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| Product | Description | |
|---|---|---|
| 7,3',4'-Trihydroxyisoflavone | 7,3',4'-Trihydroxyisoflavone, a major metabolite of Daidzein, is an ATP-competitive inhibitor of Cot (Tpl2/MAP3K8) and MKK4. 7,3',4'-Trihydroxyisoflavone has anticancer, anti-angiogenic, chemoprotective, and free radical scavenging activities [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 485-63-2. Pack Sizes: 10 mM * 1 mL; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-124953. |  |
| 7,3',4'-Trihydroxyisoflavone (3-(3,4-Dihydroxyphenyl)-7-hydroxy-4H-chromen-4-one, 3-Hydroxydiadzein, THIF, 7,3,4-THIF) | An ATP-competitive inhibitor of Cot and MKK4 that subsequently suppresses UVB-induced COX-2 expression in JB6 P+ mouse epidermal cells. Group: Biochemicals. Grades: Highly Purified. CAS No. 485-63-2. Pack Sizes: 25mg, 100mg. US Biological Life Sciences. |  Worldwide |
| 3',4',7-Trihydroxyisoflavone | 3',4',7-Trihydroxyisoflavone. Group: Biochemicals. Alternative Names: 3-(3,4-Dihydroxyphenyl)-7-hydroxy-4H-1-benzopyran-4-one. Grades: Highly Purified. CAS No. 485-63-2. Pack Sizes: 100mg, 250mg, 500mg, 1g, 2g. Molecular Formula: C15H10O5. US Biological Life Sciences. | Worldwide |
| 3,4,7-Trihydroxyisoflavone | Inhibits b-galactosidase enzyme. Group: Biochemicals. Grades: Highly Purified. CAS No. 485-63-2. Pack Sizes: 100mg. US Biological Life Sciences. | Worldwide |
| Genistein-2,3,5,6-d4 (4',5,7-Trihydroxyisoflavone-2,3,5,6-d4) | Exhibits specific inhibitory activity against tyrosine kinases,including autophosphorylation of epidermal growth factor receptor kinase (IC50-2.6uM). Also i. Group: Biochemicals. Alternative Names: 4',5,7-Trihydroxyisoflavone-2,3,5,6-d4. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Desmethylglycitein | Desmethylglycitein (4',6,7-Trihydroxyisoflavone), a metabolite of daidzein, sourced from Glycine max with antioxidant, and anti-cancer activities.Desmethylglycitein binds directly to CDK1 and CDK2 in vivo, resulting in the suppresses CDK1 and CDK2 activity. Desmethylglycitein is a direct inhibitor of protein kinase C (PKC)α, against solar UV (sUV)-induced matrix matrix metalloproteinase 1 (MMP1). Desmethylglycitein binds to PI3K in an ATP competitive manner in the cytosol, where it inhibits the activity of PI3K and downstream signaling cascades, leading to the suppression of adipogenesis in 3T3-L1 preadipocytes. Uses: Designed for use in research and industrial production. Product Category: Inhibitors. CAS No. 17817-31-1. Molecular formula: C15H10O5. Mole weight: 270.24. Purity: 0.95. Product ID: ACM17817311. Alfa Chemistry ISO 9001:2015 Certified. |  |
| Genistein | 4,5,7-Trihydroxyisoflavone. cytotoxic inhibitor of tyrosine kinase and topoisomerase II kinase. CAS No. 446-72-0. Product ID: 1-01014. Molecular formula: C15H10O5. Mole weight: 270.23. Purity: 0.98. Reference: Merck 12, 4395; Cancer Res., 58, 4851, 1998; J. Biol. Chem., 262, 5592, 1987; Nature, 353, 558, 1991. |  |
| Genistein | Cell-permeable, reversible, substrate competitive tyrosine kinase inhibitor (including EGFR phosphorylation), implicated in almost all cell growth and proliferation signal cascades. Inhibitor of mammalian DNA topoisomerase II. Anticancer agent, inducing cell cycle arrest and apoptosis. Antiangiogenic agent, down-regulates the transcription of genes involved in controlling angiogenesis. Binds estrogen receptor beta. Can increase the rate of growth of some ER expressing breast cancers. Potent alpha-glucosidase inhibitor. Anthelmintic. Anti-diabetic. Activates nuclear receptors, oestrogen receptors and peroxisome proliferator-activated receptors (all PPAR isoforms) and it inhibits various enzyme activities. Inhibitor of GLUT4-mediated glucose uptake in 3T3-L1 adipocytes. Stimulator of autophagy vacuolization. Antioxidant. TRAIL sensitizer. Acts as an agonist at the GPR30 receptor. DNA methyltransferase inhibitor. Genistein exhibits synergistic antibacterial effects on MRSA. Group: Biochemicals. Alternative Names: NSC 36586; Baichanin A; Differenol A; 4',5,7-Trihydroxyisoflavone; 5,7-Dihydroxy-3-(4-hydroxyphenyl)-4H-1-benzopyran-4-one. Grades: Highly Purified. CAS No. 446-72-0. Pack Sizes: 10mg, 50mg, 250mg. Molecular Formula: C??H??O?. US Biological Life Sciences. | Worldwide |
| Genistein | Genistein, a phytoestrogen found in soy products, is a highly specific inhibitor of protein tyrosine kinase (PTK) which blocks the mitogenic effect mediated by EGF on NIH-3T3 cells with IC50 of 12μM or by insulin with IC50 of 19 μM. Genistein is developed to be an antitumor agent. Genistein has antioxidant effect, it can be used in cosmetics material. Uses: Antitumor agent. Synonyms: 5,7-Dihydroxy-3-(4-hydroxyphenyl)-4H-1-benzopyran-4-one; Baichanin A; Bonistein; 4',5,7-Trihydroxyisoflavone; GeniVida; Genisteol; NSC 36586; Prunetol; Sophoricol; Differenol A. Grades: >98%. CAS No. 446-72-0. Molecular formula: C15H10O5. Mole weight: 270.24. |  |
| Genistein | United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standardspharma & vet compounds & metabolitespharma & vet compounds & metabolitesapi standardsenzyme activators, inhibitors & substrates. Alternative Names: Bonistein, 5,7,4'-Trihydroxyisoflavone, Genistin aglycone, Climagen F, FW 635I-2, Prunetol, 5,7-Dihydroxy-3-(4-hydroxyphenyl)-4H-1-benzopyran-4-one, NSC 36586, Genisteol, NPI 031L, Sophoricol,4H-1-Benzopyran-4-one, 5,7-dihydroxy-3-(4-hydroxyphenyl)-, SIPI 807-1, Genistein (6CI), GeniVida, 4',5,7-Trihydroxyisoflavone, 5,7-Dihydroxy-3-(4-hydroxyphenyl)-4H-chromen-4-one, C.I. 75610, Genisterin, Isoflavone, 4',5,7-trihydroxy- (8CI), Baichanin A. |  |
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