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| Product | Description | |
|---|---|---|
| Lonidamine | Lonidamine (AF-1890) is a hexokinase and mitochondrial pyruvate carrier inhibitor ( K i : 2.5 μM). Lonidamine also inhibits aerobic glycolysis in cancer cells. Lonidamine can be used in the research of mitochondrial metabolism and inflammation, such as pulmonary fibrosis [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AF-1890; Diclondazolic Acid; DICA. CAS No. 50264-69-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-B0486. |  |
| Lonidamine | Lonidamine. Group: Biochemicals. Grades: Purified. CAS No. 50264-69-2. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. |  Worldwide |
| Lonidamine | Lonidamine is a derivative of indazole-3-carboxylic acid, which for a long time, has been known to inhibit aerobic glycolysis in cancer cells. It seems to enhance aerobic glycolysis in normal cells, but suppress glycolysis in cancer cells. This is most likely through the inhibition of the mitochondrially bound hexokinase. Later studies in Ehrlich ascites tumor cells showed that lonidamine inhibits both respiration and glycolysis leading to a decrease in cellular ATP. Synonyms: DICA; Diclondazolic acid; Doridamina; AF 1890; AF1890; AF-1890; Lonidamine. Grade: >98%. CAS No. 50264-69-2. Molecular formula: C15H10Cl2N2O2. Mole weight: 321.16. |  |
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