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| Product | Description | |
|---|---|---|
| 5-Methylcytosine | 5-Methylcytosine is a well-characterized DNA modification, and is also predominantly in abundant non-coding RNAs in both prokaryotes and eukaryotes. 5-Methylcytosine in mRNA is a new epitranscriptome marker inArabidopsis, and that regulation of this modification is an integral part of gene regulatory networks underlying plant development [1]. Uses: Scientific research. Group: Natural products. CAS No. 554-01-8. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g. Product ID: HY-W008091. |  |
| 5-Methylcytosine HCl | 5-Methylcytosine HCl. Group: Biochemicals. Grades: Highly Purified. CAS No. 58366-64-6. Pack Sizes: 1g, 2g, 5g, 10g, 25g. Molecular Formula: C5H7N3O·HCl. US Biological Life Sciences. |  Worldwide |
| 5-Methylcytosine hydrochloride | 5-Methylcytosine hydrochloride. Group: other glass and ceramic materials. CAS No. 58366-64-6. Product ID: 6-amino-5-methyl-1H-pyrimidin-2-one; hydrochloride. Molecular formula: 161.59g/mol. Mole weight: C5H8ClN3O. CC1=C(NC(=O)N=C1)N.Cl. InChI=1S/C5H7N3O. ClH/c1-3-2-7-5(9)8-4(3)6; /h2H, 1H3, (H3, 6, 7, 8, 9); 1H. ANWMULVRPAUPJT-UHFFFAOYSA-N. >98.0%(LC). |  |
| 5-Methylcytosine Hydrochloride (4-Amino-2-hydroxy-5-methyl-pyrimidine Hydrochloride) | 5-Methylcytosine Hydrochloride (4-Amino-2-hydroxy-5-methyl-pyrimidine Hydrochloride). Group: Biochemicals. Alternative Names: 4-Amino-2-hydroxy-5-methyl-pyrimidine Hydrochloride. Grades: Highly Purified. Pack Sizes: 500mg. US Biological Life Sciences. | Worldwide |
| 5-Hydroxymethylcytidine | 5-Hydroxymethylcytosine is a DNA pyrimidine nitrogen base. It is formed from the DNA base cytosine by adding a methyl group and then a hydroxy group. It is important in epigenetics, because the hydroxymethyl group on the cytosine can possibly switch a gene on and off. It was first seen in bacteriophages in 1952.[1][2] However, in 2009 it was found to be abundant in human and mouse brains,[3] as well as in embryonic stem cells.[4] In mammals, it can be generated by oxidation of 5-methylcytosine, a reaction mediated by the Tet family of enzymes. 5-Hydroxymethylcytidine is a product in DNA hydroxymethylation. The concentrations of 5-Hydroxymethylcytidine in the brain were used to study Alzheimers disease. Group: Biochemicals. Grades: Highly Purified. CAS No. 19235-17-7. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
| 5-Hydroxymethylcytosine | 5-Hydroxymethylcytosine (5hmC) is an oxidized forms of 5-methylcytosine (5mC) in mammalian DNA. 5-Hydroxymethylcytosine is produced from 5mC in an enzymatic pathway involving three 5mC oxidases, Ten-eleven translocation (TET)1, TET2, and TET3. The conversion of 5mC into 5hmC can be the first step in a pathway leading towards DNA demethylation. 5-Hydroxymethylcytosine is associated with gene transcription and frequently used as a mark to investigate dynamic DNA methylation conversion during mammalian development [1]. Uses: Scientific research. Group: Natural products. Alternative Names: 5hmC. CAS No. 1123-95-1. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-W018324. | |
| 5-Methylcytidine-5'-monophosphate | 5-methylcytidine 5'-monophosphate is a pyrimidine ribonucleoside 5'-monophosphate having 5-methylcytosine as the nucleobase. It derives from a cytidine 5'-monophosphate. Synonyms: 5-Methyl-CMP; m5CMP; 5-Methylcytidylic acid; 5-methylcytidine 5'-(dihydrogen phosphate); ((2R,3S,4R,5R)-5-(4-Amino-5-methyl-2-oxopyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl dihydrogen phosphate; Cytidine, 5-methyl-, 5'-(dihydrogen phosphate). Grades: ≥95% by HPLC. CAS No. 3590-36-1. Molecular formula: C10H16N3O8P. Mole weight: 337.22. |  |
