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| Product | Description | |
|---|---|---|
| 5-azacytidine | 5-azacytidine is a pyrimidine nucleoside analog that specifically inhibits DNA methylation by trapping DNA methyltransferases. Synonyms: Azacitidine; Azacytidine; Ladakamycin. CAS No. 320-67-2. Molecular formula: C8H12N4O5. Mole weight: 244.20. |  |
| 5-Azacytidine | 5-Azacytidine (Azacitidine; 5-AzaC; Ladakamycin) is a nucleoside analogue of cytidine that specifically inhibits DNA methylation. 5-Azacytidine is incorporated into DNA to covalently trap DNA methyltransferases and contributes to reverse epigenetic changes [1] [2]. 5-Azacytidine induces cell autophagy [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Azacitidine; 5-AzaC; Ladakamycin. CAS No. 320-67-2. Pack Sizes: 10 mM * 1 mL; 100 mg; 200 mg; 500 mg. Product ID: HY-10586. |  |
| 5-Azacytidine | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. |  |
| 5-Azacytidine | A potent growth inhibitor and cytotoxic agent. It acts as a demethylating agent by inhibiting DNA methyltransferase. Group: Biochemicals. Alternative Names: Azacitidine; 4-Amino-1- β-D-ribofuranosyl-1,3,5-triazin-2(1H)-one; 5-AC; 5-AZC; 5-AZCR; 5-AzaC; Antibiotic U 18496; Azacytidine; Ladakamycin; Ledakamycin; Mylosar; NSC 102816; NSC 103-627; U 18496; Vidaza; WR 183027. Grades: Highly Purified. CAS No. 320-67-2. Pack Sizes: 1g, 5g, 10g. Molecular Formula: C8H12N4O5, Molecular Weight: 244.2. US Biological Life Sciences. |  Worldwide |
| 5-Azacytidine-13C4 | Labelled Azacytidine, a potent growth inhibitor and cytotoxic agent. It acts as a demethylating agent by inhibiting DNA methyltransferase. Synonyms: Azacitidine-13C4; 4-Amino-1-β-D-ribofuranosyl-1,3,5-triazin-2(1H)-one-13C4; 5-AC-13C4; 5-AZC-13C4; 5-AZCR-13C4; 5-AzaC-13C4; Antibiotic U 18496-13C4; Azacytidine-13C4; Ladakamycin-13C4; Ledakamycin-13C4; Mylosar-13C4; NSC 102816-13C4; NSC 103-627-13C4; U 18496-13C4; Vidaza-13C4; WR 183027-13C4. Molecular formula: C4[13C]4H12N4O5. Mole weight: 248.18. | |
| 5-Azacytidine-15N4 | Labeled Azacytidine, a potent growth inhibitor and cytotoxic agent. It acts as a demethylating agent by inhibiting DNA methyltransferase. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| 5-Azacytidine-[15N4] | Labelled Azacytidine, a potent growth inhibitor and cytotoxic agent. It acts as a demethylating agent by inhibiting DNA methyltransferase. Synonyms: Azacitidine-15N4; 5-Azacytidine-15N4; [15N4]-Azacytidine; 4-Amino-1-β-D-ribofuranosyl-1,3,5-triazin-2(1H)-one-15N4; 5-AC-15N4; 5-AZC-15N4; 5-AZCR-15N4; 5-AzaC-15N4; Antibiotic U 18496-15N4; Azacytidine-15N4; Ladakamycin-15N4; Ledakamycin-15N4; Mylosar-15N4; NSC 102816-15N4; NSC 103-627-15N4; Vidaza-15N4. Grade: 98%; 99% atom 15N. Molecular formula: C8H12[15N]4O5. Mole weight: 248.18. | |
| 5-Azacytidine-15N4 5'-Monophosphate | A labelled metabolite of 5-Azacytidine. Synonyms: 4-Amino-1-(5-O-phosphono-β-D-ribofuranosyl)-1,3,5-triazin-2(1H)-one-15N4; 4-Amino-1-β-D-ribofuranosyl-s-triazin-2(1H)-one 5'-Phosphate-15N4. Molecular formula: C8H13[15N]4O8P. Mole weight: 328.16. | |
| 5-Azacytidine 5'-Diphosphate | 5-Azacytidine 5'-Diphosphate is a phosphorylated metabolite of 5-Azacytidine. Group: Biochemicals. Alternative Names: 4-Amino-1-[5-O-[hydroxy (phosphonooxy) phosphinyl]- β-D-ribofuranosyl]-1,3,5-triazin-2(1H)-one; 4-Amino-1- β-D-ribofuranosyl-s-triazin-2(1H)-one 5'-Pyrophosphate; 5-Azacitidine 5'-Diphosphate. Grades: Highly Purified. CAS No. 2226-73-5. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| 5-Azacytidine 5'-Diphosphate | 5-Azacytidine 5'-Diphosphate is a phosphorylated metabolite of 5-Azacytidine. Synonyms: 4-Amino-1-[5-O-[hydroxy(phosphonooxy)phosphinyl]-β-D-ribofuranosyl]-1,3,5-triazin-2(1H)-one; 4-Amino-1-β-D-ribofuranosyl-s-triazin-2(1H)-one 5'-Pyrophosphate; 5-Azacitidine 5'-Diphosphate. CAS No. 2226-73-5. Molecular formula: C8H14N4O11P2. Mole weight: 404.16. | |
