trap DNA methyltransferase to DNA causing irreversible inhibition of the enzyme. Decitabine induces cell G2/M arrest and cell apoptosis. Decitabine has potent anticancer activity [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 5-Aza-2'-deoxycytidine; 5-AZA-CdR; NSC 127716. CAS No. 2353-33-5. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg; 1 g; 2 g. Product ID: HY-A0004.
Decitabine-15N4
Decitabine-15N4 is used as an internal standard for the quantification of decitabine. Decitabine induces dose-dependent inhibition of DNA methyltransferases and hypomethylation of DNA. Synonyms: 5-aza-2'-Deoxycytidine-15N4; DAC-15N4; UNII-LXU5241LCL; LXU5241LCL; (S)-(+)-Decursinol angelate. Grade: ≥95%. Molecular formula: C8H12N4O4. Mole weight: 232.2.
Decitabine (Standard)
Decitabine (Standard) is the analytical standard of Decitabine. This product is intended for research and analytical applications. Decitabine (NSC 127716) is an orally active deoxycytidine analogue antimetabolite and a DNA methyltransferase inhibitor. Decitabine incorporates into DNA in place of cytosine can covalently trap DNA methyltransferase to DNA causing irreversible inhibition of the enzyme. Decitabine induces cell G2/M arrest and cell apoptosis. Decitabine has potent anticancer activity [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 5-Aza-2'-deoxycytidine (Standard); 5-AZA-CdR (Standard); NSC 127716 (Standard). CAS No. 2353-33-5. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-A0004R.
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