| Ac-rC(5-Me) Phosphoramidite | Ac-rC(5-Me) Phosphoramidite: a highly specialized chemical reagent, meticulously crafted for the intricacies of solid-phase synthesis of modified RNA molecules. With its unique capability for integrating 5-methylcytosine into RNA strands, Ac-rC(5-Me) Phosphoramidite is the go-to tool for researchers seeking to investigate the complex dynamics of RNA stability and epigenetic regulation. Amplify your understanding of the intricate interplay of biochemical systems with the expertly designed, scientifically rigorous Ac-rC(5-Me) Phosphoramidite. Synonyms: DMT-2'-O-TBDMS-5-methyl-rC(ac) Phosphoramidite; N-Acetyl-5-methyl-5'-O-(4,4-dimethoxytrityl)-2'-O-[(tert-butyl)dimethylsilyl]cytidine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite; 2'-O-(tert-Butyldimethylsilyl)-3'-O-[(diisopropylamino)(2-cyanoethoxy)phosphino]-5'-O-(4,4'-dimethoxytrityl)-N4-acetyl-5-methylcytidine. Molecular formula: C48H66N5O9PSi. Mole weight: 916.14. | |
| cytosine deaminase | Also acts on 5-methylcytosine. Group: Enzymes. Synonyms: isocytosine deaminase. Enzyme Commission Number: EC 3.5.4.1. CAS No. 9025-5-2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4536; cytosine deaminase; EC 3.5.4.1; 9025-05-2; isocytosine deaminase. Cat No: EXWM-4536. |  |
| dT-Me Phosphoramidite | The dT-Me Phosphoramidite, a compound commonly utilized in the solid-phase synthesis of oligonucleotides incorporating methylated nucleosides, like 5-methylcytosine and N4-methylcytosine, has the propensity to improve the stability of RNA and DNA molecules. Therein lies the potential for a game-changing effect on the development of innovative treatments for challenging diseases such as cancer, viral infections or genetic disorders. Synonyms: 5'-Dimethoxytrityl-2'-deoxyThymidine, 3'-[(methyl)-(N,N-diisopropyl)]-phosphoramidite. CAS No. 84416-85-3. Molecular formula: C38H48N3O8P. Mole weight: 705.79. | |
| multisite-specific tRNA:(cytosine-C5)-methyltransferase | The enzyme from Saccharomyces cerevisiae is responsible for complete 5-methylcytosine methylations of yeast tRNA. The incidence of modification depends on the cytosine position in tRNA. At positions 34 and 40, 5-methylcytosine is found only in two yeast tRNAs (tRNALeu(CUA) and tRNAPhe(GAA), respectively), whereas most other elongator yeast tRNAs bear either 5-methylcytosine48 or 5-methylcytosine49, but never both in the same tRNA molecule. The formation of 5-methylcytosine34 and 5-methylcytosine40 is a strictly intron-dependent process, whereas the formation of 5-methylcytosine48 and 5-methylcytosine49 is an intron-independent process. Group: Enzymes. Synonyms: multisite-specific tRNA:m5C-methyltransferase; TRM4 (gene name, gene corresponding to ORF YBL024w). Enzyme Commission Number: EC 2.1.1.202. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1803; multisite-specific tRNA:(cytosine-C5)-methyltransferase; EC 2.1.1.202; multisite-specific tRNA:m5C-methyltransferase; TRM4 (gene name, gene corresponding to ORF YBL024w). Cat No: EXWM-1803. | |
| tRNA (cytosine34-C5)-methyltransferase | The human enzyme is specific for C5-methylation of cytosine34 in tRNA precursors. The intron in the human pre-tRNALeu(CAA) is indispensable for the C5-methylation of cytosine in the first position of the anticodon. It is not able to form 5-methylcytosine at positions 48 and 49 of human and yeast tRNA precursors. Group: Enzymes. Synonyms: hTrm4 Mtase; hTrm4 methyltransferase; hTrm4 (gene name); tRNA:m5C-methyltransferase (ambiguous). Enzyme Commission Number: EC 2.1.1.203. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1804; tRNA (cytosine34-C5)-methyltransferase; EC 2.1.1.203; hTrm4 Mtase; hTrm4 methyltransferase; hTrm4 (gene name); tRNA:m5C-methyltransferase (ambiguous). Cat No: EXWM-1804. | |
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