| 5-Azacytidine 5'-monophosphate | 5-Azacytidine 5'-monophosphate. Group: Biochemicals. Grades: Highly Purified. CAS No. 2226-72-4. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. Molecular Formula: C8H13N4O8P. US Biological Life Sciences. | Worldwide |
| 5-Azacytidine 5'-Monophosphate | A metabolite of 5-Azacytidine. This compound contains sodium chloride and water. Uses: A metabolite of 5-azacytidine. this compound contains sodium chloride and water. Synonyms: 4-Amino-1-(5-O-phosphono-β-D-ribofuranosyl)-1,3,5-triazin-2(1H)-one; 4-Amino-1-β-D-ribofuranosyl-s-triazin-2(1H)-one 5'-Phosphate. Grade: 60%. CAS No. 2226-72-4. Molecular formula: C8H13N4O8P. Mole weight: 324.18. | |
| 5-Azacytidine 5'-Triphosphate | 5-Azacytidine 5'-Triphosphate is a modified nucleotide analog derived from cytidine. It contains azacytidine, a cytidine analog where the carbon at position 5 is replaced by a nitrogen atom, and it is phosphorylated at the 5' position with a triphosphate group. This modification makes it useful for various applications in molecular biology and biochemistry, particularly in RNA and DNA research. It can be incorporated into RNA or DNA during synthesis, enabling studies related to epigenetics, gene regulation, and RNA metabolism. Uses: A metabolite of 5-azacytidine. Synonyms: 5-Aza CTP; 4-Amino-1-[5-O-[hydroxy[[hydroxy(phosphonooxy)phosphinyl]oxy]phosphinyl]-β-D-ribofuranosyl]-1,3,5-triazin-2(1H)-one; 4-Amino-1-β-D-ribofuranosyl-s-triazin-2(1H)-one 5'-Triphosphate; 5-Azacytidine Triphosphate; s-Triazin-2(1H)-one, 4-amino-1-β-D-ribofuranosyl-, 5'-(tetrahydrogen triphosphate); s-Triazin-2(1H)-one, 4-amino-1-β-D-ribofuranosyl-, 5'-triphosphate. Grade: ≥97%. CAS No. 2226-74-6. Molecular formula: C8H15N4O14P3. Mole weight: 484.14. | |
| 5-Azacytidine 5'-triphosphatediscontinued | 5-Azacytidine 5'-triphosphatediscontinued. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 4-Amino-1-[5-O-[hydroxy[[hydroxy(phosphonooxy)phosphinyl]oxy]phosphinyl]-β-D-ribofuranosyl]-1,3,5-triazin-2(1H)-one; 4-Amino-1-β-D-ribofuranosyl-s-triazin-2(1H)-one 5'-Triphosphate; 5-Azacytidine Triphosphate. Product Category: Heterocyclic Organic Compound. CAS No. 2226-74-6. Molecular formula: C8H15N4O14P3. Mole weight: 484.14. Purity: 0.96. IUPACName: [[(2S,3S,4R,5R)-5-(4-amino-2-oxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]amino] [hydroxy(phosphonooxy)phosphoryl] hydrogen phosphate. Canonical SMILES: C1=CN(C(=O)N=C1N)C2C(C(C(O2)NOP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O. Product ID: ACM2226746. Alfa Chemistry ISO 9001:2015 Certified. Categories: 5'-Azacytidine 5'-triphosphate. |  |
| 5-Azacytidine 98+% (HPLC) | 5-Azacytidine 98+% (HPLC). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 5g, 25g. US Biological Life Sciences. | Worldwide |
| 2',3',5'-triacetyl-5-azacytidine | 5-Azacytidine is an inhibitor of DNA methyltransferase, potentially serving to reverse epigenetic changes. 2',3',5'-triacetyl-5-Azacytidine is a prodrug form of 5-azacytidine. Synonyms: 5-Azacytidine 2',3',5'-O-triacetate; 2',3',5'-Triacetate-4-amino-1-β-D-ribofuranosyl-s-triazin-2(1H)-one; 2',3',5'-Tri-O-acetyl-5-Azacitidine; NSC 291930; 4-Amino-1-(2,3,5-tri-O-acetyl-β-D-ribofuranosyl)-1,3,5-triazin-2(1H)-one. Grade: ≥98% by HPLC. CAS No. 10302-78-0. Molecular formula: C14H18N4O8. Mole weight: 370.31. | |
| 2',3',5'-Tri-O-(4-chlorobenzoyl) 5-Azacytidine | The biomedical compound, 2',3',5'-Tri-O-(4-chlorobenzoyl) 5-Azacytidine, has emerged as a revolutionary treatment option for diverse ailments, including cancer. By effectively curtailing DNA methyltransferase activity, this potent pharmaceutical entity induces DNA demethylation, thereby revitalizing tumor suppressor genes that were once dormant. Prominently employed in the realm of epigenetic therapy, it exhibits remarkable efficacy in combatting hematological malignancies, unraveling new prospects in the medical landscape. Molecular formula: C29H21Cl3N4O8. Mole weight: 659.86. | |
| 2',3',5'-Tri-O-(4-chlorobenzoyl) 5-Azacytidine-15N4 | 2',3',5'-Tri-O-(4-chlorobenzoyl) 5-Azacytidine-15N4. Molecular formula: C29H21Cl3[15N]4O8. Mole weight: 663.83. | |
| 2'-O-Acetyl-5-azacytidine | 2'-O-Acetyl-5-azacytidine is structurally similar and can be converted to the FDA-appproved azacitidine which is a DNA metnyltransferase (DNMT) inhibitor for treating myelodysplastic syndromes (MDS). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg, 25mg. Molecular Formula: C10H14N4O6, Molecular Weight: 286.24. US Biological Life Sciences. | Worldwide |
| 6-Amino-5-azacytidine | 6-Amino-5-azacytidine is a nucleoside that exhibits a growth-inhibitory effect in humans and interferes with the metabolism of purines. 6-Amino-5-azacytidine is also a derivative of 5-Azacytidine, a chemotherapeutic agent used to treat patients with acute myelogenous leukemia. Synonyms: 4,6-Diamino-1-β-D-ribofuranosyl-1,3,5-triazin-2(1H)-one. CAS No. 105331-00-8. Molecular formula: C8H13N5O5. Mole weight: 259.22. | |
| 6-Amino-5-azacytidine-15N3 | 6-Amino-5-azacytidine-15N3 is a labelled analogue of 6-Amino-5-azacytidine. 6-Amino-5-azacytidine is a nucleoside that exhibits a growth-inhibitory effect in humans and interferes with the metabolism of purines. 6-Amino-5-azacytidine is also a derivative of 5-Azacytidine, a chemotherapeutic agent used to treat patients with acute myelogenous leukemia. Synonyms: 4,6-Diamino-1-β-D-ribofuranosyl-1,3,5-triazin-2(1H)-one-15N3. Molecular formula: C8H13N2[15N]3O5. Mole weight: 262.2. | |
| 1,4-Dibenzoyl-3-thio-semicarbazide | is an intermediate in synthesizing 1- β-D-Ribofuranosyl-3-aminocarbonyl Guandinine (R415500), which is an impurity of 5-Azacytidine (A796000). 5-Azacytidine is a potent growth inhibitor and cytotoxic agent. 5-Azacytidine acts as a demethylating agent by inhibiting DNA methyltransferase. Group: Biochemicals. Grades: Highly Purified. CAS No. 58975-55-6. Pack Sizes: 25g, 50g. Molecular Formula: C15H13N3O2S. US Biological Life Sciences. | Worldwide |
| 1-(5-O-Acetyl- β-D-ribofuranosyl)-4-amino-1,3,5-triazin-2(1H)-one | 1-(5-O-Acetyl- β-D-ribofuranosyl)-4-amino-1,3,5-triazin-2(1H)-one is an impurity of 5-Azacytidine (A796000), a potent growth inhibitor and cytotoxic agent. It acts as a demethylating agent by inhibiting DNA methyltransferase. Group: Biochemicals. Grades: Highly Purified. CAS No. 1174733-90-4. Pack Sizes: 10mg, 100mg. Molecular Formula: C10H14N4O6. US Biological Life Sciences. | Worldwide |
| 1- β-D-Ribofuranosyl-3-aminocarbonyl Guandinine | 1- β-D-Ribofuranosyl-3-aminocarbonyl Guandinine is an impurity of 5-Azacytidine (A796000) which is a potent growth inhibitor and cytotoxic agent. 5-Azacytidine acts as a demethylating agent by inhibiting DNA methyltransferase. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 10mg. Molecular Formula: C7H14N4O5, Molecular Weight: 234.21. US Biological Life Sciences. | Worldwide |
| 1- β-D-Ribofuranosyl-3-iminohydroxymethyl Guandinine | 1- β-D-Ribofuranosyl-3-iminohydroxymethyl Guandinine is an impurity of 5-Azacytidine (A796000) which is a potent growth inhibitor and cytotoxic agent. 5-Azacytidine acts as a demethylating agent by inhibiting DNA methyltransferase. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 10mg. Molecular Formula: C7H14N4O5, Molecular Weight: 234.21. US Biological Life Sciences. | Worldwide |
| 1-D-Ribofuranosyl-3-guanylurea (α/β-Mixture) | A labile hydrolysis product of the antitumor nuceloside 5-Azacytidine. Synonyms: N-(aminoiminomethyl)-N'-D-ribofuranosylurea; 1-Amidino-3-D-ribofuranosylurea. Grade: 95%. Molecular formula: C7H14N4O5. Mole weight: 234.21. | |
| 2',3',5'-Tribenzoate D-Ribofuranosyl-urea | 2',3',5'-Tribenzoate D-Ribofuranosyl-urea, a by-product compound produced during the syntheses of 1-β-D-Ribofuranosyl-3-aminocarbonyl Guandinine, that is an impurity of 5-Azacytidine. 5-Azacytidine is a potent growth inhibitor and cytotoxic agent. 5-Azacytidine acts as a demethylating agent by inhibiting DNA methyltransferase. Synonyms: D-Ribofuranosyl-urea Tribenzoate; (2,3,5-Tri-O-benzoyl-D-ribofuranosyl)-urea; [(2R,3R,4R)-3,4-dibenzoyloxy-5-(carbamoylamino)oxolan-2-yl]methylbenzoate; Urea, D-ribofuranosyl-, 2',3',5'-tribenzoate. Molecular formula: C27H24N2O8. Mole weight: 504.49. | |
| 2',3',5'-Tribenzoate D-Ribofuranosyl-urea | 2',3',5'-Tribenzoate D-Ribofuranosyl-urea is a by-product compound produced during the syntheses of 1- β-D-Ribofuranosyl-3-aminocarbonyl Guandinine (R415500), which is an impurity of 5-Azacytidine (A796000). 5-Azacytidine is a potent growth inhibitor and cytotoxic agent. 5-Azacytidine acts as a demethylating agent by inhibiting DNA methyltransferase. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 50mg, 100mg. Molecular Formula: C27H24N2O8. US Biological Life Sciences. | Worldwide |
| 2,3,5-tri-O-acetylribofuranose | 2,3,5-tri-O-acetylribofuranose is an impurity of 5-Azacytidine, an antiproliferative/cytotoxic agent for leukemia therapy. Synonyms: (2R,3R,4R)-2-(acetoxymethyl)-5-hydroxytetrahydrofuran-3,4-diyl diacetate; 2,3,5-Tri-O-acetyl-β-D-ribofuranose. CAS No. 65024-85-3. Molecular formula: C11H16O8. Mole weight: 276.24. | |
| 2-[ (Benzoylimino) (methylthio) methyl]hydrazide Benzoic Acid | 2-[ (Benzoylimino) (methylthio) methyl]hydrazide Benzoic Acid is an intermediate in synthesizing 1- β-D-Ribofuranosyl-3-aminocarbonyl Guandinine (R415500), which is an impurity of 5-Azacytidine (A796000). 5-Azacytidine is a potent growth inhibitor and cytotoxic agent. 5-Azacytidine acts as a demethylating agent by inhibiting DNA methyltransferase. Group: Biochemicals. Grades: Highly Purified. CAS No. 74074-45-6. Pack Sizes: 25g, 50g. Molecular Formula: C16H15N3O2S. US Biological Life Sciences. | Worldwide |
| (2R,3R,4R,5R)-2-(4-amino-2-oxo-1,3,5-triazin-1(2H)-yl)-5-(hydroxyl methyl)tetrahydrofuran-3,4-diyl diacetate | (2R,3R,4R,5R)-2-(4-amino-2-oxo-1,3,5-triazin-1(2H)-yl)-5-(hydroxyl methyl)tetrahydrofuran-3,4-diyl diacetate is an impurity of 5-Azacytidine, an antiproliferative/cytotoxic agent for leukemia therapy. Synonyms: (2R,3R,4R,5R)-2-(4-Amino-2-oxo-1,3,5-triazin-1(2H)-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diyl diacetate; 1415316-72-1. CAS No. 1415316-72-1. Molecular formula: C12H16N4O7. Mole weight: 328.28. | |
| 4-amino-1-((2S,3S,4R,5S)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1,3,5-triazin-2(1H)-one | 4-amino-1-((2S,3S,4R,5S)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1,3,5-triazin-2(1H)-one is an impurity of 5-Azacytidine, an antiproliferative/cytotoxic agent for leukemia therapy. Synonyms: L-5-Azacytidine. CAS No. 206269-46-7. Molecular formula: C8H12N4O5. Mole weight: 244.20. | |
| 6-Methyl-5-azacytosine pentose | 6-Methyl-5-azacytosine pentose is an impurity of 5-Azacytidine, an antiproliferative/cytotoxic agent for leukemia therapy. Synonyms: 4-amino-1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-6-methyl-1,3,5-triazin-2(1H)-one; 6-Methyl-5-azacytidine. CAS No. 105330-94-7. Molecular formula: C9H14N4O5. Mole weight: 258.23. | |
| Azacetidine Monoacetate | Azacetidine Monoacetate is an impurity of 5-Azacytidine, an antiproliferative/cytotoxic agent for leukemia therapy. Synonyms: ((2R,3S,4R,5R)-5-(4-amino-2-oxo-1,3,5-triazin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl acetate; 1-(5-O-Acetyl-β-D-ribofuranosyl)-4-amino-1,3,5-triazin-2(1H)-one. CAS No. 1174733-90-4. Molecular formula: C10H14N4O6. Mole weight: 286.24. | |
| Azacitidine | 4-Amino-1-β-D-ribofuranosyl-1,3,5-triazin-2(1H)-one sodium 4-Amino-1-(β-D-ribofuranosyl)-1,3,5-triazin-2(1H)-one, 5-Azacytidine, Ladakamycin. CAS No. 320-67-2. Product ID: 8-04982. Molecular formula: C8H12N4O5. Mole weight: 244.2. Purity: nucleoside metabolic inhibitor therapeutic for acute myeloid leukemia. |  |
| (β)-1-D-Ribofuranosyl-3-guanylurea | (α)-1-D-Ribofuranosyl-3-guanylurea is a labile hydrolysis product of the antitumor nuceloside 5-Azacytidine. Synonyms: N-(Aminoiminomethyl)-N'-β-D-ribofuranosylurea; 1-β-D-Ribofuranosyl-3-guanylurea; NSC 264412; 1-(Diaminomethylidene)-3-[(2R,3R,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]urea; 3-Carbamimidoyl-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]urea. Grade: 96 %. CAS No. 2508-80-7. Molecular formula: C7H14N4O5. Mole weight: 234.21. | |
| Cytidine deaminase from Human, recombinant | CDA (Cytidine deaminase) is an enzyme that scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis. This protein is one of several deaminases responsible for maintaining the cellular pyrimidine pool. The protein also catalyzes the deamination of chemotherapeutic cytosine nucleoside analogs such as Ara-C and 5-azacytidine, which results in the loss of their cytotoxic and antitumor function. It can form homotetramers and is mainly expressed in granulocytes. Recombinant human CDA protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. Group: Enzymes. Synonyms: CDA; CDD; Cytidine aminohydrolase; Cytosine nucleoside deaminase. Enzyme Commission Number: EC 3.5.4.5. Purity: > 90% by SDS-PAGE. Mole weight: 18.3 kDa (166 aa, 1-146 aa + His Tag). Activity: > 3.5 unit/mg. Storage: Can be stored at 4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles. Form: Liquid. Source: E. coli. Species: Human. CDA; CDD; Cytidine aminohydrolase; Cytosine nucleoside deaminase; Cytidine deaminase. Cat No: NATE-1668. |  |
| D-2'-Deoxyribofuranosyl-3-guanylurea (α/β-Mixture) | D-2'-Deoxyribofuranosyl-3-guanylurea is used in the synthesis of N4-alkyl-5-azacytidines as mutagenic agents. Synonyms: N-(Aminoiminomethyl)-N-(2-deoxy-D-erythro-pentofuranosyl)urea; Decitabine deformyl impurity formate; Urea, N-(aminoiminomethyl)-N'-(2-deoxy-D-erythro-pentofuranosyl)-; N-(Aminoiminomethyl)-N'-(2-deoxy-D-erythro-pentofuranosyl)urea. Grade: > 95%. CAS No. 570410-72-9. Molecular formula: C7H14N4O4. Mole weight: 218.21. | |
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